Publicaciones en VIVO

Mapa de la ciencia

Red de Coinvestigador

FERRER MONTIEL, ANTONIO VICENTE

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Positions

Catedrático/a de Universidad, Bioquímica y Biología Molecular 2007 -
PDI INVESTIGADOR, Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2018 -
MIEMBRO, Moléculas bioactivas 2012 -
PDI INVESTIGADOR, Instituto de Biología Molecular y Celular 2004 - 2018
SUBDIRECTOR/A DE INSTITUTO, Instituto de Biología Molecular y Celular 2006 - 2011
Catedrático de Universidad, Bioquímica y Biología Molecular 2007
Profesor Titular Universidad, Bioquímica y Biología Molecular 2000 - 2007
SUBDIRECTOR/A DE CENTRO, Instituto de Biología Molecular y Celular 2005 - 2006
Profesor Titular Universidad, DPTO. NEUROQUIMICA 1999 - 2000
Profesor Interino Titular Unv., DPTO. NEUROQUIMICA 1997 - 1999

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selected publications

academic article
- The multicomponent Passerini reaction as a means of accessing diversity in structure, activity and properties: soft and hard vanilloid/cannabinoid modulators. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 11684. 2024
- Transplantation of dorsal root ganglia overexpressing the NaChBac sodium channel improves locomotion after complete SCI. MOLECULAR THERAPY. 1739-1759. 2024
- Benzydamine plays a role in limiting inflammatory pain induced by neuronal sensitization.. MOLECULAR PAIN. 1-12. 2023
- Compartmentalized primary cultures of dorsal root ganglion neurons to model peripheral pathophysiological conditions.. MOLECULAR PAIN. 1-11. 2023
- Compartmented primary cultures of dorsal root ganglion neurons to model peripheral pathophysiological conditions. MOLECULAR PAIN. 1-11. 2023
- Comprehensive survey of consensus docking for high-throughput virtual screening. MOLECULES. 175-204. 2023
- Design and validation of neuronal exocytosis blocking peptides as potential novel antiperspirants.. EXPERIMENTAL DERMATOLOGY. 999-1006. 2023
- First-in-Class Dual Hybrid Carbonic Anhydrase Inhibitors and Transient Receptor Potential Vanilloid 1 Agonists Revert Oxaliplatin-Induced Neuropathy.. JOURNAL OF MEDICINAL CHEMISTRY. 1616-1633. 2023
- Membrane Channels in Health and Diseases.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 1-2. 2023
- Progress in the structural basis of thermoTRP channel polymodal gating. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 743-763. 2023
- beta-Lactam TRPM8 Antagonists Derived from Phe-Phenylalaninol Conjugates: Structure-Activity Relationships and Antiallodynic Activity. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 14849-14871. 2023
- Androgenic TRPM8 1 activity drives sexual dimorphism in a murine model of chronic migraine.. NATURE COMMUNICATIONS. 6304-6321. 2022
- Paclitaxel in vitro reversibly sensitizes the excitability of IB4(-) and IB4(+) sensory neurons from male and female rats. BRITISH JOURNAL OF PHARMACOLOGY. 3693-3710. 2022
- TRPV1 in chronic pruritus and pain: Soft modulation as a therapeutic strategy. FRONTIERS IN MOLECULAR NEUROSCIENCE. 930964. 2022
- ThermoTRP channels in pain sexual dimorphism: new insights for drug intervention.. PHARMACOLOGY & THERAPEUTICS. 108297. 2022
- ¿Qué parte del cerebro me avisa del picor?. THE CONVERSATION. 1-3. 2022
- ß-Lactam TRPM8 antagonist RGM8-51 displays analgesic activity in different animal models. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2692-2716. 2022
- A capsaicinoid¿based soft drug, AG1529, for attenuating TRPV1¿mediated histaminergic and inflammatory sensory neuron excitability. SCIENTIFIC REPORTS. 246-256. 2021
- DD04107-Derived neuronal exocytosis inhibitor peptides: evidences for synaptotagmin-1 as a putative target.. BIOORGANIC CHEMISTRY. 23-28. 2021
