Research Report
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academic article
- Antiviral Activity of a Turbot (Scophthalmus maximus) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion.
- 1¿(2¿,5¿-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1- propanone (RGM079): A Positive Allosteric Modulator of ¿7 Nicotinic Receptors with Analgesic and Neuroprotective Activity
- A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration.
- A group II intron-encoded protein interacts with the cellular replicative machinery through the ß-sliding clamp.
- A positive allosteric modulator of alpha7 nicotinic receptors with analgesic and neuroprotective activity.
- Accessibility of Cations to the Selectivity Filter of Kcsa in the Inactivated State: An Equilibrium Binding Study
- Actual Anti-TNF Trough Levels Relate to Serum IL-10 in Drug-Responding Patients With Crohn's Disease.
- Acute phase protein response to viral infection and vaccination
- Algunas enseñanzas sobre dinámica de poblaciones. La expansión del arruí y la cabra montés en la Región de Murcia
- Antioxidant and Photoprotective Activity of Apigenin and its Potassium Salt Derivative in Human Keratinocytes and Absorption in Caco-2 Cell Monolayers
- Antiviral Activity of a Turbot (Scophthalmus maximus) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion
- Bacterial DNA translocation contributes to systemic inflammation and to minor changes in the clinical outcome of liver transplantation
- Bacterial DNA translocation contributes to systemic inflammation and to minor changes in the clinical outcome of liver transplantation.
- Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception
- Chromatin immunoprecipitation and high throughput sequencing of SVCV-infected zebrafish reveals novel epigenetic histone methylation patterns involved in antiviral immune response.
- Circulating levels of butyrate are inversely related to portal hypertension, endotoxemia, and systemic inflammation in patients with cirrhosis.
- Dendrimers as Competitors of Protein-Protein Interactions of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1
- Determinants of Severity in Acute Pancreatitis
- Development of a New Delivery System Based on Drug-Loadable Electrospun Nanofibers for Psoriasis Treatment
- Differential effects of a combination of Hibiscus sabdariffa and Lippia citriodora polyphenols in overweight/obese subjects: A randomized controlled trial
- Editorial: Endocrine Disrupters and Metabolism
- Epigallocatechin-3-gallate location and interaction with late endosomal and plasma membrane model membranes by molecular dynamics.
- Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A.
- Fish Red Blood Cells Modulate Immune Genes in Response to Bacterial Inclusion Bodies Made of TNF¿ and a G-VHSV Fragment
- Glutathione-dependent enzyme activities of peripheral blood mononuclear cells decrease during the winter season compared with the summer in normal-weight and severely obese adolescents
- Homo-FRET studies of potassium channel KcsA: a closer look to selectivity filter dynamics and regulation
- Hydroxycholesterol binds and enhances the anti-viral activities of zebrafish monomeric c-reactive protein isoforms
- IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells.
- Improved hemodynamic and liver function in portal hypertensive cirrhotic rats after administration of B. pseudocatenulatum CECT 7765.
- In utero exposure to bisphenol-A disrupts key elements of retinoid system in male mice offspring
- Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets
- Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers.
- Is TRPA1 Burning Down TRPV1 as Druggable Target for the Treatment of Chronic Pain?
- Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis.
- Marine Invertebrate Extracts Induce Colon Cancer Cell Death via ROS-Mediated DNA Oxidative Damage and Mitochondrial Impairment
- Mechanisms of blockade of the muscle-type nicotinic receptor by benzocaine, a permanently uncharged local anesthetic
- Metabolomic analysis of the effects of a commercial complex biostimulant on pepper crops
- Modulation of the KcsA potassium channel by anionic phospholipids: Role of the non-annular arginines
- Natural Compounds as New Cancer Treatments
- Oestrogen receptor ß mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells
- Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain.
- Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes
- Plasma proteomic analysis of zebrafish following spring viremia of carp virus infection
- Plasma proteomic analysis of zebrafish following spring viremia of carp virus infection,
- Polyfluorene-Based Multicolor Fluorescent Nanoparticles Activated by Temperature for Bioimaging and Drug Delivery
- Potential Role of Rainbow Trout Erythrocytes as Mediators in the Immune Response Induced by a DNA Vaccine in Fish.
- Preclinical evaluation of the antimicrobial-immunomodulatory dual action of xenohormetic molecules against Haemophilus influenzae respiratory infection
- Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress.
- Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers.
- Relationships Between Chemical Structure and Antioxidant Activity of Isolated Phytocompounds from Lemon Verbena
- Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity.
