NADAL NAVAJAS, ANGEL

Person (Active)

Positions

RESPONSABLE DE UNIDAD A EFECTOS DE FIRMA DE COMISIONES DE SERVICIO, Fisiología 2024 -
Catedrático/a de Universidad, Fisiología 2009 -
PDI INVESTIGADOR, Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2018 -
SUBDIRECTOR/A DE INSTITUTO, Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2019 -
SUBDIRECTOR/A DE INSTITUTO, Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2023 -
MIEMBRO, Unidad de Investigación Básica en Diabetes 2007 -
PDI INVESTIGADOR, Instituto de Biología Molecular y Celular 2018
PDI INVESTIGADOR, Instituto de Bioingeniería 2004 - 2018
Profesor/a Titular Universidad, Fisiología 2007 - 2009
Profesor Titular Universidad, Fisiología 2002 - 2007
Profesor Interino Titular Unv., Fisiología 2000 - 2002
Profesor Titular Universidad, FISIOLOGIA 1998 - 1999
Profesor Interino Titular Unv., FISIOLOGIA 1998 - 1999

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supported publications or other works

selected publications

academic article
- Consensus on the key characteristics of metabolism disruptors. NATURE REVIEWS ENDOCRINOLOGY. 1-17. 2024
- Hyperglucagonemia and glucagon hypersecretion in early type 2 diabetes result from multifaceted dysregulation of pancreatic mouse ¿-cells. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 1-14. 2024
- The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA). ENVIRONMENTAL HEALTH PERSPECTIVES. 1-16. 2024
- A vision for safer food contact materials: Public health concerns as drivers for improved testing. ENVIRONMENT INTERNATIONAL. 1-18. 2023
- BCL-XL Overexpression Protects Pancreatic ß-Cells against Cytokine- and Palmitate-Induced Apoptosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 5657. 2023
- Deucravacitinib, a tyrosine kinase 2 pseudokinase inhibitor, protects human EndoC-ßH1 ß-cells against proinflammatory insults. FRONTIERS IN IMMUNOLOGY. 126392-126393. 2023
- Endocrine disruptors in plastics alter ß-cell physiology and increase the risk of diabetes mellitus. AM J PHYSIOL-ENDOC M. 488-505. 2023
- Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a Healthy Environment and Endocrine Disruptors Strategies Workshop. AMERICAN JOURNAL OF CLINICAL NUTRITION. 329-337. 2023
- Screening of Metabolism-Disrupting Chemicals on Pancreatic Alpha-Cells Using In Vitro Methods. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 231. 2023
- G protein-coupled estrogen receptor activation by bisphenol-A disrupts the protection from apoptosis conferred by the estrogen receptors ER¿ and ERß in pancreatic beta cells. ENVIRONMENT INTERNATIONAL. 107250-107262. 2022
- In Vitro Assays to Identify Metabolism-Disrupting Chemicals with Diabetogenic Activity in a Human Pancreatic ß-Cell Model. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 5040-5058. 2022
- The pancreatic beta-cell in ageing: Implications in age-related diabetes. AGEING RESEARCH REVIEWS. 1-11. 2022
- CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model. FRONTIERS IN IMMUNOLOGY. 1-11. 2021
- The effects of aging on male mouse pancreatic ß-cell function involve multiple events in the regulation of secretion: influence of insulin sensitivity. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 1-11. 2021
- Ventricular Fibrosis and Coronary Remodeling Following Short-Term Exposure of Healthy and Malnourished Mice to Bisphenol A. FRONTIERS IN PHYSIOLOGY. 1-10. 2021
- Bisphenol-A exposure during pregnancy alters pancreatic ß-cell division and mass in male mice offspring: A role for ERß. FOOD AND CHEMICAL TOXICOLOGY. 111681-111691. 2020
- Bisphenol-S and Bisphenol-F alter mouse pancreatic ß-cell ion channel expression and activity and insulin release through an estrogen receptor ERß mediated pathway. CHEMOSPHERE. 1-14. 2020
- Impacts of food contact chemicals on human health: a consensus statement. ENVIRONMENTAL HEALTH. 1-12. 2020
- Morphological and functional adaptations of pancreatic alpha-cells during late pregnancy in the mouse. METABOLISM-CLINICAL AND EXPERIMENTAL. 153963-153973. 2020
- The Commonly Overlooked Factor. Commentary on: ¿Environmental Obesogens and their Impact on Susceptibility to Obesity¿. ENDOCRINOLOGY. 1-2. 2020
- The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 1-18. 2020
- Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception. SCIENTIFIC REPORTS. 1-14. 2019
- Editorial: Endocrine Disrupters and Metabolism. FRONTIERS IN ENDOCRINOLOGY. 1-3. 2019
- In utero exposure to bisphenol-A disrupts key elements of retinoid system in male mice offspring. FOOD AND CHEMICAL TOXICOLOGY. 142-151. 2019
- Oestrogen receptor ß mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells. DIABETOLOGIA. 1667-1680. 2019
- Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes. SCIENTIFIC REPORTS. 1-12. 2019
- Update on Activities in Endocrine Disruptor Research and Policy. ENDOCRINOLOGY. 1681-1683. 2019
- A Calcium-Dependent Chloride Current Increases Repetitive Firing in Mouse Sympathetic Neurons. FRONTIERS IN PHYSIOLOGY. 1-15. 2018
- Cortistatin regulates glucose-induced electrical activity and insulin secretion in mouse pancreatic beta-cells. MOLECULAR AND CELLULAR ENDOCRINOLOGY. 123-132. 2018
- Experimental BPA Exposure and Glucose-Stimulated Insulin Response in Adult Men and Women. JOURNAL OF THE ENDOCRINE SOCIETY. 1173-1187. 2018
- Marine litter plastics and microplastics and their toxic chemicals components. the need for urgent preventive measures. ENVIRONMENTAL SCIENCE EUROPE. 1-14. 2018
- Mitochondria as target of endocrine-disrupting chemicals: implications for type 2 diabetes. JOURNAL OF ENDOCRINOLOGY. 27-45. 2018
- ENDOCRINE DISRUPTING CHEMICALS AND THE REGULATION OF ENERGY BALANCE. NATURE REVIEWS ENDOCRINOLOGY. 536-546. 2017
- Effects of bisphenol A treatment during pregnancy on kidney development in mice: a stereological and histopathological study. JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE. 1-7. 2017
- Extranuclear-initiated estrogenic actions of endocrine disrupting chemicals: Is there toxicology beyond paracelsus?. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 1-7. 2017
- GPR55 and the regulation of glucose homeostasis. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 204-207. 2017
- La acción oculta de los disruptores endocrinos. INVESTIGACION Y CIENCIA. 50-57. 2017
- Molecular mechanisms involved in the non-monotonic effect of bisphenol-A on Ca2+ entry in mouse pancreatic ß-cells.. SCIENTIFIC REPORTS. 1-15. 2017
- Polluted Pathways: Mechanisms of Metabolic Disruption by Endocrine Disrupting Chemicals.. CURRENT ENVIRONMENTAL HEALTH REPORTS. 208-222. 2017
- Effects of Bisphenol A on ion channels: experimental evidence and molecular mechanisms. STEROIDS. 12-20. 2016
- Glucagon-Like Peptide 1 Analogs and their Effects on Pancreatic Islets. TRENDS IN ENDOCRINOLOGY AND METABOLISM. 304-318. 2016
- Lacking of estradiol reduces insulin exocytosis from pancreatic ß-cells and increases hepatic insulin degradation.. STEROIDS. 16-24. 2016
- MATERNAL EXPOSURE TO BISPHENOL-A DURING PREGNANCY INCREASES PANCREATIC ß-CELL GROWTH DURING EARLY LIFE IN MALE MICE OFFSPRING. ENDOCRINOLOGY. 4158-4171. 2016
- Metabolism disrupting chemicals and metabolic disorders. REPRODUCTIVE TOXICOLOGY. 1-31. 2016
- The bile acid TUDCA increases glucose-induced insulin secretion via the cAMP/PKA pathway in the pancreatic beta-cell.. METABOLISM-CLINICAL AND EXPERIMENTAL. 54-63. 2016
- Uppsala Consensus Statement on Environmental Contaminants and the Global Obesity Epidemic. ENVIRONMENTAL HEALTH PERSPECTIVES. 81-83. 2016
- Bisphenol-A exposure during pregnancy in mice: a new window of susceptibility for the development of diabetes and obesity in mothers later in life. ENDOCRINOLOGY. 1659-1670. 2015
- EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals. ENDOCRINE REVIEWS. 1-150. 2015
- Enhanced glucose-induced intracellular signaling promotes insulin hypersecretion: pancreatic beta-cell functional adaptations in a model of genetic obesity and prediabetes. MOLECULAR AND CELLULAR ENDOCRINOLOGY. 46-55. 2015
- Executive Summary to EDC-2: The Endocrine Society¿s Second Scientific Statement on Endocrine-Disrupting Chemicals. ENDOCRINE REVIEWS. 593-602. 2015
- Pancreatic alpha-cells from female mice undergo morphofunctional changes during compensatory adaptations of the endocrine pancreas to diet-induced obesity.. SCIENTIFIC REPORTS. 11622-11622. 2015
- Prenatal exposure to BPA and offspring outcomes: the diabesogenic behaviour of BPA. DOSE-RESPONSE. 1-8. 2015
- Taurine supplementation ameliorates glucose homeostasis, prevents insulin and glucagon hypersecretion, and controls beta, alpha, and delta-cell masses in genetic obese mice. AMINO ACIDS. 1533-1548. 2015
- Cyclin D3 promotes pancreatic b-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME. 3405-3414. 2014
- Exposure to bisphenol-A during pregnancy partially mimics the effects of a high-fat diet altering glucose homeostasis and gene expression in adult male mice. PLOS ONE. 10021-100213. 2014
- Glucocorticoid treatment and endocrine pancreas function: implications for glucose homeostasis, insulin resistance and diabetes. JOURNAL OF ENDOCRINOLOGY. 49-62. 2014
- Inhibition of connexin 36 hemichannels by glucose contributes to the stimulation of insulin secretion.. AM J PHYSIOL-ENDOC M. 1354-1366. 2014
- Nutrient regulation of glucagon secretion: involvement in metabolism and diabetes. NUTRITION RESEARCH REVIEWS. 48-62. 2014
