selected publications
-
academic article
- Effects of silver nanoparticles on T98G human glioblastoma cells. TOXICOLOGY AND APPLIED PHARMACOLOGY. 115178-115194. 2020
- Case study: Is bisphenol S safer than bisphenol A in thermal papers?. ARCHIVES OF TOXICOLOGY. 2019
- Interactions of human butyrylcholinesterase with phenylvalerate and acetylthiocholine as substrates and inhibitors: kinetic and molecular modeling approaches. ARCHIVES OF TOXICOLOGY. 1281-1296. 2019
- Albumin, the responsible protein of the Cu(2+)-dependent hydrolysis of O-hexyl O-2,5-dichlorophenyl phosphoramidate (HDCP) by chicken serum "antagonistic stereoselectivity". FOOD AND CHEMICAL TOXICOLOGY. 523-527. 2018
- Analysis of the neurotoxic effects of neuropathic organophosphorus compounds in adult zebrafish. SCIENTIFIC REPORTS. 1-14. 2018
- Cholinesterase and phenyl valerate-esterase activities sensitive to organophosphorus compounds in membranes of chicken brain. TOXICOLOGY. 73-82. 2018
- Copper-dependent hydrolysis of trichloronate by turkey serum studied with use of new analytical procedure based on application of chiral chromatography and UV/Vis spectrophotometry. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND L. 203-209. 2018
- Hydrolyzing activities of phenyl valerate sensitive to organophosphorus compounds paraoxon and mipafox in human neuroblastoma SH-SY5Y cells. TOXICOLOGY. 123-128. 2018
- Copper activation of organophosporus compounds detoxication by chicken serum. FOOD AND CHEMICAL TOXICOLOGY. 417-423. 2017
- Phenyl valerate esterase activity of human butyrylcholinesterase. ARCHIVES OF TOXICOLOGY. 3295-3305. 2017
- Acetylcholine-hydrolyzing activities in soluble brain fraction: Characterization with reversible and irreversible inhibitors. CHEMICO-BIOLOGICAL INTERACTIONS. 374-381. 2016
- Aluminium, nickel, cadmium and lead in candy products and assessment of daily intake by children in Spain.. FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE. 66-71. 2016
- Butyrylcholinesterase identification in a phenylvalerate esterase¿enriched fraction sensitive to low mipafox concentrations in chicken brain. ARCHIVES OF TOXICOLOGY. 2016
- Edtorial. Special Issue. CHEMICO-BIOLOGICAL INTERACTIONS. 49-50. 2016
- Effects of mipafox, paraoxon, chlorpyrifos and its metabolite chlorpyrifos-oxon, on the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells. CHEMICO-BIOLOGICAL INTERACTIONS. 368-373. 2016
- Esterases hydrolyze phenyl valerate activity as targets of organophosphorus compounds. CHEMICO-BIOLOGICAL INTERACTIONS. 358-367. 2016
- Neurotoxic Effects Associated with Current Uses of Organophosphorus Compounds. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY. 809-825. 2016
- New insights on molecular interactions of organophosphorus pesticides with esterases. TOXICOLOGY. 2016
- Roles of NTE protein and encoding gene in development and neurodevelopmental toxicity. CHEMICO-BIOLOGICAL INTERACTIONS. 352-357. 2016
- Aluminium, nickel, cadmium and lead in candy products and assessment of daily intake by children in Spain. FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE. 1-21. 2015
- Expression of biomarker genes of differentiation in D3 mouse embryonic stem cells after exposure to different embryotoxicant and non-embryotoxicant model chemicals. DATA IN BRIEF. 354-365. 2015
- RNA transcripts for the quantification of differentiation allow marked improvements in the performance of embryonic stem cell test (EST). TOXICOLOGY LETTERS. 60-69. 2015
- Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches. ARCHIVES OF TOXICOLOGY. 1-14. 2015
- An integrated approach for detecting embryotoxicity and developmental toxicity of environmental contaminants using in vitro alternative methods.. TOXICOLOGY LETTERS. 356-367. 2014
- Cholinesterase assay by an efficient time end-point method. METHODSX. 258-263. 2014
- Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 905-926. 2014
- Interaction between substrates suggests a relationship between organophosphorus-sensitive phenylvalerate-and acetylcholine-hydrolyzing activities in chicken brain. TOXICOLOGY LETTERS. 132-138. 2014
- Organophosphorus pesticide chlorpyrifos and its metabolites alter the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells in a comparable way to other model neurodevelopmental toxicants. CHEMICAL RESEARCH IN TOXICOLOGY. 1487-1495. 2014
- Separating esterase targets of organophosphorus compounds in thebrain by preparative chromatography. TOXICOLOGY LETTERS. 167-176. 2014
- Silencing of PNPLA6, the Neuropathy Target Esterase (NTE) codifying gene, alters neurodifferentiation of human embryonal carcinoma stem cells (NT2). NEUROSCIENCE. 54-67. 2014
- Stereospecific hydrolysis of a phosphoramidate used as an OPIDP model by human sera with PON1 192 alloforms. ARCHIVES OF TOXICOLOGY. 2014
- Cytotoxic effect against 3T3 fibroblasts cells of saffron floral bio-residues extracts. FOOD CHEMISTRY. 55-59. 2013
