Publicaciones en VIVO

Mapa de la ciencia

Red de Coinvestigador

VILLALAIN BOULLON, JOSÉ

Person (Active)

Positions

Catedrático/a de Universidad, Bioquímica y Biología Molecular 2007 -
PDI INVESTIGADOR, Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2018 -
MIEMBRO, ESTRATEGIAS ANTIVIRALES 2012 -
PDI INVESTIGADOR, Instituto de Biología Molecular y Celular 2004 - 2018
Catedrático de Universidad, Bioquímica y Biología Molecular 2003 - 2007
Profesor Titular Universidad, Bioquímica y Biología Molecular 2000 - 2003
Profesor Titular Universidad, DPTO. NEUROQUIMICA 1997 - 2000

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supported publications or other works

selected publications

academic article
- Bergamottin: location, aggregation and interaction with the plasma membrane. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 1-12. 2023
- Labyrinthopeptin A2 disrupts raft domains. CHEMISTRY AND PHYSICS OF LIPIDS. 105303-105311. 2023
- Phospholipid binding of the dengue virus envelope E protein segment containing the conserved His residue. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 184198-184209. 2023
- SARS-CoV-2 Protein S Fusion Peptide Is Capable of Wrapping Negatively-Charged Phospholipids. MEMBRANES. 344-364. 2023
- Envelope E protein of dengue virus and phospholipid binding to the late endosomal membrane. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 183889-183898. 2022
- Interaction of Lassa virus fusion and membrane proximal peptides with late endosomal membranes. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 184031-184042. 2022
- Procyanidin C1 Location, Interaction, and Aggregation in Two Complex Biomembranes. MEMBRANES. 692-708. 2022
- Aggregation of 25-hydroxycholesterol in a complex biomembrane. Differences with cholesterol. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 183413. 2020
- Identification of the phospholipid binding regions of the envelope E protein of flaviviruses by molecular dynamics.. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 5136-5147. 2020
- Location, Orientation and Aggregation of Bardoxolone-ME, CDDO-ME, in a Complex Phospholipid Bilayer Membrane. JOURNAL OF MEMBRANE BIOLOGY. 115-128. 2020
- Epigallocatechin-3-gallate location and interaction with late endosomal and plasma membrane model membranes by molecular dynamics.. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 3122-3144. 2019
- Epigallocatechin-3-gallate location and interaction with late endosomal and plasma membrane model membranes by molecular dynamics. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 1-13. 2018
- Spontaneous membrane insertion of a dengue virus NS2A peptide. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 56-66. 2017
- Location of the bioactive pentacyclic triterpene ursolic acid in the membrane. A molecular dynamics study. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 1-13. 2016
- Molecular Dynamics Study of the Membrane Interaction of a Membranotropic Dengue Virus C Protein Derived Peptide. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 1-12. 2016
- The Location of the Protonated and Unprotonated Forms of Arbidol in the Membrane: A Molecular Dynamics Study. JOURNAL OF MEMBRANE BIOLOGY. 381-391. 2016
- Oleuropein aglycone in lipid bilayer membranes. A molecular dynamics study. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2849-2858. 2015
- Membrane interacting regions of Dengue virus NS2A protein. JOURNAL OF PHYSICAL CHEMISTRY B. 10142-10155. 2014
- Membranotropic regions of the dengue virus prM protein. BIOCHEMISTRY. 5280-5289. 2014
- Possible mechanism of structural transformations induced by StAsp-PSI in lipid membranes. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 339-347. 2014
- Electrostatically Driven Lipid-Lysozyme Mixed Fibers Display a Multilamellar Structure without Amyloid Features . SOFT MATTER. 0-13. 2013
- Hydrophobic segment of dengue virus C protein. Interaction with model membranes.. MOLECULAR MEMBRANE BIOLOGY. 273-287. 2013
- N-terminal AH2 segment of protein NS4B from hepatitis C virus. Binding to and interaction with model biomembranes.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1938-1952. 2013
- Possible mechanism of structural transformations induced by StAsp-PSI in lipid membranes.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 339-347. 2013
- Interaction with membranes of the full c-terminal domain of protein NS4B from Hepatitis C virus. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2536-2549. 2012
