Publicaciones en VIVO

Mapa de la ciencia

Red de Coinvestigador

BARCO GUERRERO, ANGEL

Person (Active)

Positions

RESPONSABLE DE UNIDAD A EFECTOS DE FIRMA DE COMISIONES DE SERVICIO, Instituto de Neurociencias 2021 -
PROFESOR DE INVESTIGACIÓN CSIC, Instituto de Neurociencias 2016 -
INVESTIGADOR CIENTIFICO CSIC, Instituto de Neurociencias 2010 - 2016
CIENTIFICO TITULAR CSIC, Instituto de Neurociencias 2008 - 2010

Publications
Research
Teaching
Service
Contact
Otro
Ver todos

supported publications or other works

selected publications

academic article
- Kdm1a safeguards the topological boundaries of PRC2-repressed genes and prevents aging-related euchromatinization in neurons. NATURE COMMUNICATIONS. 1781. 2024
- Keep calm and carry H3K27me1 off. NEURON. 2829-2832. 2024
- Extra centrosomes induce PIDD1-mediated inflammation and immunosurveillance. EMBO JOURNAL. 113510. 2023
- CBP and p300 Jointly Maintain Neural Progenitor Viability but Play Unique Roles in the Differentiation of Neural Lineages. CELLS. 1-18. 2022
- Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly . ELIFE. 71575. 2021
- Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis. CELL REPORTS. 109229. 2021
- Transcriptome and epigenome analysis of engram cells: Next-generation sequencing technologies in memory research . NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 865-875. 2021
- A Zic2-regulated switch in a noncanonical Wnt/ßcatenin pathway is essential for the formation of bilateral circuits. SCIENCE ADVANCES. 1-13. 2020
- KAT3-dependent acetyl of cell-specific genes maintains neuronal identity in the adult mouse brain. NATURE COMMUNICATIONS. 1-18. 2020
- Transcriptome analysis of iPSC-derived neurons from Rubinstein-Taybi patients reveals deficits in neuronal differentiation. MOLECULAR NEUROBIOLOGY. 3685-3701. 2020
- CBP and SRF co-regulate dendritic growth and synaptic maturation. CELL DEATH AND DIFFERENTIATION. 2208-2222. 2019
- CBP/p300 in brain development and plasticity: Disentangling the KAT¿s cradle. CURRENT OPINION IN NEUROBIOLOGY. 1-8. 2019
- Environmental enrichment induces axon regeneration and recovery after peripheral and spinal injuries via activity mediated CBP-dependent histone acetylation: a druggable pathway. SCIENCE TRANSLATIONAL MEDICINE. 487. 2019
- Immediate and deferred epigenomic signatures of in vivo neuronal activation in mouse hippocampus.. NATURE NEUROSCIENCE. 1718-1730. 2019
- The Contribution of Spurious Transcription to Intellectual Disability Disorders. JOURNAL OF MEDICAL GENETICS. 491-498. 2019
- Editorial on the Special Issue: Molecules and Cognition.. NEUROSCIENCE. 1-3. 2018
- Impact of environmental conditions and chemicals on the neuronal epigenome. CURRENT OPINION IN CHEMICAL BIOLOGY. 157-165. 2018
- The Epigenetic Factor CBP Is Required for the Differentiation and Function of Medial Ganglionic Eminence-Derived Interneurons. MOLECULAR NEUROBIOLOGY. 4440-4454. 2018
- arly alteration of epigenetic-related transcription in Huntington¿s disease mouse models. SCIENTIFIC REPORTS. 9925-9930. 2018
- CREB regulates distinct activity-dependent transcriptional programs in astrocytes and neurons. SCIENTIFIC REPORTS. 6390. 2017
- Epigenetic etiology of intellectual disability. JOURNAL OF NEUROSCIENCE. 10773-10782. 2017
- Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects.. ELIFE. 1-26. 2017
- Loss of Kdm5c Causes Spurious Transcription and Prevents the Fine-Tuning of Activity-Regulated Enhancers in Neurons.. CELL REPORTS. 47-59. 2017
- Skill learning modulates RNA Pol II poising at immediate early genes in the adult striatum. ENEURO. 2. 2017
