Research Report
-
2016
-
academic article
- AMPK modulatory activity of olive-tree leaves phenolic compounds: Bioassay-guided isolation on adipocyte model and in silico approach
- Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of alpha 7 nicotinic receptors with analgesic activity
- An Updated Review on Marine Anticancer Compounds: The Use of Virtual Screening for the Discovery of Small-Molecule Cancer Drugs
- An introduction to the special issue on biomolecular NMR
- Differential binding of monovalent cations to KcsA: Deciphering the mechanisms of potassium channel selectivity
- Effect of a 2000-m running test on antioxidant and cytokine response in plasma and circulating cells.
- El profesor Francis Mojica gana el Premio Fundación BBVA Fronteras del Conocimiento dotado con 400.000 euros
- El profesor Micol Molina y su ponencia sobre "Bioestimulantes Naturales" abren la IX Semana de la Ciencia de Ars Creatio
- Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution
- Evaluation of the intestinal permeability of rosemary (Rosmarinus officinalis L.) extract polyphenols and terpenoids in Caco-2 cell monolayers
- Fluorescent Biosensor for Phosphate Determination Based on Immobilized Polyfluorene-Liposomal Nanoparticles Coupled with Alkaline Phosphatase
- Gran éxito de la Feria "Un paseo por la Ciencia" de Torrevieja
- Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma
- Identification of diverse defense mechanisms in trout red blood cells in response to VHSV halted viral replication
- Infectious pancreatic necrosis virus triggers antiviral immune response in rainbow trout red blood cells, despite not being infective
- Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B
- Intrinsically disordered inhibitor of glutamine synthetase is a functional protein with random-coil-like pKa values
- Kinetic improvement of olive leaves¿ bioactive compounds extraction by using power ultrasound in a wide temperature range
- La IX Semana de la Ciencia, llega a su ecuador
- La IX Semana de la ciencia aborda el mundo de la robótica con la conferencia "Tecnología y Salud. Cyborgs"
- La IX edición de la Semana de la Ciencia se clausuró con el "broche de oro" de una conferencia de tecnología espacial
- Lipids as central modulators of sensory TRP channels.
- Microbes go nano
- Molecular mechanisms involved in the non-monotonic effect of bisphenol-A on Ca2+ entry in mouse pancreatic ß-cells.
- Multi-Targeted Molecular Effects of Hibiscus sabdariffa Polyphenols: An Opportunity for a Global Approach to Obesity
- Neutralization of viral infectivity by zebrafish c-reactive protein isoforms
- Non-enzymatic browning due to storage is reduced by using clarified lemon juice as acidifier in industrial-scale production of canned peach halves
- Nutraceuticals molecular targets (I) The divorce between legislation, market and science
- Nutraceuticals molecular targets (II) A novel way of approaching health by using nutraceuticals: Combined -omics and virtual screening
- Nutraceuticals molecular targets (III) Targeting protein receptors with polyphenols as new anti-obesity therapies
- Phenolic compounds in rosemary as potential source of bioactive compounds against colorectal cancer: In situ absorption and metabolism study
- Physicochemical characterization of special persimmon fruit beers using Bohemian Pilsner malt as a base
- Pigments for natural dye-sensitized solar cells from in vitro grown shoot cultures
- Poly(methyl vinyl ether-alt-maleic acid) and ethyl monoester as building polymers for drug-loadable electrospun nanofibers
- Polyhydroxyalkanoate-associated phasins as phylogenetically heterogeneous, multipurpose proteins
- Polyphenols as Promising Drugs against Main Breast Cancer Signatures
- Pressurized liquid extraction of Neochloris oleoabundans for the recovery of bioactive carotenoids with anti-proliferative activity against human colon cancer cells.
