PEREZ GARCIA-ESTAÑ, LUIS

Person (Active)

Positions

Profesor/a Titular Universidad, Bioquímica y Biología Molecular 2009 -
PDI INVESTIGADOR, Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2018 -
MIEMBRO, ESTRATEGIAS ANTIVIRALES 2012 -
PDI INVESTIGADOR, Instituto de Biología Molecular y Celular 2004 - 2018
Profesor/a Titular Escuela Universitaria, Bioquímica y Biología Molecular 2007 - 2009
Profesor Titular Escuela Universitaria, Bioquímica y Biología Molecular 2003 - 2007
Profesor Interino Titular E.U., Bioquímica y Biología Molecular 2002 - 2003
Ayudante de Universidad, Bioquímica y Biología Molecular 2000 - 2002
Ayudante de Universidad, DPTO. NEUROQUIMICA 1997 - 2000

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supported publications or other works

selected publications

academic article
- Fish Innate Immune Response to Viral Infection¿An Overview of Five Major Antiviral Genes. VIRUSES-BASEL. 1546-1559. 2022
- How modular protein nanoparticles may expand the ability of subunit anti-viral vaccines: The spring viremia carp virus (SVCV) case. FISH & SHELLFISH IMMUNOLOGY. 1051-1062. 2022
- Antiviral Function of NKEF against VHSV in Rainbow Trout. BIOLOGY-BASEL. 2021
- Immunomodulatory Lectin-like Peptides for Fish Erythrocytes-Targeting as Potential Antiviral Drug Delivery Platforms. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021
- Grupo de Innovación Docente en el Grado de Biotecnología. SEM@FORO . 32-33. 2020
- Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol -. SCIENTIFIC REPORTS. 1-18. 2020
- Acute phase protein response to viral infection and vaccination. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 196-202. 2019
- Hydroxycholesterol binds and enhances the anti-viral activities of zebrafish monomeric c-reactive protein isoforms. PLOS ONE. 1-23. 2019
- IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells.. FRONTIERS IN IMMUNOLOGY. 1-15. 2019
- Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets. VACCINES. 1-23. 2019
- Plasma proteomic analysis of zebrafish following spring viremia of carp virus infection. FISH & SHELLFISH IMMUNOLOGY. 892-899. 2019
- Potential Role of Rainbow Trout Erythrocytes as Mediators in the Immune Response Induced by a DNA Vaccine in Fish.. VACCINES. 1-22. 2019
- Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers.. CELLS. 1-29. 2019
- Viral interference between infectious pancreatic necrosis virus and spring viremia of carp virus in zebrafish. AQUACULTURE. 370-377. 2019
- Beta-glucan enhances the response to SVCV infection in zebrafish. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 307-314. 2018
- Chromatin immunoprecipitation and high throughput sequencing of SVCV-infected zebrafish reveals novel epigenetic histone methylation patterns involved in antiviral immune response. FISH & SHELLFISH IMMUNOLOGY. 514-521. 2018
- Turbot (Scophthalmus maximus) Nk-lysin induces protection against the pathogenic parasite Philasterides dicentrarchi via membrane disruption. FISH & SHELLFISH IMMUNOLOGY. 190-199. 2018
- Identification of diverse defense mechanisms in trout red blood cells in response to VHSV halted viral replication. F1000RESEARCH. 2017
- Infectious pancreatic necrosis virus triggers antiviral immune response in rainbow trout red blood cells, despite not being infective. F1000RESEARCH. 2017
- Neutralization of viral infectivity by zebrafish c-reactive protein isoforms. MOLECULAR IMMUNOLOGY. 145-155. 2017
- Protective immunity against Megalocyticivirus infection in rock bream (Oplegnatus fasciatus) following CpG ODN administration. VACCINE. 3691-3699. 2017
- Induction of viral interference by IPNV-carrier cells on target cells: a cell co-culture study. FISH & SHELLFISH IMMUNOLOGY. 483-489. 2016
- Restricted replication of viral hemorrhagic septicaemia virus (VHSV) in a birnavirus-carrier cell culture . ARCHIVES OF VIROLOGY. 1-5. 2016
- Structure and functionalities of the human c-reactive protein compared to the zebrafish multigene family of c-reactive-like proteins. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 33-40. 2016
- Vacunas para ¿virus de peces?. VIROLOGIA . 12-13. 2016
- Autophagy-inducing peptides from mammalian VSV and fish VHSV rhabdoviral G glycoproteins (G) as models for the development of new therapeutic molecules. AUTOPHAGY. 1666-1680. 2014
- In addition to its antiviral and immunomodulatory properties, the zebrafish ß-defensin 2 (zfBD2) is a potent viral DNA vaccine molecular adjuvant. . ANTIVIRAL RESEARCH. 136-147. 2014
- Antiviral activity produced by an IPNV-carrier EPC cell culture confers resistance to VHSV infection. VETERINARY MICROBIOLOGY. 412-418. 2013
- Increasing Versatility of the DNA Vaccines through Modification of the Subcellular Location of Plasmid-Encoded Antigen Expression in the In Vivo Transfected Cells. PLOS ONE. 1-12. 2013