- Functional pathways altered after silencing Pnpla6 (the codifying gene of Neuropathy Target Esterase) in mouse embryonic stem cells under differentiation. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL. 2013
- Kinetic interactions of a neuropathy potentiator (phenylmethylsulfonyl fluoride) with the neuropathy target esterase and other membrane bound esterases. ARCHIVES OF TOXICOLOGY. 1-12. 2013
- Cell differentiation markers as endpoints for in vitro developmental toxicity assays. TOXICOLOGY LETTERS. 10-11. 2012
- Characterization and Evolution of Exposure to Volatile Organic Compounds in the Spanish Shoemaking Industry over a 5-Year Period. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE. 653-662. 2012
- Chlorpyrifos and its metabolites alter gene expression at non-cytotoxic concentrations in D3 mouse embryonic stem cells under in vitro differentiation. Considerations for embryotoxic risk assessment.. TOXICOLOGY LETTERS. 2012
- Interactions of neuropathy inducers and potentiators/promoters with soluble esterases. CHEMICO-BIOLOGICAL INTERACTIONS. 2012
- Kinetics of inhibition of soluble peripheral nerve esterases by PMSF: a non-stable compound that potentiates the organophosphorus-induced delayed neurotoxicity. ARCHIVES OF TOXICOLOGY. 767-777. 2012
- NTE and non-NTE esterases in brain membrane: kinetic characterization with organophosphates. TOXICOLOGY. 17-25. 2012
- Phenylmethylsulfonyl Fluoride, a Potentiator of Neuropathy, Alters the Interaction of Organophosphorus Compounds with Soluble Brain Esterases. CHEMICAL RESEARCH IN TOXICOLOGY. 1-9. 2012
- Cell viability effects and antioxidant and antimicrobial activities of tunisian date syrup (Rub El Tamer) polyphenolic extracts.. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 402-406. 2011
- Chlorpyrifos and its metabolite, chlorpyrifos-oxon, modify the genic expression of mouse embryonic stem cells after 12 h of exposure. TOXICOLOGY LETTERS. 157-157. 2011
- Inhibition with spontaneous reactivation of carboxyl esterases by organophosphorus compounds - paraoxon as a model. CHEMICAL RESEARCH IN TOXICOLOGY. 135-143. 2011
- Kinetics of the inhibitory interaction of organophosphorus neuropathy inducers and non-inducers in soluble esterases in the avian nervous system. TOXICOLOGY AND APPLIED PHARMACOLOGY. 360-368. 2011
- Shortening and improving the embryonic stem cell test through the use of gene biomarkers of differentiation. JOURNAL OF TOXICOLOGY. 1-8. 2011
- An alternative in vitro method for detecting neuropathic compounds based on acetylcholinesterase inhibition and on inhibition and aging of Neuropathy Target Esterase (NTE). TOXICOLOGY IN VITRO. 942-952. 2010
- Expression of Neuropathy Target Esterase (NTE) in mouse embryonic stem cells during differentiation. ARCHIVES OF TOXICOLOGY. 481-491. 2010
- Inhibition and spontaneous reactivation of esterases by organophosphorus compounds in presence of the substrate: Paraoxon as a model. TOXICOLOGY LETTERS. 320-321. 2010
- Inhibition with Spontaneous Reactivation of Carboxyl Esterases by Organophosphorus Compounds: Paraoxon as a Model. CHEMICAL RESEARCH IN TOXICOLOGY. 2010
- Inhibition with spontaneous reactivation and the ¿ongoing inhibition¿ effect of. CHEMICO-BIOLOGICAL INTERACTIONS. 397-402. 2010
- Role of albumin in the detoxication of organophosphorus and carbamate pesticides. TOXICOLOGY LETTERS. 31-32. 2010
- Serum albumins and detoxication of anti-cholinesterase agents. CHEMICO-BIOLOGICAL INTERACTIONS. 325-339. 2010
- Caracterización parcial de la esterasa diana de neuropatía en células madre embrionarias de ratón. REVISTA DE TOXICOLOGIA. 33-33. 2009
- Improved analytical method for monitoring exposure to volatile compounds for occupational risk prevention. TOXICOLOGY LETTERS. 261-262. 2009
- Model equations for kinetic of covalent irreversible enzyme inhibition and spontaneous reactivation: esterases and organophosphorus compounds. CRITICAL REVIEWS IN TOXICOLOGY. 427-448. 2009
- Mouse embryonic stem cells for testing the role of neuropathy target esterase in embryogenesis. ALTEX-ALTERNATIVEN ZU TIEREXPERIMENTEN. 326-326. 2009
- Neuropathy Target Esterase in mouse embryonic stem cells. TOXICOLOGY LETTERS. 565-565. 2009
- Serum albumin, and not lipoprotein paraoxonase, is the responsible of the paraoxon detoxication at in vivo toxicologically relevant conditions. TOXICOLOGY LETTERS. 111-111. 2009
- Human serum albumin hydrolyzes the organophosphorus insecticides paraoxon, diazoxon, chlorpyrifos-oxon and O-hexyl O-2,5-dichlorophenyl phosphoramidate. TOXICOLOGY LETTERS. 29-29. 2008
- Serum albumin is as efficient as paraxonase in the detoxication of paraoxon at toxicological relevant concentrations. CHEMICAL RESEARCH IN TOXICOLOGY. 1524-1529. 2008