- Protective immunity against Megalocyticivirus infection in rock bream (Oplegnatus fasciatus) following CpG ODN administration
- Selective exclusion and selective binding both contribute to ion selectivity in KcsA, a model potassium channel
- Shotgun proteomic analysis to study the decrease of xenograft tumor growth after rosemary extract treatment
- Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism
- Sphingosine-1-Phosphate and the S1P3 Receptor Initiate Neuronal Retraction via RhoA/ROCK Associated with CRMP2 Phosphorylation
- Spontaneous membrane insertion of a dengue virus NS2A peptide
- Synthesis, high-throughput screening and pharmacological characterization of ß-lactam derivatives as TRPM8 antagonists
- The PipX Protein, When Not Bound to Its Targets, Has Its Signaling C¿Terminal Helix in a Flexed Conformation
- The flavonol-enriched Cistus albidus chloroform extract possesses in vivo anti-inflammatory and anti-nociceptive activity
- The isolated, twenty-three-residue-long, N-terminal region of the glutamine synthetase inactivating factor binds to its target
- Towards understanding the molecular basis of ion channel modulation by lipids: Mechanistic models and current paradigms
- Trifluoroethanol-induced conformational transition of the C-terminal sterile alpha motif (SAM) of human p73
-
chapter
- Cambios bioquímicos y psicológicos en estudiantes universitarios entrenando ejercicios aeróbicos y consumiendo extractos de Hierba Luisa
- Efectos de los tratamientos con Azotobacter chroococcum sobre la germinación y el desarrollo de plántulas de lechuga y escarola en semillero.
- Efectos de los tratamientos con azotobacter chroococcum sobre la producción de lechugas y escarolas en cultivo ecológico y tradicional
-
congress communication
- ANTIMICROBIAL ACTIVITY OF PEPTIDES DERIVED FROM LYTA AUTOLYSIN AGAINST STREPTOCOCCUS PNEUMONIAE
- Actium(R), an example of how Agrotecnología(R) groups demostrates the real utility and mechanism of actium of its biostimulant products
- Actividad antimicrobiana in vitro de péptidos derivados de la auolisina LytA de Streptococcus pneumoniae
- Addition of choline-binding modules (CBMs) causes aggregation and inhibition of cell separation in Streptococcus pneumoniae growth cultures
- Antimicrobial capacity of plant extracts and pure polyphenolic compounds on intrahospital pathogenic species
- Antimicrobial effect of esters of bicyclic amines on Streptococcus pneumoniae biofilms
- Antioxidant activity and intestinal absorption of apigenin and its potassium salt derivative in Caco-2 cell monolayers
- Antioxidant activity and photoprotection of Mediterranean plants extracts
- Antioxidant activity and photoprotective effect of citrus and olive formulations on UVB-induced damage in human keratinocytes
- Antioxidant enriched olive leaf extracts show antiproliferative activity in cellular models of breast cancer
- Antipneumococcal effect of peptides based on isolated choline-binding repeats. PHA-binding domains of phasins as antipneumococcal polypeptides
- Assessment of viral interference in a birnavirus carrier cell culture against superinfection with VHSV by using co-culture systems
- Capacidad antimicrobiana de estracto vegetales y compuestos polifenólicos puros sobre especies patógenas intrahospitalarios
- Cribado molecular in silico para el descubrimiento de inhibidores de PBP2a
- Development of multifunctional fluorescent hybrid nanoparticles based on conjugated polyelectrolytes
- Development of nanocarriers polyelectrolytes with antibiotics as antimicrobial agents for dual use: drugs and bioimaging probes in human health
- Diseño in silico de nuevos moduladores del canal iónico TRAAK para el tratamiento de dolor crónico
- Effect of persimmon extract in 3T3 L1 cells
- Effects of metabolites derived from Hibiscus sabdariffa on high glucose-induced oxidative stress and inflammation in hypertrophied 3T3-L1 adipo
- Electrospun poly(methyl vinyl ether-alt-maleic anhydride) nanofibers with loading capacity for therapeutic molecules such as 5-aminolevulinic acid
- Externally added choline-binding modules (CBMs) target the pneumococcal cell wall and affect bacterial growth
- Fish red blood cells halted VHSV and IPNV infections together with mounting antiviral responses
- Fluorescent biosensor for alkaline phosphate inhibitors based on immobilized polyfluorene nanoparticles
- Hibiscus and lemon verbena polyphenols: Assessment for weight management in overweight volunteers. Appetite control and satiety Autores Marina Boix-Castejón, Maria Herranz-Lópe
- Impresión en 3D y Docencia en Biología, Bioquímica y Biotecnología. Proyección para las personas con discapacidad visual
- In silico design of new TRAAK ion channel modulators for the treatment of chronic pain
- In silico design of new TRAAK ion channel modulators for the treatment of chronic pain
- In vitro antiviral activity of natural and synthetic compounds against viral diseases of salmonid and cyprinid fish
- Influence of drying temperature and harvesting season on phenolic content and antioxidant activity of olive (Olea europaea) leaf extracts
- La adición externa de módulos de unión a colina afecta al crecimiento de Streptococcus pneumoniae mediante la unión a la pared celular
- La inhibición de PTK6 potencia los efectos del anticuerpo anti EGFR cetuximab y de los inhibidores de la actividad tirosin kinasas del receptor sobre la proliferación de células tumorales pancreáticas.