- Phenylalanine-derived beta-Lactam TRPM8 modulators. Configuration effect on the antagonist activity. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2370-2392. 2021
- Structural and in vitro functional characterization of a menthyl TRPM8 antagonist indicates species-dependent regulation. ACS MEDICINAL CHEMISTRY LETTERS. 758-767. 2021
- A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration. JOURNAL OF MEDICINAL CHEMISTRY. 2372-2390. 2020
- Early stimulation of TREK channel transcription and activity induced by Oxaliplatin-dependent cytosolic acidification. . INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 164-167. 2020
- Highly functionalized ß-lactams and 2-ketopiperazines as TRPM8 antagonists with antitumor and antiallodynic activity.. SCIENTIFIC REPORTS. 14154-14165. 2020
- Improving a Natural Compound: Design of Innovative Neurocosmeceuticals for Sensitive Skin. IFSCC MAGAZINE. 37-44. 2020
- Investigational drugs in early phase clinical trials targeting thermotransient receptor potential (thermoTRP) channels. EXPERT OPINION ON INVESTIGATIONAL DRUGS. 1-14. 2020
- Moduladores del termorreceptor TRPV1 desactivables metabólicamente en la farmacología. ACTUALIDAD EN FARMACOLOGIA Y TERAPEUTICA. 162-172. 2020
- Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain.. ELIFE. 1-24. 2020
- Targeting thermoTRP ion channels: in silico preclinical approaches and opportunities. EXPERT OPINION ON THERAPEUTIC TARGETS. 1-19. 2020
- 1¿(2¿,5¿-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1- propanone (RGM079): A Positive Allosteric Modulator of ¿7 Nicotinic Receptors with Analgesic and Neuroprotective Activity. ACS CHEMICAL NEUROSCIENCE. 3900-3909. 2019
- A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration.. JOURNAL OF MEDICINAL CHEMISTRY. 1-12. 2019
- A positive allosteric modulator of alpha7 nicotinic receptors with analgesic and neuroprotective activity.. ACS CHEMICAL NEUROSCIENCE. 3900-3909. 2019
- Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 1-25. 2019
- Structure-based design of novel biphenyl amide antagonists of human Transient Receptor Potential Cation Channel Subfamily M Member 8 channels (TRPM8) with potential implications in the treatment of sensory neuropathies.. ACS CHEMICAL NEUROSCIENCE. 2100-2110. 2019
- The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3. FASEB J. 8263-8279. 2019
- Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of ¿7 nicotinic receptors with analgesic activity.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 157-165. 2018
- Effect of a novel TRPV1 antagonist on capsaicin nociceptors. FRONTIERS IN CELLULAR NEUROSCIENCE. 1-4. 2018
- Identification of a Potent Tryptophan-based TRPM8 Antagonist With in vivo Analgesic Activity. . JOURNAL OF MEDICINAL CHEMISTRY. 6140-6152. 2018
- Recent progress in non-opioid analgesic pepJdes.. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 36-52. 2018
- Targeting transient receptor potential vanilloid 1 channel (TRPV1) softly: the discovery of Passerini adducts as a topical treatment for inflammatory skin disorders. JOURNAL OF MEDICINAL CHEMISTRY. 4436-4455. 2018
- The Spanish Ion Channel Initative (SICI) Consortium: Ten Years (2008¿2018) of a Network of Excellence on Ion Channel Research.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 3514-3516. 2018
- Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of alpha 7 nicotinic receptors with analgesic activity. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 1-10. 2017
- Lipids as central modulators of sensory TRP channels.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1615-1628. 2017
- Sphingosine-1-Phosphate and the S1P3 Receptor Initiate Neuronal Retraction via RhoA/ROCK Associated with CRMP2 Phosphorylation. FRONTIERS IN MOLECULAR NEUROSCIENCE. 1-13. 2017