- Revisiting silibinin as a novobiocin-like Hsp90¿C-terminal inhibitor: Computational modeling and experimental validation.
- Single versus double expewrimental bile duct ligation model for inducing bacterial translocation
- Structure-based design of novel biphenyl amide antagonists of human Transient Receptor Potential Cation Channel Subfamily M Member 8 channels (TRPM8) with potential implications in the treatment of sensory neuropathies.
- The C-terminal SAM domain of p73 binds to the N terminus of MDM2.
- The Megalocytivirus RBIV Induces Apoptosis and MHC Class I Presentation in Rock Bream (Oplegnathus fasciatus) Red Blood Cells
- The Potential Synergistic Modulation of AMPK by Lippia citriodora Compounds as a Target in Metabolic Disorders
- The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3
- The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase.
- The metabolic and vascular protective effects of olive (Olea europaea L.) leaf extract in diet-induced obesity in mice are related to the amelioration of gut microbiota dysbiosis and to its immunomodulatory properties.
- The prebiotic properties of Hibiscus sabdariffa extract contribute to the beneficial effects in diet-induced obesity in mice
- Turbot (Scophthalmus maximus) Nk-lysin induces protection against the pathogenic parasite Philasterides dicentrarchi via membrane disruption.
- Update on Activities in Endocrine Disruptor Research and Policy
- Viral interference between infectious pancreatic necrosis virus and spring viremia of carp virus in zebrafish
- Vitamin C loss kinetics and shelf life study in fruit-based baby foods during post packaging storage
- Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol
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book
-
chapter
- Evaluation of the degree of student satisfaction
- Fluorescence-Based Functional Assays for Ca2+-Permeable ThermoTRP Channels
- Implementation of new teaching innovation tools in the biotechnology degree from the UMH: Evaluation of the degree of impact on academic perfomance
- In Silico Approaches for TRP Channel Modulation
- Toxic Effects of Common Environmental Pollutants in Pancreatic b-Cellsand the Onset of Diabetes Mellitus
- UV Exposure and Skin Protective Effects of Plant Polyphenols.
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congress communication
- In vitro characterization of a TRPV1 soft antagonist.
- In vitro characterization of a TRPV1 soft antagonist.
- In vitro characterization of a TRPV1 soft antagonist.
- Potential role of rainbow trout red blood cells as mediators in the immune response induced by DNA vaccines
- A capsaicin-based TRPV1 soft antagonist as an anti-pruritic drug candidate
- A capsaicin-based TRPV1 soft antagonist as an anti-pruritic drug candidate.
- A new family of chiral heterocyclic compounds that blocks the TRPM8 activation.
- A nudibrnach extract interrupt colon cancer progression via ros-mediated ER eestress
- Antiproliferative effectsof H.sanguineus extracts in breast ans colon cancer cell lines
- BCL-XL, but not complement C3, protect alpha-cells against metabolic stress- or proinflammatory-induced apoptosis
- BCL-XL, but not complement C3, protects alpha-cells against metabolic stress- or proinflammatory-induced apoptosis
- BISPHENOL-A MODULATES ION CHANNEL EXPRESSION AND FUNCTION VIA ESTROGEN RECEPTOR ¿ IN MOUSE PANCREATIC BETA CELLS
- Bisphenol A regulates NaV1.7 ramp currents through activation of estrogen receptor ¿ and PI3K in mouse dorsal root ganglion neurons
- Bisphenol-A modulates ion channel expression and activity in mouse pancreatic beta cell via oestrogen receptor beta (ERbeta)
- Changes in K+/Ca2+ currents, Ca2+ signals and secretion in pancreatic alpha and beta cells from aged mice.
- Ciencia por el mundo
- Combinación de ingredientes a base de polifenoles vegetales con aplicaciones y patologías asociadas a la obesidad
- Contribution of hyperpolarizing ion channels to acute cold hypersensitivity induced by oxaliplatin administration.
- Desarrollo de nanopartículas fluorescentes multicolor basadas en complejos lípido-polímero conjugado
- Desarrollo de nanopartículas fluorescentes multicolor basadas en complejos lípido-polímero conjugado
- Desarrollo de nanoplataformas fluorescentes multicolor basadas en complejos lípido-polimero conjugado
- Descubrimiento de nuevas dianas terapéuticas para el tratamiento de la diabetes tipo 1 y tipo 2 basadas en las estrategias de supervivencia de la célula ¿ pancreática.
