Publicaciones en VIVO

Mapa de la ciencia

Red de Coinvestigador

MANZANARES ROBLES, JORGE

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Catedrático/a de Universidad, Farmacología, Pediatría y Química Orgánica 2011 -
PDI INVESTIGADOR, Instituto de Neurociencias 2005 -
MIEMBRO, Neuropsicofarmacología Traslacional 2015 -
Profesor/a Titular Universidad, Farmacología, Pediatría y Química Orgánica 2007 - 2011
Profesor Titular Universidad, Farmacología, Pediatría y Química Orgánica 2004 - 2007

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selected publications

academic article
- Alterations of BDNF, mGluR5, Homer1a, p11 and excitatory/inhibitory balance in corticolimbic brain regions of suicide decedents. JOURNAL OF AFFECTIVE DISORDERS. 366-376. 2023
- Associations of hypomagnesemia in patients seeking a first treatment of alcohol use disorder. DRUG AND ALCOHOL DEPENDENCE. 109822-109829. 2023
- Cannabidiol regulates behavioral and brain alterations induced by spontaneous alcohol withdrawal. NEUROPHARMACOLOGY. 109549-109557. 2023
- Cannabidiol repairs behavioral and brain disturbances in a model of fetal alcohol spectrum disorder. PHARMACOLOGICAL RESEARCH. 106655-106676. 2023
- Cognitive Alterations in Addictive Disorders: A Translational Approach. BIOMEDICINES. 1796-1851. 2023
- Editorial: Cannabidiol treatment in neurotherapeutic interventions, volume II. FRONTIERS IN PHARMACOLOGY. 163991-163994. 2023
- Emotional Processing and Maltreatment During Childhood as Factors of Vulnerability to Alcohol Abuse in Young Adults. INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION. 1-21. 2023
- Methods to Identify Cognitive Alterations from Animals to Humans: A Translational Approach. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 7653-7686. 2023
- Molecular Changes Associated with Suicide. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 16726-16759. 2023
- Regulation of CorticoThalamic JNK1/2 and ERK1/2 MAPKs and Apoptosis-Related Signaling Pathways in PDYN Gene-Deficient Mice Following Acute and Chronic Mild Stress. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2303-2320. 2023
- Role of CB2 cannabinoid receptor in the development of food addiction in male mice. NEUROBIOLOGY OF DISEASE. 106034-106048. 2023
- Sex differences in the comorbidity of patients seeking a first treatment for Alcohol Use Disorder. INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION. 1-15. 2023
- Unveiling behavioral and molecular neuroadaptations related to the antidepressant action of cannabidiol in the unpredictable chronic mild stress model. FRONTIERS IN PHARMACOLOGY. 117164-117166. 2023
- Biomarkers of the Endocannabinoid System in Substance Use Disorders.. BIOMOLECULES. 1-47. 2022
- CBD-mediated regulation of heroin withdrawal-induced behavioural and molecular changes in mice. ADDICTION BIOLOGY. 1-11. 2022
- Cannabidiol attenuates hypersensitivity and oxidative stress after traumatic spinal cord injury in rats. NEUROSCIENCE LETTERS. 1-6. 2022
- Cannabinoid CB1 Receptor Involvement in the Actions of CBD on Anxiety and Coping Behaviors in Mice. PHARMACEUTICALS. 1-19. 2022
- Diferences in Substance Use Disorders and Other Mental Disorders in Mental Health and Addiction Settings: Sociodemographic, Clinical, Drug Treatment, and Gender Diferences. INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION. 1-19. 2022
- Immunomodulatory Role of CB2 Receptors in Emotional and Cognitive Disorders. . FRONTIERS IN PSYCHIATRY. 1-15. 2022
- Molecular Alterations of the Endocannabinoid System in Psychiatric Disorders.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 1-66. 2022
- Pharmacological strategies for post-traumatic stress disorder (PTSD): From animal to clinical studie. NEUROPHARMACOLOGY. 1-21. 2022
- Role of Cannabinoid CB2 Receptor in Alcohol Use Disorders: From Animal to Human Studies.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 1-18. 2022