- Synthesis, high-throughput screening and pharmacological characterization of ß-lactam derivatives as TRPM8 antagonists. SCIENTIFIC REPORTS. 10766-10779. 2017
- 1,3-diphenylpropan-1-ones as allosteric modulators of alpha7 nACh receptors with analgesic and antioxidant properties. FUTURE MEDICINAL CHEMISTRY. 731-749. 2016
- 1. Calcium Entry Through Thermosensory Channels. . ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 265-304. 2016
- Bradykinin Induces TRPV1 Exocytotic Recruitment in Peptidergic Nociceptors.. FRONTIERS IN PHARMACOLOGY. 1-12. 2016
- Increased expression of Trpv1 in peripheral terminals mediates thermal nociception in Fabry disease mouse model.. MOLECULAR PAIN. 1-16. 2016
- New transient receptor potential TRPV1, TRPM8 and TRPA1 channel antagonists from a single linear ß,¿-diamino ester scaffold. RSC ADVANCES. 6868-6877. 2016
- Specific promoter deacetylation of histone H3 is conserved across mouse models of Huntington's disease in the absence of bulk changes.. NEUROBIOLOGY OF DISEASE. 190-201. 2016
- Synthesis and in vitro, ex-vivo and in vivo activity of hybrid compounds linking a potent ROS and RNS scavenger activity with diverse substrates addressed to pass across the blood-brain barrier. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 788-802. 2016
- TRPV1 channel modulation by hyaluronan reduces pain.. CHANNELS. 81-82. 2016
- Transient Receptor Potential Melastatin 8 Channel (TRPM8) Modulation: Cool Entryway for Treating Pain and Cancer.. JOURNAL OF MEDICINAL CHEMISTRY. 10006-10029. 2016
- Tryptamine-based derivatives as Transient Receptor Potential Melastatin type-8 (TRPM8) channel modulators. JOURNAL OF MEDICINAL CHEMISTRY. 2179-2191. 2016
- Whirlin increases TRPV1 channel expression and cellular stability.. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 115-127. 2016
- Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain. NATURE COMMUNICATIONS. 8095-8106. 2015
- TRP channels interaction with lipids and its implications in disease.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1818-1827. 2015
- TRPV1 channel modulation by hyaluronan reduces pain. CHANNELS. 2015
- The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating. BIOPHYSICAL JOURNAL. 529-541. 2015
- Adamantyl Analogues of Acetaminophen as Potent Analgesic Drugs. PLOS ONE. 1-9. 2014
- Chalcones as positive allosteric modulators of a7 nicotinic acetylcholine receptors: A new target for a privileged structure. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 724-729. 2014
- De Novo Designed Library of Linear Helical Peptides: An Exploratory Tool in the Discovery of Protein-Protein Interaction Modulators.. ACS COMBINATORIAL SCIENCE. 250-258. 2014
- Mutation of I696 and W697 in the Trp box of vanilloid receptor subtype I modulates allosteric channel activation. JOURNAL OF GENERAL PHYSIOLOGY. 361-375. 2014
- Neurotrophins, endocannbinoids and thermo-transient receptor potential: a threesome in pain signalling. EUROPEAN JOURNAL OF NEUROSCIENCE. 353-362. 2014
- The region adjacent to the C-end of the inner gate in Transient Receptor Potential Melastatin 8 (TRPM8) channels plays a central role in allosteric channel activation. JOURNAL OF BIOLOGICAL CHEMISTRY. 28579-28594. 2014
- aCGRP is essential for algesic exocytotic mobilization of TRPV1 channels in peptidergic nociceptors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 18250-18256. 2014
- A non-cannonical di-acidic signal at the C-terminus of Kv1.3 determines anterograde trafficking and surface expression. JOURNAL OF CELL SCIENCE. 5681-5691. 2013
- Detergent-labile, supramolecular assemblies of KcsA: relative abundance and interactions involved. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 193-200. 2013