- Pancreatic alpha-cell dysfunction contributes to the disruption of glucose homeostasis and compensatory insulin hypersecretion in glucocorticoid-treated rats. PLOS ONE. 93531-935311. 2014
- Antidiabetic actions of an estrogen receptor beta selective agonist.. DIABETES. 2015-2025. 2013
- Insulin Hypersecretion in Islets From Diet-Induced Hyperinsulinemic Obese Female Mice Is Associated With Several Functional Adaptations in Individual beta-Cells.. ENDOCRINOLOGY. 3515-3524. 2013
- Involvement of the clock gene Rev-erb alpha in the regulation of glucagon secretion in pancreatic alpha-cells.. PLOS ONE. 699391-699399. 2013
- Linking intermittent hypoxia, sympathetic response and metabolic disturbances. ACTA PHYSIOLOGICA. 7-8. 2013
- Obesity: Fat from plastics? Linking bisphenol A exposure and obesity. NATURE REVIEWS ENDOCRINOLOGY. 9-10. 2013
- Short-Term Treatment with Bisphenol-A Leads to Metabolic Abnormalities in Adult Male Mice . PLOS ONE. 1-10. 2012
- Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways. MOLECULAR AND CELLULAR ENDOCRINOLOGY. 201-207. 2012
- Functional and Structural Adaptations in the. ENDOCRINOLOGY. 1663-1672. 2012
- Insulinotropic Effect of the Non-Steroidal Compound STX. PLOS ONE. 1-11. 2012
- Rapid Insulinotropic Action of Low Doses of Bisphenol-A. PLOS ONE. 1-9. 2012
- Role of ERb and GPR30 in the endocrine pancreas: a matter of estrogen dose. STEROIDS. 2012
- Role of leptin in the pancreatic beta-cell: effects and signaling pathways.. JOURNAL OF MOLECULAR ENDOCRINOLOGY. 9-17. 2012
- The clock gene Rev-erbalpha regulates pancreatic beta-cell function: modulation by leptin and high-fat diet. ENDOCRINOLOGY. 592-601. 2012
- A Water-Soluble Perylene Dye Functionalised with a 17¿-estradiol: a new Fluorescent Tool for Steroid Hormones. CHEMICAL COMMUNICATIONS. 8307-8309. 2011
- A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans. JOURNAL OF ENDOCRINOLOGY. 177-185. 2011
- Endocrine disruptors in the etiology of type 2 diabetes mellitus. NATURE REVIEWS ENDOCRINOLOGY. 346-353. 2011
- Endocrine disruptors in the etiology of type 2 diabetes mellitus.. NATURE REVIEWS ENDOCRINOLOGY. 346-353. 2011
- Involvement of ATP-Sensitive Potassium (KATP) Channles in the Loss of Beta-cell function induced by human islet amyloid polypeptide. JOURNAL OF BIOLOGICAL CHEMISTRY. 40857-40866. 2011
- Leptin downregulates expression of the gene encoding glucagon in alphaTC1-9 cells and mouse islets.. DIABETOLOGIA. 843-851. 2011
- Regulation of K(ATP) channel by 17ß-estradiol in pancreatic ß-cells. STEROIDS. 856-860. 2011
- Regulation of K(ATP) channel by 17ß-estradiol in pancreatic ß-cells.. STEROIDS. 856-60. 2011
- Role of estrogen receptors alpha, beta and GPER1/GPR30 in pancreatic beta-cells. FRONTIERS IN BIOSCIENCE. 256-260. 2011
- Role of estrogen receptors alpha, beta and GPER1/GPR30 in pancreatic beta-cells.. FRONTIERS IN BIOSCIENCE. 251-260. 2011
- The F-actin cortical network is a major factor influencing the organization of the secretory machinery in chromaffin cells. JOURNAL OF CELL SCIENCE. 727-734. 2011
- Bisphenol A exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring. ENVIRONMENTAL HEALTH PERSPECTIVES. 1243-1250. 2010
- Bisphenol-A Exposure during Pregnancy Disrupts Glucose Homeostasis in Mothers and Adult Male Offspring. ENVIRONMENTAL HEALTH PERSPECTIVES. 1243-1250. 2010
- Bisphenol-A a new diabetogenic factor?. HORMONES (ATHENS). 118-126. 2010
- Bisphenol-A: a new diabetogenic factor?. HORMONES (ATHENS). 118-126. 2010
- Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research.. TOXICOLOGICAL SCIENCES. 612-613. 2010
- Glucocorticoids in Vivo Induce Both Insulin Hypersecretion and Enhanced Glucose Sensitivity of Stimulus-Secretion Coupling in Isolated Rat Islets. ENDOCRINOLOGY. 85-95. 2010
- Islets of Langerhans from guanylyl ciclase-A KO mice have decreased beta cell mass and improved glucose-induced insulin secretion. ENDOCRINOLOGY. 3665-3674. 2010
- La leptina inhibe la expresión de glucagón en células alfa pancreáticas a través de STAT3. ENDOCRINOLOGIA Y NUTRICION. 88-88. 2010
- Pancreatic islet cells: a model for calcium-dependent peptide release. HFSP JOURNAL. 52-60. 2010
- Position paper: Rapid responses to steroids: current status and future prospects.. EUROPEAN JOURNAL OF ENDOCRINOLOGY. 825-830. 2010
- Rapid responses to steroid hormones. Preface.. STEROIDS. 519-519. 2010
- Reduced insulin secretion in protein malnourished mice is associated to multiple changes in the beta-cell stimulus-secretion coupling. ENDOCRINOLOGY. 3543-3554. 2010
- Inhibitory effects of leptin on the pancreatic alpha-cell function. DIABETES. 1616-1624. 2009
