ACOSTA BOJ, MARÍA DEL CARMEN

Person (Active)

Positions

Catedrático/a de Universidad, Fisiología 2018 -
PDI INVESTIGADOR, Instituto de Neurociencias 2004 -
MIEMBRO, Neurobiología Ocular 2008 -
Profesor Titular Universidad, Fisiología 2009 - 2018
Profesor/a Titular Universidad, Fisiología 2009 - 2018
Profesor/a Contratado/a Doctor/a, Fisiología 2005 - 2009
Profesor Asociado, Fisiología 2002 - 2005
GRUPO 2: BECAS A TITULADOS DE GRADO MEDIO Y SUPERIOR, Fisiología 1999

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supported publications or other works

selected publications

academic article
- Contribution of TRPM8-mediated activity to thermally-evoked reflex blink. ACTA OPHTHALMOLOGICA. 16043-16043. 2024
- Ocular surface information seen from the somatosensory thalamus and cortex. JOURNAL OF PHYSIOLOGY-LONDON. 1405-1426. 2024
- Cyclosporine A Decreases Dryness-Induced Hyperexcitability of Corneal Cold-Sensitive Nerve Terminals. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 13025-13037. 2023
- Functional Changes of the Ocular Surface Sensory Nerves Due to Contact Lens Use in Young Symptomatic and Asymptomatic Users. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 12-21. 2023
- Maximal tear secretion evoked by controlled stimulation of corneal sensory nerves in healthy individuals and dry eye subjects. OCULAR SURFACE. 80-88. 2023
- The Contribution of TRPA1 to Corneal Thermosensitivity and Blink Regulation in Young and Aged Mice. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 12620-12638. 2023
- An Experimental Model of Neuro-Immune Interactions in the Eye: Corneal Sensory Nerves and Resident Dendritic Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2997. 2022
- Editorial: Sensory abnormalities and primary sensory neurons. FRONTIERS IN CELLULAR NEUROSCIENCE. 1-2. 2022
- Maximal tear secretion evoked by controlled stimulation of corneal sensory nerves in healthy individuals and dry eye subjects.. OCULAR SURFACE. 1-9. 2022
- OSDI Questions on Daily Life Activities Allow to Detect Subclinical Dry Eye in Young Contact Lens Users. JOURNAL OF CLINICAL MEDICINE. 2626. 2022
- Deciphering the action of perfluorohexyloctane eye drops to reduce ocular discomfort and pain.. FRONTIERS IN MEDICINE. 709712-709722. 2021
- Unilateral corneal insult also alters sensory nerve activity in the contralateral eye.. FRONTIERS IN MEDICINE. 767967-767979. 2021
- Sodium Channel Blockers Modulate Abnormal Activity of Regenerating Nociceptive Corneal Nerves After Surgical Lesion. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 31590-31601. 2020
- Topical treatment with a mu opioid receptor agonist alleviates corneal allodynia and corneal nerve sensitization in mice. BIOMEDICINE & PHARMACOTHERAPY. 110794-110808. 2020
- Effects of corneal injury on ciliary nerve fibre activity and corneal nociception in mice: A behavioural and electrophysiological study.. EUR J PAIN-LONDON. 589-602. 2019
- The Effect of Tear Supplementation with 0.15% Preservative-Free Zinc-Hyaluronate on Ocular Surface Sensations in Patients with Dry Eye. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS. 487-492. 2017
- Lacosamide diminishes dryness-induced hyperexcitability of corneal cold sensitive nerve terminals. EUROPEAN JOURNAL OF PHARMACOLOGY. 2-8. 2016
- Abnormal activity of corneal cold thermoreceptors underlies the unpleasant sensations in dry eye disease... PAIN. 399-417. 2016
- Abnormal activity of corneal cold thermoreceptors underlies the unpleasant sensations in dry eye disease. PAIN. 1-12. 2015
- Acid-sensing ion channels detect moderate acidifications to induce ocular pain.. PAIN. 483-495. 2015
- Corneal Sensitivity and Dry Eye Symptoms in Patients with Keratoconus. PLOS ONE. 141621-141632. 2015
- The Effect of Tear Supplementation on Ocular Surface Sensations during the Interblink Interval in Patients with Dry Eye. PLOS ONE. 135629-135641. 2015
- What Causes Eye Pain?. CURRENT OPHTHALMOLOGY REPORTS. 111-121. 2015
- Acid-sensing ion channels detect moderate acidifications to induce ocular pain. PAIN. 1-10. 2014
- Corneal Sensory Nerve Activity in an Experimental Model of UV Keratitis. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 3403-3412. 2014