- Highly functionalized 1,2¿diamino compounds through reductive amination of amino acid-derived ß¿keto esters. . PLOS ONE. 1-9. 2013
- Local delivery of molecules from a nanopipette for quantitative receptor mapping on live cells. ANALYTICAL CHEMISTRY. 9333-9342. 2013
- Potentiation of the transient receptor potential vanilloid I channel contribures to pruritogenesis in a rat model of liver disease. JOURNAL OF BIOLOGICAL CHEMISTRY. 9675-9685. 2013
- Sphingosine-1-phosphate-induced nociceptor excitation and ongoing pain behaviour in nmice and humans is largely mediates by S1P3 receptor. JOURNAL OF NEUROSCIENCE. 2582-2592. 2013
- Targeting protein-protein interactions to rescue ¿f508-cftr: a novel corrector approach to treat cystic fibrosis.. EMBO MOLECULAR MEDICINE. 1462-1464. 2013
- identification of voltage-gated K channel beta 2 subunit as a novel interaction partner of the pain transducer Transient Receptor Potential Vanilloid 1 Channel (TRPV1). BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 3166-3175. 2013
- Advances in modulating thermosensory TRP channels. EXPERT OPINION ON THERAPEUTIC TARGETS. 999-1017. 2012
- Agonist- and Ca-dependent desensitization of TRPV1 targets the receptor to lysosomes for degradation. JOURNAL OF BIOLOGICAL CHEMISTRY. 19462-19471. 2012
- Compound DD04107, an inhibitor of neuronal exocytosis, displays safe in vivo, long-lasting analgesic activity against chronic inflammatory and neuropathic pain. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 634-645. 2012
- Contribution of ion binding affinity to ion selectivity and permeation in KcsA, a model potassium channel.. BIOCHEMISTRY. 3891-3900. 2012
- Detergent-labile, supramolecular assemblies of KcsA: relative abundance and interactions involved.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 0-11. 2012
- In silico-based direct evolution of peptides and peptidomimetics in drug discovery. CURRENT TOPICS IN PHARMACOLOGY. 35-55. 2012
- Mutation of Ser-50 and Cys-66 in Snapin Modulates Protein Structure and Stability. BIOCHEMISTRY. 3470-3484. 2012
- New strategies to develop novel pain therapies: Addressing thermoreceptors from different points of view.. PHARMACEUTICALS. 16-48. 2012
- Complex regulation of TRPV1 and related thermoTRPs: implications for therapeutic intervention. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 1958-1970. 2011
- Estrogen destabilizes microtubules through an ion-conductivity-independent TRPV1 pathway. JOURNAL OF NEUROCHEMISTRY. 5397-5404. 2011
- Ionic channels as targets for drug design: a review on computational methods. PHARMACEUTICS. 1-11. 2011
- Membrane-tethered peptides patterned after the TRP domain (TRPducins) potently and selectively inhibit TRPV1 channel activity. . FASEB J. 1628-1640. 2011
- New modulators of TRPV1 receptors: structure-activity relationships using a rational combiantorial approach. . BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 3541-3545. 2011
- Rab4 interacts with the human P-glycoprotein and modulates its surface expression in multidrug resistant K562 cells. INTERNATIONAL JOURNAL OF CANCER. 192-205. 2011
- Solid-phase synthesis of a library of amphipatic hydantoins. Discovery of new hits for TRPV1 blockade. ACS CHEMICAL BIOLOGY. 458-465. 2011
- The role of the transient receptor potential vanilloid 1 (TRPV1) in inflammation and sepsis.. JOURNAL OF INFLAMMATION RESEARCH. 67-81. 2011
- Triazine-based Vanilloid-1 Receptor Open Channel Blockers: Design, Synthesis, Evaluation and SAR analysis.. JOURNAL OF MEDICINAL CHEMISTRY. 2011
- Contribution of Ion Channel Trafficking to Nociceptor Sensitization. THE OPEN PAIN JOURNAL. 108-116. 2010
- GABAA receptor associated protein (GABARAP) modulates TRPV1 expression and channel function and desensitization. FASEB J. 1958-1970. 2010