- Design of multicolour fluorescent nanoparticles based on lipid-conjugated polymer complexes
- Development of an in vitro pre-clinical nociceptor model for studying paclitaxel-induced neuropathic pain
- Development of an in vitro pre-clinical nociceptor model for studying paclitaxel-induced neuropathic pain"
- Differential effects of chronic exposure to bisphenol A on ion channel activity and expression in mouse pancreatic ß-cells
- Diseño de péptidos con posible capacidad inhibitoria contra Zika y Dengue
- Effect of a combination of polyphenols derived from Hibiscus sabdariffa L and Lippia citriodora L on stage I hypertensive patients: A randomized controlled trial
- Effects of aging on K+ and Ca2+ currents and glucose-regulated Ca2+ signals in mouse
- Effects of aging on alpha- and beta-cell mass and function.
- En la cirrosis hepática, los niveles sistémicos de ácidos grasos de cadena corta se correlacionan inversamente con el nivel de endotoxemia y se asocian de forma negativa con una mayor respuesta inflamatoria, un mayor deterioro de la función hepática y un m mayor HVPG
- Exposure to bisphenol-A induces pancreatic ß-cell apoptosis
- IFIT5 participates in the antiviral mechanisms of rainbow trout red blood cells
- Identificación y caracterización de nuevos moduladores de TRPM8
- Implementación de nuevas herramientas de innovación docente en el Grado de Biotecnología de la UMH: Evaluación del grado de satisfacción del alumnado.
- Implementación de nuevas herramientas de innovación docente en el Grado de Biotecnología de la UMH: Evaluación del impacto en el rendimiento académico
- Improving a Natural Compound: Design of innovative neurocosmeceuticals for sensitive skin
- In hepatic cirrhosis, the systemic levels of short chain fatty acids inversely correlate with the level of endotoxemia, and are negatively associated with an increased inflammatory response, impaired liver function and a higher HVPG
- In hepatic cirrhosis, the systemic levels of short chain fatty acids inversely correlate with the level of endotoxemia, and are negatively associated with an increased inflammatory response, impaired liver function and a higher HVPG
- In vitro characterization of a TRPV1 soft antagonist.
- In vitro characterization of a TRPV1 soft antagonist.
- In vivo role of TRP channels in an experimental model of chronic migraine.
- Inhibition of glucolipotoxicity-induced metabolic stress by metabolites from Hibiscus sabdariffa on hypertrophied 3T3-L1 adipocytes
- Interfering with beta-cells or: how type I interferons are implicated in type 1 diabetes
- Interfering with ß-cells or: how type I interferons are implicated in type 1 diabetes
- La interleucina 6 y el TNFalfa se asocian con el perímetro abdominal y el IMC en la estenosis simple y el Nash, respectivamente
- La microbiota intestinal participa en la activación del inflamasoma durante el desarrollo de daño hepático genotóxico
- Los estrógenos y disruptores endocrinos con actividad estrogénica en la célula ß pancreática y su implicación en la viabilidad celular
- Modulation of TRPV1 channels: from bench to bedside.
- Molecular basis of ion channel modulation: Mapping the conformational states of the outer vestibule of KcsA, a prokaryote potassium channel, using homo-FRET
- Multifunctional fluorescent hybrid nanoparticles for controlled drug delivery
- NANOPARTÍCULAS Y NANOFIBRAS DE POLI [METIL VINIL ÉTER ¿ALT¿ (ANHÍDRIDO MALEICO)] (PMVEMA) Y DERIVADOS PARA DRUG DELIVERY
- NKEF, an antiviral protein involved in the immune response of rainbow trout red blood cells
- Polyphenols from Lippia citriodora as potential agonist of the master energy regulator AMPK with synergistic effects
- Quercetin derivatives from Hibiscus sabdariffa to alleviate glucolipotoxicity-induced metabolic stress
- Rainbow trout shape-shifted red blood cells
- Short term BPS exposure effects on metabolic response in adult male C57BL/6 mice
- Structure-antioxidant activity relationships of isolated compounds from a lemon verbena extract
- Study Chronic Effect of 17- ß -Estradiol Over Trp Channels In Nociceptor Terminals In Microfluidic Chambers.
- Synthesis of nanofibers composed of poly(methyl vinyl ether-alt-maleic acid) and derivatives for topical administration of drugs
- Synthesis of nanofibers composed of poly(methyl vinyl ether-alt-maleic acid) and derivatives for topical administration of drugs
- Transcriptome and proteome analyses of red blood cells from rainbow trout challenged with viral haemorrhagic septicaemia virus
- Transdifferentiation and microfluidic chambers as tools to approach the in-vivo sketch of human nociceptors
- Transdifferentiation and microfluidic chambers as tools to approach thein-vivosketch of human nociceptors.