- Preclinical pharmacology, ocular tolerability and ocular hypotensive efficacy of a novel non-peptide bradykinin mimetic small molecule. EXPERIMENTAL EYE RESEARCH. 170-180. 2014
- Changes in sensory activity of ocular surface sensory nerves during allergic keratoconjunctivitis. PAIN. 1-47. 2013
- Corneal sensitivity in diabetic patients subjected to retinal laser photocoagulation. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 6043-6049. 2011
- Corneal Sensitivity of Diabetic Patients Subjected to Retinal Laser Photocoagulation. OPHTHALMIC RESEARCH. 70-70. 2010
- Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea.. NATURE MEDICINE. 1396-1399. 2010
- Regeneration of functional nerves within full thickness collagen-phosphorylcholine corneal substitute implants in guinea pigs. BIOMATERIALS. 2770-2778. 2010
- Selective changes in human corneal sensation associated with herpes simplex virus keratitis. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 4516-4522. 2010
- Activity of corneal nociceptive nerve fibers during allergic challenge of the ocular surface. ACTA OPHTHALMOLOGICA. 2225-2225. 2009
- Corneal Nerve Activity During Allergic Conjunctivitis. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 6322-6322. 2009
- Corneal Sensitivity and Tear Production Are Decreased in Fibromyalgia Patients. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 4677-4677. 2009
- Decreased corneal sensitivity and tear production in fibromyalgia. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 4129-4134. 2009
- Regeneration of Functional Nerves within Full Thickness Collagen-Phosphorylcholine Corneal Substitute Implants in Guinea Pigs.. BIOMATERIALS. 1-20. 2009
- Sodium Channel Blockers Modulate Abnormal Activity of Regenerating Corneal Sensory Nerves. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 908-908. 2009
- Teaching guidebook of physiology for occupational therapy in the context of the EHEA. EDUCACION MEDICA. 235-235. 2009
- Abnormal Responsiveness of Regeneration Corneal Sensory Fibers Explains Dryness and Pain Sensations after Photorefractive Surgery.. EXPERIMENTAL EYE RESEARCH. 375-375. 2008
- Reproducibility and safety of corneal sensitivity evaluatiion with Belmonte's esthesiometer. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2561-2561. 2008
- The Paradoxical Response to Heat of Corneal Cold Nerve Terminals. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2564-2564. 2008
- Comparative effects of the non-steroidal antiinflammatory drug Nepafenac on corneal sensory nerve fibers responding to chemical irritation. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 182-188. 2007
- Contribution of sensory fibers of the cornea to eye dryness sensations. SOCIETY FOR NEUROSCIENCE ABSTRACTS. 2007
- Effects of Microkeratome Lesion on Corneal Nerves Recorded From the Ciliary Nerves of the Guinea-Pig Eye "in vitro".. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 3471-3471. 2007
- Fisiología Humana para Terapia Ocupacional en el marco del EEES. EDUCACION MEDICA. 167-167. 2007
- Impulse activity in corneal sensory nerve fibers after photorefractive keratectomy. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 4033-4037. 2007
- TRPV1 siRNA Topical Treatment Reduces the Response to Ocular Surface Irritation With Capsaicin.. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 373-373. 2007
- Barium ions inhibit the dynamic response of guinea-pig corneal cold receptors to heating but not to cooling. JOURNAL OF PHYSIOLOGY-LONDON. 573-581. 2006
- Contribution of TRPM8 channels to cold tranduction in primary sensory neurons and peripheral nerve terminals. JOURNAL OF NEUROSCIENCE. 12512-12525. 2006
- Increasing levels of Diadenosine Polyphosphates in Dry Eye. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 4053-4058. 2006
- Influence of age, gender and iris color on mechanical and chemical sensitivity of the cornea and conjunctiva. EXPERIMENTAL EYE RESEARCH. 932-938. 2006
- Activation by heat an capsaicin of peripheral nerve endings and soma of cold primary sensory neurons. JOURNAL OF NEUROSCIENCE. 1-1. 2005
- Características funcionales de las terminaciones sensoriales de la córnea sensibles a cambios de temperatura. REVISTA DE NEUROLOGIA. 100-100. 2005
- Changes in Mechanical, Chemical, and Thermal Sensitivity of the Cornea after Topical Application of Nonsteroidal Anti-inflammatory Drugs. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 282-286. 2005