- Ion binding to KcsA: implications in ion selectivity and channel gating. BIOCHEMISTRY. 9480-9487. 2010
- Mechanisms of Nociceptor Sensitization. THE OPEN PAIN JOURNAL. 66-67. 2010
- Occupancy of non-annular lipid Binding sites on kcsA greatly increases the stability of the tetrameric protein. . BIOCHEMISTRY. 5397-5404. 2010
- RAB4 interacts with the human P-glycoprotein and modulates its surface expression in multidrug resistant K562 cells.. INTERNATIONAL JOURNAL OF CANCER. 192-205. 2010
- Solid-phase synthesis of new Trp(Nps)-containing dipeptide derivatives as TRPV1 channel blockers.. MOLECULES. 4924-4933. 2010
- Differential contribution of snare-dependent exocytosis to inflammatory potentiation of TRPV1 in nociceptors. FASEB J. 3722-3733. 2009
- Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels.. MOLECULAR PAIN. 62-75. 2009
- TRPA1 modulators in preclinical development. EXPERT OPINION ON THERAPEUTIC PATENTS. 1787-1799. 2009
- Identification of molecular determinants of channel gating in the transient receptor potential box of vanilloid receptor I. FASEB J. 3298-3306. 2008
- Molecular modelling of the full length human TRPV1 channel in a closed and desensitized states. JOURNAL OF MEMBRANE BIOLOGY. 161-172. 2008
- NMDA-INDUCED NEUROPROTECTION IN HIPPOCAMPAL NEURONS IS MEDIATED THROUGH THE PROTEIN KINASE A AND CREB (cAMP-RESPONSE ELEMENT-BINDING PROTEIN) PATHWAY. NEUROCHEMISTRY INTERNATIONAL. 148-154. 2008
- SYNTHESIS OF A POSSITIONAL SCANNING LIBRARY OF PENTAMERS OF N-ALKYLGLYCINES ASSISTED BY MICROWAVE ACTIVATION AND VALIDATION VIA THE IDENTIFICATION OF TRYPSIN INHIBITORS. JOURNAL OF COMBINATORIAL CHEMISTRY. 974-980. 2008
- TRPC CHANNELS AND DIACYLGLYCEROL DEPENDENT CALCIUM SIGNALING IN RAT SENSORY NEURONS. HISTOCHEMISTRY AND CELL BIOLOGY. 655-667. 2008
- A Role of the Transient Receptor Potential Domain of Vanilloid Receptor I in Channel Gating. JOURNAL OF NEUROSCIENCE. 11641-11650. 2007
- Design and synthesis of indole based peptoids as potent TRPV1 antagonists. JOURNAL OF MEDICINAL CHEMISTRY. 6133-6143. 2007
- Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflamatory activity.. JOURNAL OF PAIN. 735-746. 2006
- Pharmacological intervention at ionotropic glutamate receptors. CURRENT PHARMACEUTICAL DESIGN. 3583-3596. 2006
- Physiology and Pharmacology of the Vanilloid receptor. . CURRENT NEUROPHARMACOLOGY. 1-15. 2006
- Small molecule inhibitors of Apaf-1-related caspase-3/-9 activation that control mitochondrial-dependent apoptosis. CELL DEATH AND DIFFERENTIATION. 1523-1532. 2006
- characterization of a neural-specific splicing form of the human neuregulin 3 gene involved in oligodendrocyte survival. JOURNAL OF CELL SCIENCE. 898-909. 2006
- Acquisition of multidrug resistance by L1210 leukemia cells decreases their tumorigenicity and enhances their susceptibility to the host immune response. CANCER IMMUNOLOGY IMMUNOTHERAPY. 328-336. 2005
- Design and synthesis of an optimized positional scanning library of peptoids: identification of novel multidrug resistance reversal agents. BIOORGANIC & MEDICINAL CHEMISTRY. 1923-1929. 2005
- Molecular compatibility of the channel gate and the N-terminus of S5 segment for voltage-gated channel activity. JOURNAL OF BIOLOGICAL CHEMISTRY. 18253-18264. 2005
- functional aspects and mechanisms of trpv1 involvement in neurogenic inflammation that leads to thermal hyperalgesia. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 151-159. 2005
- Design of bioactive and structurally well-defined peptides from conformationally restricted libraries. BIOPOLYMERS. 357-365. 2004
- Identification of a tetramerization domain in the C-terminus of the the vanilloid receptor. JOURNAL OF NEUROSCIENCE. 5307-5314. 2004