- CB2 Receptor Involvement in the Treatment of Substance Use Disorders. BIOMOLECULES. 1-18. 2021
- Cannabidiol Modulates Behavioural and Gene Expression Alterations Induced by Spontaneous Cocaine Withdrawal. . NEUROTHERAPEUTICS. 615-623. 2021
- Cannabidiol and Sertraline Regulate Behavioral and Brain Gene Expression Alterations in an Animal Model of PTSD. FRONTIERS IN PHARMACOLOGY. 1-14. 2021
- Cannabidiol prevents priming- and stress-induced reinstatement of the conditioned place preference induced by cocaine in mice. JOURNAL OF PSYCHOPHARMACOLOGY. 864-874. 2021
- Differences in Gene Expression of Endogenous Opioid Peptide Precursor, Cannabinoid 1 and 2 Receptors and Interleukin Beta in Peripheral Blood Mononuclear Cells of Patients With Refractory Failed Back Surgery Syndrome Treated With Spinal Cord Stimulation: Markers of Therapeutic Outcomes. NEUROMODULATION. 49-60. 2021
- Editorial: Cannabidiol treatment in neurotherapeutic interventions. FRONTIERS IN PHARMACOLOGY. 1-2. 2021
- Editorial: The Search for Biomarkers in Psychiatry. FRONTIERS IN PSYCHIATRY. 720411-720412. 2021
- Pairing Binge Drinking and a High-Fat Diet in Adolescence Modulates the Inflammatory Effects of Subsequent Alcohol Consumption in Mice. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 1-23. 2021
- Relation between Alpha-Synuclein and Core CSF Biomarkers of Alzheimer¿s Disease. MEDICINE. 1-9. 2021
- Role of cannabidiol in therapeutic intervention for substance use disorders. FRONTIERS IN PHARMACOLOGY. 1-24. 2021
- The administration of sertraline plus naltrexone reduces ethanol consumption and motivation in a long-lasting animal model of post-traumatic stress disorder. NEUROPHARMACOLOGY. 1-11. 2021
- Therapeutic potential of the cannabinoid receptor 2 in neuropsychiatry. EXPLORATION OF NEUROPROTECTIVE THERAPY . 55-71. 2021
- Association of cannabinoid receptor genes (CNR1 and CNR2) polymorphisms and panic disorder. ANXIETY STRESS AND COPING. 2020
- Biomarkers in Psychiatry: Concept, Definition, Types and Relevance to the Clinical Reality. FRONTIERS IN PSYCHIATRY. 1-14. 2020
- Cannabidiol Modulates Behavioural and Gene Expression Alterations Induced by Spontaneous Cocaine Withdrawal. NEUROTHERAPEUTICS. 2020
- Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders. BIOMOLECULES. 1-34. 2020
- Cannabis Use in Pregnant and Breastfeeding Women: Behavioral and Neurobiological Consequences. FRONTIERS IN PSYCHIATRY. 1-15. 2020
- Differences in Gene Expression of Endogenous Opioid Peptide Precursor, Cannabinoid 1 and 2 Receptors and Interleukin Beta in Peripheral Blood Mononuclear Cells of Patients With Refractory Failed Back Surgery Syndrome Treated With Spinal Cord Stimulation: Markers of Therapeutic Outcomes?. NEUROMODULATION. 2020
- Endocannabinoid System Components as Potential Biomarkers in Psychiatry. FRONTIERS IN PSYCHIATRY. 1-30. 2020
- Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment?. FRONTIERS IN PSYCHIATRY. 1-17. 2020
- Cannabidiol does not display drug abuse potential in mice behavior.. ACTA PHARMACOLOGICA SINICA. 358-364. 2019
- Gender differences in the effects of cannabidiol on ethanol binge drinking in mice. ADDICTION BIOLOGY. 1-10. 2019
- Measurement of CSF alpha-synuclein improves early differential diagnosis of mild cognitive impairment due to Alzheimer's disease.. JOURNAL OF NEUROCHEMISTRY. 218-230. 2019
- Alterations in gene and protein expression of cannabinoid CB2 and GPR55 receptors in the dorsolateral prefrontal cortex of suicide victims. NEUROTHERAPEUTICS. 796-806. 2018
- Cannabidiol does not display drug abuse potential in mice behavior. ACTA PHARMACOLOGICA SINICA. 1-7. 2018
- Cannabidiol reduces ethanol consumption, motivation and relapse in mice. ADDICTION BIOLOGY. 154-164. 2018