- Decreased Corneal Sensitivity in Dry Eye Patients. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 4466-4466. 2005
- Decreased Corneal Sensitivity in Patiens with Dry Eye. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2341-2345. 2005
- Influence of age, gender and iris color on corneal sensitivity. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2211-2211. 2005
- Response of colrneal cold nerve terminals to thermal changes. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2210-2210. 2005
- Respuesta paradójica en terminaciones sensoriales de la córnea sensibles al frío. REVISTA DE NEUROLOGIA. 100-100. 2005
- Corneal innervation: sensory and trophic functions. EXPERIMENTAL EYE RESEARCH. 3-3. 2004
- Nerves and sensations from the eye surface. OCULAR SURFACE. 248-253. 2004
- Neural basis of sensation in intact and injured corneas. EXPERIMENTAL EYE RESEARCH. 513-525. 2004
- Recovery of corneal sensitivity of mechanical and chemical stimulation after laser in situ keratomileusis. J REFRACT SURG. 229-235. 2004
- Tear secretion induced by selective stimulation of corneal and conjunctival sensory nerve fibers. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2333-2336. 2004
- Activation of scleral cold thermoreceptors by temperature and blood flow changes. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 697-705. 2003
- Stimulus detection by corneal sensory neurons: from nerve endings to sensations. OPHTHALMIC RESEARCH. 2003
- Trophic interactions between primary sensory neurons and corneal tissues. OPHTHALMIC RESEARCH. 2003
- Neurobiological basis of pain in ophthalmic migraine and therapeutic implications. OPHTHALMIC RESEARCH. 2002
- Corneal morphology and sensitivity in lattice dystrophy type II (familial amyloidosis, Finnish type).. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 634-641. 2001
- Sensations evoked by selective mechanical, chemical and thermal stimulation of the conjunctiva and cornea.. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2063-2067. 2001
- Sensory experiences in humans and single unit activity in cats evoked by polymodal stimulation of the cornea. JOURNAL OF PHYSIOLOGY-LONDON. 511-525. 2001
- Sensory experiences in humans and single unit activity in cats evoked by polymodal stimulation of the cornea.. JOURNAL OF PHYSIOLOGY. 511-525. 2001
- Alteración de la cicatrización corneal y de la respuesta a la capsaicina en ratones knockout para el receptor NK1. REVISTA DE NEUROLOGIA. 2000
- Respuesta de los termoreceptores de frio esclerales a la disminución del flujo sanguíneo ocular. REVISTA DE NEUROLOGIA. 2000
- Changes in the action potential in sensory neurons after peripheral axotomy in vivo. NEUROREPORT. 201-206. 1999
- Measurement of corneal sensitivity to mechanical stimulation with a CO2 esthesiometer.. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 513-519. 1999
- Repetitive application of capsaicin on mice eye: an in vivo model to study analgesia. J. PHYSIOL BIOCHEM. 1999
- Sensations evoked by selective mechanical, chemical and thermal stimulation of the cornea and the conjunctiva. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 1999
- The influence of eye solutions on blinking and ocular comfort at rest and during work at video display terminals. EXPERIMENTAL EYE RESEARCH. 663-669. 1999
- Relación entre modalidad de sensación y actividad nerviosas evocadas por estímulo corneal. REVISTA DE NEUROLOGIA. 1775-1775. 1997
chapter
- Sensory Innervation of the Eye. Adler's Physiology of the Eye, 12th Edition. 383-409. 2024
- Sensory Innervation of the Eye. Adler's Physiology of the Eye. 363-384. 2022
congress communication
patent

presentations

invited conference
- Functional interactions between DCs and sensory nerves in basal corneal conditions, Conferencia 2024
- Unilateral corneal insult also alters sensory nerve activity in the contralateral eye, Conferencia 2022
- Combatir el dolor regenerando los nervios sensoriales., Conferencia 2022
- Ocular thermography in ocular inflammation and dry eye, Conferencia 2019

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ACOSTA BOJ, MARÍA DEL CARMEN

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