Research Report
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2019
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2020
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2021
- http://research.umh.es/vivo/pub/proyecto/GAN956477
- http://research.umh.es/vivo/pub/proyecto/PID2020113112RBI00
- http://research.umh.es/vivo/pub/proyecto/PID2020117294RBI00
- http://research.umh.es/vivo/pub/proyecto/PID2020117569RAI00
- http://research.umh.es/vivo/pub/proyecto/PROMETEO2021031
- http://research.umh.es/vivo/pub/proyecto/PROMETEO2021033
- http://research.umh.es/vivo/pub/proyecto/PROMETEO2021059
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academic article
- A Nudibranch Marine Extract Selectively Chemosensitizes Colorectal Cancer Cells by Inducing ROS-Mediated Endoplasmic Reticulum Stress
- A capsaicinoid¿based soft drug, AG1529, for attenuating TRPV1¿mediated histaminergic and inflammatory sensory neuron excitability
- An N-terminal half fragment of the histidine phosphocarrier protein, HPr, is disordered but binds to HPr partners and shows antibacterial properties
- Antibacterial plant compounds, extracts and essential oils: An updated review on their effects and putative mechanisms of action
- Antiviral Function of NKEF against VHSV in Rainbow Trout
- Bisphenol-S and Bisphenol-F alter mouse pancreatic ß-cell ion channel expression and activity and insulin release through an estrogen receptor ERß mediated pathway.
- Bound galloylated compounds in persimmon upcycled dietary fiber modulate microbial strains associated to human health after in vitro digestion
- CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model
- CLytA-DAAO Chimeric Enzyme Bound to Magnetic Nanoparticles. A New Therapeutical Approach for Cancer Patients?
- Carotenoids from persimmon (Diospyros kaki Thunb.) byproducts exert photoprotective, antioxidative and microbial anti-adhesive effects on HaCaT
- DD04107-Derived neuronal exocytosis inhibitor peptides: evidences for synaptotagmin-1 as a putative target.
- Delta opioid receptor in astrocytes contributes to neuropathic cold pain and analgesic tolerance in female mice
- Diagnostic yield of early repeat colonoscopy after suboptimal bowel preparation in a fecal immunochemical test-based screening program.
- ERK5 Signaling Pathway Is A Novel Target Of Sorafenib: Implication In EGF Biology.
- Editorial: CD4+ T Cells in Cancer Immunotherapies.
- Editorial: Development of Functional Foods From Marine Sources
- Effect of Metabolaid® on pre- and stage 1 hypertensive patients: A randomized controlled trial
- Effectiveness of a Multicomponent Group Psychological Intervention Program in Patients with Inflammatory Bowel Disease:
- Effects of Somatic Methylation in Colonic Polyps on Risk of Developing Metachronous Advanced Colorectal Lesions.
- Endocrine disruption in Crohn's disease: Bisphenol A enhances systemic inflammatory response in patients with gut barrier translocation of dysbiotic microbiota products
- Evolution of the emotional impact in patients with early inflammatory bowel disease during and after Covid-19 lockdown
- Formation of Multicolor Nanogels Based on Cationic Polyfluorenes and Poly(methyl vinyl ether-alt-maleic monoethyl ester): Potential Use as pH-Responsive Fluorescent Drug Carriers
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
- High global anti-oxidant protection and stimulation of the collagen synthesis of new anti-age product containing an optimized active-mix
- Immunomodulatory Lectin-like Peptides for Fish Erythrocytes-Targeting as Potential Antiviral Drug Delivery Platforms
- Induction of foxp3 during the Crosstalk between Antigen Presenting Like-Cells MHCII + CD83 + and Splenocytes CD4 + IgM - in Rainbow Trout
- Kappa opioid receptor modulation of endometriosis pain in mice
- L-Menthol-loadable electrospun fibers of PMVEMA anhydride for topical administration
- Lung Cancer Management with Silibinin: A Historical and Translational Perspective
- Metformin Is a Pyridoxal-5¿-phosphate (PLP)-Competitive Inhibitor of SHMT2
- Micro-/Nano-Structure Ceramic scaffolds that mimic natural cancellous bone
- Modulation of the tissue expression pattern of zebrafish crp-like molecules suggests a relevant antiviral role in fish skin
- Peimine, an anti-inflammatory compound from Chinese herbal extracts, modulates muscle-type nicotinic receptors.
