Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2020
2020
Institute
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Publications
Research Report
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academic article
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Synthesis of a library of 3-oxopiperazinium and perhydro-3-oxo-1,4-diazepinium derivatives and identification of bioactive compounds.
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Risk of Cancer in Family Members of Patients with Lynch-Like Syndrome
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A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration
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A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability
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A small dose of intraarticular triamcinolone plus mepivacaine provides a rapid and sustained relief for gout flares.
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A sustainable amperometric biosensor for the analysis of ascorbic, benzoic, gallic and kojic acids through catechol detection. Innovation and signal processing
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Aggregation of 25-hydroxycholesterol in a complex biomembrane. Differences with cholesterol
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Antioxidant supplementation modulates neutrophil inflammatory response to exercise-induced stress
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Antioxidants and Skin Protection
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Autophagy-inducing peptides from mammalian VSV and fish VHSV rhabdoviral G glycoproteins (G) as models for the development of new therapeutic molecules.
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Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients.
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Beta-glucan enhances the response to SVCV infection in zebrafish.
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Bisphenol-A exposure during pregnancy alters pancreatic ß-cell division and mass in male mice offspring: A role for ERß
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Bisphenol-S and Bisphenol-F alter mouse pancreatic ß-cell ion channel expression and activity and insulin release through an estrogen receptor ERß mediated pathway
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CLytA-DAAO, Free and Immobilized in Magnetic Nanoparticles, Induces Cell Death in Human Cancer Cells
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Calorie restriction improves physical performance and modulates the antioxidant and inflammatory responses to acute exercise
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Carotenoids from persimmon juice processing
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Competitive inhibition of protein adsorption to silica surfaces by their coating with high density charge polyelectrolytes
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Concrete perturbation in a 13-year in situ concrete/bentonite interaction from FEBEX experiments. New insight of 2:1 Mg phyllosilicate precipitation at the interface
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Developmental profile of SK2 channel expression and function in CA1 neurons.
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Diagnostic yield of early repeat colonoscopy after suboptimal bowel preparation in a fecal immunochemical test-based screening program
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Differential Effects of IGF-1R Small Molecule Tyrosine Kinase Inhibitors BMS-754807 and OSI-906 on Human Cancer Cell Lines
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Disease-modifying effects of natural ¿9-tetrahydrocannabinol in endometriosis-associated pain
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Early stimulation of TREK channel transcription and activity induced by Oxaliplatin-dependent cytosolic acidification.
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Enhanced recovery after low- and medium-risk liver transplantation. A single-center prospective observational cohort study
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Exploration of TRPM8 Binding Sites by Carboline-based Antagonists and Their In Vitro Characterization and in Vivo Analgesic Activities
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Fluorene-Based Donor-Acceptor Copolymers Containing Functionalized Benzotriazole Units: Tunable Emission and their Electrical Properties
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Functionality of beta- adrenergic receptors in patients with cirrhosis treated chronically with non- selective beta-blockers.
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Grupo de Innovación Docente en el Grado de Biotecnología
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Highly functionalized ß-lactams and 2-ketopiperazines as TRPM8 antagonists with antitumor and antiallodynic activity.
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Human importin ¿3 and its N-terminal truncated form, without the importin-ß-binding domain, are oligomeric species with a low conformational stability in solution
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Identification of the phospholipid binding regions of the envelope E protein of flaviviruses by molecular dynamics.
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Impacts of food contact chemicals on human health: a consensus statement
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Improving a Natural Compound: Design of Innovative Neurocosmeceuticals for Sensitive Skin
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Increasing Versatility of the DNA Vaccines through Modification of the Subcellular Location of Plasmid-Encoded Antigen Expression in the In Vivo Transfected Cells.
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Industrial-Scale Study of the Chemical Composition of Olive Oil Process-Derived Matrices
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Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses
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Integrative Strategy of Testing Systems for Identification of Endocrine Disruptors Inducing Metabolic Disorders¿An Introduction to the OBERON Project
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Intrinsically disordered proteins in biology: One for all, all for one.