- A simple and rapid HPLC-MS method for the simultaneous determination of epinephrine, norepinephrine, dopamine and 5-hydroxytryptamine: application to the secretion of bovine chromaffin cell cultures.. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND L. 88-94. 2007
- Albúmina de suero humano hidroliza paraoxon ¿in vitro¿. REVISTA DE TOXICOLOGIA. 131-131. 2007
- Albúmina es la proteína responsable de la destoxicación de carbaryl en suero in vivo. REVISTA DE TOXICOLOGIA. 131-131. 2007
- An in vitro approach for demonstrating the critical role of serum albumin in the detoxication of the carbamate carbaryl at in vivo toxicologically relevant concetrations. ARCHIVES OF TOXICOLOGY. 113-119. 2007
- Characterization of the Paraoxonase-like Activity Associated to Human Serum Albumin. TOXICOLOGY LETTERS. 237-237. 2007
- Comparative hydrolysis of O-hexyl O-2,5-dichlorophenyl phosphoramidate and paraoxon in different tissues of vertebrates. ARCHIVES OF TOXICOLOGY. 689-695. 2007
- Inhibición por mipafox de la actividad fenilvalerato esterasa en fracción particulada de medula adrenal bovina durante el tiempo de reacción enzima sustrato. REVISTA DE TOXICOLOGIA. 131-131. 2007
- Over-expression of neuropathy target esterase activity in bovine chromaffin cell cultures by adenovirus-mediated gene transfer. TOXICOLOGY LETTERS. 286-291. 2007
- Plasma phenylacetate and 1-naphthyl acetate hydrolyzing activities of wild birds as possible non-invasive biomarkers of exposure to organophosphorus and carbamate insecticides. TOXICOLOGY LETTERS. 278-285. 2007
- Recovery of neuropathy target esterase activity after inhibition with mipafox and O-hexyl O-2,5-dichlorophenyl phosphoramidate in bovine chromaffin cell cultures. CHEMICO-BIOLOGICAL INTERACTIONS. 99-105. 2007
- Stereospecific hydrolysis of a phosphoramidate as a model to understand the role of biotransformation in the neurotoxicity of chiral organophosphorus compounds. TOXICOLOGY LETTERS. 157-164. 2007
- Comparison of chromaffin cells from several animal sources for their use as an in vitro model to study the mechanism of organophosphorus toxicity. TOXICOLOGY LETTERS. 221-229. 2006
- Plasmidic vector of human neuropathy target esterase in primary cultures of bovine chromaffin cells. TOXICOLOGY LETTERS. 207-208. 2006
- Preliminar characterization of carboxylesterase activities found in plasma of wild birds. TOXICOLOGY LETTERS. 157-157. 2006
- Role of albumin in the detoxication of the carbamate carbaryl. TOXICOLOGY LETTERS. 65-65. 2006
- Análisis cinético de la interacción con paraoxon de las carboxilesterasas solubles de nervio periférico: evidencia de su rápida reactivación espontánea in vivo. REVISTA DE TOXICOLOGIA. 124-124. 2005
- Análisis de la citotoxicidad de compuestos organofosforados sobre cultivos primarios de células cromafines bovinas.. REVISTA DE TOXICOLOGIA. 134-134. 2005
- Caracterización parcial de actividades carboxilesterasa de plasma de aves silvestres. REVISTA DE TOXICOLOGIA. 134-134. 2005
- Design of a chromatografic method for studying the effect of xenobiotics on the secretion of neurotransmitters. TOXICOLOGY LETTERS. 216-216. 2005
- Influencia del consumo de sustancias en el metabolismo de metadona: Inducción de CYP2B6. REVISTA DE TOXICOLOGIA. 127-127. 2005
- Monitorización terapéutica de R-metadona: Interacción farmacológica entre nevirapina, efavirenz y metadona. REVISTA DE TOXICOLOGIA. 127-127. 2005
- Posible papel de las carboxilesterasas de suero como biomarcadores de la inhibición in vivo de las carboxilesterasas solubles de nervio periférico por compuestos promotores de axonopatías. REVISTA DE TOXICOLOGIA. 124-125. 2005
- Vector plasmídico de la esterasa diana de neuropatía humana en cultivo primario de células cromafines bovinas. REVISTA DE TOXICOLOGIA. 97-97. 2005
- Bovine chromaffin cell cultures as model to study organophosphorus neurotoxicity. TOXICOLOGY LETTERS. 163-170. 2004
- Bovine chromaffin cell cultures as model to study organophosphorus neurotoxicity. TOXICOLOGY LETTERS. 163-170. 2004
- Detection of clinical interactions between methadone and anti-retroviral compounds using an enantioselective capillary electrophoresis for methadone analysis. TOXICOLOGY LETTERS. 243-249. 2004
- Future applications of phosphotriesterases in the prophylaxis and treatment of organophosphorus insecticide and nerve agent poisonings . TOXICOLOGY LETTERS. 219-233. 2004
- Human serum albumin hydrolyses the carbamate carbaryl. TOXICOLOGY AND APPLIED PHARMACOLOGY. 270-270. 2004
- Hydrolysis of carbaryl by human serum albumin. ARCHIVES OF TOXICOLOGY. 629-634. 2004
- Mipafox treatment increases the 5-HT secretion in bovine chromaffin cells cultures. TOXICOLOGY AND APPLIED PHARMACOLOGY. 293-294. 2004
- Mipafox treatment increases the 5-HT secretion in bovine crhomaffin cells cultures. TOXICOLOGY AND APPLIED PHARMACOLOGY. 293-294. 2004
- Nuevas perspectivas en los tratamientos de intoxicaciones por insecticidas organofosforados y agentes nerviosos de guerra.. REVISTA DE NEUROLOGIA. 739-747. 2004