- Líneas de mejora de tomate Muchamiel y De la pera con resistencia genética a virosis obtenidas en la EPSO-UMH: una alternativa interesante para agricultura ecológica
- Membrane insertion of a Dengue virus NS2A segment. A computational study
- Molecular screening in silico for the discovery of inhibitors of PBP2a
- New insights into the inactivated state of the potassium channel KcsA
- Olive leaf polyphenols alleviate oxidative stress and improve mitochondrial function in high glucose-induced 3T3-L1 hypertrophic adipocytes
- Optimization of neuronal differentiation for the study of MeCP2 protein expression
- Optimization of neuronal differentiation for the study of MeCP2 protein expression
- PHA-binding domains of phasins as antipneumococcal polypeptides
- Phenolic concentration and antioxidant activity of Mediterranean plants extracts
- Plant derived polyphenols alleviate obesity related pathologies in overweight volunteers: potential role of AMPK
- Prevention of UVB-induced Oxidative Stress and DNA damage in human keratinocytes by citrus and olive formulations
- Proteomic study of VHSV infected trout RBCs
- Quercetin derivatives from Hibiscus sabdariffa reduce lipid content and increase mitochondrial biogenesis in hypertrophied 3T3-L1 adipocytes
- RNA¿seq of rainbow trout RBCs transfected with a DNA vaccine in vitro shows a potential role of trout RBCs as mediators in the immune response induced by DNA vaccines in fish.
- Rosemary (Rosmarinus officinalis L) extract increases ROS and modulates Nrf2 pathway in human colon cancer cell lines
- Synthesis and characterization of three light-emitters of copolylfluorenes for biotechnological applications
- The antiproliferative effects of four marine invertebrate ectracts in colon cancer cells in relation to the modulation of oxidative stress-related pathways
- The intracellular metabolites of quercetin derivatives correlate with oxidative stress in hypertrophied 3T3-L1 adipocytes
- The protective antioxidant effect of Lemon balm extract against UVB-induce damage in a skin cell model
- Tryptamine-based derivatives as new TRPM8 modulators: in vitro and in vivo activity.