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Investigational drugs in early phase clinical trials targeting thermotransient receptor potential (thermoTRP) channels
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Liver Sinusoidal Endothelial Cells Contribute to Hepatic Antigen-Presenting Cell Function and Th17 Expansion in Cirrhosis.
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Location, Orientation and Aggregation of Bardoxolone-ME, CDDO-ME, in a Complex Phospholipid Bilayer Membrane
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Moduladores del termorreceptor TRPV1 desactivables metabólicamente en la farmacología
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Modulation of Function, Structure and Clustering of K + Channels by Lipids: Lessons Learnt from KcsA
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Morphological and functional adaptations of pancreatic alpha-cells during late pregnancy in the mouse
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Mu and delta opioid receptors play opposite nociceptive and behavioural roles on nerve-injured mice
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Nanomaterials: Applications in Food, Environmental Remediation, and Bioengineering
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Neutralization of viral infectivity by zebrafish c-reactive protein isoforms.
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New Synthesis of Mannoside Containing Neoglycoconjugates by Reaction of Propargyl Mannosides with Polyalkylcarboxylated Scaffolds
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PH-dependent solution structure and activity of a reduced form of the host-defense peptide myticin C (Myt C) from the mussel mytilus galloprovincialis
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Physico-Chemically Distinct Nanomaterials Synthesized from Derivates of a Poly(Anhydride) Diversify the Spectrum of Loadable Antibiotics
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Postprandial Lipemia Modulates Pancreatic Alpha-Cell Function in the Prediction of Type 2 Diabetes Development: The CORDIOPREV Study
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Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2¿-O-Methylation of Viral RNA
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Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain.
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Quercetin metabolites from Hibiscus sabdariffa contribute to alleviate glucolipotoxicity-induced metabolic stress in vitro
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Regional expression and subcellular localization of the voltage-gated calcium channel ß subunits in the developing mouse brain
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Restricted replication of viral hemorrhagic septicemia virus (VHSV) in a birnavirus-carrier cell culture
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Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity
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Rosemary Diterpenes and Flavanone Aglycones Provide Improved Genoprotection against UV-Induced DNA Damage in a Human Skin Cell Model
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Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients
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Structure and functionalities of the human c-reactive protein compared to the zebrafish multigene family of c-reactive-like proteins.
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Surgical Induction of Endometriosis in Female Mice
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Sweet Cherry Byproducts Processed by Green Extraction Techniques as a Source of Bioactive Compounds with Antiaging Properties
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Tackling Antibiotic Resistance with Compounds of Natural Origin: A Comprehensive Review
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Targeting thermoTRP ion channels: in silico preclinical approaches and opportunities
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The Beneficial Effects of Lippia Citriodora Extract on Diet-Induced Obesity in Mice Are Associated with Modulation in the Gut Microbiota Composition
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The Commonly Overlooked Factor. Commentary on: ¿Environmental Obesogens and their Impact on Susceptibility to Obesity¿
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The Emerging Relevance of AIM2 in Liver Disease.
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The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds
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The Interaction of Temozolomide with Blood Components Suggests the Potential Use of Human Serum Albumin as a Biomimetic Carrier for the Drug
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The antimicrobial capacity of Cistus salviifolius and Punica granatum plant extracts against clinical pathogens is related to their polyphenolic composition.
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The endocannabinoid system in modulating fear, anxiety and stress
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The isolated armadillo-repeat domain of Plakophilin 1 is a monomer in solution with a low conformational stability
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Trafficking of ThermoTRP Channels.
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Variation in Colonoscopy Performance Measures According to Procedure Indication
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Zebra fish lacking adaptive immunity acquire an antiviral alert state characterized by upregulated gene expression of apoptosis, multigene families, and interferon-related genes.
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Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol -
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he LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes.