- Spontaneous recuperation of neuropathy target esterase activity after treatment with mipafox and O-hexyl O-2,5-dichlorophenyl phosphoramidate in bovine chromaffin cell cultures. TOXICOLOGY AND APPLIED PHARMACOLOGY. 292-292. 2004
- The inhibition of the high sensitive peripheral nerve soluble esterases by mipafox. A new mathematical processing for the kinetics of inhibition of esterases by organophosphorus compounds. TOXICOLOGY LETTERS. 171-181. 2004
- Cinética de inhibición por mipafox y actividad NTE en cultivos primarios de células cromafines. REVISTA DE TOXICOLOGIA. 131-131. 2003
- Cinética de inhibición por mipafox y actividad NTE en cultivos primarios de células cromafines. REVISTA DE TOXICOLOGIA. 131-131. 2003
- Distribution of serum paraoxon hydrolysing activity in large population using routine automized method in clinical laboratory. JOURNAL OF ANALYTICAL TOXICOLOGY. 290-293. 2003
- Estudio de carboxilesterasas en médula adrenal y cultivo primario de células cromafines de animales de abasto. REVISTA DE TOXICOLOGIA. 132-132. 2003
- Estudio de carboxilesterasas en médula adrenal y cultivo primario de células cromafines de animales de abasto. REVISTA DE TOXICOLOGIA. 132-132. 2003
- Estudio de supervivencia en pacientes adictos a opioides.. REVISTA DE TOXICOLOGIA. 124-124. 2003
- Evaluation of safety of two natural antioxidants extracts on chromaffin cells protection. TOXICOLOGY LETTERS. 57-57. 2003
- Hidrólisis del carbamato carbaryl por albúmina de suero de conejo. REVISTA DE TOXICOLOGIA. 113-113. 2003
- Hidrólisis del carbamato carbaryl por albúmina de suero de conejo. REVISTA DE TOXICOLOGIA. 133-133. 2003
- Neuropathy target esterase activity reactivation in chromaffin cell cultures treated with mipafox. TOXICOLOGY LETTERS. 49-49. 2003
- Neuropathy target esterase activity reactivation in chromaffin cell cultures treated with mipafox. TOXICOLOGY LETTERS. 49-49. 2003
- Prevalencia de infecciones por VIH y VHC: análisis de factores protectores relacionados con el tratamiento de mantenimiento con metadona.. REVISTA DE TOXICOLOGIA. 121-121. 2003
- Properties of phenyl valerate esterase activities from chicken serum are comparable with soluble esterases of peripheral nerves in relation with organophosphorus compounds inhibition.. TOXICOLOGY LETTERS. 1-10. 2003
- Enzymes involved in the detoxification of organophosphorus, carbamate and pyrethroid insecticides through hydrolysis. TOXICOLOGY LETTERS. 215-228. 2002
- Importancia de la hidrólisis estereoespecífica en la evaluación de riesgos de insecticidas fosforamidatos. REVISTA DE TOXICOLOGIA. 61-68. 2002
- Monitoring plasma levels of R-methdone and opiate with drawan symtoms and signs. TOXICOLOGY LETTERS. 2002
- Rabbit serum albumin hydrolyzes the carbamate carbaryl.. CHEMICAL RESEARCH IN TOXICOLOGY. 520-526. 2002
- Actividad hidrolizante de paraoxón y su distribución en 2891 muestras de suero humano.. REVISTA DE TOXICOLOGIA. 180-180. 2001
- Carboxilesterasas de Daphnia Magna como biomarcador de exposición a insecticidas organofosforados.. REVISTA DE TOXICOLOGIA. 181-181. 2001
- Determinación enantioselectiva de metadona, su metabolito principal, fármacos y drogas de abuso en muestras biológicas. ADICCIONES. 23-23. 2001
- Fosfotriesterasas en la evaluación de riesgos de insecticidas organofosforados. REVISTA DE TOXICOLOGIA. 181-182. 2001
- Inhibición de actividad carboxilesterasa por mipafox en fracciones soluble y particulada de médula adrenal bovina.. REVISTA DE TOXICOLOGIA. 182-182. 2001
- Monitorización de niveles R- y S-metadona y su metabolito principal en plasma y orina de pacientes en tratamiento de mantenimiento con metadona. REVISTA DE TOXICOLOGIA. 141-142. 2001
- Consumo legal de metadona en población drogodependiente de la Provincia de Alicante. REVISTA DE TOXICOLOGIA. 115-119. 2000
- Consumo legal de metadona en población drogodependiente de la provincia de Alicante. REVISTA DE TOXICOLOGIA. 115-119. 2000
- High and permanent inhibition of pheripheral nerve soluble esterases by mipafox and S9B, a selective NTE inhibitor, suggest their potential role as neuropathy targets.. Neurotoxicology. 635-635. 2000
- Hydrolisis of hexyl dichlorophenylphosphoramidate in hens, rat and rabbit. Neurotoxicology. 636-636. 2000
- Dichlorophenyl phosphoramidates as substrates for avian and mammalian liver phosphotriesterases: activity levels, calcium dependence and stereospecificity. CHEMICO-BIOLOGICAL INTERACTIONS. 257-262. 1999
- EDTA-Resistant and Sensitive Phosphotriesterase Activities Associated with Albumin and Lipoproteins in Rabbit Serum. DRUG METABOLISM AND DISPOSITION. 53-59. 1999
- Hidrólisis estereoespecífica del O-hexil O-2,5-diclorofenil fosforamidato (HDCP) en gallina,rata y conejo. REVISTA DE TOXICOLOGIA. 150-151. 1999
- Peripheral nerve soluble esterases are spontaneously reactivated after inhibition by some OP compounds: Implications for a new definition of Neuropathy Target Esterase. CHEMICO-BIOLOGICAL INTERACTIONS. 541-550. 1999
