Publicaciones en VIVO

Mapa de la ciencia

Red de Coinvestigador

BARRAJON CATALAN, ENRIQUE

Person (Active)

Positions

Profesor/a Titular Universidad, Ingeniería 2023 -
PDI INVESTIGADOR, Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2018 -
Profesor/a Contratado/a Doctor/a, Ingeniería 2020 -
MIEMBRO, Compuestos bioactivos naturales 2015 -
Profesor/a Ayudante Doctor/a, Ingeniería 2016 - 2020
PDI INVESTIGADOR, Instituto de Biología Molecular y Celular 2013 - 2018
Profesor/a Asociado/a, Ingeniería 2011 - 2016
FPI-MINISTERIO, Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2001 - 2005
BECARIO/A DE INVESTIGACIÓN (INSTITUTOS), Instituto de Biología Molecular y Celular 2003

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supported publications or other works

selected publications

academic article
- Evaluation of Bioactive Effects of Five Plant Extracts with Different Phenolic Compositions against Different Therapeutic Targets. ANTIOXIDANTS. 1-18. 2024
- The Application of Untargeted Metabolomic Approaches for the Search of Common Bioavailable Metabolites in Human Plasma Samples from Lippia citriodora and Olea europaea Extracts. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 1-15. 2024
- Virological History Predicts Non-sustained Viral Suppression with Long-Acting Cabotegravir and Rilpivirine Therapy, independent of Pharmacokinetic Parameters. CLINICAL INFECTIOUS DISEASES. 20-40. 2024
- Analysis of the Arabidopsis venosa4-0 mutant supports the role of VENOSA4 in dNTP metabolism. PLANT SCIENCE. 1-12. 2023
- Cistus albidus L.¿Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential. PLANTS-BASEL. 1-43. 2023
- Open AccessReview Hallmarks and Biomarkers of Skin Senescence: An Updated Review of Skin Senotherapeutics. ANTIOXIDANTS. 1-26. 2023
- Influence of drying temperature and harvesting season on phenolic content and antioxidant and antiproliferative activities of olive (Olea europaea) leaf extracts. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 1-13. 2022
- New regulation on medical devices made of substances: Opportunities and challenges for pharmacological and toxicological research. FRONTIERS IN DRUG SAFETY AND REGULATION. 1-8. 2022
- A Nudibranch Marine Extract Selectively Chemosensitizes Colorectal Cancer Cells by Inducing ROS-Mediated Endoplasmic Reticulum Stress. FRONTIERS IN PHARMACOLOGY. 1-18. 2021
- Antibacterial plant compounds, extracts and essential oils: An updated review on their effects and putative mechanisms of action. PHYTOMEDICINE. 1-16. 2021
- Editorial: Development of Functional Foods From Marine Sources. FRONTIERS IN NUTRITION. 1-2. 2021
- High global anti-oxidant protection and stimulation of the collagen synthesis of new anti-age product containing an optimized active-mix. JOURNAL OF COSMETIC DERMATOLOGY. 1-10. 2021
- Antioxidants and Skin Protection. ANTIOXIDANTS. 1-4. 2020
- Industrial-Scale Study of the Chemical Composition of Olive Oil Process-Derived Matrices. PROCESSES. 1-14. 2020
- Rosemary Diterpenes and Flavanone Aglycones Provide Improved Genoprotection against UV-Induced DNA Damage in a Human Skin Cell Model. ANTIOXIDANTS. 1-19. 2020
- Sweet Cherry Byproducts Processed by Green Extraction Techniques as a Source of Bioactive Compounds with Antiaging Properties. ANTIOXIDANTS. 1-21. 2020
- Tackling Antibiotic Resistance with Compounds of Natural Origin: A Comprehensive Review. BIOMEDICINES. 1-32. 2020
- The antimicrobial capacity of Cistus salviifolius and Punica granatum plant extracts against clinical pathogens is related to their polyphenolic composition.. SCIENTIFIC REPORTS. 1-14. 2020
- Antioxidant and Photoprotective Activity of Apigenin and its Potassium Salt Derivative in Human Keratinocytes and Absorption in Caco-2 Cell Monolayers. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2148-2161. 2019
