Publicaciones en VIVO

Mapa de la ciencia

ESTEPA PEREZ, MARIA AMPARO

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Positions

MIEMBRO, ESTRATEGIAS ANTIVIRALES 2012 - 2017
PDI INVESTIGADOR, Instituto de Biología Molecular y Celular 2004 - 2015
Catedrático/a de Universidad, Bioquímica y Biología Molecular 2010 - 2015
SUBDIRECTOR/A DE INSTITUTO, Instituto de Biología Molecular y Celular 2011 - 2015
Profesor/a Titular Universidad, Bioquímica y Biología Molecular 2007 - 2010
Profesor Titular Universidad, Bioquímica y Biología Molecular 2000 - 2007
Profesor Titular Universidad, DPTO. NEUROQUIMICA 1999 - 2000
Profesor Interino Titular Unv., DPTO. NEUROQUIMICA 1997 - 1999

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supported publications or other works

selected publications

academic article
- Induction of viral interference by IPNV-carrier cells on target cells: a cell co-culture study. FISH & SHELLFISH IMMUNOLOGY. 483-489. 2016
- Structure and functionalities of the human c-reactive protein compared to the zebrafish multigene family of c-reactive-like proteins. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 33-40. 2016
- Autophagy-inducing peptides from mammalian VSV and fish VHSV rhabdoviral G glycoproteins (G) as models for the development of new therapeutic molecules. AUTOPHAGY. 1666-1680. 2014
- In addition to its antiviral and immunomodulatory properties, the zebrafish ß-defensin 2 (zfBD2) is a potent viral DNA vaccine molecular adjuvant. . ANTIVIRAL RESEARCH. 136-147. 2014
- Targeting and stimulation of the zebrafish (Danio rerio) innate immune system with LPS/dsRNA-loaded nanoliposomes. VACCINE. 3955-3962. 2014
- Transcriptome profiles associated to VHSV infection or DNA vaccination in turbot (Scophthalmus maximus). PLOS ONE. 104509-104515. 2014
- VHSV G glycoprotein major determinants implicated in triggering the host type I IFN antiviral response as DNA vaccine molecular adjuvants.. VACCINE. 6012-6019. 2014
- Antiviral activity produced by an IPNV-carrier EPC cell culture confers resistance to VHSV infection. VETERINARY MICROBIOLOGY. 412-418. 2013
- Behavioural fever is a synergic signal amplifying the innate immune response. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. 201313-201320. 2013
- Identification of Multipath Genes Differentially Expressed. PLOS ONE. 73553-73563. 2013
- Improving the safety of viral DNA vaccines: development of vectors containing both 5 and 3 homologous regulatory sequences. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 3007-3016. 2013
- In Vitro Neutralization of Viral Hemorrhagic Septicemia Virus by plasma from innunized zebrafish. ZEBRAFISH. 43-52. 2013
- Increasing Versatility of the DNA Vaccines through Modification of the Subcellular Location of Plasmid-Encoded Antigen Expression in the In Vivo Transfected Cells. PLOS ONE. 1-12. 2013
- Melittin-loaded immunoliposomes against viral surface proteins, a new approach to antiviral therapy. ANTIVIRAL RESEARCH. 218-221. 2013
- Optimization of fixed-permeabilized cell monolayers for high. JOURNAL OF VIROLOGICAL METHODS. 627-632. 2013
- Stabilization of neutral Polyfluorenein aqueous solution through their interaction with phospholipids and sol-gel encapsulation.. ACS APPLIED MATERIALS & INTERFACES. 2952-2958. 2013
- pH-dependent solution structure and activity of the host-defense peptide myticin C (Myt C) from the mussel Mytilus galloprovincialis.. MARINE DRUGS. 2328-2346. 2013