- Phenylalanine-derived beta-Lactam TRPM8 modulators. Configuration effect on the antagonist activity
- Potential of persimmon dietary fiber obtained from byproducts as antioxidant, prebiotic and modulating agent of the intestinal epithelial barrier function
- Probing the Structural Dynamics of the Activation Gate of KcsA Using Homo-FRET Measurements
- Residual helicity at the active site of the histidine phosphocarrier, HPr, modulates binding affinity to its natural partners
- Reusable Fluorescent Nanobiosensor Integrated in a Multiwell Plate for Screening and Quantification of Antidiabetic Drugs
- Role of the endocannabinoid system in a mouse model of Fragile X undergoing neuropathic pain
- Rose petal effect: A subtle combination of nano-scale roughness and chemical variability
- Seroprevalence Study and Cross-Sectional Survey on COVID-19 for a Plan to Reopen the University of Alicante (Spain)
- Simplified risk-prediction for benchmarking and quality improvement in emergency general surgery. Prospective, multicenter, observational cohort study
- Simvastatin in the Prevention of Recurrent Pancreatitis: Design and Rationale of a Multicenter Triple-Blind Randomized Controlled Trial, the SIMBA Trial
- Structural and in vitro functional characterization of a menthyl TRPM8 antagonist indicates species-dependent regulation
- Synergism between oral paracetamol and nefopam in a murine model of postoperative pain
- Tetraoctylammonium, a Long Chain Quaternary Ammonium Blocker, Promotes a Noncollapsed, Resting-Like Inactivated State in KcsA
- The CB2 cannabinoid receptor as a therapeutic target in the central nervous system
- The Impact of Tregs on the Anticancer Immunity and the Efficacy of Immune Checkpoint Inhibitor Therapies
- The Multifaceted Role of Th1, Th9, and Th17 Cells in Immune Checkpoint Inhibition Therapy
- The armadillo-repeat domain of plakophilin 1 binds the C-terminal sterile alpha motif (SAM) of p73
- The effects of aging on male mouse pancreatic ß-cell function involve multiple events in the regulation of secretion: influence of insulin sensitivity
- The muscle-relaxing C-terminal peptide from troponin I populates a nascent helix, facilitating binding to tropomyosin with a potent therapeutic effect
- The second-generation antipsychotic drug aripiprazole modulates the serotonergic system in pancreatic islets and induces beta cell dysfunction in female mice
- Update on the inactivation procedures for the vaccine development prospects of a new highly virulent RGNNV isolate
- Ventricular Fibrosis and Coronary Remodeling Following Short-Term Exposure of Healthy and Malnourished Mice to Bisphenol A
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book
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chapter
- Chapter Five - Physiology of pancreatic ß-cells: Ion channels and molecular mechanisms implicated in stimulus-secretion coupling
- Experiencias y reflexiones sobre la docencia en la ingeniería en tiempos de COVID-19. Lecciones aprendidas
- Formación Transversal y Trabajos Fin de Grado Interdisciplinares
- Formación en competencias transversales para la realización de Trabajos Fin de Grado Interdisciplinares
- The pleiotropic functions of Oncorhynchus mykiss Red Blood Cells
- Type I interferons as key players in pancreatic ß-cell dysfunction in type 1 diabetes
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congress communication
- 1(2-((4-Hydroxy-2-Iodo-5-Methoxybenzyl) Amino)-2-Oxoethyl Dodecanoate (AG1529) a Soft Capsaicinoid Reduces Capsaicin Receptor (TRPV1)-mediated Inflammatory and Histaminergic Nociceptor Excitability
- Caracterización biofísica de posibles inhibidores del complejo NS2B-NS3pro de ZIKV
