SALA PLA, SALVADOR

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Positions

Catedrático/a de Universidad, Fisiología 2018 -
PDI INVESTIGADOR, Instituto de Neurociencias 2004 -
MIEMBRO, Neuroreceptores Asociados a Canales Iónicos 2007 -
Profesor/a Titular Universidad, Fisiología 2007 - 2018
Profesor Titular Universidad, Fisiología 1999 - 2007
Profesor Titular Universidad, FISIOLOGIA 1997 - 1999

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academic article
- Proper Frequency of Perinatal Retinal Waves is Essential for The Precise Wiring of Visual Axons in Non-Image Forming Nuclei. JOURNAL OF NEUROSCIENCE. 1-30. 2024
- The ion channel TRPM8 is a direct target of theimmunosuppressant rapamycin in primary sensory neurons. BRITISH JOURNAL OF PHARMACOLOGY. 3192-3214. 2024
- Natural Polyhydroxy Flavonoids, Curcuminoids, and Synthetic Curcumin Analogs as ¿7 nAChRs Positive Allosteric Modulators. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 973-989. 2021
- 1¿(2¿,5¿-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1- propanone (RGM079): A Positive Allosteric Modulator of ¿7 Nicotinic Receptors with Analgesic and Neuroprotective Activity. ACS CHEMICAL NEUROSCIENCE. 3900-3909. 2019
- A Retino-retinal Projection Guided by Unc5c Emerged in Species with Retinal Wave. CURRENT BIOLOGY. 1149-1160. 2019
- Notch and EGFR regulate apoptosis in progenitor cells to ensure gut homeostasis in Drosophila. EMBO JOURNAL. 1-15. 2019
- Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of ¿7 nicotinic receptors with analgesic activity.. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 157-165. 2018
- Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of alpha 7 nicotinic receptors with analgesic activity. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 1-10. 2017
- Noise Maps for Quantitative and Clinical Severity Towards Long-Term ECG Monitoring. SENSORS. 1-23. 2017
- 1,3-diphenylpropan-1-ones as allosteric modulators of alpha7 nACh receptors with analgesic and antioxidant properties. FUTURE MEDICINAL CHEMISTRY. 731-749. 2016
- N-benzylpiperidine derivatives as alpha7 nicotinic receptor antagonists. ACS CHEMICAL NEUROSCIENCE. 1157-1165. 2016
- Chalcones as positive allosteric modulators of a7 nicotinic acetylcholine receptors: A new target for a privileged structure. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 724-729. 2014
- Effect of Triazine Derivatives on Neuronal Nicotinic Receptors. ACS CHEMICAL NEUROSCIENCE. 683-689. 2014
- Expression and functional properties of ¿7 acetylcholine nicotinic receptors are modified in the presence of other receptor subunits. JOURNAL OF NEUROCHEMISTRY. 1-35. 2012
- A small cytoplasmic region adjacent to the fourth transmembrane segment of the alpha7 nicotinic receptor is essential for its biogenesis. FEBS LETTERS. 2477-2480. 2011
- Mutants of beta-strand beta3 and the loop B in the interface between alpha7 subunits of a homomeric acetylcholine receptor show functional and pharmacological alterations.. JOURNAL OF NEUROCHEMISTRY. 968-978. 2011
- Substitutions of amino acids in the pore domain of homomeric alpha7 nicotinic receptors for analogous residues present in heteromeric receptors modify gating, rectification and binding properties. JOURNAL OF NEUROCHEMISTRY. 40-49. 2011
- Role of loop 9 on the function of neuronal nicotinic receptors.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 654-659. 2010
- Role of the extracellular transmembrane domain interface in gating and pharmacology of a heteromeric neuronal nicotinic receptor. JOURNAL OF NEUROCHEMISTRY. 1036-1045. 2010
- The loop between beta-strands beta2 and beta3 and its interaction with the N-terminal alpha-helix is essential for biogenesis of alpha7 nicotinic receptors. JOURNAL OF NEUROCHEMISTRY. 103-111. 2010
- Binding-gating coupling in a nondesensitizing alpha7 nicotinic receptor. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 410-416. 2009
- Investigating the role of protein folding and assembly in cell-type dependent expression of alpha7 nicotinic receptors using a green fluorescent protein chimera. BRAIN RESEARCH. 7-16. 2009
- Role of the N-terminal alpha-helix in biogenesis of alpha7 nicotinic receptors. JOURNAL OF NEUROCHEMISTRY. 1399-1409. 2009
- Single channel study of the binding-gating coupling in the slowly desensitizing chimeric alpha7-5HT3A receptor. FEBS LETTERS. 1045-1051. 2009
- Interactions between loop 5 and beta-strand beta6¿ are involved in alpha7 nicotinic acetylcholine receptors channel gating. JOURNAL OF NEUROCHEMISTRY. 719-730. 2008
- Molecular characterization and localization of the RIC-3 protein, an effector of nicotinic acetylcholine receptor expression. JOURNAL OF NEUROCHEMISTRY. 617-627. 2008