- Cannabidiol regulates behavioural alterations and gene expression changes induced by spontaneous cannabinoid withdrawal. BRITISH JOURNAL OF PHARMACOLOGY. 2676-2688. 2018
- Cannabidiol regulates the expression of hypothalamus-pituitary-adrenal axis-related genes in response to acute restraint stress. JOURNAL OF PSYCHOPHARMACOLOGY. 1379-1384. 2018
- Cannabinoid CB1 and CB2 receptors, and monoacylglycerol lipase gene expression alterations in the basal ganglia of patients with Parkinson's disease. NEUROTHERAPEUTICS. 459-469. 2018
- Deletion of Dlk1 increases the vulnerability to developing anxiety-like behaviors and ethanol consumption in mice. BIOCHEMICAL PHARMACOLOGY. 37-44. 2018
- Effects of cannabidiol plus naltrexone on motivation and ethanol consumption. BRITISH JOURNAL OF PHARMACOLOGY. 3369-3378. 2018
- Pharmacological regulation of cannabinoid CB2 receptor modulates the reinforcing and motivational actions of ethanol. BIOCHEMICAL PHARMACOLOGY. 227-234. 2018
- Role of the endocannabinoid system in drug addiction. BIOCHEMICAL PHARMACOLOGY. 108-121. 2018
- Cannabidiol reduces ethanol consumption, motivation and relapse in mice.. ADDICTION BIOLOGY. 1-11. 2017
- Changes in gene expression and sensitivity of cocaine reward produced by a continuous fat diet. PSYCHOPHARMACOLOGY. 2337-2352. 2017
- Deletion of Dlk2 increases the vulnerability to anxiety-like behaviors and impairs the anxiolytic action of alprazolam. PSYCHONEUROENDOCRINOLOGY. 134-141. 2017
- Different Molecular/Behavioral Endophenotypes in C57BL/6J Mice Predict the Impact of OX1 Receptor Blockade on Binge-Like Ethanol Intake. FRONTIERS IN BEHAVIORAL NEUROSCIENCE. 1-12. 2017
- Disruption of blood-brain barrier integrity in postmortem alcoholic brain: preclinical evidence of TLR4 involvement from a binge-like drinking model.. ADDICTION BIOLOGY. 1103-1116. 2017
- Involvement of the dynorphin/KOR system on the nociceptive, emotional and cognitive manifestations of joint pain in mice.. NEUROPHARMACOLOGY. 315-327. 2017
- Is the Cannabidiol Potentially Useful for the Treatment of Neuropsychiatric and Drug-Use Disorders? . RESEARCH AND REVIEWS IN BIOSCIENCES. 112-115. 2017
- Psychological symptomatology and impaired prepulse inhibition of the startle reflex are associated with cannabis-induced psychosis.. JOURNAL OF PSYCHOPHARMACOLOGY. 1035-1045. 2017
- The Modulation of the Startle Reflex as Predictor of Alcohol Use Disorders in a Sample of Heavy Drinkers: A 4-Year Follow-Up Study.. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 1212-1219. 2017
- The rewarding effects of ethanol are modelated by binge eating of a high-fat diet during adolescence . NEUROPHARMACOLOGY. 219-230. 2017
- Increased Expression of Readthrough Acetylcholinesterase Variants in the Brains of Alzheimer's Disease Patients.. JOURNAL OF ALZHEIMERS DISEASE. 831-841. 2016
- Increased vulnerability to ethanol consumption in adolescent maternal separated mice.. ADDICTION BIOLOGY. 847-858. 2016
- Social defeat in adolescent mice increases vulnerability to alcohol consumption.. ADDICTION BIOLOGY. 87-97. 2016
- Topiramate increases the rewarding properties of cocaine in young-adult mice limiting its clinical usefulness.. PSYCHOPHARMACOLOGY. 3849-3859. 2016
- Association between maltreatment and polydrug use among adolescents. CHILD ABUSE & NEGLECT. 379-389. 2015
- Cannabidiol as a potential treatment for anxiety disorders. NEUROTHERAPEUTICS. 825-836. 2015
- Differential pharmacological regulation of sensorimotor-gating deficit in CB1 knockout mice and associated neurochemical and histological alterations. NEUROPSYCHOPHARMACOLOGY. 2639-2647. 2015
- Evidence against a critical role of CB1 receptors in adaptation of the hypothalamic-pituitary-adrenal axis and other consequences of daily repeated stress. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 1248-1259. 2015
- Gestational and early postnatal hypothyroidism alters VGluT1 and VGAT bouton distribution in the neocortex and hippocampus, and behavior in rats. FRONTIERS IN NEUROANATOMY. 2015