- Blocking miRNA biogenesis in adult forebrain neurons enhances seizure susceptibility, fear memory and food intake by increasing neuronal responsiveness. CEREBRAL CORTEX. 1619-1633. 2016
- Nuclear Organization and 3D Chromatin Architecture in Cognition and Neuropsychiatric Disorders. MOLECULAR BRAIN. 83. 2016
- Role of Dicer and the miRNA system in neuronal plasticity and brain function. NEUROBIOLOGY OF LEARNING AND MEMORY. 3-12. 2016
- Specific promoter deacetylation of histone H3 is conserved across mouse models of Huntington's disease in the absence of bulk changes. NEUROBIOLOGY OF DISEASE. 190-201. 2016
- Targeted activation of CREB in reactive astrocytes is neuroprotective in focal acute cortical injury. GLIA. 853-874. 2016
- Blocking miRNA Biogenesis in Adult Forebrain Neurons Enhances Seizure Susceptibility, Fear Memory, and Food Intake by Increasing Neuronal Responsiveness.. CEREBRAL CORTEX. 1619-1633. 2015
- Brain size regulations by cbp haploinsufficiency evaluated by in vivo MRI based volumetry. SCIENTIFIC REPORTS. 16256. 2015
- Editorial MCCS Special Issue. NEUROBIOLOGY OF LEARNING AND MEMORY. 1-2. 2015
- Fine-tuned SRF activity controls asymmetrical neuronal outgrowth: implications for cortical migration, neural tissue lamination and circuit assembly. SCIENTIFIC REPORTS. 17470-17484. 2015
- Can changes in histone acetylation contribute to memory formation?. TRENDS IN GENETICS. 1-11. 2014
- Histone acetylation and CREB binding protein are required for neuronal resistance against ischemic injury. PLOS ONE. 1-13. 2014
- Loss of neuronal 3D chromatin organization causes transcriptional and behavioural deficits related to serotonergic dysfunction. NATURE COMMUNICATIONS. 1-14. 2014
- Loss of neuronal 3D chromatin organization causes transcriptional and behavioural deficits related to serotonergic dysfunction.. NATURE COMMUNICATIONS. 4450-4464. 2014
- Neuroepigenetic disorders: Progress, promises and challenges (comentario). NEUROPHARMACOLOGY. 1-2. 2014
- The Neuronal Activity-Driven Transcriptome. MOLECULAR NEUROBIOLOGY. 32914-32925. 2014
- cAMP Responsive Element Binding Protein (CREB) and cAMP Co-regulate Activator Protein 1 (AP1)-Dependent Regeneration-Associated Gene Expression and Neurite Growth. JOURNAL OF BIOLOGICAL CHEMISTRY. 1-13. 2014
- Genomic landscape of transcriptional and epigenetic dysregulation in early-onset polyglutamine disease. JOURNAL OF NEUROSCIENCE. 10471-10482. 2013
- Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition. NUCLEIC ACIDS RESEARCH. 8072-8084. 2013
- Histone H3 methylation in cognition and intellectual disability disorders. LEARNING & MEMORY. 570-579. 2013
- Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders. CURRENT PHARMACEUTICAL DESIGN. 5051-5064. 2013
- Enhanced cAMP Response Element-Binding Protein Activity Increases Neuronal Excitability, Hippocampal Long-Term Potentiation, and Classical Eyeblink Conditioning in Alert Behaving Mice. JOURNAL OF NEUROSCIENCE. 17431-17441. 2012
- Hippocampal gene profiling: toward a systems biology of the hippocampus. HIPPOCAMPUS. 929-941. 2012
- Ablation of CBP in forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation, but does not affect cell viability. JOURNAL OF NEUROSCIENCE. 1652-1663. 2011
- CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement. EMBO JOURNAL. 4287-4298. 2011
- CREB is as a primary hub of activity-driven neuronal gene expression. JOURNAL OF NEUROSCIENCE. 1-1. 2011
- Histone acetylation deficits in lymphoblastoid cell lines from patients with Rubinstein-Taybi syndrome. JOURNAL OF MEDICAL GENETICS. 66-74. 2011