- Peripheral nerve soluble esterases are spontaneously reactivated after inhibition by some op compounds: implications for a new definition of NTE. CHEMICO-BIOLOGICAL INTERACTIONS. 541-550. 1999
- Stereospecific hydrolisis of a phosphoramidate related to methamidophos in hen, rat and rabbit. TOXICOLOGY LETTERS. 59-59. 1999
- The concentration of tissue is an important factor in stereospecific enzymatic activity in ¿in vitro¿ assays. TOXICOLOGY IN VITRO. 689-692. 1999
- The role of phosphotriesterases in the detoxication of organophosphorus compounds. CRITICAL REVIEWS IN TOXICOLOGY. 21-57. 1999
-
book
- casos prácticos de evaluación de riesgos toxicologicos y ecotoxicologicos. EDITORIAL ELECTRONICA DE LA UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE. 2018
- TÉCNICAS ANALÍTICAS DE CONTAMINANTES QUÍMICOS. Aplicaciones toxicológicas, medioambientales y alimentarias.. Díaz de Santos. 2004
- Técnicas Analíticas Ambientales. UNIVERSIDAD MIGUEL HERNÁNDEZ. 2003
-
chapter
- Toxicokinetics and toxicodynamics of DFP. Handbook of Toxicology of Chemical Warfare Agents Third Edition. 921-944. 2020
- Biomarkers for Testing Toxicity and Monitoring Exposure to Xenobiotics. Biomarkers in Toxicology. 1165-1174. 2019
- Tendencias en Toxicología Celular y Molecular. EXPERTO EN TOXICOLOGÍA. 1-43. 2018
- OECD Guidelines for In Vivo Testing of Reproductive Toxicity. Reproductive and Developmental Toxicity. 163-178. 2017
- Validated and Nonvalidated Mechanism- Based Methods for Testing Developmental Toxicity. Reproductive and Developmental Toxicity. 193-209. 2017
- Air Quality of Textile and Related Industries. Comprehensive Analytical Chemistry (Volume 73): The Quality of Air. 785-800. 2016
- Toxicokinetics and Toxicodinamics of DFP. Handbook of Chemical Warfare Agents, 2nd edition. 857-874. 2015
- ACROLEIN. Encyclopedia of Toxicology. 63-68. 2014
- Biomarkers in biomonitoring of xenobiotics. BIOMARKERS IN TOXICOLOGY. 965-973. 2014
- Carbon Tetrachloride. Encyclopedia of Toxicology. 687-690. 2014
- Chloroform. Encyclopedia of Toxicology. 885-890. 2014
- ETHYL ACETATE. Encyclopedia of Toxicology. 506-510. 2014
- Lubricating Oils. Encyclopedia of Toxicology. 670-676. 2014
- Merphos. Encyclopedia of Toxicology. 217-220. 2014
- Petroleum Distillates. Encyclopedia of Toxicology. 828-833. 2014
- Biomarkers in biomonitoring of xenobiotics. BIOMARKERS IN TOXICOLOGY. 965-973. 2013
- Embryonic Stem Cells in Toxicological Studies. Embryonic Stem Cells - Basic Biology to Bioengineering. 213-230. 2011
- Mechanism-based models in reproductive and developmental toxicology. In: Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology. 135-146. 2011
- OECD guidelines and validated methods for in vivo testing of reproductive toxicity. Reproductive and Developmental Toxicology. 123-133. 2011
- DETOXICATION OF ANTICHOLINESTERASE PESTICIDES. Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology. 121-133. 2010
- Técnicas de cocción y riesgos tóxicos asociados a procesos culinarios. NUTRICION, EDAD Y VITALIDAD. 403-432. 2009
- Tendencias en Toxicología molecular y celular. Toxicología de Postgrado. 1-30. 2003
- Mecanismos de Toxicidad. Toxicología de Postgrado.. 2002
- Evaluación efecto neurotóxico.. Evaluacion Toxicológica de los Plaguicidas y la Sanidad Ambiental.. 73-88. 2000
- Applied Toxicology: Approaches through basic science. Archives of Toxicology. 347-355. 1998
- Evaluation of neurotoxicity: an example of new approaches needed in risk assesment. Regulatory for chemical dafety in Europe: Analysis, comment and criticism. 1998
-
congress communication
- EFFECTS OF TITANIUM DIOXIDE NANOPARTICLES ON T98G HUMAN GLIOBLASTOMA CELLS 2019
- Environmental factors related with chronic kidney disease of unknown origin (CKDu) of Centro America: relationship of 28 element profile concentrations in drinking water with the prevalence in communities of Nicaragua. 120-120. 2019
- Phenyl valerate esterase activity of human acetylcholinesterase. 216-217. 2019
- Phenyl valerateesterase activity of human acetylcholinesterase 2019
- Borderline between catalytic and non-catalytic bio scavengers: the example of albumin and reversible B-esterases. 39-39. 2018
- Cytotoxicity of metallic nanoparticles on T98G human glioblastoma cells 2018
- Interactions of cholinesterase and phenylvalerate activities on chicken brain membrane fraction regarding organophosphorus neurotoxicity 2018
- Phenyl valerate esterase activity of human cholinesterases. 18-18. 2018
- Are OP developmental toxicants? The example of chlorpyrifos.. 41-41. 2016
- Dianas múltiples de toxicidad a compuestos organofosforados: Relación entre actividad fenilvaleratoesterasa sensible a compuestos organofosforados y colinesterasas 2016