-
event
-
hiring
-
invited conference
-
operating licence
-
patent
-
person
- AGULLO CHAZARRA, LUZ MARIA
- ALARCON ALARCON, DAVID
- ARTERO MORALES, MAITE
- BELLO PEREZ, MELISSA LORETO
- BUTRON GARCIA, LAURA
- FAJARDO SANCHEZ, EMMANUEL
- GEA BOTELLA, SARA
- GONZALEZ RODRIGUEZ, SARA
- JORQUERA MARTINEZ-ABARCA, RAQUEL- ANA
- LUCAS MAÑOGIL, EFREN
- MAESTRO GARCIA-DONAS, MARIA BEATRIZ
- MANENSCHIJN , JAN-ALBERT
- MARTINEZ-LACACI FORTUNY, MARIA ISABEL
- MOLINA GALLEGO, MARIA LUISA
- NOMBELA DIAZ, IVAN
- PEREZ SANCHEZ, ALMUDENA
- PUENTE MARIN, SARA
- RENART PEREZ, MARIA LOURDES
- ROIG MOLINA, EMMA
- SANZ MORALES, JESUS MIGUEL
-
person (active)
- ALVAREZ MARTINEZ, FRANCISCO JAVIER
- BARRAJON CATALAN, ENRIQUE
- CHICO GRAS, VERONICA
- ENCINAR HIDALGO, JOSÉ ANTONIO
- ESQUEMBRE TOME, ROCIO
- FERNÁNDEZ BALLESTER, GREGORIO JOAQUIN
- FERNÁNDEZ CARVAJAL, ASIA
- FERRER MONTIEL, ANTONIO VICENTE
- GIUDICI BESSEGHINI, ANA MARCELA
- GOMEZ PEREZ, FRANCISCO JAVIER
- GONZALEZ ROS, JOSE MANUEL
- HERRANZ LOPEZ, MARIA DOLORES
- HORNOS ADAN, FELIPE
- LOSADA ECHEBERRIA, MARIA
- MALLAVIA MARIN, RICARDO
- MARROQUI ESCLAPEZ, LAURA
- MARTI BRUÑA, NURIA
- MARTINEZ TOME, MARIA JOSE
- MATEO MARTÍNEZ, CARMEN REYES
- MEDINA GALI, REGLA MARIA
- MICOL MOLINA, VICENTE
- MIRA CARRIO, AMALIA
- NEIRA FALEIRO, JOSE LUIS
- NIKOLAEVA KOLEVA, MAGDALENA
- OLIVARES VICENTE, MARIA DOLORES
- ORTEGA-VILLAIZAN ROMO, MARIA DEL MAR
- PEREZ GARCIA-ESTAÑ, LUIS
- POVEDA LARROSA, JOSE ANTONIO
- RUIZ TORRES, VERONICA
- SACEDA SANCHEZ, MIGUEL
- SAURA LOPEZ, DOMINGO
- TORRES MONTERO, MARIA REMEDIOS
- VALERO ROCHE, MANUEL
- VILLALAIN BOULLON, JOSÉ
-
research project
- 1900/00015/028
- 2005/00019/007
- 2015/00364/001
- 2017/00381/001
- 2017/00424/001
- 50JJ0027VF
- 51FS1003VF
- 51GC0066VF
- 51GI0033VF
- AGL2014-51773-C3-1-R
- AGL2015-67995-C3-1-R
- AORG/2017/101
- BFU2013-43198-P
- BFU2015-66612-P
- BFU2015-70067-REDC
- BIO2013-47684-R
- BIO2016-79323-R
- CTQ2015-64445-R
- GA Nº 639249
- IJCI-2015-24482
- INDICO2017-DIVULGA/038
- INDICO2017-DIVULGA/053
- INDICO2017/CUENTA030
- INDICO2017/CUENTA069
- INDICO2017/ORGANIZA12
- INDICO2017/ORGANIZA13
- INNOVA+2016-DIVULGA/104
- INNOVA+2016-DIVULGA/105
- INNOVA+2016-DIVULGA/106
- INNOVA+2016-DIVULGA/107
- INNOVA+2016-DIVULGA/108
- INNOVA+2016-DIVULGA/109
- INNOVA2016/05
- INNOVA2016/06
- MAT2014-53282-R
- OSMOSIS2016/04
- PIEU-2016/31
- PROMETEO/2016/006
- PROMETEOII/2014/011
- SAF2015-66275-C2-1-R
-
technological support
-
thesis
- ACTIVIDAD ANTITUMORAL DE UN EXTRACTO DE ROMERO (ROSMARINUS OFFICINALIS L.) EN MODELOS IN VITRO E IN VIVO DE CÁNCER DE COLON
- CAMBIOS A NIVEL EPIGENÉTICO Y PROTEÓMICO EN PEZ CEBRA EN RESPUESTA A LA INFECCIÓN CON VIRUS DE LA VIREMIA PRIMAVERAL DE LA CARPA (SVCV)
- CRIBADO FARMACOLÓGICO PARA EL SÍNDROME DE DRAVET
- DISEÑO DE SISTEMAS POLIMÉRICOS NANOESTRUCTURADOS TRANSPORTADORES PARA APLICACIONES BIOMÉDICAS
-
thrid party project