- Ex vivo transfection of trout pronephros leukocytes, a model for cell culture screening of fish DNA vaccine candidates.. VACCINE. 5983-5990. 2012
- Improving the safety of viral DNA vaccines: development of vectors containing both 5' and 3' homologous regulatory sequences from non-viral origin. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2012
- Protection and antibody response induced by intramuscular DNA vaccine encoding for viral haemorrhagic septicaemia virus (VHSV) G glycoprotein in turbot (Scophthalmus maximus). FISH & SHELLFISH IMMUNOLOGY. 1088-1094. 2012
- Replacement of the human cytomegalovirus promoter with fish enhancer and core elements to control the expression of the G gene of viral haemorrhagic septicemia virus (VHSV).. JOURNAL OF BIOTECHNOLOGY. 171-178. 2012
- A comparative review on European-farmed finfish RNA viruses and their vaccines. VACCINE. 2657-2671. 2011
- An ELISA for detection of trout antibodies to viral haemorrhagic septicemia virus using recombinant fragments of their viral G protein. JOURNAL OF VIROLOGICAL METHODS. 14-23. 2011
- Antibody recognition of the glycoprotein g of viral haemorrhagic septicemia virus (VHSV) purified in large amounts from insect larvae . BIOMED CENTRAL RESEARCH NOTES. 210-217. 2011
- Characterization of an infectious pancreatic necrosis (IPN) virus carrier cell culture with resistance to superinfection with heterologous viruses. VETERINARY MICROBIOLOGY. 48-55. 2011
- In vitro analysis of the factors contributing to the antiviral state induced by a plasmid encoding the viral haemorrhagic septicaemia virus glycoprotein G in transfected trout cells. VACCINE. 737-743. 2011
- Mytilus galloprovincialis Myticin C: A Chemotactic Molecule with Antiviral Activity and Immunoregulatory Properties. PLOS ONE. 23140-2354. 2011
- Rainbow trout surviving infections of viral haemorrhagic septicemia virus (VHSV) show lasting antibodies to recombinant G protein fragments . FISH & SHELLFISH IMMUNOLOGY. 929-935. 2011
- The introduction of multi-copy CpG motifs into an antiviral DNA vaccine strongly up-regulates its immunogenicity in fish. VACCINE. 1289-1296. 2011
- Pepscan mapping of Viral Haemorrhagic Septicaemia virus (VHSV) glycoprotein G major lineal determinants implicated in triggering host cell antiviral responses mediated by type I IFN. JOURNAL OF VIROLOGY. 1234-1240. 2010
- Zebrafish fin immune responses during high mortality infections with viral haemorrhagic septicemia rhabdovirus. A proteomic and transcriptomic approach. BMC GENOMICS. 518-533. 2010
- Antimicrobial Peptides as Model Molecules for the Development of Novel antiviral agents in aquaculture . MINI-REVIEWS IN MEDICINAL CHEMISTRY. 1159-1164. 2009
- New tools to study RNA interference to fish viruses: Fish cell lines permanently expressing siRNAs targeting the viral polymerase of viral hemorrhagic septicemia virus. ANTIVIRAL RESEARCH. 148-156. 2009
- Nodavirus Infection of Sea Bass (Dicentrarchus labrax) Induces Up-Regulation of Galectin-1 Expression with Potential Anti-Inflammatory Activity.. JOURNAL OF IMMUNOLOGY. 6600-6611. 2009
- The immunogenicity of viral haemorragic septicaemia rhabdovirus (VHSV) DNA vaccines can depend on plasmid regulatory sequences. VACCINE. 1938-1948. 2009
- The rainbow trout TLR9 gene and its role in the immune responses elicited by a plasmid encoding the glycoprotein G of the viral haemorrhagic septicaemia rhabdovirus (VHSV).. MOLECULAR IMMUNOLOGY. 1710-1717. 2009