- Lysophosphatidic acid induces Ca2+ mobilization and c-Myc expression in mouse embryonic stem cells via the phospholipase C pathway. CELLULAR SIGNALLING. 523-528. 2009
- Modulation of pancreatic alpha-cell function by leptin involves effects on electrical activity, calcium signalling and exocytosis. PROCEEDINGS OF THE PHYSIOLOGICAL SOCIETY. 94-94. 2009
- Novel ER¿ and ERß mediated actions in mouse pancreatic ß-cells. PROCEEDINGS OF THE PHYSIOLOGICAL SOCIETY. 209-210. 2009
- REGULATION OF GLUCOSE-INDUCED [Ca2+]i SIGNALS BY CANNABINOID RECEPTORS CB1 AND CB2 IN PANCREATIC ¿- AND ¿- CELLS WITHIN INTACT ISLETS OF LANGERHANS. OBESITY AND METABOLISM. 20-28. 2009
- Rapid Regulation of KATP Channel Activity by 17{beta}-Estradiol in Pancreatic {beta}-Cells Involves the Estrogen Receptor {beta} and the Atrial Natriuretic Peptide Receptor.. MOLECULAR ENDOCRINOLOGY. 1973-1982. 2009
- Rapid non-genomic regulation of Ca2+ signals and insulin secretion by PPAR alpha ligands in mouse pancreatic islets of Langerhans. JOURNAL OF ENDOCRINOLOGY. 127-138. 2009
- Role of iduronate-2-sulfatase in glucose-stimulated insulin secretion by activation of exocytosis. AM J PHYSIOL-ENDOC M. 793-801. 2009
- The pancreatic beta-cell as a target of estrogens and xenoestrogens: Implications for blood glucose homeostasis and diabetes. MOLECULAR AND CELLULAR ENDOCRINOLOGY. 63-68. 2009
- The role of estrogens in the adaptation of islets to insulin resistance. JOURNAL OF PHYSIOLOGY-LONDON. 5031-5038. 2009
- The role of pancreatic endocannabinoid system in glucose metabolism. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM. 87-102. 2009
- Why Public Health Agencies Cannot Depend on Good Laboratory Practices as a Criterion for Selecting Data: The Case of Bisphenol-A. ENVIRONMENTAL HEALTH PERSPECTIVES. 309-315. 2009
- Activación del proceso de exocitosis mediado por PKCalfa/betaII en células beta-pancreáticas que sobrexpresan la enzima lisosomal iduronato-2-sulfatasa. AVANCES EN DIABETOLOGIA. 49-50. 2008
- Bisphenol-A disruption of the endocrine pancreas and blood glucose homeostasis.. INTERNATIONAL JOURNAL OF ANDROLOGY. 194-200. 2008
- Pancreatic Insulin Content Regulation by the Estrogen Receptor ERa. PLOS ONE. 2069-2079. 2008
- Pancreatic insulin content regulation by the estrogen receptor ER alpha. PLOS ONE. 2069-2081. 2008
- Physiology of the pancreatic alpha-cell and glucagon secretion: role in glucose homeostasis and diabetes. JOURNAL OF ENDOCRINOLOGY. 5-19. 2008
- Presence of functional cannabinoid receptors in human endocrine pancreas.. DIABETOLOGIA. 476-487. 2008
- Rapid regulation of pancreatic alpha- and beta- cell signalling systems by estrogens. INFECTIOUS DISORDERS - DRUG TARGETS. 61-64. 2008
- Rapid regulation of pancreatic alpha- and beta- cell signalling systems by estrogens.. INFECTIOUS DISORDERS - DRUG TARGETS. 61-64. 2008
- Salicylates increase insulin secretion in healthy obese subjects. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2523-2530. 2008
- The role of estrogen receptors in the control of energy and glucose homeostasis. STEROIDS. 874-879. 2008
- Bisphenol-A disruption of the endocrine pancreas and blood glucose homeostasis. INTERNATIONAL JOURNAL OF ANDROLOGY. 1-6. 2007
- Chapel Hill bisphenol-A experte panel consensus statement: integration of mechanisms, effects in animals and potential ti impact human health at current levels of exposure. REPRODUCTIVE TOXICOLOGY. 131-138. 2007
- Glucose induces synchronous mitochondrial calcium oscillations in intact pancreatic islets.. CELL CALCIUM. 2007
- Impact of over-expression of iduronate-2-sulfatase (IDS) on glucose-stimulated insulin secretion.. DIABETOLOGIA. 225-226. 2007
- In vitro Molecular Mechanisms of Bisphenol-A action. REPRODUCTIVE TOXICOLOGY. 178-198. 2007
- PPAR(alpha) agonists effect on insulin secretion in pancreatic beta-cells by a non genomic mechanism. ACTA PHYSIOLOGICA. 83-83. 2007
- Role of cannabinoid CB2 receptors in glucose homeostasis in rats. EUROPEAN JOURNAL OF PHARMACOLOGY. 207-211. 2007
- The estrogen receptor ERalpha mediates 17beta-estradiol and xenoestrogens up-regulation of pancreatic insulin content via a non-classical pathway. ACTA PHYSIOLOGICA. 58-59. 2007
- The role of estrogen receptors in the control of energy and glucose homeostasis.. STEROIDS. 2007
- Activation of cannabinoid CB1 receptors induces glucose intolerance in rats.. EUROPEAN JOURNAL OF PHARMACOLOGY. 282-284. 2006
- Cannabinoid receptors regulate Ca2+ signals and insulin secretion in pancreatic beta-cell. CELL CALCIUM. 155-162. 2006
- Estrogen and xenoestrogens alter pancreatic function and insulin release. PERIODICUM BIOLOGORUM. 83-84. 2006
- Genistein Affects Adipose Tissue Deposition in a Dose-Dependent and Gender-Specific Manner. ENDOCRINOLOGY. 5740-5751. 2006