- Cytoplasmic regions adjacent to the M3 and M4 transmembrane segments influence expression and function of alpha7 nicotinic acetylcholine receptors. A study with single amino acid mutants. JOURNAL OF NEUROCHEMISTRY. 406-415. 2007
- Non-charged amino acids from three different domains contribute to link agonist binding to channel gating in alpha7 nicotinic acetylcholine receptors.. JOURNAL OF NEUROCHEMISTRY. 725-735. 2007
- Improved gating of a chimeric alpha7-5HT3A receptor upon mutations at the M2-M3 extracellular loop. FEBS LETTERS. 256-260. 2006
- The Cysteine-rich with EGF-like domains 2 (CRELD2) protein interacts with the large cytoplasmic domain of human neuronal nicotinic acetylcholine receptor alpha4 and beta2 subunits. JOURNAL OF NEUROCHEMISTRY. 1585-1596. 2005
- Charged Amino Acids of the N-terminal Domain Are Involved in Coupling Binding and Gating in alpha7 Nicotinic Receptors . JOURNAL OF BIOLOGICAL CHEMISTRY. 6642-6647. 2005
- Dual role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors. . JOURNAL OF BIOLOGICAL CHEMISTRY. 27062-27068. 2005
- Mutations of a conserved lysine residue in the N-terminal domain of alpha7 nicotinic receptors affect gating and binding of nicotinic agonists. MOLECULAR PHARMACOLOGY. 1669-1677. 2005
- Potentiation of human alpha4beta2 neuronal nicotinic receptors by a Flustra foliacea metabolite. NEUROSCIENCE LETTERS. 144-149. 2005
- Potentiation of human alpha4beta2 neuronal nicotinic receptors by a Flustra foliacea metabolite. . NEUROSCIENCE LETTERS. 144-149. 2005
- The cysteine-rich with EGF-like domains 2 (CRELD2) protein interacts with the large cytoplasmic domain of human neuronal nicotinic acetylcholine receptor alpha4 and beta2 subunits.. JOURNAL OF NEUROCHEMISTRY. 1585-1596. 2005
- Conservation within the RIC-3 gene family. Effectors of mammalian nicotinic acetylcholine receptor expression. JOURNAL OF BIOLOGICAL CHEMISTRY. 34411-34417. 2003
- Las sustancias elastoviscosas con efectos analgésicos en el dolor de las articulaciones reducen la actividad in vitro de los canales iónicos activados por estiramiento. REVISTA DE LA SOCIEDAD ESPAÑOLA DEL DOLOR. 419-429. 2003
- Effects of benzothiazepines on human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.. BRITISH JOURNAL OF PHARMACOLOGY. 183-192. 2002
- Effects of gingenoside Rg2 on human neuronal nicotinic acetylcholine receptors.. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 1052-1059. 2002
- Effects of ginsenosides, active components of ginseng, on nicotinic acetylcholine receptors expressed in Xenopus oocytes.. EUROPEAN JOURNAL OF PHARMACOLOGY. 37-45. 2002
- Elastoviscous substances with analgesic effects on joint pain reduce stretch-activated ion channel activity "in vitro".. PAIN. 501-508. 2002
- Role of the large cytoplasmic loop of the alpha7 neuronal nicotinic acetylcholine receptor subunit in receptor expression and function.. BIOCHEMISTRY. 7931-7938. 2002
- Modulación de la transducción mecano-nociceptiva por sustancias viscoelásticas.. REV. NEUROL.. 660-660. 2001
- Multiple roles of the conserved residue arginine 209 in neuronal nicotinic receptors.. BIOCHEMISTRY. 8300-8306. 2001
- Papel del residuo conservado arginina 209 en los receptores nicotínicos neuronales.. NEUROLOGY. 2001
- Gating of alpha3beta4 neuronal nicotinic receptor can be controlled by the loop M2-M3 of both beta3 and beta4 subunits.. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 86-92. 1999
- A residue in the middle of the M2-M3 loop of the ß4 subunit specifically affects gating of neuronal nicotinic receptors. FEBS LETTERS. 89-92. 1998
- Neuronal nicotinic acetylcholine receptors on bovine chromaffin cells: cloning, expression, and genomic organization of receptor subunits.. JOURNAL OF NEUROCHEMISTRY. 488-497. 1997
- Role of the putative transmembrane segment M3 in gating of neuronal nicotinic receptors. BIOCHEMISTRY. 2709-2715. 1997
- A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME. 6118-6123. 1996
- Acetylcholine receptor subunit formation requires compatibility between amino acid residues of the M1 and M2 transmembrane segments. FEBS LETTERS. 83-86. 1996
- alpha-Bungarotoxin-sensitive nicotinic receptors on bovine chromaffin cells: molecular cloning, functional expression, and alternative splicing of the a7 subunit. EUROPEAN JOURNAL OF NEUROSCIENCE. 647-665. 1995
chapter
- Effects of elastoviscous solutions of hyluronan derivatives on mechanotransduction. Hyaluronan, Biomedical, Medcal and Clinical Aspects, Vol. 2.. 407-418. 2002
- Response of native stretch-activated ion channels of adult Xenopus Laevis oocytes to hylan solutions.. Hyaluronan Congress Proccedings of the symposium Hyaluron.. 2001
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SALA PLA, SALVADOR

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