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book
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chapter
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congress communication
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external project
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hiring
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invited conference
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operating licence
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person
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AL ABDULLA , RUBA
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ALARCON ALARCON, DAVID
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ALMAGRO RUZ, LUCIA
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BABILONI CHUST, IGNACIO
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BALLESTA PAYA, JUAN JOSE
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BOIX CASTEJON, MARINA
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BUTRON GARCIA, LAURA
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DIAZ RUIZ, CLAUDIA
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FALCO GRACIA, JUAN ALBERTO
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FERRANDIZ HUERTAS, CLOTILDE
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GIORGI , SIMONA
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LOZANO RUIZ, BEATRIZ
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LUCAS MAÑOGIL, EFREN
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MEDINA PERIS, ALICIA
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OSUNA TENORIO, GEMA
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PALACIOS RODRIGUEZ, CRISTINA
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PASCUAL MARTINEZ, ROBERTO
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PEREZ SANCHEZ, ALMUDENA
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RENART PEREZ, MARIA LOURDES
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RODRIGUEZ CAÑAS, ENRIQUE
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person (active)
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ALACID MARTINEZ, YOLANDA INMACULADA
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ALONSO MAGDALENA, PALOMA
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ALVAREZ MARTINEZ, FRANCISCO JAVIER
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BARRAJON CATALAN, ENRIQUE
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BONMATI BOTELLA, BEATRIZ
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CABAÑERO FERRI, DAVID
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CHICO GRAS, VERONICA
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DE ANDRES LOPEZ, JORGE
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ENCINAR HIDALGO, JOSÉ ANTONIO
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ESQUEMBRE TOME, ROCIO
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FERNANDEZ ESCAMILLA, ANA MARIA
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FERNÁNDEZ BALLESTER, GREGORIO JOAQUIN
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FERNÁNDEZ CARVAJAL, ASIA
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FERRER MONTIEL, ANTONIO VICENTE
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FUENTES MARHUENDA, ESTHER TERESA
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GARCIA HEREDIA, ANABEL
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GARCIA QUINTANILLA, CELIA
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GIUDICI BESSEGHINI, ANA MARCELA
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GOMEZ PEREZ, FRANCISCO JAVIER
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GONZALEZ NAVAJAS, JOSE MANUEL
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GONZALEZ ROS, JOSE MANUEL
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HERRANZ LOPEZ, MARIA DOLORES
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LOSADA ECHEBERRIA, MARIA
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MALLAVIA MARIN, RICARDO
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MARROQUI ESCLAPEZ, LAURA
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MARTI BRUÑA, NURIA
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MARTINEZ GODFREY, JESICA
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MARTINEZ TOME, MARIA JOSE
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MATEO MARTÍNEZ, CARMEN REYES
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MEDINA GALI, REGLA MARIA
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MICOL MOLINA, VICENTE
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NADAL NAVAJAS, ANGEL
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NEIRA FALEIRO, JOSE LUIS
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OLIVARES VICENTE, MARIA DOLORES
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ORTEGA-VILLAIZAN ROMO, MARIA DEL MAR
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PEREZ GARCIA-ESTAÑ, LUIS
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PEREZ SERNA, ATENEA ALEXANDRA
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POVEDA LARROSA, JOSE ANTONIO
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QUESADA MOLL, IVAN
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RIPOLL ORTS, CRISTINA
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RUBIO CAMACHO, MARTA
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RUIZ TORRES, VERONICA
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SACEDA SANCHEZ, MIGUEL
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SALVADOR MIRA, MARIA ELIZABHET
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SANCHEZ MARZO, NOELIA
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SAURA LOPEZ, DOMINGO
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SOUSA DOS SANTOS, REINALDO
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TORRES MONTERO, MARIA REMEDIOS
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VALERO ROCHE, MANUEL
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VILLALAIN BOULLON, JOSÉ
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VILLALBA RIQUELME, EVA MARIA
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ZAPATER HERNANDEZ, PEDRO
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research project
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startup
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technological support
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thesis
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thrid party project
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