- Embriotoxicidad predicha usando la expresión génica como biomarcador de alteraciones en la diferenciación después de solo 5 días de exposición en células madre embrionarias de ratón In Vitro 2016
- From simple in vitro test to complex models: the example of developmental toxicity of organophosphorus compounds 2016
- Multiple targets of organophosphorus compounds toxicity: relationship among organophosphorus-sensitive phenyl valerate activity and cholinesterases. 242-242. 2016
- NTE Protein and Encoding Gene in Neurodevelopment and Neurodevelopmental Toxicity. 532-532. 2016
- A fraction of the organophosphorus-sensitive phenylvalerate esterase activity shows acetylcholine hydrolyzing activity in soluble fraction of chicken brain. 458-458. 2015
- Butyrylcholinesterase identified as a phenyl valerate esterase activity highly sensitive to mipafox in chicken brain 2015
- Cholinesterase assay by an efficient fixed time endpoint method. 2015
- Discrimination with irreversible inhibitors (mipafox, paraoxon, PMSF and iso-OMPA) of enzimatic components in acetylthiocholine-hydrolyzing activity 2015
- Effects of mipafox, paraoxon, chlorpyrifos and its metabolite chlorpyrifos-oxon on D3 mouse embryonic stem cell differentiation 2015
- Human neuroblastoma SH-SY5Y as potential model for studying the role of esterases in human central nervous system 2015
- Interactions of acetylthiocholine in chicken brain carboxylesterase activities of brain 2015
- LC-MS/MS Proteomics Analysis Identifies Butyrylcholinesterase As a Protein with Phenylvalerate Esterase Activity. 458-458. 2015
- No aging no reactivation of human acetyl cholinesterase inhibited by mipafox demostrate by mass spectrometry and QMMM approaches. 2015
- Phenylvalerate esterase activity and inhibition of human butyrylcholinesterase: kinetic and molecular modeling demonstration 2015
- Roles of NTE protein and encoding gene in neurodevelopment and neurodevelopmental toxicity 2015
- mRNAs as tools for in vitro assessment of developmental toxicity of chlorpyrifos. 375-375. 2015
- Determinación de Al, Cd, Ni y Pb en diferentes tipos de ¿golosinas¿. 252-252. 2014
- Human and mouse gene expression pathways of neural embryonic cell differentiation in developmental toxicity. 15-15. 2014
- Analysis of the drinking water in 89 grounds in the area of higher prevalence of chronic kidney disease (CKD) of etiology unknown in Nicaragua 2013
- Análisis de las aguas de consumo humando en 89 pozos de la zona de mayor prevalencia de Enfermedad Renal Crónica (ERC) de etiología desconocida en Nicaragua 2013
- Cytotoxic effect of aqueous extracts of saffron floral bio-residues. 1637-1637. 2013
- Esterases interacting with organophosphorus compounds different to cholinesterases and neuropathy target esterase in nerve tissues 2013
- Interactions of a Promoter/Potentiator of Neuropathy and Esterases of Membrane and Soluble Fractions of Brain.. 303-303. 2013
- Predicting Embryotoxicity Using Gene Expression as Biomarker of Alterations in Differentiation after only 5 Days of Exposure in mouse In Vitro Embryonic Stem Cells 2013
- Short new in vitro developmental toxicity assays on embryonic stem cells based on gene biomarker of differentiation. Example of application to the neurotoxicant chlorpyrifos 2013
- Theoretical kinetic aspects of enzymes reacting with OPs. 164-165. 2013
- Chlorpyrifos and metabolites alter differentiation at non-cytotoxic concentrations. 64-64. 2012
- Effect of neuropathy target esterase inhibition and silencing on NT2 differentiation.. 64-65. 2012
- Genic expression changes in mouse embryonic stem cells after 12-hour exposure to chlorpyrifos and its metabolite 2012
- KINETIC INTERACTION OF PMSF (A NEUROPATHY PROMOTER) WITH MEMBRANE-BOUND ESTERASES THAT ARE SENSITIVE OR RESISTANT TO ORGANOPHOSPHORUS INDUCERS OF DELAYED NEUROPATHY. 304-305. 2012
- Kinetic identification of organophosphate-sensitive esterases in brain membrane. 171-171. 2012
- PMSF ALTERS THE INTERACTION OF CHICKEN BRAIN ESTERASES WITH ORGANOPHOSPHOROUS COMPOUNDS 2012
- The absence of Neuropathy Target Esterase (NTE) expression alters neurodevelopment: evidences of a biological basic function of NTE 2012
- Changes in the gene expression of mouse embryonic stem cells after 12 hours exposure to chemicals. I.e.: chlorpyrifos and its metabolite 2011
- Gene silencing as a tool to study the role of Neuropathic Target Esterase (NTE) in the process of cell differentiation into neuron-like phenotypes 2011
- KINETIC CARACTERIZATION OF ORGANOPHOSPHORUS COMPOUNDS IN ESTERASES OF BRAIN MEMBRANE . 231-231. 2011
- KINETIC INTERACTION OF SOLUBLE ESTERASES OF BRAIN AND PHENYLMETHYLSULPHONYL FLUORIDE (PMSF), AN INHIBITOR PROTECTING AND POTENTIATING THE ORGANOPHOSPHORUS DELAYED NEUROTOXICITY.. 450-451. 2011
- Neuropathy Target Esterase (NTE) codifying gen as bioindicator of embryotoxicity in in vitro test. 209-209. 2011
- USE OF BIOMARKERS OF DIFFERENTIATION FOR IMPROVING THE EMBRYONIC STEM CELL TEST 2011
