Research Report
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2016
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academic article
- AMPK modulatory activity of olive-tree leaves phenolic compounds: Bioassay-guided isolation on adipocyte model and in silico approach
- Alterations in the balance of amyloid precursor protein species in the cerebrospinal fluid of Alzheimer¿s disease patients
- Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of alpha 7 nicotinic receptors with analgesic activity
- An Updated Review on Marine Anticancer Compounds: The Use of Virtual Screening for the Discovery of Small-Molecule Cancer Drugs
- C-terminal fragments of the amyloid precursor protein in cerebrospinal fluid as potential biomarkers for Alzheimer disease
- Differential binding of monovalent cations to KcsA: Deciphering the mechanisms of potassium channel selectivity
- Effect of a 2000-m running test on antioxidant and cytokine response in plasma and circulating cells.
- Evaluation of the intestinal permeability of rosemary (Rosmarinus officinalis L.) extract polyphenols and terpenoids in Caco-2 cell monolayers
- FleQ of Pseudomonas putida KT2440 is a multimeric cyclic diguanylate-binding protein that differentially regulates expression of biofilm matrix components.
- Guidance of retinal axons in mammals
- Identification of diverse defense mechanisms in trout red blood cells in response to VHSV halted viral replication
- Infectious pancreatic necrosis virus triggers antiviral immune response in rainbow trout red blood cells, despite not being infective
- Inhibition of gamma-secretase leads increase level of presenilin-1
- Kinetic improvement of olive leaves¿ bioactive compounds extraction by using power ultrasound in a wide temperature range
- Lipids as central modulators of sensory TRP channels.
- Microbes go nano
- Multi-Targeted Molecular Effects of Hibiscus sabdariffa Polyphenols: An Opportunity for a Global Approach to Obesity
- Neuromuscular junction impairment in Amyotrophic Lateral Sclerosis: reassessing the role of Acetylcholinesterase
- Neutralization of viral infectivity by zebrafish c-reactive protein isoforms
- Nutraceuticals molecular targets (I) The divorce between legislation, market and science
- Nutraceuticals molecular targets (II) A novel way of approaching health by using nutraceuticals: Combined -omics and virtual screening
- Nutraceuticals molecular targets (III) Targeting protein receptors with polyphenols as new anti-obesity therapies
- Phenolic compounds in rosemary as potential source of bioactive compounds against colorectal cancer: In situ absorption and metabolism study
- Pigments for natural dye-sensitized solar cells from in vitro grown shoot cultures
- Polyhydroxyalkanoate-associated phasins as phylogenetically heterogeneous, multipurpose proteins
- Polyphenols as Promising Drugs against Main Breast Cancer Signatures
- Pressurized liquid extraction of Neochloris oleoabundans for the recovery of bioactive carotenoids with anti-proliferative activity against human colon cancer cells.
- Protective immunity against Megalocyticivirus infection in rock bream (Oplegnatus fasciatus) following CpG ODN administration
- Selective exclusion and selective binding both contribute to ion selectivity in KcsA, a model potassium channel
- Shotgun proteomic analysis to study the decrease of xenograft tumor growth after rosemary extract treatment
- Sphingomimetic multiple sclerosis drug FTY720 activates vesicular synaptobrevin and augments neuroendocrine secretion
- Sphingosine-1-Phosphate and the S1P3 Receptor Initiate Neuronal Retraction via RhoA/ROCK Associated with CRMP2 Phosphorylation
- Spontaneous membrane insertion of a dengue virus NS2A peptide
- Synthesis, high-throughput screening and pharmacological characterization of ß-lactam derivatives as TRPM8 antagonists
- The differential organization of F-Actin alters the distribution of organelles in cultured when compared to native chromaffin cells
- The flavonol-enriched Cistus albidus chloroform extract possesses in vivo anti-inflammatory and anti-nociceptive activity
- The role of F-actin in the transport and secretion of chromaffin granules: an historic perspective.
