Publicaciones en VIVO

Mapa de la ciencia

Red de Coinvestigador

POVEDA LARROSA, JOSE ANTONIO

Person (Active)

Positions

Profesor/a Titular Universidad, Agroquímica y Medio Ambiente 2014 -
PDI INVESTIGADOR, Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2018 -
MIEMBRO, Relaciones Estructura-función en Proteínas de Membrana 2012 -
PDI INVESTIGADOR, Instituto de Biología Molecular y Celular 2004 - 2018
Profesor/a Contratado/a Doctor/a, Agroquímica y Medio Ambiente 2008 - 2014
Profesor/a Colaborador/a, Agroquímica y Medio Ambiente 2005 - 2007
Ayudante de Escuela Universit., Agroquímica y Medio Ambiente 2001 - 2005
FPI-MINISTERIO, Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 1998 - 2001

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supported publications or other works

selected publications

academic article
- Anionic Phospholipids Shift the Conformational Equilibrium of the Selectivity Filter in the KcsA Channel to the Conductive Conformation: Predicted Consequences on Inactivation. BIOMEDICINES. 1376-1394. 2023
- Modulation of Cholesterol Pathways in Human Macrophages Infected by Clinical Isolates of Leishmania infantum. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 878711-878723. 2022
- Molecular Events behind the Selectivity and Inactivation Properties of Model NaK-Derived Ion Channels. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 1-22. 2022
- Silica/Proteoliposomal Nanocomposite as a Potential Platform for Ion Channel Studies. BIOMOLECULES. 1-15. 2022
- Probing the Structural Dynamics of the Activation Gate of KcsA Using Homo-FRET Measurements. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 1-22. 2021
- Tetraoctylammonium, a Long Chain Quaternary Ammonium Blocker, Promotes a Noncollapsed, Resting-Like Inactivated State in KcsA. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 490-510. 2021
- Modulation of Function, Structure and Clustering of K + Channels by Lipids: Lessons Learnt from KcsA. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2554. 2020
- Accessibility of Cations to the Selectivity Filter of Kcsa in the Inactivated State: An Equilibrium Binding Study. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 669-689. 2019
- Antiviral Activity of a Turbot (Scophthalmus maximus) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion. MARINE DRUGS. 2019
- Homo-FRET studies of potassium channel KcsA: a closer look to selectivity filter dynamics and regulation. SCIENTIFIC REPORTS. 6215-6227. 2019
- Modulation of the KcsA potassium channel by anionic phospholipids: Role of the non-annular arginines. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 183029-183043. 2019
- Differential binding of monovalent cations to KcsA: Deciphering the mechanisms of potassium channel selectivity. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 779-788. 2017
- Selective exclusion and selective binding both contribute to ion selectivity in KcsA, a model potassium channel. JOURNAL OF BIOLOGICAL CHEMISTRY. 15552-15560. 2017
- Towards understanding the molecular basis of ion channel modulation by lipids: Mechanistic models and current paradigms. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1507-1516. 2017
- Competing Lipid-Protein and Protein-Protein Interactions Determine Clustering and Gating Patterns in KcsA. JOURNAL OF BIOLOGICAL CHEMISTRY. 1-15. 2015
- Experimental resistance to drug combinations in Leishmania donovani: metabolic and phenotypic adaptations. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2242-2255. 2015
- Lipid modulation of ion channels through specific binding sites.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1560-1567. 2014
- Detergent-labile, supramolecular assemblies of KcsA: relative abundance and interactions involved. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 193-200. 2013
- Contribution of ion binding affinity to ion selectivity and permeation in KcsA, a model potassium channel.. BIOCHEMISTRY. 3891-3900. 2012
- Immobilization and characterization of giant unilamellar vesicles (GUVs) within porous silica glasses. SOFT MATTER. 408-417. 2012
- Functional Reconstitution of a Voltage-Gated Potassium Channel in Giant Unilamellar Vesicles. PLOS ONE. 25529. 2011
- Uptake of the antileishmania drug tafenoquine follows a sterol-dependent diffusion process in Leishmania.. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2562-2565. 2011
