Research Report
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academic article
- Fasciclin 2 engages EGFR in an auto-stimulatory loop to promote imaginal disc cell proliferation in Drosophila.
- A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair.
- Abnormalities in Cortical GABAergic Interneurons of the Primary Motor Cortex Caused by Lis1 (Pafah1b1) Mutation Produce a Non-drastic Functional Phenotype
- An Experimental Model of Neuro-Immune Interactions in the Eye: Corneal Sensory Nerves and Resident Dendritic Cells
- Cross-Modal Plasticity in Brains Deprived of Visual Input Before Vision.
- Editorial Eye pain: Etiology and therapeutics approaches
- Editorial: Sensory abnormalities and primary sensory neurons
- Emerging Role of HDACs in Regeneration and Ageing in the Peripheral Nervous System: Repair Schwann Cells as Pivotal Targets
- Epithelial and sensory mechanisms of nasal hyperreactivity
- G protein-coupled estrogen receptor activation by bisphenol-A disrupts the protection from apoptosis conferred by the estrogen receptors ER¿ and ERß in pancreatic beta cells
- In Vitro Assays to Identify Metabolism-Disrupting Chemicals with Diabetogenic Activity in a Human Pancreatic ß-Cell Model
- Maximal tear secretion evoked by controlled stimulation of corneal sensory nerves in healthy individuals and dry eye subjects.
- Membrane potential instabilities in sensory neurons: mechanisms and pathophysiological relevance
- OSDI Questions on Daily Life Activities Allow to Detect Subclinical Dry Eye in Young Contact Lens Users
- Properties of the epileptiform activity in the cingulare cortex of a mouse model of LIS1 dysfunction
- Small fiber neuropathy in the cornea of Covid-19 patients associated with the generation of ocular surface disease
- Spontaneous Thalamic Activity Modulates the Cortical Innervation of the Primary Visual Nucleus of the Thalamus.
- Stress estimation by the prefrontal cortex asymmetry: Study on fNIRS signals
- TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy
- The pancreatic beta-cell in ageing: Implications in age-related diabetes
- Thoracoscopic segmentectomy versus lobectomy: A propensity score¿matched analysis
- Validation of Six Commercial Antibodies for the Detection of Heterologous and Endogenous TRPM8 Ion Channel Expression
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chapter
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congress communication
- 17ß-estradiol and the endocrine disruptor Bisphenol-A promote different ion channel regulation in the human beta cell line EndoC-ßH1.
- Aging and alterations in pancreatic alpha and beta-cells: implication in age-related diabetes.
- Alterations in the anterior cingulate area and dentate gyrus in lis1 mutant mouse underlies a schizophrenia-like phenotype
- Assessment of pancreatic ß-cell function as a tool to identify diabetogenic chemicals
- Avances en el tratamiento y prevención de la neuropatía asociada a quimioterapéuticos CIPN por derivados del platino.
- Contribution of TTX-resistant Nav channels to the generation of membrane potential instabilities in mouse trigeminal neurons
- Divergent patterns of spontaneous activity in distinct sensory cortices during early development
- Efecto del IFN¿ en la función de las células ¿ y ß pancreáticas
- Effects of Lis1 gene loss in parvalbumin expressing cells on the mouse cerebellar cortex
- Effects of contact lens wearing on corneal sensitivity and reflex functions
- Evaluación de inhibidores de la vía de interferón como nuevas terapias para la diabetes tipo 1
- Flash Talk
- Flash Talk
- G protein-coupled estrogen receptor activation by Bisphenol-A disrupts protection from apoptosis conferred by estrogen receptors ER¿ and ERß in pancreatic beta cells
- GRUPO EXPERIMENTACIÓN BÁSICA EN DIABETES DE LA SED: Vimentin as a regulator of cell survival and endoplasmic reticulum stress in pancreatic ¿- and ß-cells
- Human bone marrow derived mesenchymal stem cells as a therapeutical approach for X-linked adrenoleukodystrophy
- IDENTIFICACIÓN DE NUEVAS DIANAS TERAPÉUTICAS PARA EL TRATAMIENTO DE LA DIABETES TIPO 1 BASADAS EN LAS ESTRATEGIAS DE SUPERVIVENCIA DE LAS CÉLULAS ALFA PANCREÁTICAS
- In vitro assays to identify metabolism-disrupting chemicals with diabetogenic activity in a mouse pancreatic alpha-cell model
- Intramodal functional plasticity in the developing somatosensory system
- Intramodal functional plasticity in the developing somatosensory system
- Intramodal functional plasticity in the developing somatosensory system
- LA SOBREEXPRESIÓN DE BCL-XL COMO ESTRATEGIA PARA PROTEGER A LAS CÉLULAS BETA PANCREÁTICAS DE LA APOPTOSIS INDUCIDA POR CITOQUINAS PROINFLAMATORIAS EN LA DIABETES TIPO 1
- Modulation of TRPA1 channels by the chaperone Sigma-1Receptor as a neuroprotective strategy against peripheral neuropathy by chemotherapy
- Novel in vitro approaches to study X-linked adrenoleukodystrophy
- PDX1-ALX3-GPR40 axis promotes glucose responsiveness and insulin secretion in pancreatic beta-cells
- Papel de los receptores de estrógenos en la apoptosis de la célula ß pancreática
- Perinatal retinal waves regulate the early functional segregation of sensory modalities via the superior colliculus
- Regulation of potassium ion channels by 17ß-estradiol and the endocrine disruptor Bisphenol-A in the human beta cell line EndoC-ßH1
- Regulation of potassium ion channels by 17ß-estradiol and the endocrine disruptor Bisphenol-A in the human beta cell line EndoC-ßH1
- Role of estrogen receptor B on K channel regulation in the human beta cell line EndoC-ßH1
- Sensory processing of TRPM8-dependent activity contributes to both reflex and spontaneous blink
- Structural and functional abnormalities in the hippocampus caused by Lis1 inactivation in parvalbumin expressing neurons
- Structural and functional insights into TRPM8 modulation mediated by the immunosuppressant macrolide Rapamycin
- Thalamic and somatosensory cortex neurons innervating the ocular surface are multimodal
- The effects of aging on pancreatic ß-cell function involve multiple events in the regulation of insulin secretion.