- A European integrated testing strategy for identifying hazards of endocrine disruptors: the pancreatic human ß-cell model
- Actividad antiviral de materiales poliméricos con nanopartículas metálicas
- Alterations of TRP and NaV channels in chemotherapy-induced peripheral neuropathy: Studying their role using in vitro pre-clinical nociceptor models
- Androgenic TRPM8 activity drives sexual dimorphism in a murine model of chronic migraine
- Antiviral activity of Mediterranean aromatic plants against viruses of importance in aquaculture
- BPA requires ERalpha, ERbeta, and GPER to induce apoptosis in the rat ß-cell line INS-1E
- Bidirectional crosstalk during the gating of KcsA revealed by homo-FRET methodologies
- Búsqueda de péptidos de unión a eritrocitos de peces para el desarrollo de nuevos sistemas terapéuticos o profilácticos en acuicultura
- Caracterización biofísica de posibles inhibidores del complejo NS2BNS3pro de ZIKV
- Carotenoid extraction and revalorization of by-products derived from persimmon juice processing
- DISEÑO DE UN BIOSENSOR FLUORESCENTE DE A-GLUCOSIDASA BASADO EN NANOPARTÍCULAS COMPUESTAS POR LÍPIDO Y POLÍMERO CONJUGADO
- Derivados no abrasivos del capsicum: nueva generación de anti-inflamatorios y anti-pruriginosos no inmunosupresores para el tratamiento de patologías cutáneas y cuidado de la piel sensible o reactiva
- Desarrollo de Nuevas Nanoformulaciones Terapéuticas Multifuncionales
- Development of In Vitro Cultures for Investigating Pain Mechanisms: Studying Ion Channels Alterations and Sex Differences in a Paclitaxel-Induced CIPN Model
- Diferenciación directa de fibroblastos humanos a neuronas sensoriales
- Digitalización del material de laboratorio mediante etiquetado de códigos QR
- Direct conversion of human fibroblasts to sensory neurons
- Direct conversion of human fibroblasts to sensory neurons
- Diseño de un biosensor fluorescente basado en polímeros conjugados para el cribado de nuevos antidiabéticos
- Diseño de un nanosensor fluorescente para el cribado de nuevos fármacos antidiabéticos
- Efecto citotóxico y citostático de una mezcla de flavonas en modelos celulares de cáncer de mama.
- Efectos del envejecimiento sobre la función de la célula ß pancreática y la sensibilidad a la insulina.
- Effects of aging on pancreatic alpha and beta-cells: interplay with peripheral insulin sensitivity.
- El programa TFGi: trabajos de fin de grado interdisciplinares en la UMH
- El programa TFGi: trabajos de fin de grado interdisciplinares en la UMH
- Estudio preliminar del efecto de la cepa B longum sub infantis 16p1 sobre la colestasis en ratas con ligadura del conducto biliar
- Evaluación de los mecanismos moleculares que se establecen durante una crisis de migraña a nivel de SNP
- Exposure to bisphenol-A induces pancreatic beta cell apoptosis
- Extraction effect on the bioactive potential from persimmon (Diospyros kaki Thunb.) dietary fiber obtained from by-products
- FORMACIÓN EN COMPETENCIAS TRANSVERSALES PARA LA REALIZACIÓN DE TRABAJOS FIN DE GRADO INTERDISCIPLINARES
- FORMACIÓN EN COMPETENCIAS TRANSVERSALES PARA LA REALIZACIÓN DE TRABAJOS FIN DE GRADO INTERDISCIPLINARES
- FORMACIÓN EN COMPETENCIAS TRANSVERSALES PARA LA REALIZACIÓN DE TRABAJOS FIN DE GRADO INTERDISCIPLINARES
- Fibre-rich ingredients prepared from persimmon food by-products are potent prebiotics and antimicrobials
- Fluorescent polymeric nanoparticles for doxorubicin drug delivery and bioimaging
- Homo-FRET based monitoring of the bidirectional crosstalk during the gating of potassium channel KcsA
- IDENTIFICATION OF NOVEL THERAPEUTIC AGENTS IN FISH NUCLEATED RED BLOOD CELLS
- Identificación y Caracterización de nuevos moduladores de TRPM8.
