selected publications
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academic article
- Multiple sclerosis drug FTY-720 toxicity is mediated by the heterotypic fusion of organelles in neuroendocrine cells. SCIENTIFIC REPORTS. 18471. 2019
- Emerging evidence for the modulatio of exocytosis by signalling lipids. FEBS LETTERS. 1-11. 2018
- Modeling the influence of co-localized intracellular calcium stores on the secretory response of bovine chromaffin cells. COMPUTERS IN BIOLOGY AND MEDICINE. 165-175. 2018
- Multiple Mechanisms Driving F.actin-dependent Transport of Organelles to and from Secretory sites in Bovine Chromaffin Cells. FRONTIERS IN CELLULAR NEUROSCIENCE. 1-12. 2018
- Sphingomimetic multiple sclerosis drug FTY720 activates vesicular synaptobrevin and augments neuroendocrine secretion. SCIENTIFIC REPORTS. 5958. 2017
- The differential organization of F-Actin alters the distribution of organelles in cultured when compared to native chromaffin cells. FRONTIERS IN CELLULAR NEUROSCIENCE. 135. 2017
- The role of F-actin in the transport and secretion of chromaffin granules: an historic perspective.. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 1-6. 2017
- Captivating New Roles of F-Actin Cortex in Exocytosis and Bulk Endocytosis in Neurosecretory Cells. TRENDS IN NEUROSCIENCES. 605-623. 2016
- F-actin cytoskeleton and the fate of organelles in chromaffin cells.. JOURNAL OF NEUROCHEMISTRY. 860-866. 2016
- Sphingomyelin derivatives increase the frquency of microvesicle and granule fusion in chromaffin cells. NEUROSCIENCE. 117-125. 2015
- A THEORETICAL STUDY OF FACTORS INFLUENCING. MATHEMATICAL BIOSCIENCES AND ENGINEERING. 1027-1043. 2014
- Role of Protease-Activated Receptor 2 in Lung Injury Development During Acute Pancreatitis in Rats. PANCREAS. 895-902. 2014
- The distribution of mitochondria and endoplasmic reticulum in. JOURNAL OF CELL SCIENCE. 2014
- Cortical F-actin affects the localization and dynamics of SNAP-25 membrane clusters in chromaffin cells. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 583-592. 2013
- Distribucion mitocondrial en celulas cromafines y su relacion con la secrecion. REVISTA DE NEUROLOGIA. 174-176. 2013
- FTY-720 un analogo de la esfingosina que potencia la liberacion cuantal de catecolaminas. REVISTA DE NEUROLOGIA. 174-176. 2013
- Lipid Metabolites Enhance Secretion Acting on SNARE Microdomains and Altering the Extent and Kinetics of Single Release Events in Bovine Adrenal Chromaffin Cells. PLOS ONE. 75845-75857. 2013
- Neurite extensions in chromaffin cells: study of the influence of the cytoskeletal structure on calcium dynamics and secretion. FRONTIERS IN LIFE SCIENCE. 61-69. 2013
- F-Actin-Myosin II Inhibitors Affect Chromaffin Granule Plasma Membrane Distance and Fusion Kinetics by Retraction of the Cytoskeletal Cortex.. JOURNAL OF MOLECULAR NEUROSCIENCE. 328-338. 2012
- New insights into the role of the cortical cytoskeleton in exocytosis from neuroendocrine cells.. INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY. 109-137. 2012
- The f-actin cortex in chromaffin granule dynamics and fusion: a minireview.. JOURNAL OF MOLECULAR NEUROSCIENCE. 1559-1166. 2012
- Calcium entry through slow-inactivating L-type calcium channels preferentially triggers endocytosis rather than exocytosis, in bovine chromaffin cells. . AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 86-98. 2011