- NS4A AND NS4B proteins from dengue virus: Membranotropic regions. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2818-2830. 2012
- The membrane spanning domains of protein NS4B from Hepatitis C virus. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2958-2966. 2012
- Cholesterol and membrane phospholipid compositions modulate the leakage capacity of the swaposin domain from a potato aspartic protease (StAsp-PSI). BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. 1038-1044. 2011
- Membrane interaction of segment H1 (NS4B(H1)) from hepatitis C virus non-structural protein 4B. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1219-1229. 2011
- Secondary structure determination by FTIR of an archaeal ubiquitin-like polypeptide from Natrialba magadii. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 1101-1107. 2011
- The membrane-active regions of the dengue virus proteins C and E. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2390-2402. 2011
- A membranotropic region in the C-terminal domain of hepatitis C virus protein NS4B interaction with membranes. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 327-337. 2010
- Interaction of the N-terminal segment of HCV protein NS5A with model membranes.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1212-1224. 2010
- Membrane fluidity determines sensitivity of filamentous fungi to chitosan.. MOLECULAR MICROBIOLOGY. 1021-1032. 2010
- Membranotropic effects of arbidol, a broad anti-viral molecule, on phospholipid model membranes.. JOURNAL OF PHYSICAL CHEMISTRY B. 8544-8554. 2010
- A membranotropic region in the C-terminal domain of Hepatitis C virus protein NS4B Interaction with membranes.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 909-999. 2009
- Biophysical characterization of the fusogenic region of HCV envelope glycoprotein E1.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2183-2193. 2009
- Interaction of a peptide corresponding to the loop domain of the S2 SARS-CoV virus protein with model membranes.. MOLECULAR MEMBRANE BIOLOGY. 236-248. 2009
- Screening a peptide library by DSC and SAXD: comparison with the biological function of the parent proteins.. PLOS ONE. 4356. 2009
- A second SARS-CoV S2 glycoprotein internal membrane-active peptide. Biophysical characterization and membrane interaction. BIOCHEMISTRY. 8214-8224. 2008
- Biophysical characterization and membrane interaction of the most membranotropic region of the HIV-1 gp41 endodomain. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1298-1307. 2008
- Hepatitis C virus core protein binding to lipid membranes: the role of domains 1 and 2. JOURNAL OF VIRAL HEPATITIS. 346-356. 2008
- Identification of the membrane-active regions of hepatitis C virus p7 protein: biophysical characterization of the loop region. JOURNAL OF BIOLOGICAL CHEMISTRY. 8089-8101. 2008
- Interaction of the most membranotropic region of the HCV E2 envelope glycoprotein with membranes. Biophysical characterization. BIOPHYSICAL JOURNAL. 4737-4750. 2008
- Membrane insertion of the three main membranotropic sequences from SARS-CoV S2 glycoprotein. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2765-2774. 2008
- Structural and dynamic characterization of the interaction of the putative fusion peptide of the S2 SARS-CoV virus protein with lipid membranes. JOURNAL OF PHYSICAL CHEMISTRY B. 6997-7007. 2008
- The pre-transmembrane region of the HCV E1 envelope glycoprotein Interaction with model membranes. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2069-2080. 2008
- Characterization of the interaction of two peptides from the N terminus of the NHR domain of HIV-1 gp41 with phospholipid membranes. BIOCHEMISTRY. 10572-10584. 2007
- Interaction of a Peptide from the Pre-transmembrane Domain of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein with Phospholipid Membranes. JOURNAL OF PHYSICAL CHEMISTRY B. 13714-13725. 2007
- Role of membranes on the antibacterial and anti-inflammatory activities of the bioactive compounds from Hypoxis rooperi corm extract. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 119-131. 2007
- Structure of the C-terminal domain of the pro-apoptotic protein Hrk and its interaction with model membranes. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1659-1670. 2007