- Identification and characterization of new TRPM8 modulators.
- Identification of new therapeutic targets for the treatment of type 1 diabetes based on the survival strategies of pancreatic alpha cells
- Identification of new therapeutic targets for the treatment of type 1 diabetes based on the survival strategies of pancreatic alpha-cells
- Improving Antiviral Responses in Fish: From Cell Target Search to Prophylactic Design and Administration
- Inflammatory bowel disease in immigrants to Spain: results of the EIIMIGRA study from GETECCU (ENEIDA registry)
- Influence of mycorrhization with Glomus sp. on pharmacologically active substances in the culture of Cistus albidus L. (Cistaceae)
- Influencia de la micorrización con Glomus ssp. sobre sustancias farmacológicamente activas en el cultivo de Cistus albidus L. (Cistaceae)
- Influencia de las propiedades del suelo en mostos de la variedad Monastrell en la Comarca del Noroeste-Región de Murcia
- Interacciones biológicas, una herramienta para encontrar nuevos sistemas de ¿drug delivery"
- Ion-Binding Features of the selectivity filter play a critical ron on K+ and Nak channels selectivity and inactivation process
- LA EXPOSICIÓN AL BISFENOL-A INDUCE LA APOPTOSIS DE LAS CÉLULAS ß PANCREÁTICAS
- Modelling Paclitaxel Induced-Neuropathic Pain: Ion Channels Alterations and Sex Differences
- Modulation of TRPV1 channels: from bench to bedside
- Optimización de la extracción de compuestos bioactivos a partir de subproductos de cultivos de alto interés agroalimentario.
- Optimización de la extracción de compuestos bioactivos presentes en subproductos agroalimentarios
- PIEU/2020/52: Trabajos Fin de Grado Interdisciplinares: Etapa de Consolidación,
- Pancreatic ß-cell viability tests aimed to identify diabetogenic chemicals
- Pancreatic ß-cell viability tests aimed to identify diabetogenic chemicals
- Quinnovalab: aumento de la autonomía del alumnado en el laboratorio de química mediante recursos digitales
- Realización de una práctica de química mediante escape room virtual
- Role of estrogen receptors ERa, ERb y GPER1 on pancreatic beta cell apoptosis
- Role of estrogen receptors on pancreatic beta cell survival under apoptotic stress
- SESSION 1
- Sensitizing effects of chemotherapeutic agents on sensory neurons: long-term culture studies
- Structural plasticity of the potassium channel KcsA pore helix and its link to the selectivity filter by Homo-FRET methodologies
- Studying an in vitro preclinical model of paclitaxel induced-neuropathy: Elucidating the role of NaV and KV ion channels
- TRPA1 plays a differential role in sex-biased sensitization of a mouse migraine model.
- The TRPM8 antagonist RGM8¿51 displays analgesic activity in different pain models.
- The effect of endocrine disruptor Bisphenol-A on ion channel regulation and its relationship with apoptosis in the human beta cell line EndoC-bH1
- The effect of the endocrine disruptor Bisphenol-A on ion channel regulation and its relationship with apoptosis in the human beta cell line EndoC-BH1
- The power of plants against superbugs
- Utilización de códigos QR para la digitalización del material de laboratorio
- Variaciones en el perfil polifenólico de extractos de Cistus albidus L. (Cistáceas) cultivadas bajo condiciones de estrés
- Venciendo la resistencia a los antibióticos mediante extractos vegetales, una estrategia prometedora.