- Modulation of botulinum neurotoxin A catalytic domain by tyrosine phosphorylation. FEBS LETTERS. 121-127. 2004
- Molecular architecture of the vanilloid receptor: insights for drug design. EUROPEAN JOURNAL OF BIOCHEMISTRY. 1820-1826. 2004
- Oligomerization of sensory motor derved factor prevents the protein O-glycosylation. JOURNAL OF BIOLOGICAL CHEMISTRY. 33623-33629. 2004
- Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity. JOURNAL OF BIOLOGICAL CHEMISTRY. 25665-25672. 2004
- Small peptides patterned after the n-terminus domain of snap25 Inhibit snare complex assembly and regulated exocytosis. JOURNAL OF NEUROCHEMISTRY. 124-135. 2004
- Synthesisof a library of 3-oxopiperazinium and (6H)-3-oxohexahydro-1,4-diazepinium derivatives and identification of bioactive compounds . JOURNAL OF COMBINATORIAL CHEMISTRY. 135-141. 2004
- GAP43 is an osmotic-dependent activator of inositol triphosphate-mediated Ca2+-release. EMBO JOURNAL. 3004-3014. 2003
- Identification of SNARE complex modulators that inhibit exocytosis from an a-helix-constrained combinatorial library. BIOCHEMICAL JOURNAL. 159-166. 2003
- New applications of herbal extracts for functional food and pharmaceuticals. Part 1. AGRO FOOD INDUSTRY HI-TECH. 62-64. 2003
- New applications of herbal extracts for functional food and pharmaceuticals. Part 2. AGRO FOOD INDUSTRY HI-TECH. 14-16. 2003
- A novel N-Methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity.. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 163-173. 2002
- Attenuation of Chemical and Thermal Nociception and Hyperalgesia by Novel VR1 Blockers.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES. 2374-2379. 2002
- Attenuation of chemical and thermal nociception and hyperalgesia by novel VR1 blockers.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME. 2374-2379. 2002
- Molecular determinants of sensory and motor neuron derived factor insertion into plasma membrane.. JOURNAL OF BIOLOGICAL CHEMISTRY. 19905-19912. 2002
- Prevention of in vivo excitotoxicity by a family of trialkylglicines, a novel class of neuroprotectants.. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 29-36. 2002
- Tyrosine Phosphorylation of the Inactivating Peptide of the Shaker B Potassium Channel: A Structural-Functional Correlate.. BIOCHEMISTRY. 12263-12269. 2002
- A family of trialkylglycines with in vitro and in vivo neuroprotective activity against excitotoxicity.. SOCIETY FOR NEUROSCIENCE ABSTRACTS. 2001
- A member of the HIT protein family interacts with VR-1 Society for Neurosciences.. SOCIETY FOR NEUROSCIENCE ABSTRACTS. 2001
- Structural adaptability between the putative voltage sensor of Kv channels and the prokaryotic HCSA channel.. JOURNAL OF BIOLOGICAL CHEMISTRY. 21070-21076. 2001
- Targeting and delivery of small peptides patterned after the N-terminus domain of SNAP-25 that inhibit regulated exocytosis.. SOCIETY FOR NEUROSCIENCE ABSTRACTS. 2001
- Thermal stabilization of the catalytic domain of Botulinum Neurotoxin E by phosphosylation of a single tyrosine residue.. BIOCHEMISTRY. 2234-2242. 2001
- Arginine rich peptides are blockers of VR-1 channels with analgesic activity. FEBS LETTERS. 131-136. 2000
- Identification of VR-1 channel blockers that exhibit analgesic activity.. EUROPEAN JOURNAL OF NEUROSCIENCE. 2000
chapter
- TRP channels in sensory transduction. Pharmacology of TRP Channels. En: TRP channels in sensory transduction.. 41-71. 2015
- Complex Regulation of TRPV1 and Related ThermoTRPs: Implications for therapeutic intervention. Transient Receptor Potential Channels. 1-28. 2010
- TRP channel trafficking. TRP ION CHANNEL FUNCTION IN SENSORY TRANSDUCTION AND CELLULAR SIGNALLING CASCADES467. 319-330. 2006
congress communication
patent

presentations

invited conference