- Increased vulnerability to ethanol consumption in adolescent maternal separated mice. ADDICTION BIOLOGY. 2015
- Reduced contextual discrimination following alcohol consumption or MDMA administration in mice. PLOS ONE. 142978-142995. 2015
- Role of CB2 receptors in social and aggressive behavior in male mice. PSYCHOPHARMACOLOGY. 3019-3031. 2015
- Role of cannabinoid CB2 receptor in the reinforcing actions of ethanol 2015. ADDICTION BIOLOGY. 43-55. 2015
- Role of the endocannabinoid system in the emotional manifestations of osteoarthritis pain. PAIN. 2001-2012. 2015
- Social defeat in adolescent mice increased the vulnerability for alcohol consumption . ADDICTION BIOLOGY. 1-10. 2015
- Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victoms. MOLECULAR NEUROBIOLOGY. 957-965. 2014
- Effects of naltrexone plus topiramate on ethanol self-administration and tyrosine hydroxylase gene expression changes. ADDICTION BIOLOGY. 862-873. 2014
- Regulatory role of the cannabinoid CB2 receptor in stress-induced neuroinflamation in mice. BRITISH JOURNAL OF PHARMACOLOGY. 2814-2826. 2014
- Role of cannabinoid CB2 receptor in the reinforcing actions of ethanol. ADDICTION BIOLOGY. 2014
- Social defeat in adolescent mice increases vulnerability to alcohol consumption. ADDICTION BIOLOGY. 2014
- Abnormal expression pattern of Notch receptors, ligands and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims. MOLECULAR NEUROBIOLOGY. 1-10. 2013
- CB1 cannabinoid receptor-mediated aggressive behavior. NEUROPHARMACOLOGY. 172-180. 2013
- Deletion of CB2 cannabinoid receptors increased voluntary ethanol consumption and ethanol self-administration associated to alterations in tyrosine hydroxylase and mu-opioid receptor in the mice brain. ADDICTION BIOLOGY. 2013
- FKBP5 alterations in the dorsal prefrontal cortex and amygdala of suicide victims . PSYCHONEUROENDOCRINOLOGY. 1251-1258. 2013
- Pregabalin and topiramate regulate behavioral and brain gene transcription changes induced by spontaneous cannabinoid withdrawal in mice . ADDICTION BIOLOGY. 252-262. 2013
- Role of CB2 cannabinoid receptors in the rewarding, reinforcing, and physical effects of nicotine. NEUROPSYCHOPHARMACOLOGY. 2013
- Role of cannabinoid CB1 and CB2 receptors in the development of osteoarthritic pain. PAIN. 160-174. 2013
- Spontaneous Generation of infectious prion disease in transgenic mice. EMERGING INFECTIOUS DISEASES. 1938-1947. 2013
- Synaptic plasticity alterations associated to memory impairment induced by deletion of CB2 cannabinoid receptors . NEUROPHARMACOLOGY. 388-396. 2013
- Synergistic action of naltrexone plus topiramate on ethanol self-administration in C57BL/6 mice and tyrosine hydroxylase gene expression changes in the ventral tegmental area. ADDICTION BIOLOGY. 2013
- Voluntary alcohol drinking enhances proopiomelanocortin (POMC) gene expression in nucleus accumbens shell and hypothalamus of Sardinian alcohol-preferring rats. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 131-140. 2013
- Accumbal dopamine, noradrenaline and serotonin activity after naloxone-conditioned place aversion in morphine-dependent mice.. NEUROCHEMISTRY INTERNATIONAL. 433-440. 2012
- Cannabinoid CB2 receptor-mediated regulation of impulsive-like behaviour in DBA/2 mice. . BRITISH JOURNAL OF PHARMACOLOGY. 260-273. 2012
- Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection. . STROKE. 211-219. 2012
- Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels. . NEUROBIOLOGY OF AGING. 627-637. 2012
- Chronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABA(A) receptors.. BRITISH JOURNAL OF PHARMACOLOGY. 951-964. 2012
- Decreased cocaine motor sensitization and self-administration in mice overexpressing cannabinoid CB¿ receptors. . NEUROPSYCHOPHARMACOLOGY. 1749-1763. 2012
- Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects. . FRONTIERS IN BEHAVIORAL NEUROSCIENCE. 2-23. 2012
- Endogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation. . AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. 565-571. 2012
- Gene and protein alterations of FKBP5 and glucocorticoid receptor in the amygdala of suicide victims. PSYCHONEUROENDOCRINOLOGY. 2012
- Increased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission. . ADDICTION BIOLOGY. 322-337. 2012
- Innate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol-preferring sP rats. . ADDICTION BIOLOGY. 62-75. 2012
- Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine. . NEUROBIOLOGY OF AGING. 4211-42116. 2012
- Overexpression of Cannabinoid CB2 Receptor in the Brain Induces Hyperglycaemia and a Lean Phenotype in Adult Mice.. JOURNAL OF NEUROENDOCRINOLOGY. 1106-1119. 2012
- Pregabalin and topiramate mediated regulation of cognitive and motor impulsivity in DBA/2 mice.. BRITISH JOURNAL OF PHARMACOLOGY. 183-195. 2012
- Pregabalin and topiramate regulate behavioural and brain gene transcription changes induced by spontaneous cannabinoid withdrawal in mice. . ADDICTION BIOLOGY. 1-11. 2012
- Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate.. PAIN. 2012
- Voluntary Alcohol Drinking Enhances Proopiomelanocortin Gene Expression in Nucleus Accumbens Shell and Hypothalamus of Sardinian Alcohol-Preferring Rats.. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 1-10. 2012
- Cannabinoid CB1 receptor regulation of GABA A and GABA B receptors. JOURNAL OF PSYCHOPHARMACOLOGY. 105-110. 2011
- Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels. NEUROBIOLOGY OF AGING. 1-11. 2011
- Deletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors. NEUROPSYCHOPHARMACOLOGY. 1489-504. 2011
- Endocannabinoid system and neuropsychiatry: in search of a neurobiological basis for the ¿two sides of the coin¿. FRONTIERS IN BEHAVIORAL NEUROSCIENCE. 1-21. 2011
- Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors. NEUROBIOLOGY OF AGING. 631-645. 2011
- Overexpression of CB2 cannabinoid receptor gene expression results in decreased vulnerability to anxiety and impaired action of alprazolam in mice. JOURNAL OF PSYCHOPHARMACOLOGY. 111-120. 2011
- Prodynorphin gene deletion increased anxiety-like behaviors, impaired the anxiolytic effect of bromazepam and altered GABAA receptor subunits gene expression in the amygdala. JOURNAL OF PSYCHOPHARMACOLOGY. 87-96. 2011
- The regulatory role of cannabinoid CB1 receptor in stress-induced excitotoxicity and neuroinflammation. NEUROPSYCHOPHARMACOLOGY. 805-818. 2011
- CB1 receptor blockade decreases ethanol intake and associated neurochemical changes in Fawn-Hooded rats. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 131-141. 2010
- Decreased GABAa and GABAb receptor functional activity in cannabinoid CB1 receptor knock out mice. JOURNAL OF PSYCHOPHARMACOLOGY. 2010
- Depression-resistant endophenotype in mice overexpressing cannabinoid CB2 receptors. BRITISH JOURNAL OF PHARMACOLOGY. 1773-1784. 2010
- Innate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol-preferring sP rats. ADDICTION BIOLOGY. 1-17. 2010
- Overexpression of CB2 cannabinoid receptors decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice. JOURNAL OF PSYCHOPHARMACOLOGY. 1-10. 2010
- Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine. NEUROBIOLOGY OF AGING. 1-16. 2010
- Prodynorphin gene deletion increased anxiety-like behaviours, impaired the anxiolytic effect of bromazepam and altered GABAa receptor subunits gene expression in the amygdala. JOURNAL OF PSYCHOPHARMACOLOGY. 1-10. 2010
- Regulation of Fas receptor/Fas-associated protein with death domain apoptotic complex and associated signalling systems by cannabinoid receptors in the mouse brain. BRITISH JOURNAL OF PHARMACOLOGY. 643-656. 2010