- poster P043
- xBCL-XL, but not complement C3, protects alpha cells against metabolic stress- or proinflammatory-induced apoptosis
- ¿Cómo he llegado a ser quien soy?
- ¿Ganaremos la guerra contra las superbacterias?
- ß -Lactam TRPM8 Antagonists Prevent Chemotherapy-Induced Cold Allodynia.
-
event
- 7TH SPANISH-ITALIAN-PORTUGUESE-FRENCH (SIPF) INTERNATIONAL WORKSHOP ON STRUCTURE AND FUNCTION OF ION CHANNELS AND TRANSPORTERS (Congress Organization)
- 12TH EBSA 10TH ICBP-IUPAP CONGRESS (Congress Organization)
- VII REUNIÓN DE LA RED ESPAÑOLA DE CANALES IÓNICOS / RECI VII (Congress Organization)
- XI JORNADA DE SAN ALBERTO MAGNO (Congress Organization)
- XV CONGRESO ESTUDIANTES DE FARMACIA (X EDICION INTERNACIONAL) (Congress Organization)
-
hiring
-
invited conference
- Bisphenol-A modulates ion channel expression and function via estrogen receptor ß in mouse pancreatic beta cells
- Contaminantes ambientales y obesidad
- Diabetes y desórdenes metabólicos: viejos problemas, nuevas soluciones
- Disruptores endocrinos y resistencia a la insulina
- EDC disturbance of beta-cells and risk of diabetes
- Endocrine Disrupting Chemicals in the Aetiology of Diabetes
- Endocrine Disrupting Chemicals and Diabetes Mellitus
- Ingeniería de proteínas, diseño racional y selección
- LA AMENAZA SILENCIOSA DE LOS DISRUPTORES ENDOCRINOS: un problema de salud pública
- The role of Endocrine Disrupting Chemicals in the etiology of Diabetes Mellitus
- Unconventional actions of environmental estrogens via estrogen receptors
-
operating licence
-
patent
-
person
- AGULLO CHAZARRA, LUZ MARIA
- AL ABDULLA , RUBA
- ALARCON ALARCON, DAVID
- ALMAGRO RUZ, LUCIA
- ARTERO MORALES, MAITE
- BABILONI CHUST, IGNACIO
- BALLESTA PAYA, JUAN JOSE
- BELLO PEREZ, MELISSA LORETO
- BOIX CASTEJON, MARINA
- BUTRON GARCIA, LAURA
- DIAZ RUIZ, CLAUDIA
- FALCO GRACIA, JUAN ALBERTO
- FERRANDIZ HUERTAS, CLOTILDE
- GIL RIVERA, MINERVA
- GIORGI , SIMONA
- GONZALEZ RODRIGUEZ, SARA
- LOZANO RUIZ, BEATRIZ
- LUCAS MAÑOGIL, EFREN
- MEDINA PERIS, ALICIA
- NOMBELA DIAZ, IVAN
- OSUNA TENORIO, GEMA
- PALACIOS RODRIGUEZ, CRISTINA
- PASCUAL MARTINEZ, ROBERTO
- PEREZ GASCON, VICTORIA
- PEREZ SANCHEZ, ALMUDENA
- PUENTE MARIN, SARA
- RENART PEREZ, MARIA LOURDES
-
person (active)
- ALACID MARTINEZ, YOLANDA INMACULADA
- ALONSO MAGDALENA, PALOMA
- ALVAREZ MARTINEZ, FRANCISCO JAVIER
- BARRAJON CATALAN, ENRIQUE
- BONMATI BOTELLA, BEATRIZ
- CHICO GRAS, VERONICA
- DE ANDRES LOPEZ, JORGE
- ENCINAR HIDALGO, JOSÉ ANTONIO
- ESQUEMBRE TOME, ROCIO
- FERNANDEZ ESCAMILLA, ANA MARIA
- FERNÁNDEZ BALLESTER, GREGORIO JOAQUIN
- FERNÁNDEZ CARVAJAL, ASIA
- FERRER MONTIEL, ANTONIO VICENTE
- FUENTES MARHUENDA, ESTHER TERESA
- GAIBAR GARCIA, LIS
- GARCIA HEREDIA, ANABEL
- GIUDICI BESSEGHINI, ANA MARCELA
- GOMEZ PEREZ, FRANCISCO JAVIER
