Research Report
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2017
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academic article
- 1¿(2¿,5¿-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1- propanone (RGM079): A Positive Allosteric Modulator of ¿7 Nicotinic Receptors with Analgesic and Neuroprotective Activity
- A Retino-retinal Projection Guided by Unc5c Emerged in Species with Retinal Wave
- A Role for the Host in the Roadmap to Diabetes Stem Cell Therapy
- A refined characterisation of the NeoHepatocyte phenotype necessitates a reappraisal of the transdifferentiation hypothesis.
- Adipose mesenchymal stromal cells isolated from type 2 diabetic patients display reduced fibrinolytic activity
- Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study
- An extra virgin olive oil rich diet intervention ameliorates the nonalcoholic steatohepatitis induced by a high-fat "Western-type" diet in mice
- Angiographic demonstration of Neoangiogenesis after intra-arterial infusion of autologous bone marrow mononuclear cells in diabetic patients with critical limb ischaemia
- Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception
- Bottlenecks in the Efficient Use of Advanced Therapy Medicinal Products Based on Mesenchymal Stromal Cells
- Cost-effective, safe and personalized cell therapy for critical limb ischaemia in type 2 diabetes mellitus
- Cryobanking the genetic diversity in the critically endangered Iberian lynx (Lynx pardinus)from skin biopsies. Investigating the cryopreservation and culture ability of highly valuable explants and cells
- Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder
- Development of a cell-based medicinal product: regulatory structures in the European Union
- Differentiation of Mouse Embryonic Stem Cells Towards Functional Pancreatic Beta-Cell Surrogates through Epigenetic Regulation of Pdx1 by Nitric Oxide
- Directed Pancreatic Acinar Differentiation of Mouse Embryonic Stem Cells via Embryonic Signalling Molecules and Exocrine Transcription Factors
- Dissecting the Brain/Islet Axis in Metabesity
- Dual Trade of Bcl-2 and Bcl-xL in Islet Physiology: Balancing Life and Death With Metabolism Secretion Coupling
- EGF-induced adipose tissue mesothelial cells undergo functional vascular smooth muscle differentiation
- Editorial: Endocrine Disrupters and Metabolism
- Effects of corneal injury on ciliary nerve fibre activity and corneal nociception in mice: A behavioural and electrophysiological study.
- Extra virgin olive oil diet intervention improves insulin resistance and islet performance in diet-induced diabetes in mice
- Functional Vascular Smooth Muscle-like Cells Derived from Adult Mouse Uterine Mesothelial Cells
- GATA4 and GATA6 control mouse pancreas organogenesis
- GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis.
- GATA6 Controls Insulin Biosynthesis and Secretion in Adult ß-Cells
- Gene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg Debate
- Human mesenchymal stem cells prevent neurological complication of radiotherapy
- Impact of exposure to low concentrations of nitric oxide on protein profile in murine and human pancreatic islet cells
- Impact of transient down-regulation of DREAM in human embryonic stem cell pluripotency: The role of DREAM in the maintenance of hESCs
- In utero exposure to bisphenol-A disrupts key elements of retinoid system in male mice offspring
- Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging
- Islet cell development
- L-Type Ca(2+) Channels and SK Channels in Mouse Embryonic Stem Cells and Their Contribution to Cell Proliferation
- LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.
- Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival
- Natural Killer Cells Improve Hematopoietic Stem Cell Engraftment by Increasing Stem Cell Clonogenicity In Vitro and in a Humanized Mouse Model
- Nitric Oxide Prevents Mouse Embryonic Stem Cell Differentiation Through Regulation of Gene Expression, Cell Signaling, and Control of Cell Proliferation
- Nitric oxide repression of Nanog promotes mouse embryonic stem cell differentiation
- Notch and EGFR regulate apoptosis in progenitor cells to ensure gut homeostasis in Drosophila
- Oestrogen receptor ß mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells
- PAX4 Defines an Expandable ß-Cell Subpopulation in the Adult Pancreatic Islet
- PDGF Restores the Defective Phenotype of Adipose-Derived Mesenchymal Stromal Cells from Diabetic Patients
- Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes
- Pancreatic differentiation of Pdx1-GFP reporter mouse induced pluripotent stem cells
- Predictive model to identify the risk of losing protective sensibility of the foot in patients with diabetes mellitus.
- Prenatal activity from thalamic neurons governs the emergence of functional cortical maps in mice
- Regulation of pancreatic ß-cell survival by nitric oxide: Clinical relevance
- Resveratrol Ameliorates the Maturation Process of ß-Cell-Like Cells Obtained from an Optimized Differentiation Protocol of Human Embryonic Stem Cells
- Role of nitric oxide in the maintenance of pluripotency and regulation of the hypoxia response in stem cells
- Single mechanosensitive and Ca2+-sensitive channel currents recorded from mouse and human embryonic stem cells
- Sirtuin 1 regulation of developmental genes during differentiation of stem cells
- Stability of the packaging system and storage conditions of human mesenchymal ítem cell for intraarterial clinical application in patient with critical limb ischaemia
- Standard Requirement of a Microbiological Quality Control Program for the Manufacture of Human Mesenchymal Stem Cells for Clinical Use
- Synaptic mechanisms underlying the intense firing of neocortical layer 5B pyramidal neurons in response to cortico-cortical inputs.