- The cannabinoid CB1 receptor is involved in the anxiolytic, sedative and amnesic actions of benzodiazepines. JOURNAL OF PSYCHOPHARMACOLOGY. 757-765. 2010
- Lactacystin requires reactive oxygen species and Bax redistribution to induce mitochondria-mediated cell death. BRITISH JOURNAL OF PHARMACOLOGY. 1121-1130. 2009
- Modulation of impulsivity by topiramate: Implications for the treatment of alcohol dependence. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 584-589. 2009
- Crucial role of CB2 cannabinoid receptor in the regulation of central immune responses during neuropathic pain. JOURNAL OF NEUROSCIENCE. 12125-12136. 2008
- Interferon-gamma is a critical modulator of CB2 cannabinoid receptor signaling during neuropathic pain. JOURNAL OF NEUROSCIENCE. 12136-12145. 2008
- Manipulation of fatty acid amide hydrolase functional activity alters sensitivity and dependence to ethanol. JOURNAL OF NEUROCHEMISTRY. 233-243. 2008
- Métodos de evaluación de trastornos cognitivos en modelos animales. REVISTA DE NEUROLOGIA. 137-145. 2008
- The use of cocaine in heavy drinkers increases the vulnerability for alcohol dependence: A four-year-follow-up study. JOURNAL OF CLINICAL PSYCHIATRY. 563-570. 2008
- Time course effects of acute ethanol administration on opioid and cannabinoid function in selected regions of the rat brain. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 373-382. 2008
- Gene transcription alterations associated to decrease of ethanol intake induced by naltrexone in brain regions of Wistar rats.. NEUROPSYCHOPHARMACOLOGY. 1358-1369. 2007
- Gene transcription alterations associated to decrease of ethanol intake induced by naltrexone in brain regions of Wistar rats. NEUROPSYCHOPHARMACOLOGY. 2006
- Role of the cannabinoid system in pain control and therapeutic implications in the management of acute and chronic pain episodes. CURRENT NEUROPHARMACOLOGY. 239-257. 2006
- The effects of topiramate adjunctive treatment added to antidepressants in patients with resistant obsessive compulsive disorder. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 341-344. 2006
- Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors. EUROPEAN JOURNAL OF PHARMACOLOGY. 9-19. 2005
- Cerebrospinal fluid and plasma neurotransmitter aminoacid levels in patients with dementia with Lewy bodies. JOURNAL OF NEURAL TRANSMISSION. 557-563. 2005
- Effects of repeated administration with CP-55,940, a cannabinoid CB1 receptor agonist on the metabolism of the hepatic heme. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 1620-1625. 2005
- Interactions between the cannabinoid and opioid receptor systems in the mediation of alcohol effects. ALCOHOL AND ALCOHOLISM. 25-34. 2005
- Kappa- and delta-opioid functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice. EUROPEAN JOURNAL OF NEUROSCIENCE. 2106-2110. 2005
- Synthesis and Structure-Activity Relationships of a New Model of Arylpiperazines. 8. Computer-Assisted Design of New 5-HT1AR Agonists with Selectivity over á1-Adrenoceptors. JOURNAL OF MEDICINAL CHEMISTRY. 2548-2558. 2005
- Time course of opioid and cannabinoid gene transcription alterations induced by repeated administration with fluoxetine in the rat brain. NEUROPHARMACOLOGY. 618-626. 2005
- Cannabinoid-opioid crosstalk in the central nervous system. CRITICAL REVIEWS IN NEUROBIOLOGY. 159-172. 2004
- Chronic ethanol consumption regulates cannabinoid CB1 receptor gene expression in selected regions of rat brain. ALCOHOL AND ALCOHOLISM. 88-92. 2004
- Differences in basal cannabinoid CB1 receptor function in selective brain areas and vulnerability to alcohol consumption between Wistar and Fawn Hooded rats. ALCOHOL AND ALCOHOLISM. 297-302. 2004
- Impaired action of anxiolytics in mice deficient in cannabinoid CB1 receptors. NEUROPHARMACOLOGY. 966-973. 2004
- Papel del sistema opioide endógeno en la dependencia alcohólica. Actualizaciones en Neurología, neurociencias y envejecimiento. 262-266. 2004