- Improved procedure for biomonitoring 28 elements in human hair: sample collection, treatment and analytical method by ICP-MS. 40-41. 2010
- Inhibition and spontaneous reactivation of esterases by. 320-321. 2010
- KINETIC OF THE ESTEREOSPECIFIC INTERACTION OF A MODEL CHIRAL PHOSPHORAMIDATE WITH ESTERASES IN PERIPHERAL NERVE SOLUBLE FRACTION.. 266-266. 2010
- Neuropathy Target Esterase (NTE) as potential biomarker of embryotoxicity during early stages of development. 151-151. 2010
- Neuropathy Target Esterase (NTE) might be playing a relevant role during cell differentiation 2010
- Possible improvements to embryonic stem cell test (EST) using molecular markers of cell differentiation. 155-155. 2010
- Silencing of Neuropathy Target Esterase (NTE) causes changes in gene expression during the early stages of differentiation. 98-98. 2010
- Silencing of Neuropathy Target Esterase (NTE) modifies gene expression during first stages of differentiation. 190-190. 2010
- The real role of paraoxonase and serum albumins in the detoxication of paraoxon and other organophosphorus pesticides 2010
- Caracterización parcial de la esterasa diana de neuropatía en células madre embrionarias de ratón 2009
- INHIBITION WITH SPONTANEOUS REACTIVATION AND "ONGOING INHIBITION" EFFECT OF ESTERASES BY THE BIOTINYLATED ORGANOPHOSPHORUS COMPOUNDS: S9B AS A MODEL 2009
- Improved analyticalmethod for monitoring exposure to volatile compounds for occupational risk prevention 2009
- Kinetic of inhibition of esterases by non-stable compounds: PMSF as a model. 213-213. 2009
- Mouse embryonic stem cells for testing the role of neuropathy target esterase in embryogenesis 2009
- Neuropathy Target Esterase in mouse embryonic stem cells 2009
- Role of human serum albumin in the detoxication of organophosphorus insecticides. 246-246. 2009
- Serum albumin, and not lipoprotein paraoxonase, is the responsible of the paraoxon detoxication at in vivo toxicologically relevant conditions 2009
- Serum albumins and detoxication of anticholinesterase agents 2009
- Human serum albumin hydrolyzes the organophosphorus insecticides paraoxon, diazoxon, chlorpyrifos-oxon and O-hexyl O-2,5-dichlorophenyl phosphoramidate. 29-29. 2008
- INHIBITION WITH SPONTANEOUS REACTIVATION OF ESTERASES BY ORGANOPHOSPHORUS COMPOUNDS: PARAOXON AS A MODEL.. 90-90. 2008
- Inhibition with spontaneous reactivation of esterases by organophosphorus compounds: Paraoxon as a model. 91-91. 2008
- Albúmina de suero humano hidroliza paraoxon ¿in vitro¿ 2007
- Albúmina es la proteína responsable de la destoxicación de carbaryl en suero in vivo 2007
- Characterization of the Paraoxonase-like Activity Associated to Human Serum Albumin 2007
- Inhibición por mipafox de la actividad fenilvalerato esterasa en fracción particulada de medula adrenal bovina durante el tiempo de reacción enzima sustrato 2007
- Serum albumin plays a critical role in the detoxication of the carbamate carbaryl 2007
- Plasmidic vector of human neuropathy target esterase in primary cultures of bovine chromaffin cells 2006
- Preliminar characterization of carboxylesterase activities found in plasma of wild birds 2006
- Role of serum albumins in the detoxication of the carbamate carbaryl 2006
- Análisis cinético de la interacción con paraoxon de las carboxilesterasas solubles de nervio periférico: evidencia de su rápida reactivación espontánea in vivo. 124-125. 2005
- Análisis cinético de la interacción con paraoxon de las carboxilesterasas solubles de nervio periférico: evidencia de su rápida reactivación espontánea in vivo 2005
- Análisis de la citotoxicidad de compuestos organofosforados sobre cultivos primarios de células cromafines bovinas. 2005
- Caracterización parcial de actividades carboxilesterasa de plasma de aves silvestres. 2005
- Design of a chromatografic method for studying the effect of xenobiotics on the secretion of neurotransmitters 2005
- Estudio comparativo de citotoxicidad aguda inducida por organofosforados en células cromafines bovinas en cultivo 2005
- Influencia del consumo de sustancias en el metabolismo de metadona: Inducción de CYP2B6 2005
- Monitorización terapéutica de R-metadona: Interacción farmacológica entre nevirapina, efavirenz y metadona 2005
- POSIBLE PAPEL DE LAS CARBOXILESTERASAS DE SUERO COMO BIOMARCADORES DE LA INHIBICIÓN IN VIVO DE LAS CARBOXILESTERASAS SOLUBLES DE NERVIO PERIFÉRICO POR COMPUESTOS PROMOTORES DE AXONOPATÍAS. 124-124. 2005
- Posible papel de las carboxilesterasas de suero como biomarcadores de la inhibición in vivo de las carboxilesterasas solubles de nervio periférico por compuestos promotores de axonopatías 2005
- Efectos de los organofosforados sobre la secreción de neurotransmisores en cultivos primarios de células cromafines 2004
- Efectos de organofosforados sobre la secreción de neurotransmisores en cultivos primarios de células cromafines 2004
- Human serum albumin hydrolyses the carbamate carbaryl 2004