- Glucose Induces Opposite Intracellular calcium concentration Oscillatory Patternes in Identified alfa and beta cells within Human Islets of langerhans. DIABETES. 2463-2469. 2006
- The estrogenic effect of Bisphenol-A disrupts the pancreatic ¿Ò-cell function in vivo and induces insulin resistance. ENVIRONMENTAL HEALTH PERSPECTIVES. 106-112. 2006
- The estrogenic effect of Bisphenol-A disrupts the pancreatic ¿Ò-cell function in vivo and induces insulin resistance. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 163-169. 2006
- The mitogen lysophosphatidic acid produces Ca2+ signals in mouse embryonic stem cells. PROCEEDINGS OF THE PHYSIOLOGICAL SOCIETY. 178-178. 2006
- Bioluminescence imaging of nuclear calcium oscillations in mouse pancreatic islets of Langerhans.. CELL CALCIUM. 131-139. 2005
- Disentangling the molecular mechanisms of action of natural and environmental estrogens. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 335-343. 2005
- LPA induces Ca2+ signalling in mouse embryionic stem cells. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 261-261. 2005
- Low doses of bisphenol-a and diethylstilbestrol impair Ca2+ signals in pancreatic a-cells through a non-classical membrane estrogen receptor within intact islets of Langerhans. . ENVIRONMENTAL HEALTH PERSPECTIVES. 969-977. 2005
- Low doses of endocrine disruptors rapidly regulate calcium signalling in pancreatic alfa-cells via a cGMP-dependent protein kinase within intact islet of Langerhans from the mouse. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 89-89. 2005
- Pregnancy-associated increase of insulin content in mouse pancreatic beta cells is mimicked by natural and enviromental oestrogens. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 267-267. 2005
- Estrogen and xenoestrogen actions on endocrine pancreas: from ion channel modulation to activation of nuclear function. STEROIDS. 531-536. 2004
- Low doses of endocrine disruptors imitate rapid actions of 17¿Ò-estradiol on Ca2+ signals in pancreatic ¿Ñ-cells within intact islets of Langerhans. JOURNAL OF PHYSIOLOGY-LONDON. 49-49. 2004
- Novel players in pancreatic Islet Signaling. From membrane receptors to nuclear channels. DIABETES. 86-91. 2004
- Oestradiol rapidly inhibits Ca2+signals in ciliary neurons through classical oestrogen receptors in cytoplasm. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 33-41. 2004
- Bovine subcommisural organ displays spontaneous and synchronous intracellular calcium oscillations. BRAIN RESEARCH. 90-96. 2003
- Estradiol modulates acetylcholine-induced Ca2+ signals in LHRH releasing GT1-7 cells through a membrane binding site.. EUROPEAN JOURNAL OF NEUROSCIENCE. 2505-2514. 2003
- On-line analysis of gap junctions reveals more efficient electrical than dye coupling between islet cells . AM J PHYSIOL-ENDOC M. 980-987. 2003
- The endocrine disruptor Bisphenol-A and the native hormone 17beta-oestradiol rapidly activate transcription factor CREB in mouse pancreatic beta-cells. . JOURNAL OF PHYSIOLOGY-LONDON. 1-1. 2003
- A nonclassical estrogen membrane receptor triggers rapid differential actions in the endocrine pancreas.. MOLECULAR ENDOCRINOLOGY. 497-505. 2002
- Low doses of the endocrine disruptor bisphenol-a and the native hormone 17beta-estradiol rapidly activate the transcription factor creb.. FASEB J. 1671-1673. 2002
- Nuclear KATP channels trigger nuclear Ca2+ transients that modulate nuclear function .. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME. 9544-9549. 2002
- Cell engineering and diabetes mellitus.. REVISTA CLINICA ESPANOLA. 548-556. 2001
- Efectos rápidos de los xenoestrógenos por unión a un receptor en la membrana plasmática. NUTRITION. 11-12. 2001
- Efectos rápidos de los xenoestrógenos por unión a un receptor en la membrana plasmática. NUTRICION HOSPITALARIA. 234-234. 2001
- Efectos rápidos de los xenoestrógenos por unión a un receptor en la membrana plasmática.. NUTRICIÓN CLÍNICA Y DIETÉTICA HOSPITALARIA. 1-21. 2001
- Glial cells responses to lipids bound to albumin in serum and plasma.. PROGRESS IN BRAIN RESEARCH. 367-374. 2001
- KATP channels at the nuclear membrane induce nuclear Ca2+ signals and gene expression.. DIABETOLOGIA. 20-20. 2001
- LA SEÑAL DE CALCIO INDUCIDA POR ACETILCOLINA ES MODULADA DE FORMA RAPIDA POR ESTRADIOL EN LAS CELULAS GT1-7. REVISTA DE NEUROLOGIA. 768-768. 2001
- The estrogen trinity: membrane, cytosolic and nuclear effects.. NEWS IN PHYSIOLOGICAL SCIENCES. 251-255. 2001
- The plasma membrane estrogen receptor: nuclear or nuclear?. TRENDS IN PHARMACOLOGICAL SCIENCES. 597-599. 2001
- Engineering pancreatic islets.. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 1-18. 2000