- Marine Invertebrate Extracts Induce Colon Cancer Cell Death via ROS-Mediated DNA Oxidative Damage and Mitochondrial Impairment. BIOMOLECULES. 771-808. 2019
- Metabolomic analysis of the effects of a commercial complex biostimulant on pepper crops. FOOD CHEMISTRY. 1-10. 2019
- Natural Compounds as New Cancer Treatments. MEDICINES. 1-3. 2019
- Preclinical evaluation of the antimicrobial-immunomodulatory dual action of xenohormetic molecules against Haemophilus influenzae respiratory infection. BIOMOLECULES. 1-3. 2019
- The Potential Synergistic Modulation of AMPK by Lippia citriodora Compounds as a Target in Metabolic Disorders. NUTRIENTS. 2961-2978. 2019
- Anthocyanic pigments from elicited in vitro grown shoot cultures of Vaccinium corymbosum L., cv. Brigitta Blue, as photosensitizer in natural dye-sensitized solar cells (NDSSC). JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY. 69-76. 2018
- Antimicrobial Capacity of Plant Polyphenols against Gram-positive Bacteria: A Comprehensive Review. CURRENT MEDICINAL CHEMISTRY. 1-2. 2018
- New Mammalian Target of Rapamycin (mTOR) Modulators Derived from Natural Product Databases and Marine Extracts by Using Molecular Docking Techniques. MARINE DRUGS. 385-395. 2018
- Nutraceuticals for Skin Care: A Comprehensive Review of Human Clinical Studies. NUTRIENTS. 403-426. 2018
- Nutraceuticals for skin care: how much science is behind to be considered rigorous enough?. AGRO FOOD INDUSTRY HI-TECH. 25-35. 2018
- Plant-derived polyphenols in human health: biological activity, metabolites and putative molecular targets.. CURRENT DRUG METABOLISM. 1-22. 2018
- Rosemary (Rosmarinus officinalis) extract causes ROS-induced necrotic cell death and inhibits tumor growth in vivo. SCIENTIFIC REPORTS. 1-10. 2018
- The multitarget activity of natural extracts on cancer: synergy and xenohormesis. MEDICINES. 1-3. 2018
- An Updated Review on Marine Anticancer Compounds: The Use of Virtual Screening for the Discovery of Small-Molecule Cancer Drugs. MOLECULES. 1037-1050. 2017
- Evaluation of the intestinal permeability of rosemary (Rosmarinus officinalis L.) extract polyphenols and terpenoids in Caco-2 cell monolayers. PLOS ONE. 17206-17207. 2017
- Kinetic improvement of olive leaves¿ bioactive compounds extraction by using power ultrasound in a wide temperature range. ULTRASONICS SONOCHEMISTRY. 466-473. 2017
- Multi-Targeted Molecular Effects of Hibiscus sabdariffa Polyphenols: An Opportunity for a Global Approach to Obesity. NUTRIENTS. 1-27. 2017
- Phenolic compounds in rosemary as potential source of bioactive compounds against colorectal cancer: In situ absorption and metabolism study. JOURNAL OF FUNCTIONAL FOODS. 202-210. 2017
- Pigments for natural dye-sensitized solar cells from in vitro grown shoot cultures. JOURNAL OF PHOTONICS FOR ENERGY. 25503-25505. 2017
- Polyphenols as Promising Drugs against Main Breast Cancer Signatures. ANTIOXIDANTS. 1-24. 2017
- Shotgun proteomic analysis to study the decrease of xenograft tumor growth after rosemary extract treatment. JOURNAL OF CHROMATOGRAPHY A. 90-100. 2017
- The flavonol-enriched Cistus albidus chloroform extract possesses in vivo anti-inflammatory and anti-nociceptive activity. JOURNAL OF ETHNOPHARMACOLOGY. 210-218. 2017
- Air-borne ultrasonic application in the drying of grape skin: Kinetic and quality considerations. JOURNAL OF FOOD ENGINEERING. 251-258. 2016
- Kinetic improvement of olive leaves' bioactive compounds extraction by using power ultrasound in a wide temperature range. ULTRASONICS SONOCHEMISTRY. 466-473. 2016
- Lemon balm extract (Melissa officinalis, L.) promotes melanogenesis and prevents UVB-induced oxidative stress and DNA damage in a skin cell model. JOURNAL OF DERMATOLOGICAL SCIENCE. 169-177. 2016
- Validation of the AlamarBlue® assay as a fast screening method to determine the antimicrobial activity of botanical extracts. PLOS ONE. 1-3. 2016