- Transfection improvements of fish cell lines by using deacylated polyethylenimine of selected molecular weights. FISH & SHELLFISH IMMUNOLOGY. 559-566. 2009
- Expression and antiviral activity of a ß-defensin-like peptide identified in the rainbow trout (Oncorhynchus mykiss) EST sequences. MOLECULAR IMMUNOLOGY. 757-765. 2008
- In vitro search for alternative promoters to the human immediate early cytomegalovirus (IE-CMV) to express the G gene of viral haemorrhagic septicemia virus (VHSV) in fish epithelial cells. . VACCINE. 6620-6629. 2008
- In vivo modulation of the rainbow trout (Oncorhynchus mykiss) immune response by the human alpha defensin-1, HNP1. FISH & SHELLFISH IMMUNOLOGY. 102-112. 2008
- Inhibitory effect of mycophenolic acid on the replication of infectious pancreatic necrosis virus and viral hemorrhagic septicemia virus.. ANTIVIRAL RESEARCH. 332-338. 2008
- Regulation of rainbow trout (Oncorhynchus mykiss) interleukin 8 receptor (IL-8R) gene transcription in response to viral hemorrhagic septicemia virus (VHSV), DNA vaccination and chemokines. FISH & SHELLFISH IMMUNOLOGY. 271-280. 2008
- Assessment of the inhibitory effect of ribavirin on the rainbow trout rhabdovirus VHSV by real-time reverse-transcription PCR. . VETERINARY MICROBIOLOGY. 52-60. 2007
- Dual antiviral activity of human alpha-defensin-1 against viral haemorrhagic septicaemia rhabdovirus (VHSV): inactivation of virus particles and induction of a type I interferon-related response. . ANTIVIRAL RESEARCH. 111-123. 2007
- In vitro and in vivo differential expression of rainbow trout (Oncorhynchus mykiss) Mx isoforms in response to viral haemorrhagic septicaemia virus (VHSV) G gene, poly I:C and VHSV. . FISH & SHELLFISH IMMUNOLOGY. 210-221. 2007
- Fish transposons and its potential use in aquaculture. JOURNAL OF BIOTECHNOLOGY. 397-412. 2006
- Identification of selective inhibitors of VHSV from biased combinatorial libraries of N,N¿-disubstituted 2,5- piperazinediones. ANTIVIRAL RESEARCH. 107-115. 2006
- Rapid detection and quantitation of viral hemorrhagic septicemia virus in experimentally challenged rainbow trout by real-time RT-PCR.. JOURNAL OF VIROLOGICAL METHODS. 154-159. 2006
- Stable expression of bioactive recombinant pleurocidin. in a fish cell line. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 1217-1228. 2006
- Differential effects of oleuropein, a biophenol from Olea europaea, on anionic and zwiterionic phospholipid model membranes. CHEMISTRY AND PHYSICS OF LIPIDS. 2-17. 2005
- Futuro de la vacunas ADN frente a virus en Acuicultura. AquaTIC. 20-35. 2005
- Rapid detection and quantitation of viral hemorrhagic septicemia virus in experimentally challenged rainbow trout by real-time RT-PCR. JOURNAL OF VIROLOGICAL METHODS. 154-159. 2005
- The olive leaf extract exhibits antiviral activity against viral haemorhagic septicaemia virus (VHSV). ANTIVIRAL RESEARCH. 129-136. 2005
- Membrane- related effects underlying the biological activity of the anthraquinones emodin and barbaloin. BIOCHEMICAL PHARMACOLOGY. 549-561. 2004
- Reversible inhibition of spreading of in vitro infection and imbalance of viral protein accumulation at low pH in VHSV, a salmonid rhabdovirus. JOURNAL OF VIROLOGY. 1936-1944. 2004
- Review on the application of inducible and targeted gene-strategies to produce transgenic fish.. MARINE BIOTECHNOLOGY. 118-127. 2004
- Fish as biofactories: inducible genetic systems and gene targeting. SPANISH JOURNAL OF AGRICULTURAL RESEARCH. 3-11. 2003