- The ß-amyloid peptide2 compromises Reelin signaling in Alzheimer¿s disease
- Towards understanding the molecular basis of ion channel modulation by lipids: Mechanistic models and current paradigms
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chapter
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congress communication
- ANTIMICROBIAL ACTIVITY OF PEPTIDES DERIVED FROM LYTA AUTOLYSIN AGAINST STREPTOCOCCUS PNEUMONIAE
- Acetylcholinesterase expression levels in Alzheimer¿s. Role of the processing of the proline-rich membrane anchor by ¿-secretase
- Actium(R), an example of how Agrotecnología(R) groups demostrates the real utility and mechanism of actium of its biostimulant products
- Actividad antimicrobiana in vitro de péptidos derivados de la auolisina LytA de Streptococcus pneumoniae
- Addition of choline-binding modules (CBMs) causes aggregation and inhibition of cell separation in Streptococcus pneumoniae growth cultures
- Altered acetylcholinesterase expression in Alzheimer¿s disease. Contribution of the proline-rich membrane anchor processing by gamma-secretase
- Antimicrobial capacity of plant extracts and pure polyphenolic compounds on intrahospital pathogenic species
- Antimicrobial effect of esters of bicyclic amines on Streptococcus pneumoniae biofilms
- Antioxidant activity and intestinal absorption of apigenin and its potassium salt derivative in Caco-2 cell monolayers
- Antioxidant activity and photoprotection of Mediterranean plants extracts
- Antioxidant activity and photoprotective effect of citrus and olive formulations on UVB-induced damage in human keratinocytes
- Antioxidant enriched olive leaf extracts show antiproliferative activity in cellular models of breast cancer
- Antipneumococcal effect of peptides based on isolated choline-binding repeats. PHA-binding domains of phasins as antipneumococcal polypeptides
- Assessment of viral interference in a birnavirus carrier cell culture against superinfection with VHSV by using co-culture systems
- CHARACTERIZATION OF GENETICALLY-LABELED TRPM8-EXPRESSING NEURONS IN THE MOUSE
- Capacidad antimicrobiana de estracto vegetales y compuestos polifenólicos puros sobre especies patógenas intrahospitalarios
- Characterization of Nrg1/ErbB signaling pathway in neurodegeneration mouse models
- Cribado molecular in silico para el descubrimiento de inhibidores de PBP2a
- Diseño in silico de nuevos moduladores del canal iónico TRAAK para el tratamiento de dolor crónico
- Effect of persimmon extract in 3T3 L1 cells
- Effects of metabolites derived from Hibiscus sabdariffa on high glucose-induced oxidative stress and inflammation in hypertrophied 3T3-L1 adipo
- Externally added choline-binding modules (CBMs) target the pneumococcal cell wall and affect bacterial growth
- F-actin functions in the transport and organization of organelles in chromaffin cells
- Fish red blood cells halted VHSV and IPNV infections together with mounting antiviral responses
- Hibiscus and lemon verbena polyphenols: Assessment for weight management in overweight volunteers. Appetite control and satiety Autores Marina Boix-Castejón, Maria Herranz-Lópe
- IDENTIFYING SPONTANOUS ACTIVITY-DEPENDENT MECHANISMS IN VISUAL CIRCUIT FORMATION
- Impresión en 3D y Docencia en Biología, Bioquímica y Biotecnología. Proyección para las personas con discapacidad visual
- In silico design of new TRAAK ion channel modulators for the treatment of chronic pain
- In silico design of new TRAAK ion channel modulators for the treatment of chronic pain
- In vitro antiviral activity of natural and synthetic compounds against viral diseases of salmonid and cyprinid fish
- Influence of drying temperature and harvesting season on phenolic content and antioxidant activity of olive (Olea europaea) leaf extracts
- Ingeniería Biológica aplicada a la detección de antibióticos. Un nuevo biosensor microbiológicos basado en el repressor TtgR de Pseudomonas putida
- La adición externa de módulos de unión a colina afecta al crecimiento de Streptococcus pneumoniae mediante la unión a la pared celular
- La inhibición de PTK6 potencia los efectos del anticuerpo anti EGFR cetuximab y de los inhibidores de la actividad tirosin kinasas del receptor sobre la proliferación de células tumorales pancreáticas.