- Two-dimensional infrared correlation spectroscopy study of the interaction of oxidized and reduced cytochrome c with phospholipid model membranes. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2409-2420. 2007
- Antifungal effects and mechanism of action of viscotoxin A3. EUROPEAN JOURNAL OF BIOCHEMISTRY. 72-83. 2006
- Rosemary (Rosmarinus officinalis) diterpenes affect lipid polymorphism and fluidity in phospholipid membranes. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 224-236. 2006
- The membrane-active regions of the HCV E1 and E2 envelope glycoproteins. BIOCHEMISTRY. 3755-3768. 2006
- The membranotropic regions of the endo and ectodomains of the HIV gp41 envelope glycoprotein. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 111-123. 2006
- A peptide pertaining to the loop segment of human immunodeficiency virus gp41 binds and interacts with model biomembranes: implications for the fusion mechanism.. JOURNAL OF VIROLOGY. 5142-5152. 2005
- Identification of the membrane-active regions of the severe acute respiratory syndrome coronavirus spike membrane glycoprotein using a 16/18-mer peptide scan: implications for the viral fusion mechanism.. JOURNAL OF VIROLOGY. 1743-1752. 2005
- Interaction of a Peptide Derived from the N-Heptad Repeat Region of gp41 Env Ectodomain with Model Membranes. Modulation of Phospholipid Phase Behavior. . BIOCHEMISTRY. 14275-14288. 2005
- The cytotoxic properties of a plant lipid transfer protein involve membrane permeabilization of target cells. . LETTERS IN APPLIED MICROBIOLOGY. 183-189. 2005
- Identification of membrane-active regions of the HIV-1 envelope glycoprotein gp41 using a 15-mer gp41-peptide scan. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 97-105. 2004
- Location and orientation of Triclosan in phospholipid model membranes. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 448-453. 2004
- Mistletoe viscotoxins induce membrane permeabilization and spore death in phytopathogenic fungi. PHYSIOLOGIA PLANTARUM. 2-7. 2004
- Interaction of viscotoxins A3 and B with membrane model systems. implications to their mechanism of action. BIOPHYSICAL JOURNAL. 971-981. 2003
- The relationship between the antioxidant and the antibacterial properties of galloylated catechins and the structure of phospholipid model membranes. FREE RADICAL BIOLOGY AND MEDICINE. 648-662. 2003
- A MAS-NMR study of the location of (+)-totarol, a diterpenoid bioactive molecule, in phospholipid model membranes.. CHEMISTRY AND PHYSICS OF LIPIDS. 33-39. 2002
- Interaction and structural alterations of the peptide hormone a-MSH in the presence of binaru phospholipid membranes.. BIOPHYSICAL JOURNAL. 2273-2283. 2001
- Membranotropic effects of the antibacterial agent triclosan.. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 128-136. 2001
- Structure and interaction with membrane model systems of a peptide derived from the major epitope region of HIV protein gp41. Implications on viral fusion mechanism.. BIOCHEMISTRY. 3196-3207. 2001
chapter
- Membranotropic Regions of Membrane-Fusion Proteins: The Use of Peptide Libraries. Membrane-Active Peptides: Methods and Results on Structure and Function. 473-498. 2009
- Membrane activity of viscotoxins A3 and B. Interactions with model membrana systems. Fortschritte in del Misteltherapie. Aktueller Stand der Forschung und klinische Anwendung - Membrane activity of viscotoxins A3 and B. Interactions with model membrana systems. 99-108. 2005
- La Bioquímica y la Biología Molecular en la red,. Boletín no. 128 de la SEBBM.. 2000
congress communication

presentations

invited conference
- Paradigm of a viral membrane protein. NS4B from HCV, Conferencia 2011
- Membrane-active peptides from membrane-fusion proteins, Conferencia 2007
- The membrane-active regions of the HIV gp41 env glycoprotein full sequence, Conferencia 2006
- TEACHING RESEARCH: HYPERMEDIA, BIOCHEMISTRY AND THE 21st CENTURY- VIth European Symposium of The Protein Society, Conferencia 2005
- Hypermedia, Biochemistry And The 21st Century, Conferencia 2004
- Inhibitors of HIV gp41- mediated membrane fusion, Conferencia 2004
- Membrane fusion and gp41. How HIV enters the cell?., Conferencia 2003
- HYPERMEDIA AND BIOCHEMISTRY. THE NEXT STEP., Conferencia
- Interacción y localización de un péptido derivado de la región inmunodominante de la proteína gp41 del HIV en presencia de membranas modelo., Conferencia
- Uso de la espectrometría infrarroja bidimensional en el estudio de las interacciones moleculares proteína/membrana, Conferencia