selected publications
-
academic article
- Gut microbial metabolic signatures in diabetes mellitus and potential preventive and therapeutic applications. GUT MICROBES. 240165-240185. 2024
- BCL-XL Overexpression Protects Pancreatic ß-Cells against Cytokine- and Palmitate-Induced Apoptosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 5657. 2023
- Celula alfa en diabetes tipo 1. SOCIEDAD ESPAÑOLA DE BIOQUIMICA Y BIOLOGIA MOLECULAR. 1-2. 2023
- Deucravacitinib, a tyrosine kinase 2 pseudokinase inhibitor, protects human EndoC-ßH1 ß-cells against proinflammatory insults. FRONTIERS IN IMMUNOLOGY. 126392-126393. 2023
- Screening of Metabolism-Disrupting Chemicals on Pancreatic Alpha-Cells Using In Vitro Methods. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 231. 2023
- G protein-coupled estrogen receptor activation by bisphenol-A disrupts the protection from apoptosis conferred by the estrogen receptors ER¿ and ERß in pancreatic beta cells. ENVIRONMENT INTERNATIONAL. 107250-107262. 2022
- In Vitro Assays to Identify Metabolism-Disrupting Chemicals with Diabetogenic Activity in a Human Pancreatic ß-Cell Model. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 5040-5058. 2022
- Bisphenol-S and Bisphenol-F alter mouse pancreatic ß-cell ion channel expression and activity and insulin release through an estrogen receptor ERß mediated pathway. CHEMOSPHERE. 1-14. 2020
- Oestrogen receptor ß mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells. DIABETOLOGIA. 1667-1680. 2019
- Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes. SCIENTIFIC REPORTS. 1-12. 2019
- DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway. DIABETOLOGIA. 1-14. 2018
- IFN-alpha induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells.. DIABETOLOGIA. 636-640. 2018
- Mitochondria as target of endocrine-disrupting chemicals: implications for type 2 diabetes. JOURNAL OF ENDOCRINOLOGY. 27-45. 2018
- PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-¿ and-¿ via IRF1 induction.. EBIOMEDICINE. 367-373. 2018
- Timing of Exposure and Bisphenol-A: Implications for Diabetes Development. FRONTIERS IN ENDOCRINOLOGY. 1-10. 2018
-
chapter
- Type I interferons as key players in pancreatic ß-cell dysfunction in type 1 diabetes. International Review of Cell and Molecular Biology. 1-80. 2021
-
congress communication
- Exploring Novel Approaches to Mitigate Early Type 1 Diabetes Inflammation: Small Molecule Inhibitors Targeting TYK2 and IFNAR1 Protein-Protein Interaction 2024
- Interacción entre infecciones virales y disruptores endocrinos en células ß 2024
- LA EXPOSICIÓN A IFNA AFECTA NEGATIVAMENTE A LA SEÑAL DE CA2+ INTRACELULAR Y A LA SECRECIÓN HORMONAL EN CÉLULAS ALFA Y BETA PANCREÁTICAS 2024
- PEQUEÑAS MOLÉCULAS INHIBIDORAS DE LA INTERACCIÓN PROTEÍNA-PROTEÍNA ENTRE TYK2 E IFNAR1 COMO UNA NUEVA ESTRATEGIA PARA LA PREVENCIÓN DE LA INFLAMACIÓN EN LOS ESTADIOS INICIALES DE LA DIABETES TIPO 1 2024
- TYK2 and IFNAR1 protein-protein interaction as a novel approach to prevent inflammation in early type 1 diabetes 2024
- The type 1 diabetes candidate gene EBI2 modulates virus-induced ¿¿-cell dysfunction via regulation of the IRF7 pathway 2024
- BISPHENOL-A IMPAIRS INSULIN INDUCED GLUCOSE UPTAKE AND HEXOKINASE II ACTIVITY IN DIFFERENTIATED L6 MYOTUBES 2023
- DESARROLLO Y OPTIMIZACIÓN DE UN INHIBIDOR PEPTÍDICO PARA EL TRATAMIENTO PREVENTIVO DE LA DIABETES TIPO 1 2023
- DEUCRAVACITINIB, UN INHIBIDOR DEL DOMINIO PSEUDOQUINASA DE LA TIROSINA QUINASA 2 (TYK2), PROTEGE A LAS CÉLULAS BETA HUMANAS FRENTE A AGRESIONES PROINFLAMATORIAS 2023
- Deucravacitinib, a tyrosine kinase 2 pseudokinase inhibitor, protects human ß c ells against proinflammatory insults 2023
- IFN¿ exposure affects Ca2+ signaling and hormone secretion in pancreatic alpha- and beta-cells 2023
- Screening of metabolism disrupting chemicals diabetogenic activity on pancreatic ¿ and ß cells using in vitro methods 2023
- Screening of metabolism-disrupting chemicals diabetogenic activity on pancreatic ¿- and ß-cells using in vitro methods 2023
- Screening of metabolism-disrupting chemicals on pancreatic ß-Cells 2023