- Zika and Dengue: Identification of new enzyme inhibitors combining computational and experimental strategies
- Zika and Dengue: Identification of new enzyme inhibitors combining computational and experimental strategies
- Zika and Dengue: Identification of new inhibitors combining computational and experimental strategies
- ¿Identificación y caracterización de nuevos moduladores del canal TRPM8
- ß¿Lactam TRPM8 antagonists with analgesic activity in different pain models
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event
- 12th REUNION ANUAL CIBERDEM 2021 (Congress Organization)
- 23rd EUROPEAN CONGRESS OS ENDOCRINOLOGY / ECE2021 (Congress Organization)
- 57TH EASD ANNUAL MEETING (Congress Organization)
- 7TH INTERNATIONAL IBERIAN BIOPHYSICS CONGRESS (Congress Organization)
- CICLO ENCUENTROS CON INVESTIGADORES: INVESTIGACION Y LONGEVIDAD: BUSCANDO RESPUESTAS POSITIVAS PARA VIDAS LONGEVAS (Congress Organization)
- I JORNADA DE JOVENES INVESTIGADORES DEL IDIBE (Congress Organization)
- INTERNATIONAL WORKSHOP ON CHRONIC PAIN AND ITCH: MECHANISMS AND CIRCUITS (Congress Organization)
- XIII JORNADA DE SAN ALBERTO MAGNO (Congress Organization)
- XXXII CONGRESO DE LA SOCIEDAD ESPAÑOLA DE DIABETES (Congress Organization)
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external project
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hiring
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invited conference
- Current Topics in Biochemistry 2021 - Brazil
- Diabetes durante el embarazo: buscando las causas
- Disruptores Endocrinos
- Día internacional de la mujer y la niña en la ciencia
- Endocrine disruptors and type 2 diabetes: OBERON, an integrated approach for hazard identification
- Identification of new therapeutic targets for the treatment of type 1 diabetes based on the survival strategies of pancreatic alpha cells
- New hazard classes for endocrine disruptors in CLP
- XXXV Reunião Anual da FeSBE
- the role of scientists in influencing public decision and their interaction with policy makers
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operating licence
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patent
-
person
-
person (active)
- ALONSO MAGDALENA, PALOMA
- ALVAREZ MARTINEZ, FRANCISCO JAVIER
- BABILONI CHUST, IGNACIO
- BALLESTA PAYA, JUAN JOSE
- BARRAJON CATALAN, ENRIQUE
- BONET GARCIA, RAUL
- BONMATI BOTELLA, BEATRIZ
- BORONAT BELDA, TALIA
- CABAÑERO FERRI, DAVID
- CHICO GRAS, VERONICA
- DE ANDRES LOPEZ, JORGE
- DIAZ PUERTAS, ROCIO
- ENCINAR HIDALGO, JOSÉ ANTONIO
- ESQUEMBRE TOME, ROCIO
- ESTAÑ CEREZO, GABRIEL
- FALCO GRACIA, JUAN ALBERTO
- FERNANDEZ ESCAMILLA, ANA MARIA
- FERNÁNDEZ BALLESTER, GREGORIO JOAQUIN
- FERNÁNDEZ CARVAJAL, ASIA
- FERRER MONTIEL, ANTONIO VICENTE
- FUENTES MARHUENDA, ESTHER TERESA