- New applications of herbal extracts for functional food and pharmaceuticals. Part 1. AGRO FOOD INDUSTRY HI-TECH. 62-64. 2003
- New applications of herbal extracts for functional food and pharmaceuticals. Part 2. AGRO FOOD INDUSTRY HI-TECH. 14-16. 2003
- Antibody response to a linear epitope of the protein G of a rhabdovirus in immunized trout.. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY. 89-99. 2002
- Enhanced detection of viral hemorrhagic septicemia virus (a salmonid rhabdovirus) by pretreatment of the virus with a combinatorial library-selected peptide.. JOURNAL OF VIROLOGICAL METHODS. 17-23. 2002
- A protein G fragment from the salmonid VHS rhabdovirus induces cell-to-cell fusion and membrane phosphatidylserine translocation at low pH?. JOURNAL OF BIOLOGICAL CHEMISTRY. 46268-46275. 2001
- Transfection of epitheloma papulosum cyprini (EPC) carp cells.. BIOTECHNOLOGY LETTERS. 481-487. 2001
book
- Antigenicity and Immunogenicity of the Envelope Glycoprotein (gpG) of Viral Haemorrhagic Septicaemia Rhabdovirus (VHSV). NOVA SCIENCE PUBLISHERS INC. 2011
- Actividad antiviral de un extracto de hoja de olivo frente al virus de la septicemia hemorrágica (VHSV), un rhabdovirus de Salmónidos. Aplicaciones en acuicultura.. MINISTERIO DE AGRICULTURA Y PESCA, ALIMENTACION Y MEDIO AMBIENTE. 2005
chapter
- Potential for antimicrobial peptides to improve health in fish farming. In Infectious disease in aquaculture: prevention and control. 457-479. 2012
- Antigenicity and Immunogenicity of the Envelope Glycoprotein(gpG) of Viral Haemorrhagic Septicaemia Rhabdovirus (VHSV). Immunogenicity. 25-46. 2011
- Possible Applications to Aquaculture of Salmonid Sleeping Beauty Transposon Vectors. Dynamic Biochemistry, Process Biotechnology and Molecular Biology: Aquaculture II. 12-20. 2011
- New Vaccination Strategies for the Improvement of DNA Vaccines Against Virus in Fish. Vaccinations: Types, Potential Complications and Health Effects. 205-227. 2010
- The Relationship between OleuropeinAntimicrobial Activity and its Effects onBiological Membranes. Olives and Olive Oil in Health and Disease Prevention. 1345-1354. 2010
- Defence mechanims againts viral infections in fish: the trout/ viral haemorrhagic septicaemia (VHSV) rhabdovirus model. : Fish Defences Volume 2: Pathogens, Parasites and Predators . 63-109. 2009
- New vaccination strategies for the improvement DNA vaccines against virus in fish. Aquaculture Research Trends. 165-200. 2007
- Towards new fluorescent bio-inspired sensors: interaction of poly(fluorene-phenylene) with phospholipid bilayers. Bioengineered and Bioinspired Systems III . 131-138. 2007
- Modelos de Vacunación y mejora del diagnóstico vírico. Inmunología e Inmunopatología en Piscicultura. 87-96. 2005
congress communication
patent
- PÉPTIDOS ACTIVADORES DE LA INFECTIVIDAD DEL RHABDOVIRUS DE LA SEPTICEMIA HEMORRÁGICA VÍRICA (VHSV)
- Vacuna Recombinante frente al virus de la septicemica hemorrágica vírica

presentations

invited conference
- Autophagy-inducing peptides from rhabdoviral G glycoproteins (G) as models for the development of new therapeutic molecules, Conferencia 2014
- Del veneno al farmaco, Conferencia 2014
- Virus de peces con repercusion en Acuicultura, Conferencia 2007
- Curso, Conferencia 2006
- Cursos de verano de la Universidad del Mar, Conferencia 2004
- Ciclo Anual de Seminarios Científicos, Conferencia 2004
- Expresión de pleurocidina, un péptido antimicrobiano, en lineas celulares, Conferencia 2003