- Mipafox treatment increases the 5-HT secretion in bovine chromaffin cells cultures 2004
- Spontaneous recuperation of neuropathy target esterase activity after treatment with mipafox and O-hexyl O-2,5-dichlorophenyl phosphoramidate in bovine chromaffin cell cultures 2004
- Spontaneous recuperation of neuropathy target esterase activity after treatment with mipafox and O-hexyl O-2,5-dichlorophenyl phosphoramidate in bovine chromaffin cell cultures 2004
- Cinética de inhibición por mipafox y actividad NTE en cultivos primarios de células cromafines 2003
- El cultivo de células cromafines recupera la actividad de la esterasa diana de neuropatía después de su inhibición con mipafox 2003
- Estudio de carboxilesterasas en médula adrenal y cultivo primario de células cromafines de animales de abasto 2003
- Estudio de supervivencia en pacientes adictos a opioides. 2003
- Hidrólisis del carbamato carbaryl por albúmina de suero de conejo 2003
- La medida de neurotransmisores por LC-MS es una buena alternativa para la medida de neurotransmisores : el ejemplo de la secreción de células cromafines en cultivo 2003
- Neuropathy target esterase activity reactivation in chromaffin cell cultures treated with mipafox 2003
- Neuropathy target esterase activity reactivation in chromaffin cell cultures treated with mipafox 2003
- Neuropathy target esterase activity recuperation after treatment with organophosphorus compounds in chromaffin cell cultures 2003
- Prevalencia de infecciones por VIH y VHC: análisis de factores protectores relacionados con el tratamiento de mantenimiento con metadona. 2003
- RESPUESTA IN VIVO E IN VITRO DE LAS CARBOXILESTERASAS SOLUBLES DE NERVIO PERIFÉRICO A COMPUESTOSINDUCTORES Y PROMOTORES DE NEUROPATÍA. 130-130. 2003
- Recuperación de la esterasa diana de neuropatía en cultivo de células cromafines bovinas después de la inhibición con mipafox 2003
- Further characteritation of carboxylesterases in chromaffin cells as potential model to study organophosphorus neurotoxicity. 2002
- IN VIVO PROTECTION FROM DFP INHIBITION OF PERIPHERAL NERVE SOLUBLE ESTERASES BY PARAOXON.. 157-157. 2002
- Monitoring plasma levels of R-methadone and opiate withdrawan symtoms and signs 2002
- Carboxilesterasas de Daphnia magna como biomarcadores de exposición a insecticidas organofosforados 2001
- Carboxylesterases from Daphnia magna as biomarker of exposition to organophosphorus compounds 2001
- Fosfotriesterasas en la evaluación de riesgos de insecticidas organofosforados 2001
- INHIBICION IN VIVO DE FENILVALERATO ESTERASAS SOLUBLES DE NERVIO PERIFERICO POR INDUCTORES Y PROMOTORES DE NEUROPATIA. 130-130. 2001
- Inhibición de la actividad carboxilesterasa por mipafox en fracciones soluble y particulada de médula adrenal bovina 2001
- Monitorización de niveles de R- y S-metadona y su metabolito principal en plasma y orina de pacientes en tratamiento de mantenimiento con metadona 2001
- Role of phosphotriesterases in the risk assessment of organophosphorus pesticides 2001
- A NEW MATHEMATICAL PROCESSING FOR THE KINETICS OF INHIBITION OF ESTERASES BY ORGANOPHOSPHORUS COMPOUNDS: THE INHIBITION OF PERIPHERAL NERVE SOLUBLE ESTERASES BY MIPAFOX AS A MODEL. 73-73. 2000
- Carboxylesterases interacting with organophosphorus pesticides in the ecotoxicity test model Daphnia magna 2000
- PHENYL VALERATE ESTERASE ACTIVITIES FROM CHICKEN SERUM SHOWS AN EXTREMELY HIGH SENSITIVITY TO ORGANOPHOSPHORUS COMPOUNDS. 56-56. 2000
- SERUM PHENYL VALERATE ESTERASE ACTIVITIES FROM CHICKEN FOR PRESCREENING ORGANOPHOSPHORUS COMPOUNDS 2000
- Estudio de las carboxilesterasas en daphnia magna. 170-170. 1999
- HIDROLISIS ESTEREOESPECIFICA DEL O-HEXIL- O-2,5-DICLOROFENIL FOSFORAMIDATO (HDCP) EN GALLINA, RATA Y CONEJO.. 150-151. 1999
- Hidrólisis estereoespecífica del O-Hexil O-2,5-Diclorofenil fosforamidato (HDCP) en gallina, rata y conejo 1999
- Hight and permanent inhibition of peripheral nerve soluble esterases by mipafox and S9B, a selective nte inhibitor, suggest their potential role as neuropathy targets.. 21-21. 1999
- Hydrolisis of hexyl dichlorophenyl phosphoramidate in hen, rat and rabbit 1999
- Hydrolysis of hexyl dichlorophenyl phosphoramidate in hen, rat and rabbit. 21-21. 1999
- Stereospecific hydrolisis of a phosphoramidate related to methamidophos in hen, rat and rabbit 1999
- Stereospecific hydrolysis of a phosphoramidate related to methamidophos in hen, rat and rabbit. 109-109. 1999
- The role of esterases in the biodegradation of organophosphorus compounds 1999
- Una fuerte y permanente inhibicion de esterasas solubles de nervio periferico por mipafox y S9B, un inhibidor selectivo de nte, sugiere un potencial papel como dianas de neuropatias. 153-153. 1999
- HIGH RATE OF ESPONTANEUS REACTIVATION OF ESTERASES IN CHICKEN PERIPHERAL NERVE AND LIVER AFTER INHIBITION BY SOME ORGANOPHOSPHORUS COMPOUNDS.. 146-146. 1998
-
patent
-
proceedings