- A bioguided identification of the active compounds that contribute to the antiproliferative/cytotoxic effects of rosemary extract on colon cancer cells. FOOD AND CHEMICAL TOXICOLOGY. 215-222. 2015
- Drying and storage of olive leaf extracts. Influence on polyphenols stability. INDUSTRIAL CROPS AND PRODUCTS. 1-3. 2015
- Effect of Instant Controlled Pressure Drop (DIC) pre-treatment on conventional solvent extraction of phenolic compounds from grape stalk powder. INDUSTRIAL CROPS AND PRODUCTS. 1-2. 2015
- Lemon verbena (Lippia citriodora) polyphenols alleviate obesity-related disturbances in hypertrophic adipocytes through AMPK-dependent mechanisms. PHYTOMEDICINE. 605-614. 2015
- Permeability Study of Polyphenols Derived from a Phenolic-Enriched Hibiscus sabdariffa Extract by UHPLC-ESI-UHR-Qq-TOF-MS. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 18396-18411. 2015
- Physicochemical characterization of pomegranate wines fermented with three different Saccharomyces cerevisiae yeast strains. FOOD CHEMISTRY. 848-855. 2015
- The Promiscuous and Synergic Molecular Interaction of Polyphenols in Bactericidal Activity: An Opportunity to Improve the Performance of Antibiotics?. PHYTOTHERAPY RESEARCH. 1-3. 2015
- Volatile profile of Spanish Cistus plants as sources of antimicrobials for industrial applications. INDUSTRIAL CROPS AND PRODUCTS. 1-2. 2015
- Differential metabolomic analysis to study the potential antiproliferative mechanism of olive leaf extract in JIMT-1 breast cancer cell line. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 1-2. 2014
- In vitro duodenal lipolysis of lipid-based drug delivery systems studied by HPLC¿UV and HPLC¿MS. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 396-404. 2014
- Influence of drying on the retention of olive leaf polyphenols infused into dried apple.. FOOD AND BIOPROCESS TECHNOLOGY. 1-9. 2014
- Influence of olive leaf processing on the bioaccessibility of bioactive polyphenols. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 6190-6198. 2014
- Molecular Promiscuity of Plant Polyphenols in the Management of Age-Related Diseases: Far Beyond Their Antioxidant Properties. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 141-159. 2014
- Protective effects of citrus and rosemary extracts on UV-induced damage in skin cell model and human volunteers. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY. 12-18. 2014
- Sucrose supplementation during traditional carob syrup processing affected its chemical characteristics and biological activities. FOOD SCIENCE AND TECHNOLOGY-LEBENSMITTEL-WISSENSCHAFT & TECHNOLOGIE. 1-8. 2014
- Use of novel drying technologies to improve the retention of infused olive leaf polyphenols. DRYING TECHNOLOGY. 1-2. 2014
- Correlation between the antibacterial activity and the composition of extracts derived from various Spanish Cistus species. FOOD AND CHEMICAL TOXICOLOGY. 313-322. 2013
- IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations. SCIENTIFIC REPORTS. 2560-2561. 2013
- Immunoliposome encapsulation increases cytotoxic activity and selectivity of curcumin and resveratrol against HER2 overexpressing human breast cancer cells.. BREAST CANCER RESEARCH AND TREATMENT. 55-65. 2013
- Influence of air temperature on drying kinetics and antioxidant potential of olive pomace.. JOURNAL OF FOOD ENGINEERING. 516-524. 2013
- Kinetic and compositional study of phenolic extraction from olive leaves (var. Serrana) by using power ultrasound. INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES. 120-129. 2013
- Melittin-loaded immunoliposomes against viral surface proteins, a new approach to antiviral therapy. ANTIVIRAL RESEARCH. 218-221. 2013
- Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells. FOOD AND CHEMICAL TOXICOLOGY. 1-3. 2013