- Mecanismo molecular y evidencia clínica de la modulación tópica de la neuropatía por quimioterapia Antonio Ferrer Montiel , Conferencia 2024
- Reforming Research Assessment , Conferencia 2023
- Fabricando neuronas para estudiar el dolor, Conferencia 2023
- Translation into biotechnology, Conferencia 2018
- Entrepreneurship, moving away from academia, Conferencia 2017
- Molecular Mechanims of TRPV1 inflammatory sensitization, Conferencia 2014
- TRPducins: a novel paradigm to modulate ion channel signalling, Conferencia 2012
- A bioentrepreneurial experience: learning from failure, Conferencia 2012
- Allosteric) modulation) of) TRPV1) channels) as) a) novel), Conferencia 2012
- TRPducins: a novel paradigm to modulate ion channel activity, Conferencia 2011
- Papel del dominio TRP de TRPV1 en la función, Conferencia 2011
- TRPducins a novel paradigm to modulate ion channel activity, Conferencia 2011
- TRP domain implications in TRP channels function, Conferencia 2010
- Estructura-función en el termorreceptor TRPV1. , Conferencia 2009
- Neurogenic Inflammation and Sensitive Skin: a Paradigm for Innovative Cosmeceutical Intervention , Conferencia 2008
- Molecular biology of pain transduction., Conferencia 2007
- Creación de una empresa de Spin-off. , Conferencia 2007
- Molecular pharmacology of the vanilloid receptor: Insights on pain therapeutics, Conferencia 2007
- Creación y gestión de una empresa de Spin-off., Conferencia 2007
- Structure and Pharmacology of the Vanilloid Receptor., Conferencia 2007
- Departamento de Biología Celular. Biología Molecular del Dolor y diseño de analgésicos y antiinflamatorios, Conferencia 2007
- Structure and Pharmacology of the Vanilloid Receptor, Conferencia 2007
- Molecular design of membrane sensing: channels of communication, Conferencia 2006
- Therapeutic and Cosmetic properties of botulinomimetic peptides. , Conferencia 2005
- Protein components in the Pain Pathway. , Conferencia 2005
- MEMBRANE MECHANISMS OF TRPV1 INFLAMMATORY SENSITIZATION , Conferencia 2004
- BIOLOGIA MOLECULAR DEL DOLOR, Conferencia 2004
- EL DESCUBRIMIENTO DE FARMACOS DEL SIGLO XX1, Conferencia 2004
- STRUCTURE, FUNCTION AND PATOPHYSIOLOGY OF TRPV1 RECEPTORS, Conferencia 2004
- EL DESCUBRIMIENTO DE FARMACOS EN EL SIGLO XXI, Conferencia 2004
- BIOLOGIA MOLECULAR DEL DOLOR, Conferencia 2004
- BIOLOGY OF PAIN TRANSDUCTION: A THERAPEUTIC OPPORTUNITY, Conferencia 2004
- Los canales de comunicación de la Vida, Conferencia 2003
- Vanilloid receptors in pain, Conferencia 2003
- Molecular Biology of Pain Transduction, Conferencia 2003
- TRPV1 involvement in inflammatory pain: mechanims and pharmacological modulation, Conferencia 2003
- Aplicación de la Química Combinatoria para la validación de dianas terapéuticas, Conferencia 2003
- Bases Moleculares del Dolor., Conferencia
- Busqueda de nuevos neuroprotectores., Conferencia
- Determinantes moleculares del poro iónico del termoreceptor VR1., Conferencia
- Diseño Irracional en Biología: la estrategia combinatoria., Conferencia
- Diseño irracional de Fármacos: Quimiotecas combinatorias., Conferencia
- Drug discovery and pharmacogenomics., Conferencia
- Drug discovery in the Post-genomic era., Conferencia
- Estrategias y nuevas tecnologías para el descubrimiento de fármacos., Conferencia
- FVIjB: Diseño Irracional en Biología: la estrategia combinatoria., Conferencia
- Identificación de nuevas moléculas bioactivas mediante química combinatoria., Conferencia
- Identificación y caracterización de bloqueadores de VR1 que atenúan el dolor inflamatorio., Conferencia
- Molecular determinants of the pore-forming region of VR1 channels., Conferencia
- Role of vanilloid receptor I in inflammatory pain., Conferencia
- Why are botulinum neurotoxins the most potent toxins to humankind?., Conferencia