- Modelling F-actin cortex influence on the secretory properties of neuroendocrine cells. COMMUNICATIVE & INTEGRATIVE BIOLOGY. 1-3. 2011
- P2X7 Receptors Trigger ATP Exocytosis and Modify Secretory Vesicle Dynamics in Neuroblastoma Cells.. JOURNAL OF BIOLOGICAL CHEMISTRY. 11370-11381. 2011
- The F-actin cortical network is a major factor influencing the organization of the secretory machinery in chromaffin cells. JOURNAL OF CELL SCIENCE. 727-734. 2011
- Alpha-synuclein sequesters arachidonic acid to modulate SNARE-mediated exocytosis. EMBO REPORTS. 528-533. 2010
- Association of SNAREs and Calcium Channels with the Borders of Cytoskeletal Cages Organizes the Secretory Machinery in Chromaffin Cells. CELLULAR AND MOLECULAR NEUROBIOLOGY. 1-5. 2010
- Pancreatic and pulmonary mast cells activation during experimental acute pancreatitis.. WORLD JOURNAL OF GASTROENTEROLOGY. 3411-3417. 2010
- The organization of the secretory machinery in chromaffin cells as a major factor in modeling exocytosis. HFSP JOURNAL. 85-92. 2010
- t-SNARE cluster organization and dynamics in chromaffin cells. JOURNAL OF NEUROCHEMISTRY. 1550-1556. 2010
- Simulation of Cytoskeleton Influence on spatial Ca2+ dynamics in neuroendocrine cells. BMC NEUROSCIENCE. 31-32. 2009
- Sphingosine facilitates SNARE complex assembly and activates synaptic vesicle exocytosis. NEURON. 683-694. 2009
- Vesicle Motion and Fusion are Altered in Chromaffin Cells with Increased SNARE Cluster Dynamics. TRAFFIC. 172-185. 2009
- A low nicotine concentration augments vesicle motion and exocytosis triggered by K(+) depolarisation of chromaffin cells. EUROPEAN JOURNAL OF PHARMACOLOGY. 81-86. 2008
- Cytoskeletal control of vesicle transport and exocytosis in chromaffin cells. ACTA PHYSIOLOGICA. 165-172. 2008
- Myosin II contributes to fusion pore expansion during exocytosis. JOURNAL OF BIOLOGICAL CHEMISTRY. 10949-10957. 2008
- Cytoskeletal control of vesicle transport and exocytosis in chromaffin cells.. ACTA PHYSIOLOGICA SCANDINAVICA. 165-169. 2007
- GSK3 activation is essential for the snake PLA2 Neurotoxin induced secretion in chromaffin cells.. EUROPEAN JOURNAL OF NEUROSCIENCE. 2341-2348. 2007
- Vesicle movements are governed by the size and dynamics of F-actin cytoskeletal structures in bovine chromaffin cells.. NEUROSCIENCE. 659-669. 2007
- Role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors. JOURNAL OF MOLECULAR NEUROSCIENCE. 153-156. 2006
- Tight coupling of the t-SNARE and calcium channel microdomains in adrenomedullary slices and not in cultured chromaffin cells.. CELL CALCIUM. 1-8. 2006
- The Cysteine-rich with EGF-like domains 2 (CRELD2) protein interacts with the large cytoplasmic domain of human neuronal nicotinic acetylcholine receptor alpha4 and beta2 subunits. JOURNAL OF NEUROCHEMISTRY. 1585-1596. 2005
- Chromaffin Cell F-actin cytoskeleton real-time dynamics during secretion studied by Transmitted Light and Fluorescence Microscopy.. JOURNAL OF CELL SCIENCE. 2871-2880. 2005
- Dual role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors. . JOURNAL OF BIOLOGICAL CHEMISTRY. 27062-27068. 2005
- The cysteine-rich with EGF-like domains 2 (CRELD2) protein interacts with the large cytoplasmic domain of human neuronal nicotinic acetylcholine receptor alpha4 and beta2 subunits.. JOURNAL OF NEUROCHEMISTRY. 1585-1596. 2005
- New roles of myosin II during the vesicle transport and fusion in chromaffin cells. JOURNAL OF BIOLOGICAL CHEMISTRY. 27450-27457. 2004