- Different effects of tolbutamide and diazoxide in alpha, beta and delta cells within intact islets of Langerhans.. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 223-223. 1999
- Different effects of tolbutamide and diazoxide in alpha, beta and delta cells within intact islets of Langerhans.. DIABETES. 2390-2397. 1999
- HOMOLOGOUS AND HETEROLOGOUS UNSYNCHRONISITY BETWEEN IDENTIFIED ALPHA, BETA AND DELTA CELLS WITHIN INTACT ISLETS OF LANGERHANS . JOURNAL OF PHYSIOLOGY-LONDON. 85-93. 1999
- Homologous and heterologous unsynchronisity between identified alpha, beta and delta cells within intact islets of Langerhans.. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 222-222. 1999
- Control of insulin secretion by norepinephrine and acetylcholine in islets from malnourished rats. JOURNAL OF PHYSIOLOGY-PARIS. 72-72. 1998
- Regulation of isolated pancreatic beta-cell signalling system by 17 beta-oestradiol. JOURNAL OF PHYSIOLOGY-PARIS. 90-90. 1998
chapter
- Toxic Effects of Common Environmental Pollutants in Pancreatic b-Cellsand the Onset of Diabetes Mellitus. Encyclopedia of Endocrine Diseases2nd Edition. 764-775. 2019
- Toxic Effects of Common Environmental Pollutants in Pancreatic b-Cellsand the Onset of Diabetes Mellitus. Encyclopedia of Endocrine Diseases. 765-775. 2018
- Fetal and Adult Esposure to Bisphenol-A as a Contributing Factor in the Etiology of the Metabolic Syndrome. Multi-System Endocrine Disruption. 113-126. 2011
- Disrupción endocrina por xenoestrógenos. Fraudes, Mitos y Realidades en Alimentación y Nutrición. 43-58. 2007
- Regulación por glucosa de la función de las células alfa, beta y delta en el islote de Langerhans. El islote pancreático en el desarrollo y tratamiento de la diabetes.. 19-32. 2007
- Receptores de estrógenos de membrana. Actualidad en la atención al climaterio y menopausia. 191-192. 2006
- Characteristics of a nonclassical membrane estrogen receptors in the endocrine pancreas. The identities of membrane steroid receptors. 160-176. 2003
- Efectos rápidos de los xenoestrógenos por unión a un receptor en la membrana plasmática.. Nutrición clínica y dietética hospitalaria.. 234-234. 2001
- Oscilaciones de calcio intracelular y liberación de OSC-Espondina en el órgano subcomisural bovino en cultivo.. Avances en endocrinología comparada.. 134-138. 2001
- Efectos no genómicos del 17- beta estradiol en el islote de Langerhans. Neurobiología, una visión clínica y experimental.. 77-82. 2000
- El papel de la albúmina como mensajero extracelular.. Neurobiología, una visión clínica y experimental.. 2000
- Imaging intracellular calcium in living tissue by laser- scanning confocal microscope. Calcium. The molecular basis of calcium action in biology and medicine. 2000
- Glucose metabolism regulates cytosolic Ca2+ in the pancreatic Beta-cell by three different mechanisms. Physiology and Pathophysiology of the islets of Langerhans. 235-243. 1998
congress communication
patent
- Use of beta-estradiol (I) and its analogs and derivatives for treatment of diabetes mellitus

presentations

invited conference
- Metabolism Disruptors, Conferencia 2024
- Role of Endocrine Disruptors in Plastics in the Etiology of Type-2 Diabetes, Conferencia 2024
- Plastics and ß-cell plasticity, Conferencia 2024
- How do endocrine disruptors upset beta cells and contribute to diabetes?, Conferencia 2024
- Introducing Endocrine Disruptors and their Identification, Conferencia 2024
- Bisphenol-A Signaling Through the Estrogen Receptor ERß Outside the Nucleus, Conferencia 2024
- Plastics and Plasticity of Pancreatic beta cells, Conferencia 2023
- Altered beta cell physiology and risk of diabetes from endocrine disrupting chemicals, Conferencia 2023
- Identifying the effects of endocrine disruptors in human health, Conferencia 2023
- Endocrine-Disrupting Chemicals and metabolic diseases, Conferencia 2023
- How do endocrine disruptors upset our metabolic system?, Conferencia 2023
- Disruptors endocrins i diabetis, Conferencia 2023
- Efecto de los disruptores endocrinos sobre la función alfa y beta pancreática, Conferencia 2023
- Alteración de la masa funcional de la célula beta pancreática por disruptores endocrinos, Conferencia 2023
- Papel de los receptores de estrógenos y de los disruptores endocrinos en la diabetes, Conferencia 2022
- Identification of endocrine disruptors with diabetogenic activity using pancreatic beta cells, Conferencia 2022
- Endocrine disruptors and beta cells , Conferencia 2022
- Endocrine disruptors as environmental determinants of diabetes mellitus, Conferencia 2022
- Endocrine disruptors and pancreatic beta cells, Conferencia 2022
- Disruptores Endocrinos , Conferencia 2021