- Ex vivo transfection of trout pronephros leukocytes, a model for cell culture screening of fish DNA vaccine candidates.. VACCINE. 5983-5990. 2012
- Characterization of an infectious pancreatic necrosis (IPN) virus carrier cell culture with resistance to superinfection with heterologous viruses. VETERINARY MICROBIOLOGY. 48-55. 2011
- In vitro analysis of the factors contributing to the antiviral state induced by a plasmid encoding the viral haemorrhagic septicaemia virus glycoprotein G in transfected trout cells. VACCINE. 737-743. 2011
- Pepscan mapping of Viral Haemorrhagic Septicaemia virus (VHSV) glycoprotein G major lineal determinants implicated in triggering host cell antiviral responses mediated by type I IFN. JOURNAL OF VIROLOGY. 1234-1240. 2010
- Antimicrobial Peptides as Model Molecules for the Development of Novel antiviral agents in aquaculture . MINI-REVIEWS IN MEDICINAL CHEMISTRY. 1159-1164. 2009
- The immunogenicity of viral haemorragic septicaemia rhabdovirus (VHSV) DNA vaccines can depend on plasmid regulatory sequences. VACCINE. 1938-1948. 2009
- The rainbow trout TLR9 gene and its role in the immune responses elicited by a plasmid encoding the glycoprotein G of the viral haemorrhagic septicaemia rhabdovirus (VHSV).. MOLECULAR IMMUNOLOGY. 1710-1717. 2009
- Expression and antiviral activity of a ß-defensin-like peptide identified in the rainbow trout (Oncorhynchus mykiss) EST sequences. MOLECULAR IMMUNOLOGY. 757-765. 2008
- In vivo modulation of the rainbow trout (Oncorhynchus mykiss) immune response by the human alpha defensin-1, HNP1. FISH & SHELLFISH IMMUNOLOGY. 102-112. 2008
- Inhibitory effect of mycophenolic acid on the replication of infectious pancreatic necrosis virus and viral hemorrhagic septicemia virus.. ANTIVIRAL RESEARCH. 332-338. 2008
- Assessment of the inhibitory effect of ribavirin on the rainbow trout rhabdovirus VHSV by real-time reverse-transcription PCR. . VETERINARY MICROBIOLOGY. 52-60. 2007
- Dual antiviral activity of human alpha-defensin-1 against viral haemorrhagic septicaemia rhabdovirus (VHSV): inactivation of virus particles and induction of a type I interferon-related response. . ANTIVIRAL RESEARCH. 111-123. 2007
- In vitro and in vivo differential expression of rainbow trout (Oncorhynchus mykiss) Mx isoforms in response to viral haemorrhagic septicaemia virus (VHSV) G gene, poly I:C and VHSV. . FISH & SHELLFISH IMMUNOLOGY. 210-221. 2007
- Identification of selective inhibitors of VHSV from biased combinatorial libraries of N,N¿-disubstituted 2,5- piperazinediones. ANTIVIRAL RESEARCH. 107-115. 2006
- Rapid detection and quantitation of viral hemorrhagic septicemia virus in experimentally challenged rainbow trout by real-time RT-PCR.. JOURNAL OF VIROLOGICAL METHODS. 154-159. 2006
- Stable expression of bioactive recombinant pleurocidin. in a fish cell line. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 1217-1228. 2006
- Rapid detection and quantitation of viral hemorrhagic septicemia virus in experimentally challenged rainbow trout by real-time RT-PCR. JOURNAL OF VIROLOGICAL METHODS. 154-159. 2005
- The olive leaf extract exhibits antiviral activity against viral haemorhagic septicaemia virus (VHSV). ANTIVIRAL RESEARCH. 129-136. 2005
- Reversible inhibition of spreading of in vitro infection and imbalance of viral protein accumulation at low pH in VHSV, a salmonid rhabdovirus. JOURNAL OF VIROLOGY. 1936-1944. 2004
- Antibody response to a linear epitope of the protein G of a rhabdovirus in immunized trout.. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY. 89-99. 2002
- A protein G fragment from the salmonid VHS rhabdovirus induces cell-to-cell fusion and membrane phosphatidylserine translocation at low pH?. JOURNAL OF BIOLOGICAL CHEMISTRY. 46268-46275. 2001
book
- Manual didáctico de virología. EDITORIAL ELECTRONICA DE LA UMH. 2021
chapter
- A Cell Membrane Fusion Assay for the Fish Pathogen Spring Viremia of Carp Virus (SVCV). Virus-Host Interactions. 49-56. 2023
- Evaluation of the degree of student satisfaction. VI Simposio Internacional de Innovación Aplicada. 42-43. 2019
- Implementation of new teaching innovation tools in the biotechnology degree from the UMH: Evaluation of the degree of impact on academic perfomance. VI Simposio Internacional de Innovación Aplicada. 48-49. 2019
congress communication
patent
- PÉPTIDOS ACTIVADORES DE LA INFECTIVIDAD DEL RHABDOVIRUS DE LA SEPTICEMIA HEMORRÁGICA VÍRICA (VHSV)

presentations

invited conference
- LA GRIPE AVIAR:¿EL ENEMIGO A LAS PUERTAS¿; CICLO DE CONFERENCIAS CIENCIAS DE LA VIDACLUB ROTARYS DE ELCHE , Conferencia 2005

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PEREZ GARCIA-ESTAÑ, LUIS

Positions

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supported publications or other works

selected publications

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