- Small-molecule inhibitors of protein-protein interaction between TYK2 and IFNAR1 as a new strategy to prevent inflammation in early type 1 diabetes 2023
- Small-molecule inhibitors of protein-protein interaction between TYK2 and IFNAR1 as a new strategy to prevent inflammation in early type 1 diabetes 2023
- Assessment of pancreatic ß-cell function as a tool to identify diabetogenic chemicals 2022
- Evaluación de inhibidores de la vía de interferón como nuevas terapias para la diabetes tipo 1 2022
- G protein-coupled estrogen receptor activation by Bisphenol-A disrupts protection from apoptosis conferred by estrogen receptors ER¿ and ERß in pancreatic beta cells 2022
- GRUPO EXPERIMENTACIÓN BÁSICA EN DIABETES DE LA SED: Vimentin as a regulator of cell survival and endoplasmic reticulum stress in pancreatic ¿- and ß-cells 2022
- IDENTIFICACIÓN DE NUEVAS DIANAS TERAPÉUTICAS PARA EL TRATAMIENTO DE LA DIABETES TIPO 1 BASADAS EN LAS ESTRATEGIAS DE SUPERVIVENCIA DE LAS CÉLULAS ALFA PANCREÁTICAS 2022
- In vitro assays to identify metabolism-disrupting chemicals with diabetogenic activity in a mouse pancreatic alpha-cell model 2022
- LA SOBREEXPRESIÓN DE BCL-XL COMO ESTRATEGIA PARA PROTEGER A LAS CÉLULAS BETA PANCREÁTICAS DE LA APOPTOSIS INDUCIDA POR CITOQUINAS PROINFLAMATORIAS EN LA DIABETES TIPO 1 2022
- Papel de los receptores de estrógenos en la apoptosis de la célula ß pancreática 2022
- Vimentin as a regulator of cell survival and endoplasmic reticulum stress in pancreatic alpha and beta cells. 1-469. 2022
- Vimentin as a regulator of cell survival and endoplasmic reticulum stress in pancreatic alpha- and beta-cells 2022
- BPA requires ERalpha, ERbeta, and GPER to induce apoptosis in the rat ß-cell line INS-1E 2021
- Exposure to bisphenol-A induces pancreatic beta cell apoptosis. 1-380. 2021
- Identification of new therapeutic targets for the treatment of type 1 diabetes based on the survival strategies of pancreatic alpha cells. 1-380. 2021
- Identification of new therapeutic targets for the treatment of type 1 diabetes based on the survival strategies of pancreatic alpha-cells 2021
- LA EXPOSICIÓN AL BISFENOL-A INDUCE LA APOPTOSIS DE LAS CÉLULAS ß PANCREÁTICAS 2021
- Pancreatic ß-cell viability tests aimed to identify diabetogenic chemicals 2021
- Pancreatic ß-cell viability tests aimed to identify diabetogenic chemicals 2021
- Role of estrogen receptors ERa, ERb y GPER1 on pancreatic beta cell apoptosis 2021
- Role of estrogen receptors on pancreatic beta cell survival under apoptotic stress 2021
- The effect of the endocrine disruptor Bisphenol-A on ion channel regulation and its relationship with apoptosis in the human beta cell line EndoC-BH1 2021
- BCL-XL, PERO NO EL COMPLEMENTO C3, PROTEGE A LAS CÉLULAS ALFA CONTRA EL ESTRÉS METABÓLICO O LA APOPTOSIS INDUCIDA POR INFLAMACIÓN 2020
- Efecto de la sobreexpresión de BCL-XL en la función y supervivencia de la célula ß pancreática. 2020
- Papel de ERalpha, ERbeta y GPR30 en la apoptosis en la línea de célula ß INS-1E 2020
- Role of ERalpha, ERbeta and GPER1 on INS-1E ß-cell line apoptosis 2020
- BCL-XL, but not complement C3, protect alpha-cells against metabolic stress- or proinflammatory-induced apoptosis 2019
- BCL-XL, but not complement C3, protects alpha-cells against metabolic stress- or proinflammatory-induced apoptosis 2019
- BISPHENOL-A MODULATES ION CHANNEL EXPRESSION AND FUNCTION VIA ESTROGEN RECEPTOR ¿ IN MOUSE PANCREATIC BETA CELLS 2019
- Bisphenol-A modulates ion channel expression and activity in mouse pancreatic beta cell via oestrogen receptor beta (ERbeta) 2019
- Differential effects of chronic exposure to bisphenol A on ion channel activity and expression in mouse pancreatic ß-cells 2019
- Exposure to bisphenol-A induces pancreatic ß-cell apoptosis 2019
- Interfering with beta-cells or: how type I interferons are implicated in type 1 diabetes 2019
- Interfering with ß-cells or: how type I interferons are implicated in type 1 diabetes 2019
- xBCL-XL, but not complement C3, protects alpha cells against metabolic stress- or proinflammatory-induced apoptosis 2019