- New hazard classes for endocrine disruptors in CLP, Conferencia 2021
- the role of scientists in influencing public decision and their interaction with policy makers, Conferencia 2021
- Disruptores endocrinos: ¿A dónde vamos?, Conferencia 2020
- Endocrine Disrupting Chemicals in the Aetiology of Diabetes, Conferencia 2019
- EDC disturbance of beta-cells and risk of diabetes, Conferencia 2019
- Unconventional actions of environmental estrogens via estrogen receptors, Conferencia 2019
- The role of Endocrine Disrupting Chemicals in the etiology of Diabetes Mellitus, Conferencia 2019
- Endocrine Disrupting Chemicals and Diabetes Mellitus, Conferencia 2019
- Bisphenol-A modulates ion channel expression and function via estrogen receptor ß in mouse pancreatic beta cells, Conferencia 2019
- Endocrine-Disrupting Chemicals, Conferencia 2018
- Exposure to endocrine disrupting chemicals during pregnancy and risk of obesity in the offspring, Conferencia 2018
- Discussion Leader EED Toxicology and Modes of Action: Mechanisms of Inheritence and Novel Paradigms, Conferencia 2018
- Disruptores metabólicos y obesidad, Conferencia 2017
- Prestentation of comments on behalf of the Endocrine Society (USA), Conferencia 2017
- ¿QUE PROVOVA LA DIABETES? AUTODESTRUCCION O TOXICIDAD?, Conferencia 2017
- Panel of experts, Conferencia 2017
- Panel of experts, Conferencia 2017
- Exposure to endocrine disrupting chemicals during pregnancy and risk of diabetes in dams and off spring, Conferencia 2016
- EFECTO SOBRE LA CÉLULA BETA PANCREÁTICA DE LA EXPOSICIÓN DURANTE EL EMBARAZO A DISRUPTORES ENDOCRINOS, Conferencia 2016
- Disruptores Endocrinos en la Génesis de la Obesidad, Conferencia 2015
- Type 2 diabetes and EEDs : from experimental models to clinical epidemiology., Conferencia 2015
- Low doses of bisphenol-A and adiposity, Conferencia 2015
- Papel de los disruptores endocrinos en la Diabetes Mellitus y la obesidad., Conferencia 2015
- Bisphenol A a Diabesogen? Timing of Exposure as a Predictor of Diabesity, Conferencia 2015
- Evidencias experimentales del efecto de los contaminantes ambientales persistentes, Conferencia 2015
- Endocrine Disruptors and Diabetes Susceptibility, Conferencia 2015
- Endocrine disruptors: New environmental causes of diabetes and obesity , Conferencia 2014
- Is BPA a weak estrogen?, Conferencia 2014
- Receptores de estrógenos (ER) y diabetes, Conferencia 2014
- Is Bisphenol-A a Diabesogen? Timing of Exposure as a Predictor of Diabesity, Conferencia 2014
- Role of Endocrine Disruptors in the Etiology of Type 2 Diabetes, Conferencia 2013
- Timing of Bisphenol-A Exposure, Conferencia 2013
- Disruptores endocrinos y diabesidad, Conferencia 2013
- El Bisfenol-A durante la preñez en ratones altera la función y la masa de célula beta pancreática en la descendencia, Conferencia 2013
- Endocrine Disrutors as risk factor for type 2 diabetes, Conferencia 2013
- TIMING OF DEVELOPMENTAL BISFENOL-A EXPOSURE AS PREDICTOR OF DIABETES DEVELOPMENT, Conferencia 2013
- Antidiabetic actions of estrogen receptor beta agonists, Conferencia 2013
- Endocrine disruptors as risk factor for type 2 diabetes, Conferencia 2013
- TIMING OF DEVELOPMENTAL BISFENOL-A EXPOSURE AS PREDICTOR OF DIABETES DEVELOPMENT, Conferencia 2013
- "TIMING OF DEVELOPMENTAL BISFENOL-A EXPOSURE AS PREDICTOR OF DIABETES DEVELOPMENT", Conferencia 2013
- Endocrine Disruptors as risk factor for type 2 diabetes, Conferencia 2013
- Endocrine Disruptors as risk factor for type 2 diabetes, Conferencia 2013
- Oestrogen receptor beta: a new target for type 2 diabetes treatment, Conferencia 2013
- ENDOCRINE DISCRUPTORS AS RISK FACTOR FOR TYPE 2 DIABETES, Conferencia 2013
- PARTICIPAÇÃO DOS HORMÔNIOS ESTROGÊNIOS SOBRE O MECANISMO DE SECREÇÃO DE INSULINA, Conferencia 2013
- Papel do BPA na regulaçao glicêmica, Conferencia 2012
- Efecto antidiabetogénico de los agonistas del receptor de estrógenos beta, Conferencia 2012
- Bisphenol-A in the etiology of type-2 diabetes, Conferencia 2012
- Bisphenol-A dirsupts pancreatic beta cell funtion and produces insulin resitance: implications for type 2 diabetes, Conferencia 2012
- Hazard assesment of EDCs. Asistencia en calidad de experto, Conferencia 2012
- Timing of Developmental BPA Exposure as Predictor of Diabetes, Conferencia 2012
- Science and the precautionary principle ¿ lessons for preventing harm, Conferencia 2012
- Endocrine disruptors and glucose metabolism/diabetes, Conferencia 2012
- Impact of Insulin Resistance on Beta-Cell Function ¿ Clinical Studies (chairman), Conferencia 2012
- Role of estrogens in glucose control, Conferencia 2011
- Bisphenol A as a Risk Factor for Type II Diabetes , Conferencia 2011