- Ion binding to KcsA: implications in ion selectivity and channel gating. BIOCHEMISTRY. 9480-9487. 2010
- Occupancy of non-annular lipid Binding sites on kcsA greatly increases the stability of the tetrameric protein. . BIOCHEMISTRY. 5397-5404. 2010
- Biophysical and functional characterization of an ion channel peptide confined in a sol-gel matrix.. JOURNAL OF PHYSICAL CHEMISTRY B. 7534-7540. 2009
- : Protein self-assembly and lipid binding in the folding of the potassium channel KcsA.. BIOCHEMISTRY. 2123-2133. 2008
- N-type inactivation of the potassium channel KcsA by the Shaker B "ball" peptide: mapping the inactivating peptide-binding epitope.. JOURNAL OF BIOLOGICAL CHEMISTRY. 18076-18085. 2008
- Protein-promoted membrane domains.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1583-1590. 2008
- Dynamics of tryptophan in the histidine-containing phosphocarrier protein of Streptomyces coelicolor: evidence of multistate equilibrium unfolding. BIOCHEMISTRY. 7252-7260. 2007
- Antifungal effects and mechanism of action of viscotoxin A3. EUROPEAN JOURNAL OF BIOCHEMISTRY. 72-83. 2006
- Clustering and Coupled Gating Modulate the Activity in KcsA, a Potassium Channel Model. JOURNAL OF BIOLOGICAL CHEMISTRY. 18837-18848. 2006
- Effects of conducting and blocking ions on the structure and stability of the potassium channel kcsa.. JOURNAL OF BIOLOGICAL CHEMISTRY. 29905-29915. 2006
- Nicotinic acetylcholine receptor properties are modulated by the surrounding lipids: an ¿in vivo¿ study. JOURNAL OF MOLECULAR NEUROSCIENCE. 5-6. 2006
- Non-uniform membrane probe distribution in resonance energy transfer: application to protein-lipid selectivity. JOURNAL OF FLUORESCENCE. 161-172. 2006
- Structural and functional changes induced in the nicotinic acetylcholine receptor by membrane phospholipids. JOURNAL OF MOLECULAR NEUROSCIENCE. 121-124. 2006
- The influence of a membrane environment on the structure and stability of a prokaryotic potassium channel, KcsA. FEBS LETTERS. 5199-5204. 2005
- Unfolding and Refolding in Vitro of a Tetrameric, alpha-Helical Membrane Protein: The Prokaryotic Potassium Channel KcsA. BIOCHEMISTRY. 14344-14352. 2005
- Binding of the C-terminal Sterile {alpha} Motif (SAM) Domain of Human p73 to Lipid Membranes. JOURNAL OF BIOLOGICAL CHEMISTRY. 46878-46885. 2003
- Intrinsic Tyrosine fluorescence as a tool to study the interaction of the Shaker B ball peptide with anionic membranes. BIOCHEMISTRY. 7124-7132. 2003
- Probing The Channel-Bound Shaker B Inactivating Peptide By Stereoisomeric Substitution At A Strategic Tyrosine Residue.. BIOCHEMISTRY. 8879-8884. 2003
- Segregation of phosphatidic acid-rich domains in reconstituted acetylcholine receptor membranes. BIOCHEMISTRY. 12253-12262. 2002
- Tyrosine Phosphorylation of the Inactivating Peptide of the Shaker B Potassium Channel: A Structural-Functional Correlate.. BIOCHEMISTRY. 12263-12269. 2002
chapter
- Immobilization and characterization of the transmembrane ion channel peptide gramicidin in a sol-gel matrix. Bioengineered and Bioinspired Systems III . 111-118. 2007
- Structural and functional modulation of ion channels by specific lipids: from model systems to cell membranes. . Protein-lipid interactions. 203-233. 2006
- Segregation of phosphatidic acid-rich domains in reconstituted acetylcholine receptor membranes. Cholinergic Mechanisms: Function and Dysfunction. 665-669. 2004
- The segregation of a lipid domain underlies structural and functional modulation of acetylcholine receptor in reconstituted membranes. Xth international symposium on cholinergic mechanisms. From Torpedo electric organ to human brain: fundamental and applied aspects.. 432-433. 1998
- Lipid-protein interactions in reconstituted membranes containing nicotinicacetylcholine receptor . Spectroscopy of Biological Molecules: Modern Trends. 339-340. 1997
congress communication

presentations

invited conference
- Conformational plasticity of the potassium channel KcsA: lipid and ion modulation, Conferencia 2022
- Conformational plasticity of ion channels: a fluorescence-based approach, Conferencia 2022
- On the molecular basis of ion channel selectivity and conduction, Conferencia 2009
- XXVII congreso dela SEBBM, Conferencia 2004