- Repeated administration of D9-tetrahydrocannabinol produces a differential time-related regulation of µ-opioid receptors in the rat brain.. JOURNAL OF PSYCHOPHARMACOLOGY. 51-55. 2004
- Role of the neuronal cannabinoid system in mental diseases. Neurotoxicity Research. 213-224. 2004
- Spontaneous cannabinoid withdrawal produces differential time-related alterations in cannabinoid CB1 receptor gene expression in the mouse brain. JOURNAL OF PSYCHOPHARMACOLOGY. 57-62. 2004
- Topiramate in the treatment of alcohol dependence: A Case Series. . PHARMACOPSYCHIATRY. 37-40. 2004
- Tratamiento farmacológico de la dependencia nicotínica: nuevas perspectivas. Actualizaciones en Neurología, neurociencias y envejecimiento. 361-365. 2004
book
- Guía de intervención clínica para el manejo del trastorno por uso de alcohol. UNIVERSIDAD MIGUEL HERNANDEZ. 2021
chapter
- Farmacología del alcohol e intoxicación aguda. Drogodependencias 4ª ed. 117-129. 2023
- Biomarkers. Comprehensive pharmacology. 693-724. 2022
- Biomarkers. Reference Module in Biomedical Sciences. 1-31. 2021
- Estrés temprano y sus consecuencias en la vida adulta. Neurobiología del Estrés Temprano. Respuesta del estrés durante la programación de la vida temprana.. 89-106. 2020
- Cannabidiol and Cannabis Use Disorders. Cannabis Use Disorders. 31-42. 2018
- Avances en el tratamiento de los trastornos asociados al uso del cannabis. Avances en Adicciones: Claves para comprender los nuevos retos asistenciales. 33-52. 2010
- Trastorno por ansiedad y adicciones. Tratado de Patologia Dual, Reintegrando la Salud Mental. 531-560. 2010
- Principios generales de diagnóstico y tratamiento. Principios generales de diagnóstico y tratamiento. En: Manual de diagnóstico y terapéutica neurológicos. 1-10. 2007
- LOS MODELOS ANIMALES DE LA ENFERMEDAD MENTAL DESDE LA PERSPECTIVA HISTÓRICA. HISTORIA DE LA PSICOFARMACOLOGIA. Tomo I. 423-445. 2005
- Consideraciones neuroquímicas y conceptuales sobre el diseño de modelos animales de patología dual. Avances Neurocientíficos y Realidad Clínica VIII. Patología Dual. 67-86. 2004
- Farmacologia básica de la gabapentina. Avances en el tratamiento de las adicciones: Bases clínicas para el uso de la gabapentina. 121-134. 2004
- Papel de la gabapentina en el tratamiento de las drogodepencias: mecanismos implicados. Avances en el tratamiento de las adicciones: Bases clínicas para el uso de la gabapentina. 103-117. 2004
congress communication

presentations

invited conference
- Efectos del cannabidiol en la conducta en ratones con trastorno del espectro alcohólico fetal, Conferencia 2023
- Cannabidiol y adicciones, Conferencia 2022
- Complicaciones producidas por consumo de THC durante la gestación y lactancia en roedor, Conferencia 2022
- Complicaciones derivadas del uso de cannabis durante la gestación y lactancia, Conferencia 2022
- Potencial terapéutico del cannabidiol en la adicción, Conferencia 2022
- Cannabidiol y adicciones, Conferencia 2022
- Cannabis paraiso o infierno, Conferencia 2022
- Papel del cannabidiol en el tratamiento de la dependencia por alcohol, Conferencia 2022
- Papel del cannabidiol en la regulación de las drogodependencias, Conferencia 2022
- Complicaciones derivadas del uso de cannabis durante la gestación y lactancia, Conferencia 2022
- Cannabis: Medicamento o droga, Conferencia 2022
- NUEVAS TERAPIAS FARMACOLÓGICAS, Conferencia 2017
- PAPEL DEL RECEPTOR CANNABINOIDE CB2 EN LA TERAPÉUTICA DE LAS ADICCIONES, Conferencia 2017
- TRATAMIENTO DEL ALCOHOLISMO, MECANISMO DE ACCIÓN Y MODELIZACIÓN ANIMAL, Conferencia 2017
- La verdad sobre el cannabis droga o medicamento, Conferencia 2017
- WHY IS TRANSLATIONAL RESEARCH IMPORTANT IN DUAL PATHOLOGY? , Conferencia 2017
- Papel del receptor cannabionoide CB2 en el desarrollo o tratamiento de los trastornos adictivos, Conferencia 2015