- Small peptides patterned after the n-terminus domain of snap25 Inhibit snare complex assembly and regulated exocytosis. JOURNAL OF NEUROCHEMISTRY. 124-135. 2004
- Identification of SNARE complex modulators that inhibit exocytosis from an a-helix-constrained combinatorial library. BIOCHEMICAL JOURNAL. 159-166. 2003
- Ñeco, P., Giner, D., Francés, M.M., Viniegra, S., and Gutiérrez, L.M. (2003). Differential participation of Actin and Tubulin-based Vesicle Transport Systems during Secretion in Bovine Chromaffin Cells.. EUROPEAN JOURNAL OF NEUROSCIENCE. 733-742. 2003
- Ñeco, P., Rosetto, O, Gil, A., Montecucco, C., and Gutiérrez, L.M. (2003). Taipoxin induces F-actin fragmentation and enhances release of catecholamines in bovine chromaffin cells . JOURNAL OF NEUROCHEMISTRY. 329-337. 2003
- Modifications in the C terminus of the synaptosome-associated protein of 25 kDa Snap-25) and in the complementary region of synaptobrevin affect the final steps of exocytosis.. JOURNAL OF BIOLOGICAL CHEMISTRY. 9904-9904. 2002
- Modifications in the C terminus of the synaptosome-associated protein of 25 kDa Snap-25) and in the complementary region of synaptobrevin inhibit secretion through the alteration of membrane fusion kinetics.. JOURNAL OF BIOLOGICAL CHEMISTRY. 9904-9909. 2002
- The role of myosin in vesicle transport during bovine chromaffin cell secretion.. JOURNAL OF BIOCHEMISTRY. 405-413. 2002
- Co-localization of vesicles and P/Q Ca2+-Channels explains the preferential distribution of exocytotic active zones in neurites emitted by bovine chromaffin cells.. EUROPEAN JOURNAL OF CELL BIOLOGY. 358-365. 2001
- The temperature and PMA affect different phases of exocytosis in bovine chromaffin cells.. EUROPEAN JOURNAL NEUROSCIENCE. 1380-1386. 2001
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book
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chapter
- Studies of the Secretory Machinery Dynamics by Total Internal Reflection Fluorescence Microscopy in Bovine Adrenal Chromaffin Cells. SNARE Methods and Protocols. 379-389. 2018
- Understanding the role of mitochondria distribution in calcium dynamics and secretion in bovine chromaffin cells. Modeling Cellular Systems. 1-11. 2016
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congress communication
- El cerebro humano: El universo hecho consciencia 2019
- F-actin functions in the transport and organization of organelles in chromaffin cells 2017
- Understanding the Role of Mitochondria Distribution in Calcium-Induced Exocytosis in Bovine Chromaffin Cells 2016
- F-actin organization and the fate of vesicles and organelles 2015
- The nature of chromaffin cell cytoskeleton and art 2015
- F-actin-myosin II, a complex network with multiple functions 2013
- Sphingosine and sphingosine-imetic drugs facilitate SNARE complex assembly and modulate secretory vesicle exocytosis 2013
- Cortical cytoskeleton and granule motion in cultured chromaffin cells 2011
- The F-Actin-Myosin Cytoskeleton Influences the Dynamics of SNAP-25 Microdomains 2011
- Proteínas del complejo de fusión vesicular y su participación en la regulación de la exocitosis 2009
- CITOESQUELETO Y ORGANIZACIÓN DE LA MAQUINARIA SECRETORA EN 2008
- PAPEL DEL CALCIO EXTRA E INTRACELULAR EN LA ENDOCITOSIS EN LA 2008
- A model to understand the role of different myosins in secretion 2007