- GIORGI , SIMONA
- GIUDICI BESSEGHINI, ANA MARCELA
- GOMEZ PEREZ, FRANCISCO JAVIER
- GONZALEZ NAVAJAS, JOSE MANUEL
- GONZALEZ ROS, JOSE MANUEL
- HERRANZ LOPEZ, MARIA DOLORES
- HORNOS ADAN, FELIPE
- LAMBERTI ., ANGELA
- LOSADA ECHEBERRIA, MARIA
- MALLAVIA MARIN, RICARDO
- MARROQUI ESCLAPEZ, LAURA
- MARTI BRUÑA, NURIA
- MARTINEZ GODFREY, JESICA
- MARTINEZ TOME, MARIA JOSE
- MATEO MARTÍNEZ, CARMEN REYES
- MEDINA GALI, REGLA MARIA
- MICOL MOLINA, VICENTE
- NADAL NAVAJAS, ANGEL
- NEIRA FALEIRO, JOSE LUIS
- OLIVARES VICENTE, MARIA DOLORES
- ORTEGA-VILLAIZAN ROMO, MARIA DEL MAR
- PEREZ GARCIA-ESTAÑ, LUIS
- PEREZ SERNA, ATENEA ALEXANDRA
- POMARES BRI, IRENE CONCEPCIÓN
- POVEDA LARROSA, JOSE ANTONIO
- QUESADA MOLL, IVAN
- RIPOLL ORTS, CRISTINA
- RUBIO CAMACHO, MARTA
- RUIZ TORRES, VERONICA
- SACEDA SANCHEZ, MIGUEL
- SALVADOR MIRA, MARIA ELIZABHET
- SAURA LOPEZ, DOMINGO
- SOUSA DOS SANTOS, REINALDO
- TORRES MONTERO, MARIA REMEDIOS
- VALERO ROCHE, MANUEL
- VILLALAIN BOULLON, JOSÉ
- VILLALBA RIQUELME, EVA MARIA
- ZAPATER HERNANDEZ, PEDRO
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proceedings
-
research project
- 2011/00006/002
- 2015/00364/001
- 2017/00381/001
- 2020/PSG/00006
- AICO/2020/026
- AORG/2021/120
- APE/2021/022
- APOTIP/2021/014
- BFU2017-86579-R
- COMPENDIA21/07
- CONCEPTO21/03
- CTM2017-88978-R
- DIFUNDE21/05
- EQC2018-004372-P
- EUR2020-112098
- FCT-20-16204
- IDIFEDER/2020/022
- IDIFEDER/2021/036
- ILISABIO/2020/A09
- ILISABIO/2020/A31
- INNTA1/2021/11
- JJ0031IP
- MAT2017-86805-R
- PGC2018-093505-B-I00
- PIEU/2020/41
- PIEU/2020/52
- PRODICUMH2021_17
- PROMETEO/2020/006
- PROYECTA21/03
- RED2018-102628-T
- RTC-2017-6507-1
- RTI2018-096724-B-C21
- RTI2018-096957-B-C22
- RTI2018-097189-B-C21
- RTI2018-101969-J-I00
- SEJI/2018/023
- VIDIF21/42
- VIDIF21/62
- VIDIF21/85
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technological support
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thesis
- COMBINACIÓN DE UNA TERAPIA ENZIMÁTICA CON NANOTECNOLOGÍA PARA EL TRATAMIENTO DEL CÁNCER
- COMPUESTOS ANTIMICROBIANOS DE ORIGEN NATURAL: UNA OPORTUNIDAD PARA EL TRATAMIENTO DE ENFERMEDADES INFECCIOSAS RESISTENTES A ANTOBIÓTICOS
- CRIBADO DE EXTRACTOS NATURALES A PARTIR DE SUBPRODUCTOS DE LA INDUSTRIA FRUTÍCOLA PARA LA OBTENCIÓN DE NUEVOS PRINCIPIOS ACTIVOS CON FINES DERMOCOSMÉTICOS
- DESIGN AND FUNCTIONAL VALIDATION OF PAIN MODULATORS: CROSSTALK BETWEEN TRAAK AND TRPV1
- Descubrimiento de nuevos moduladores de TRPM8 y su potencial terapéutico
- INVOLVEMENT OF TRANSIENT RECEPTOR POTENTIAL CHANNELS IN THE SEXUAL DIMORPHISM OF A MOUSE MODEL OF CHRONIC MIGRAINE
- PAPEL DEL RECEPTOR DE ESTRÓGENOS ß EN LOS EFECTOS DE LA EXPOSICIÓN PRENATAL AL BISFENOL-A EN LA CÉLULA ß PANCREÁTICA
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thrid party project