- CREB's control of intrinsic and synaptic plasticity: Implications for CREB-dependent memory models. TRENDS IN NEUROSCIENCES. 230-240. 2010
- La materia de los recuerdos: circuitos neuronales y cascadas moleculares. MENTE Y CEREBRO. 24-33. 2010
- Ultrastructural and transcriptional profiling of neuropathological misregulation of CREB function. CELL DEATH AND DIFFERENTIATION. 1636-1644. 2010
- Chronic enhancement of CREB activity in the hippocampus interferes with the retrieval of spatial information. LEARNING & MEMORY. 198-209. 2009
- Enhanced CREB-dependent gene expression increases the excitability of neurons in the basal amygdala and primes the consolidation of contextual and cued fear memory. LEARNING & MEMORY. 193-197. 2009
- Germ line expression of H-RasG12V causes neurological deficits associated to Costello syndrome. GENES BRAIN AND BEHAVIOR. 60-71. 2009
- Inhibition of cAMP response element binding protein reduces neuronal excitability and plasticity, and triggers neurodegeneration. CEREBRAL CORTEX. 2535-2547. 2009
- Inhibition of cAMP responsive element binding protein in striatal neurons enhances approach and avoidance responses towards morphine- and morphine withdrawal- related cues. FRONTIERS IN BEHAVIORAL NEUROSCIENCE. 2009
- Selective boosting of transcriptional and behavioral responses to drugs of abuse by histone deacetylase inhibition. NEUROPSYCHOPHARMACOLOGY. 2642-2654. 2009
- Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology. NEUROBIOLOGY OF DISEASE. 186-194. 2009
- Synapse-specific stabilization of plasticity processes: the synaptic tagging and capture hypothesis revisited 10 years later.. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 831-851. 2008
- CREB-mediated gene expression increases the intinsic excitability of CA1 pyramidal neurons. JOURNAL OF NEUROSCIENCE. 13909-13918. 2007
- The Rubinstein-Taybi syndrome: Modeling mental impairment in the mouse. GENES BRAIN AND BEHAVIOR. 32-39. 2007
- A MEETING TO REMEMBER: MEETING ON MEMORY AND RELATED DISORDERS. EMBO REPORTS. 768-773. 2006
- Capture of L-LTP within and across the apical and basilar dendritic compartments of CA1 pyramidal neurons: synaptic tagging is restricted to specific dendritic compartments. JOURNAL OF NEUROSCIENCE. 256-264. 2006
- Common molecular mechanisms in explicit and implicit memory. JOURNAL OF NEUROCHEMISTRY. 1520-1533. 2006
- CREB binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME. 19186-19191. 2005
- Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for both the maintenance of LTP and for its synaptic capture. . NEURON. 123-137. 2005
- A semi-persistent adult ocular dominance plasticity in visual cortex is stabilized by activated CREB. LEARNING & MEMORY. 738-747. 2004
- Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo. . NEURON. 609-621. 2004
- Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. NEURON. 947-959. 2004
- Individual expression of poliovirus 2APRO induces caspase-3 activation and PARP cleavage in HeLa cells. . VIRUS RESEARCH. 39-49. 2004
- Transient expansion of synaptically connected dendritic spines upon induction of hippocampal long-term potentiation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES. 16665-16670. 2004
- CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects. EXPERT OPINION ON THERAPEUTIC PATENTS. 39-49. 2003
- Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture. CELL. 689-703. 2002
- Viroporin-mediated membrane permeabilization: pore formation by non-structural poliovirus 2B protein. JOURNAL OF BIOLOGICAL CHEMISTRY. 40434-40441. 2002