- ESTUDIO DE LA FUNCION DEL CITOESQUELETO CORTICAL POR COMBINACION DE LAS TECNICAS DE TIRFM Y MICROSCOPIA DE LUZ TRANSMITIDA EN CELULAS CROMAFINES 2007
- SNARE cluster dynamics influences chromaffin granule motion and the probability of fusion. 195-195. 2007
- Transmission Light for studying F-actin dynamics and function 2007
- CAMBIOS DEPENDIENTES DE SNAP-25 EN LA MOVILIDAD DE LAS VESICULAS CROMAFÍN Y SU PROBABILIDAD DE FUSIÓN 2006
- Estudio del co-represor transcripcional MITR en el neuroblastoma SH-SY5Y 2006
- LA MIOSINA II AFECTA A LA CINÉTICA DE FUSION DE GRÁNULOS CROMAFINES INDEPENDIENTEMENTE DE SU INTERACCIÖN CON F-ACTINA 2006
- Myosin II actively expads the exocytotic fusion pore and increases the efficiency of transmitter release 2006
- Myosin II, a versatile protein controlling cytoskeleton dynamics associated with vesicle transport and exocytosis 2006
- DIMEROS DE T-SNARES LOCALIZAN LA RESPUESTA SECRETORA EN CELULAS CROMAFINES EN CULTIVO Y EN RODAJAS DE MEDULA ADRENAL 2005
- LA MAGNITUD DE LOS CAMBIOS CITOESQUELETALES DURANTE LA SECRECION EN CELULAS CROMAFINES 2005
- The role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors 2005
- COMPLEJOS DE SINTAXINA 1/SNAP-25 LOCALIZAN LA RESPUESTA SECRETORA DE CELULAS CROMAFINES EN CULTIVO. 2004
- Chromaffin Cell F-actin cytoskeleton dynamics studied by transmitted light scanning microscopy 2004
- LAS NEUROTOXINAS PLA-2 AUMENTAN LA LIBERACION RAPIDA DE VESICULAS POR FRAGMENTACION DE LA BARRERA CORTICAL DE ACTINA EN CELULAS CROMAFINES 2004
- PLA2 toxins affect cortical F-actin and enhance secretion in Chromaffin Cells. 2004
- REGULACIÓN DE LA EXPANSION DEL PORO DE FUSION EXOCITOTICO POR LA MIOSINA II 2004
- Actin and tubuin-based vesicle transport systems cooperate during secretion in chromaffin cells 2003
- Aislamiento de tres nuevas proteínas que se asocian específicamente con el lazo citoplásmico de la subunidad alfa4 del receptor nicotínico neuronal 2003
- Efecto de la proteína Ric-3 sobre la expresión de los receptores nicotínicos neuronales. 2003
- Estudio de los cambios citoesqueletales con microscopia de luz transmitida. 2003
- Participación de la Miosina II en el transporte vesicular y en la fusion de la celula cromafín 2003
- The Ric-3 protein: an effector of nicotinic acetylcholine receptor expression 2003
- Trap: una nueva proteína que interacciona con el lazo citoplásmico de la subunidad alfa4 del receptor nicotínico neuronal 2003
- Actin and Tubulin-based Vesicle Transport Systems co-operate during secretion in Chromaffin cells. 2002
- Alterations in SNAP-25 and synaptobrevin inhibit secretion by slowing membrane fusion kinetics in chromaffin cells. 2002
- Cytokeletal mechanisms of vesicle transport in neurosecretory chromaffin cells. 2002
- SNAP-25 and synaptobrevin participate in the membrane fusion steps of secretion in chromaffin cells. 2002
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patent
- PEPTIDOS INHIBIDORES DE LA EXOCITOSIS NEURONAL, COMPOSICIONES COSMETICAS Y FARMACEUTICAS QUE LOS COMPONEN
- PEPTIDOS INHIBIDORES DE LA EXOCITOSIS NEURONAL, COMPOSICIONES COSMETICAS Y FARMACEUTICAS QUE LOS COMPONEN
- PEPTIDOS INHIBIDORES DE LA EXOCITOSIS NEURONAL, COMPOSICIONES COSMETICAS Y FARMACEUTICAS QUE LOS CONTIENEN
- Peptidos inhibidores de la exocitosis neuronal, composiciones cosméticas y farmacéuticas que los contienen
- Péptidos inhibidores de la exocitosis neuronal, composisiones cosméticas y farmacéuticas que los contienen.