- Membrane insertion of a Dengue virus NS2A segment. A computational study
- Molecular screening in silico for the discovery of inhibitors of PBP2a
- NRP2 AS A ZIC2 EFFECTOR DURING NEURAL CREST CELLS MIGRATION
- New insights into the inactivated state of the potassium channel KcsA
- Niveles de Reelina en sangre y su relación con diferentes tipos de transtornos del espectro autista
- Olive leaf polyphenols alleviate oxidative stress and improve mitochondrial function in high glucose-induced 3T3-L1 hypertrophic adipocytes
- Optimization of neuronal differentiation for the study of MeCP2 protein expression
- Optimization of neuronal differentiation for the study of MeCP2 protein expression
- PHA-binding domains of phasins as antipneumococcal polypeptides
- Phenolic concentration and antioxidant activity of Mediterranean plants extracts
- Plant derived polyphenols alleviate obesity related pathologies in overweight volunteers: potential role of AMPK
- Potential of the amyloid-ß precursor protein as a cerebrospinal fluid biomarker of Alzheimer¿s disease patients
- Prevention of UVB-induced Oxidative Stress and DNA damage in human keratinocytes by citrus and olive formulations
- Quercetin derivatives from Hibiscus sabdariffa reduce lipid content and increase mitochondrial biogenesis in hypertrophied 3T3-L1 adipocytes
- Rebound increase in presenilin-1 protein levels in response to ¿-secretase inhibition
- Reelin blood levels as a marker of some types of autistic spectrum disorders (ASD)
- Rosemary (Rosmarinus officinalis L) extract increases ROS and modulates Nrf2 pathway in human colon cancer cell lines
- Soluble complexes of Presenilin-1 in Alzheimer¿s cerebrospinal fluid as an asymptomatic biomarker
- The alteration of ApoER2 processing by Aß could modulate Reelin expression
- The antiproliferative effects of four marine invertebrate ectracts in colon cancer cells in relation to the modulation of oxidative stress-related pathways
- The intracellular metabolites of quercetin derivatives correlate with oxidative stress in hypertrophied 3T3-L1 adipocytes
- The protective antioxidant effect of Lemon balm extract against UVB-induce damage in a skin cell model
- Tryptamine-based derivatives as new TRPM8 modulators: in vitro and in vivo activity.
- ZIC2 MODULATES ß-CATENIN LEVELS TO PROMOTE AXON MIDLINE REPULSION
- Zic2 induces axon steering at the midline by increasing the levels of ß-catenin independently of the canonical Wnt signaling
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event
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hiring
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invited conference
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operating licence
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patent
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person
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person (active)
- CRIADO HERRERO, MANUEL
- CUCHILLO IBAÑEZ, INMACULADA
- DEVESA GINER, ISABEL
- ENCINAR HIDALGO, JOSÉ ANTONIO
- FERNANDEZ ESCAMILLA, ANA MARIA
- FERNÁNDEZ BALLESTER, GREGORIO JOAQUIN
- FERNÁNDEZ CARVAJAL, ASIA
- FERRER MONTIEL, ANTONIO VICENTE
- GARCIA MORALES, MARIA DEL PILAR
- GONZALEZ ROS, JOSE MANUEL
- GUTIERREZ PEREZ, LUIS MIGUEL
- HERRANZ LOPEZ, MARIA DOLORES
- MICOL MOLINA, VICENTE
- MORENILLA PALAO, MARIA CRUZ
- PEREZ GARCIA-ESTAÑ, LUIS
- REIG MACIA, JUAN ANTONIO
- SACEDA SANCHEZ, MIGUEL
- SAEZ VALERO, JAVIER
- VILLALAIN BOULLON, JOSÉ
- VILLANUEVA ROIG, JOSE HELIODORO
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research project
- 1900/00015/028
- 2014/00155/001
- 2015/00099/001
- 2017/00381/001
- AGL2014-51773-C3-1-R
- AGL2015-67995-C3-1-R
- AORG/2017/101
- APE/2017/057
- BFU2013-43198-P
- BFU2015-63684-P
- BFU2015-66612-P
- BFU2015-70067-REDC
- BIO2013-47684-R
- BIO2016-79323-R
- INDICO2017-DIVULGA/053
- INDICO2017/CUENTA024
- INDICO2017/CUENTA030
- INDICO2017/CUENTA069
- INDICO2017/ORGANIZA02
- INDICO2017/ORGANIZA12
- INDICO2017/ORGANIZA13
- INNOVA+2016-DIVULGA/104
- INNOVA+2016-DIVULGA/105
- INNOVA+2016-DIVULGA/107
- INNOVA+2016-DIVULGA/108
- INNOVA+2016-DIVULGA/109
- INNOVA+2016-PLE_029
- INNOVA2016/05
- INNOVA2016/06
- OSMOSIS2016/04
- PI15/00665
- PROMETEO/2016/006
- PROMETEOII/2014/011
- SAF2015-66275-C2-1-R
- UMHE15-EE-3244
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technological support
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thesis
- ACTIVIDAD ANTITUMORAL DE UN EXTRACTO DE ROMERO (ROSMARINUS OFFICINALIS L.) EN MODELOS IN VITRO E IN VIVO DE CÁNCER DE COLON
- CAMBIOS A NIVEL EPIGENÉTICO Y PROTEÓMICO EN PEZ CEBRA EN RESPUESTA A LA INFECCIÓN CON VIRUS DE LA VIREMIA PRIMAVERAL DE LA CARPA (SVCV)
- CRIBADO FARMACOLÓGICO PARA EL SÍNDROME DE DRAVET
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thrid party project