- GONZALEZ NAVAJAS, JOSE MANUEL
- GONZALEZ ROS, JOSE MANUEL
- HERRANZ LOPEZ, MARIA DOLORES
- LOSADA ECHEBERRIA, MARIA
- MALLAVIA MARIN, RICARDO
- MARROQUI ESCLAPEZ, LAURA
- MARTI BRUÑA, NURIA
- MARTINEZ GODFREY, JESICA
- MARTINEZ TOME, MARIA JOSE
- MATEO MARTÍNEZ, CARMEN REYES
- MEDINA GALI, REGLA MARIA
- MICOL MOLINA, VICENTE
- NADAL NAVAJAS, ANGEL
- NEIRA FALEIRO, JOSE LUIS
- OLIVARES VICENTE, MARIA DOLORES
- ORTEGA-VILLAIZAN ROMO, MARIA DEL MAR
- PEREZ GARCIA-ESTAÑ, LUIS
- PEREZ SERNA, ATENEA ALEXANDRA
- POVEDA LARROSA, JOSE ANTONIO
- QUESADA MOLL, IVAN
- RIPOLL ORTS, CRISTINA
- RUBIO CAMACHO, MARTA
- RUIZ TORRES, VERONICA
- SACEDA SANCHEZ, MIGUEL
- SALVADOR MIRA, MARIA ELIZABHET
- SANCHEZ MARZO, NOELIA
- SAURA LOPEZ, DOMINGO
- SOUSA DOS SANTOS, REINALDO
- TORRES MONTERO, MARIA REMEDIOS
- VALERO ROCHE, MANUEL
- VILLALAIN BOULLON, JOSÉ
- VILLALBA RIQUELME, EVA MARIA
- ZAPATER HERNANDEZ, PEDRO
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research project
- 2004/00003/002
- 2015/00364/001
- 2017/00635/001
- APE/2019/017
- BFU2015-66612-P
- BFU2016-77125-R
- BFU2017-86579-R
- CTM2017-88978-R
- CTQ2015-64445-R
- DQ0094VF
- EQC2018-004372-P
- FS1008VF
- GA 825489
- GA Nº 639249
- GA Nº 825712
- GC0071VF
- GC0072VF
- IDIFEDER/2018/020
- IJCI-2015-24482
- INNTAL11/19/011
- MAT2017-86805-R
- OSMOSIS2018/27
- PGC2018-093505-B-I00
- PIEU2018/18
- PROMETEO/2016/006
- RTC-2017-6507-1
- RTI2018-096724-B-C21
- RTI2018-096957-B-C22
- RTI2018-097189-B-C21
- RTI2018-097991-B-I00
- RTI2018-101969-J-I00
- SAF2015-66275-C2-1-R
- SEJI/2018/023
- UR0023VF
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technological support
-
thesis
- Adaptaciones de la célula ¿ pancreática durante el final de la gestación en el ratón: papel de las hormonas gestacionales.
- DESCUBRIMIENTO Y CARACTERIZACIÓN DE LA ACTIVIDAD ANTIVIRAL INDUCIDA POR LAS MOLÉCULAS TIPO CRP DE PEZ CEBRA (DANIO RERIO)
- ESTUDIO DE LA CAPACIDAD ANTIPROLIFERATIVA EN MODELOS CELULARES DE CÁNCER DE MAMA DE UN EXTRACTO DE HOJA DE OLIVO ENRIQUECIDO EN POLIFENOLES
- EVALUACIÓN DE LOS GENES MGMT, SOCS1 Y SOCS3 COMO MARCADORES MOLECULARES DE QUIMIO Y RADIORRESISTENCIA EN MODELOS CELULARES DE GLIOBLASTOMA HUMANO
- LOS ERITROCITOS NUCLEADOS DE PECES EN LA INMUNIZACIÓN FRENTE A RHABDOVIRUS
- LOS ERITROCITOS NUCLEADOS DE PECES EN LA RESPUESTA INMUNE FRENTE A INFECCIONES VÍRICAS
- Modulación de la masa de la célula alfa pancreática en un modelo murino de diabetes autoinmune experimental
- POLIFENOLES DE PLANTAS COMESTIBLES COMO REPROGRAMADORES METABÓLICOS EN CONDICIONES DE GLUCOLIPOTOXICIDAD
- THE STRESS-MEDIATED ANTIPROLIFERATIVE EFFECTS OF MARINE INVERTEBRATE EXTRACTS IN HUMAN COLON CANCER CELL MODELS
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thrid party project