- TRP channels as sensors of Chemically-Induced changes in cell membrane mechanical properties
- The immune boundaries for stem cell based therapies: problems and prospective solutions.
- The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity
- Transcriptional control of mammalian pancreas organogenesis
- Transient Downregulation of Nanog and Oct4 Induced by DETA/NO Exposure in Mouse Embryonic Stem Cells Leads to Mesodermal/Endodermal Lineage Differentiation
- Umbilical cord blood plasma contains soluble NKG2D ligands that mediate loss of natural killer cell function and cytotoxicity
- Update on Activities in Endocrine Disruptor Research and Policy
- Use of Mesothelial Cells and Biological Matrices for Tissue Engineering of Simple Epithelium Surrogates
- Using stem cells to produce insulin
- Zebularine regulates early stages of mESC differentiation: effect on cardiac commitment
- miR-7 Modulates hESC Differentiation into Insulin-Producing Beta-like Cells and Contributes to Cell Maturation.
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chapter
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congress communication
- A RETINO-RETINAL PROJECTION GUIDED BY UNC5C EMERGED IN SPECIES WITH RETINAL WAVES
- A developmental threshold relating retinal and V1 areas predicts the structure of V1 Orientation Preference Maps.
- A retino-retinal projection guided by Unc5c emerged in species with retinal waves
- Asymptomatic versus symptomatic young contact lens wearers: differences in corneal sensitivity, ocular surface temperature, tear stability and blinking rate
- BCL-XL, but not complement C3, protect alpha-cells against metabolic stress- or proinflammatory-induced apoptosis
- BCL-XL, but not complement C3, protects alpha-cells against metabolic stress- or proinflammatory-induced apoptosis
- BISPHENOL-A MODULATES ION CHANNEL EXPRESSION AND FUNCTION VIA ESTROGEN RECEPTOR ¿ IN MOUSE PANCREATIC BETA CELLS
- Basal neuro-immune interactions between resident dentritic cells and corneal sensory nerves
- Bisphenol A regulates NaV1.7 ramp currents through activation of estrogen receptor ¿ and PI3K in mouse dorsal root ganglion neurons
- Bisphenol-A modulates ion channel expression and activity in mouse pancreatic beta cell via oestrogen receptor beta (ERbeta)
- COLD-EVOKED REFLEX BLINK: FROM SENSORY INPUT TO MOTOR OUTPUT
- CORNEAL SENSORY NERVE ACTIVITY CHANGES WITH GROWTH IN THE GUINEA PIG, AFFECTING TEARING AND BLINKING.
- Certificado
- Changes in K+/Ca2+ currents, Ca2+ signals and secretion in pancreatic alpha and beta cells from aged mice.
- Contact lens and eye glass wearers with and witouth ocular symptoms: differences in corneal sensitivity, blinking, tearing and corneal surface temperature.
- Corneal blink reflex amplitude and thermal sensation are proportional to corneal surface temperature changes
- Descubrimiento de nuevas dianas terapéuticas para el tratamiento de la diabetes tipo 1 y tipo 2 basadas en las estrategias de supervivencia de la célula ¿ pancreática.
- Developmental and functional progression of retrosplenial cortex circuits in lisencephalic mouse model
- Differential effects of chronic exposure to bisphenol A on ion channel activity and expression in mouse pancreatic ß-cells
- Effects of aging on K+ and Ca2+ currents and glucose-regulated Ca2+ signals in mouse
- Effects of aging on alpha- and beta-cell mass and function.
- Excitatory/inhibotory balance in pyramidal neurons of layer 2/3 of the mouse granular retrosplenial cortex
- Exposure to bisphenol-A induces pancreatic ß-cell apoptosis
- FISIOLOGÍA HUMANA EN ACCIÓN: EXPERIMENTOS EN EL AULA
- FUNCTIONAL ALTERATIONS FOLLOWING A PHOTOREFRACTIVE KERATECTOMY (PRK) IN AGED MICE CORNEAS
- FUNCTIONAL CHARACTERISTICS OF CORNEAL COLD-SENSITIVE NERVE TERMINALS IN MICE
- IN VIVO WIDE-FIELD IMAGING OF SPONTANEOUS ACTIVITY IN THE DEVELOPING MOUSE NEOCORTEX
- Interfering with beta-cells or: how type I interferons are implicated in type 1 diabetes
- Los estrógenos y disruptores endocrinos con actividad estrogénica en la célula ß pancreática y su implicación en la viabilidad celular
- MECANISMOS NEUROSENSORIALES DE LA SUPERFICIE OCULAR IMPLICADOS EN LA QUERATOCONJUNTIVITIS ALÉRGICA
- MODULATION OF THE TRPA1 ION CHANNEL BY SIGMA 1 RECEPTOR
- Morpho-dynamic changes of corneal cold sensory nerve fibers in the adult living mouse
- Morpho-dynamic changes of corneal cold sensory nerve fibers in the adult living mouse.