- Role of cannabinoid CB2 receptor in the reinforcing actions of ethanol, Conferencia 2015
- Nerurochemical and behavioral changes induced by maternal separation and vulnerability to alcohol consumption in mice, Conferencia 2015
- Therapeutic perspectives of cannabinoid (CBD) in the treatment of Neuropsychiatric disorders, Conferencia 2015
- Role of cannabinoid CB2 receptor in the regulation of emotional processes, Conferencia 2014
- Benefits or harms of the electronic cigarette from a neuropharmacological point of view, Conferencia 2014
- Discovery of the nicotine gene (plenary open lecture), Conferencia 2014
- Papel del receptor cannabinoide CB2 en la regulación de los procesos emocionales, Conferencia 2014
- Cannabis : droga o medicamento, Conferencia 2014
- The role of cannabinoid CB2 receptor in the development of psychotic disorders and drug addiction, Conferencia 2014
- Is the cannabinoid receptor a new target for the treatment of neuropsychiatric diseases ?, Conferencia 2014
- Role of cannabinoid CB2 receptors in the regulation of anxiety and depression, Conferencia 2014
- Is the cannabinoid CB2 receptor a new target for neoropsychiatric diseases ?, Conferencia 2014
- El sistema cannabinoide. Un área en investigación para la mejora de la analgesia, Conferencia 2013
- La investigación en trastornos adictivos, Conferencia 2013
- Papel del receptor cannabinoide CB2 en el refuerzo y motivación por el consumo de nicotina, Conferencia 2013
- Role of cannabinoid CB2 receptors in the development of psychiatric disorders and drug addiction with special focus on vulnerability to alcohol and nicotine consumption. NIDA symposium, Conferencia 2013
- Papel del receptor cannabinoide CB2 en las patologías psiquiátricas y en los trastornos adictivos, Conferencia 2013
- Papel del receptor cannabinoide CB2 en refuerzo y motivación por el consumo de alcohol y nicotina, Conferencia 2013
- Papel del receptor cannabinoide CB2 en la regulación de los procesos afectivos, Conferencia 2013
- Genética y comportamientos adictivos: desde la investigación básica a la clínica papel del receptor CB1 en la regulación del efecto de las benzodiacepinas, Conferencia 2009
- Enfermedades neurodegenerativas y alteraciones motoras de origen central: enfermedad de Parkinson , Conferencia 2006
- Cannabis:droga o medicamento, Conferencia 2006
- Cannabis como drogas de abuso y agentes terapéuticos, Conferencia 2006
- Sistema endocannabinoide y sus funciones, Conferencia 2006
- Papel de los sistemas opioide y cannabinoide en la vulnerabilidad por el consumo de alcohol y el tratamiento de la deshabituación en modelos animales, Conferencia 2006
- Modelos animales en el estudio de las alteraciones cognitivas, Conferencia 2006
- Cannabis:droga o medicamento, Conferencia 2006
- Papel del receptor cannabinoide CB1 en la vulnerabilidad por la lesión por 6-OHDA y en el desarrollo de movimientos involuntarios anormales tras el tratamiento con L-DOPA, Conferencia 2006
- 7ª SEMANA de la CIENCIA y la TECNOLOGÍA: "Cannabis:Droga o Medicamento", Conferencia 2005
- Jornada sobre tratamiento e investigación en drogodependencias, Conferencia 2005
- Forum Científico de la Fundación la Caixa, Conferencia 2005
- World Psychiatric Association, International Congress, Treatments in Psychiatry: an Update, Conferencia 2004
- Cursos de Verano de la Fundación General de la Universidad Complutense, Conferencia 2004
- Avances Neurocientíficos y realidad Clínica. Patología Dual., Conferencia 2004
- ESBRA NORDMANN AWARD MEETING 2004ALCOHOL AND CANNABIS from basic to clinical research, Conferencia 2004
- Master in Etología Clínica y Bienestar Animal. ¿Modelos animales en Psiquiatría¿., Conferencia 2004
- XXXIX Congreso de la Sociedad Española de Medicina Psicosomática, Conferencia 2004
- II Congreso Nacional de Ansiedad y Trastornos Comórbidos. Hotel Princesa Sofía, Conferencia 2004