- The pancreatic beta cell as a traget of estrogens and xenoestrogens, Conferencia 2011
- Disruptores endocrinos en la etiologia de la diabetes, Conferencia 2011
- Bisphenol-A and Diabetes, Conferencia 2011
- Bisphenol-A as a risk factor for type 2 diabetes, Conferencia 2010
- BPA in the etiology of type-2 diabetes, Conferencia 2010
- Regulation of ATP-sensitive potassium channel activity by, Conferencia 2010
- Non-classical actions of oestrogens in pancreas , Conferencia 2010
- Bisphenol-A: a new risk factor for type-2 diabetes, Conferencia 2009
- The role of estrogen receptors in pancreatic ¿-cell function: Implications for blood glucose homeostasis and diabetes, Conferencia 2009
- Novel oestrogenic effects on pancreatic beta cell function, Conferencia 2009
- Novel estrogenic effect on pancreatic beta cell function, Conferencia 2009
- Diabetes from plastic? Bisphenol-a affects pancreatic function, Conferencia 2009
- Bisphenol-A disrupts pancreatic beta cell function and blood glucose homeostasis, Conferencia 2008
- Diabetes from plastic? Bisphenol-A affects endocrine pancreatic function, Conferencia 2008
- Xenoestrógenos y Diabetes, Conferencia 2008
- Role of estrogen receptors in pancreatic beta cell function, Conferencia 2007
- Rapid estrogen and xenoestrogen effects in pancreatic beta cell function, Conferencia 2007
- The endocannabinoid system and the endocrine pancreas: role in the regulation of glucagon and insulin secretion, Conferencia 2007
- Effects of endocrine disruptors on pancreatic function , Conferencia 2007
- regulación de la función de la célila beta pancreática por el receptor de estrógenos ERalfa, Conferencia 2007
- Regulation of pancreatic beta cell function by classic and non-classic estrogen receptors, Conferencia 2007
- BISPHENOL-A CONFERENCE. PANEL EXPERTS. NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES (NIEHS)., Conferencia 2006
- XXIX CONGRESO DE LA SOCIEDAD ESPAÑOLA DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR. REUNIÓN GRUPO DE REGULACIÓN METABÓLICA. , Conferencia 2006
- THE INTERNATIONAL SYMPOSIUM ON HYPERTENSION, Conferencia 2006
- Gordon research Conference, Conferencia 2006
- XVII INTERNATIONAL SYMPOSIUM OF THE JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, Conferencia 2006
- Post EASD Symposium 2005, Conferencia 2005
- VII Conferencia sobre disruptores endocrinos, Conferencia 2005
- Rapid actions of 17beta-estradiol on the endocrine pancreas, Conferencia 2005
- Fourth International Meeting on Rapid Responses to Steroid Hormones , Conferencia 2005
- Sesión inaugural de curso de doctorado de envejecimiento, Conferencia 2005
- Acciones rápidas de los estrógenos endógenos y ambientales sobre el páncreas endocrino, Conferencia 2005
- The action of endocrine disruptors in pancreatic alfa and beta cells, Conferencia 2004
- Utilización de la microscopia confocal en la fisiología endocrina, Conferencia 2004
- Nuevas vías de acción de los estrógenos en el páncreas endocrino, Conferencia 2004
- Mecanismes d'acció alternatius de l'estradiol, Conferencia 2004
- Nuevos mecanismos de acción. El ejemplo del Bisfenol-A. VI Conferencia Nacional sobre Disruptores Endocrinos., Conferencia 2003
- New Insights in Xenoestrogen Actions: From Plasma Membrane to Nuclear Function. e.hormone2003., Conferencia 2003
- Microscòpia Confocal. Curs de tècniques de Fisiologia Cel·lular., Conferencia 2003
- Plasma Membrane Estrogen Receptor in the endocrine pancreas. III International Meeting Rapid Responses to Steroids Hormones., Conferencia 2003
- I Jornada sobreMitos, Fraudes y Realidades en Alimentación y Nutrición., Conferencia 2003
- Regulation of Mouse beta cell signaling system by estrogens. XXXII Meeting of the Spanish Physiologica Society. Joint Meeting with The Physiological Society of Great Britain , Conferencia 2003
- Regulación rápida de la señalización celular por estradiol en la célula beta pancreática, Conferencia 2003
- L`inici del grup de recerca: un obstacle insalvable?Mesa redonda en la sesión conmemorativa del 90 aniversario de la Societat Catalana de Biología., Conferencia
- Disruptores endocrinos, Conferencia
- La señal de calcio intracelular en las células alfa, beta y delta del islote de Langerhans., Conferencia
- Nuevas vías de señalización para los estrógenos., Conferencia
- Regulación de la señalización celular por 17beta-estradiol a través de un receptor de estrógenos en la membrana, Conferencia
- Regulación rápida de la señalización celular por 17 -estradiol a través de un receptor de membranaSeminarioInstituto de Biología y Genética Molecular, Conferencia

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NADAL NAVAJAS, ANGEL

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