- Silibinin suppresses EMT-driven erlotinib resistance by reversing the high miR-21/low miR-200c signature in vivo. SCIENTIFIC REPORTS. 2459-2460. 2013
- Stem cell-like ALDHbright cellular states in EGFR-mutant non-small cell lung cancer: A novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin. CELL CYCLE. 0-1. 2013
- Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: A new family of gerosuppressant agents. CELL CYCLE. 555-574. 2013
- A metabolite-profiling approach to assess the uptake and metabolism of phenolic compounds from olive leaves in SKBR3 cells by HPLC-ESI-QTOF-MS. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 121-126. 2012
- Bioavailability study of a polyphenol-enriched extract from Hibiscus sabdariffa in rats and associated antioxidant status. . MOLECULAR NUTRITION & FOOD RESEARCH. 1590-1595. 2012
- Influence of freezing and dehydration of olive leaves (var. Serrana) on extract composition and antioxidant potential.. FOOD RESEARCH INTERNATIONAL. 189-196. 2012
- SYNERGISM OF PLANT-DERIVED POLYPHENOLS IN ADIPOGENESIS: PERSPECTIVES AND IMPLICATIONS. PHYTOMEDICINE. 253-261. 2012
- USE OF ADVANCED TECHNIQUES FOR THE EXTRACTION OF PHENOLIC COMPOUNDS FROM TUNISIAN OLIVE LEAVES: PHENOLIC COMPOSITION AND CYTOTOXICITY AGAINST HUMAN BREAST CANCER CELLS. FOOD AND CHEMICAL TOXICOLOGY. 1817-1825. 2012
- A systematic study of the polyphenolic composition of aqueous extracts deriving from several Cistus genus species evolutionary relationship. PHYTOCHEMICAL ANALYSIS. 303-312. 2011
- Cell viability effects and antioxidant and antimicrobial activities of tunisian date syrup (Rub El Tamer) polyphenolic extracts.. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 402-406. 2011
- Potential medicinal benefits of high intensity sweetener from Stevia. INTERNATIONAL SUGAR JOURNAL. 1-6. 2011
- High-performance liquid chromatography with diode array detection coupled to electrospray time-of-flight and ion-trap tandem mass spectrometry to identify phenolic compounds from a Cistus ladanifer aqueous extract. PHYTOCHEMICAL ANALYSIS. 0-99. 2009
chapter
- Cancer and Obesity: Crosstalk Between Adipocytes and Cancer Cells in the Tumor Microenvironment as a New Target in Cancer Research. Interdisciplinary cancer research. 1-23. 2024
- Evolución del plan formativo en el marco de un programa para la realización de trabajos de fin de grado interdisciplinares. CALIDAD E INNOVACIÓN PEDAGÓGICA Experiencias docentes y tecnológicas aplicadas al aula. 2305-2315. 2024
- Plant-Derived Natural Productsfor the Treatment of Bacterial Infections. Handbook of experimental pharmacology. 1-29. 2024
- Formación Transversal y Trabajos Fin de Grado Interdisciplinares. Nuevos retos educativos en la enseñanza superior frente al desafío COVID-19. 605-616. 2021
- UV Exposure and Skin Protective Effects of Plant Polyphenols.. A Handbook of Environmental Toxicology: Human Disorders and Ecotoxicology.. 457-474. 2019
- Differential absorption of curcuminoids between free and liposomed curcumin formularions. Curcumin. Clinical uses, health effects and potential complications. 99-111. 2016
- Rockroses (Cistus sp.) Oils. Essential Oils in Food Production, Preservation, Flavour and Safety. 649-658. 2016
- Immunoliposomes: A Multipurpose Strategy in Breast Cancer Targeted Therapy. Breast Cancer - Current and Alternative Therapeutic Modalities. 1-18. 2011
congress communication
patent
- Extracción de compuestos biológicamente activos a partir de residuos de la industria de la vinificación
- METODO DE PRODUCCIÓN DE PECTINA MODIFICADA DE CITRICOS

presentations

invited conference
- LOOKING FOR NEW INGREDIENTS IN NATURE SCREENING AND COSMETIC APPLICATIONS, Conferencia 2023
- Grupo de compuestos bioactivos naturales, Conferencia 2017
- El estrés oxidativo como arma antitumoral, Conferencia 2016