- Therapeutical approach for a novel in vitro model of X-linked adrenoleukodystrophy
- Validation of the CD11c-DTR transgenic mouse model to study neuroimmune interactions in the cornea
- Vimentin as a regulator of cell survival and endoplasmic reticulum stress in pancreatic alpha and beta cells
- Vimentin as a regulator of cell survival and endoplasmic reticulum stress in pancreatic alpha- and beta-cells
- Why clinical trials on ATMPs do not reach or even fail in phase 3
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external project
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invited conference
- Bilateral changes in corneal sensitivity after unilateral corneal infection
- Combatir el dolor regenerando los nervios sensoriales.
- Endocrine disruptors and beta cells
- Endocrine disruptors and pancreatic beta cells
- Endocrine disruptors as environmental determinants of diabetes mellitus
- Identification of endocrine disruptors with diabetogenic activity using pancreatic beta cells
- Neurobiological basis of ocular neuropathic pain
- Neurobiología del dolor y la analgesia en niños
- Papel de los receptores de estrógenos y de los disruptores endocrinos en la diabetes
- Participación en Horizonte Europa: casos de éxito
- Rol de la inervación ocular en ojo seco
- Unilateral corneal insult also alters sensory nerve activity in the contralateral eye
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operating licence
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patent
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person
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person (active)
- ACOSTA BOJ, MARÍA DEL CARMEN
- BLANQUER GREGORI, JOSE FRANCISCO JAVIER
- CABEDO MARTI, HUGO
- DE LA PEÑA GARCÍA, ELVIRA MARIA
- GALLAR MARTINEZ, JUANA
- GAVILA LATTUR, TERESA
- GEIJO BARRIENTOS, EMILIO CARLOS
- IBAÑEZ BALLESTEROS, JOAQUIN
- MARROQUI ESCLAPEZ, LAURA
- MARTINI , FRANCISCO JOSE
- MESEGUER VIGUERAS, VICTOR MANUEL
- NADAL NAVAJAS, ANGEL
- RIPOLL ORTS, CRISTINA
- SALA PLA, SALVADOR
- SORIA ESCOMS, BERNAT
- VALDEOLMILLOS LOPEZ, MIGUEL ANGEL
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research project
- 101061179
- 101079256
- 19804
- CIPROM/2021/018
- EQC2021-007485-P
- FTPGB18/SMP
- GA 101035817
- GA nº 825489
- GVA-COVID19/2021/047
- IDIFEDER/2021/036
- PID2020-115934RB-I00
- PID2020-117294RB-I00
- PID2020-117569RA-I00
- PID2020-118171RB-I00
- PID2021-124460OB-I00
- PIEU-B/2021/01
- PRODICUMH2022_15
- PROMETEO/2020/006
- PROMETEO/2021/027
- PROMETEO/2021/031
- PROMETEO/2021/052
- RG93172/ARTHUR-FARRAJ/34316
- RTI2018-100994-A-I00
- VIDIF22/84
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technological support
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thesis
- ANÁLISIS COMPARATIVO DEL IMPACTO DEL TIPO DE RESECCIÓN ANATÓMICA TORACOSCÓPICA EN LA MORBIMORTALIDAD POSTOPERATORIA, CURSO PERIOPERATORIO Y SUPERVIVENCIA: SEGMENTOMÍA ANATÓMICA VS LOBECTOMÍA.
- DESCRIPCIÓN CLÍNICA Y GENÉTICA DE LOS PACIENTES CON DIAGNÓSTICO DE CHARCOT-MARIE-TOOTH EN EL ÁREA DE ALICANTE E IDENTIFICACIÓN DE NUEVAS MUTACIONES EN CMT1
- IDENTIFICACIÓN MOLECULAR Y MORFODINÁMICA DE LAS FIBRAS SENSORIALES DE FRIO CORNEALES EN EL RATÓN ADULTO
- NEUROIMMUNE INTERACTIONS IN THE CORNEA: EFFECTS OF RESIDENT DENTRITIC CELL DEPLETION ON COLD NERVE TERMINAL ACTIVITY, BASAL TEARING, AND PAIN
- SENSORY INNERVATION OF THE OCULAR SURFACE: FROM PERIPHERAL NERVES TO BRAIN CORTEX
- Tesis Leticia Pérez Saiz nueva versión