- NEURAL ACTIVITY OF CORNEAL SENSORY NERVES IS ALTERED IN THE ABSENCE OF RESIDENT DENDRITIC CELLS
- OCULAR SURFACE TEMPERATURE CHANGES PRODUCED BY TOPICAL PERFLUOROHEXYLOCTANE MODIFIES BLINKING RATE WITHOUT INDUCING CONSCIOUS SENSATIONS.
- Reactivación neuronal en cerebros porcinos tras muerte encefálica.
- SPIDER TOXIN HAINANTOXIN-IV REDUCES THE ENHANCED ACTIVITY OF COLD THERMORECEPTORS IN DRY EYE
- STUDY OF MECP2 DIMERS IN THE DIFFERENTIATION OF HUMAN NEURONS
- Short term BPS exposure effects on metabolic response in adult male C57BL/6 mice
- TRPM8 Antagonist AMTB Impairs the Ability of Cold Thermosensitive Trigeminal Neurons Innervating the Ocular Surface to Encode Cold Stimulus Intensity
- TRPM8-DEPENDENT ACTIVITY OF COLD-SENSITIVE TRIGEMINAL GANGLION NEURONS ENCODES SMALL OCULAR SURFACE TEMPERATURE CHANGES
- TRPM8-DEPENDENT ACTIVITY OF OCULAR COLD THERMORECEPTOR NEURONS CHANGES ALONG THE INTER-BLINK INTERVAL
- The contribution of spontaneous thalamic activity to the emergence of cortical sensory maps
- VISUAL ORIENTATION MAPS IN FERRETS IS RESILIENT TO BRAIN INSULT DURING NEURODEVELOPMENT
- deling of corneal cold sensory nerve fibers in the adult living mouse
- xBCL-XL, but not complement C3, protects alpha cells against metabolic stress- or proinflammatory-induced apoptosis
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event
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external project
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invited conference
- Bisphenol-A modulates ion channel expression and function via estrogen receptor ß in mouse pancreatic beta cells
- Diabetes y desórdenes metabólicos: viejos problemas, nuevas soluciones
- Disruptores endocrinos y resistencia a la insulina
- EDC disturbance of beta-cells and risk of diabetes
- Endocrine Disrupting Chemicals in the Aetiology of Diabetes
- Endocrine Disrupting Chemicals and Diabetes Mellitus
- Improving corneal nerve regeneration: initial results of a novel regenerative agent
- La continua necesidad de innovaciones en la formación de profesionales de la salud
- New Advanced Restorative and Regenerative Therapies to Combat Corneal Blindness
- Ocular neuropathic pain is a consequence of the changes in sensory nerve activity after nerve injury
- Ocular thermography in ocular inflammation and dry eye
- Old and new cation channel blockers to treat ocular discomfort and pain
- Pain and sensation in dry eye disease
- Sensibilidad, dolor y neurotrofismo
- Targeting ion channels to treat corneal neuropathic pain and dry eye
- The role of Endocrine Disrupting Chemicals in the etiology of Diabetes Mellitus
- Unconventional actions of environmental estrogens via estrogen receptors
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operating licence
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person
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person (active)
- ACOSTA BOJ, MARÍA DEL CARMEN
- ALMARAZ GOMEZ, LAURA
- CABEDO MARTI, HUGO
- DE LA PEÑA GARCÍA, ELVIRA MARIA
- GALLAR MARTINEZ, JUANA
- GEIJO BARRIENTOS, EMILIO CARLOS
- IBAÑEZ BALLESTEROS, JOAQUIN
- MARROQUI ESCLAPEZ, LAURA
- MARTINI , FRANCISCO JOSE
- MESEGUER VIGUERAS, VICTOR MANUEL
- NADAL NAVAJAS, ANGEL
- RIPOLL ORTS, CRISTINA
- SALA PLA, SALVADOR
- SORIA ESCOMS, BERNAT
- VALDEOLMILLOS LOPEZ, MIGUEL ANGEL
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research project
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thesis
- ACTIVIDAD DE LOS NERVIOS SENSORIALES DE LA CÓRNEA DURANTE LA DEFICIENCIA LAGRIMAL CRÓNICA Y SU MODULACIÓN FARMACOLÓGICA
- Adaptaciones de la célula ¿ pancreática durante el final de la gestación en el ratón: papel de las hormonas gestacionales.
- EFECTO DE LOS NEUROPÉPTIDOS CODIFICADOS EN LOS GENES TAC1 Y CALCA SOBRE LA CICATRIZACIÓN DE LESIONES EXPERIMENTALES DEL EPITELIO CORNEAL
- MÉTODOS ALTERNATIVOS PARA EL DIAGNÓSTICO DE LA ENFERMEDAD DE OJO SECO: TERMOGRAFÍA CORNEAL Y DETERMINACIÓN DEL FLUJO DE SECRECIÓN LAGRIMAL REFLEJA MEDIANTE ESTIMULACIÓN CORNEAL CON CO2
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thrid party project