- A stable HeLa cell line that inducibly expresses poliovirus 2Apro: effects on cellular and viral gene expression. JOURNAL OF VIROLOGY. 2383-2392. 2000
- Poliovirus Protease 3C(pro) Kills Cells by Apoptosis. VIROLOGY. 352-360. 2000
- Genetic selection of poliovirus 2Apro-binding peptides. JOURNAL OF VIROLOGY. 814-818. 1999
- Co-expression of human eIF-4G and poliovirus 2Apro in Saccharomyces cereviseae: Effects on gene expression. JOURNAL OF GENERAL VIROLOGY. 2651-2660. 1998
- Identification of regions involved in cytotoxicity in poliovirus 2BC protein. JOURNAL OF VIROLOGY. 3560-3570. 1998
- Mutational analysis of poliovirus 2Apro distinct inhibitory functions of 2Apro on translation and transcription. JOURNAL OF BIOLOGICAL CHEMISTRY. 27960-27967. 1998
- The yeast Saccharomyces cerevisiae as a genetic system for obtaining variants of poliovirus protease 2A. JOURNAL OF BIOLOGICAL CHEMISTRY. 12683-12691. 1997
- Membrane permeabilization by poliovirus protein 2B and 2BC. JOURNAL OF BIOLOGICAL CHEMISTRY. 23134-23137. 1996
- A human virus protein, poliovirus protein 2BC, induces membrane proliferation and blocks the exocytic pathway in the yeast Saccharomyces cereviseae. EMBO JOURNAL. 3349-3364. 1995
- Cloning and inducible synthesis of poliovirus non-structural proteins in Saccharomyces cerevisiae. GENE. 19-25. 1995
- Poliovirus 2Apro expression inhibits growth of yeast cells. FEBS LETTERS. 4-8. 1995
chapter
- New Genome-Wide Technologies to Study Activity-Regulated Transcription. Transcriptional Regulation by Neuronal Activity: To the Nucleus and Back. 561-591. 2024
- Unveiling Transcriptional and Epigenetic Mechanisms Within Engram Cells: Insights into Memory Formation and Stability. Engrams. 111-129. 2024
- Epigenetic factors in intellectual disability: The Rubinstein¿Taybi syndrome as a paradigm of neurodevelopmental disorder with epigenetic origin. Epigenetics and Neuroplasticity - Evidence and Debate. 139-176. 2014
- Molecular studies of learning and memory in Aplysia and the hippocampus: A comparative analysis of implicit and explicit memory storage. LEARNING AND MEMORY: A COMPREHENSIVE REFERENCE. 11-29. 2008
- CREB-DEPENDENT TRANSCRIPTION AND SYNAPTIC PLASTICITY. TRANSCRIPTIONAL REGULATION BY NEURONAL ACTIVITY. 127-154. 2007
- EL CEREBRO PLASTICO. UNIDAD DIDACTICA VIAJE AL UNIVERSO NEURONAL. 90-111. 2007
- Role of CREB and CBP in brain function. Transcription factors in the nervous system: Development, brain function and disease . 325-375. 2005
- Effects of viral replication on cellular membrane metabolism and function. Molecular Biology of Picornavirus . 337-354. 2002
congress communication

presentations

invited conference
- Epigenetic Etiologia Of Intellectual Disability, Conferencia 2023
- Epigenetic Etiologia Of Intellectual Disability, Conferencia 2023
- Epigenetic Etiologia Of Intellectual Disability, Conferencia 2023
- Epigenetic Etiologia Of Intellectual Disability, Conferencia 2023
- Immediate and deferred epigenomic signature of neuronal activation in hippocampal circuits, Conferencia 2019
- Epigenetic etiology of intellectual disability: Focus on the Rubinstein-Taybi syndrome, Conferencia 2019
- Epigenetic etiology of intellectual disability: Focus on the Rubinstein-Taybi syndrome, Conferencia 2019
- Modeling Rubinstein - Taybi syndrome - Memory, mental retardation and histone acetylation: The epigenetic connection, Conferencia 2009
- Expresión génica y memoria, Conferencia 2009
- Regulation of neuronal plasticity by CREB, Conferencia 2009
- Memory, mental retardation and histone acetylation: the epigenetic connection, Conferencia 2008
- Transcriptional regulation in synaptic plasticity and memory: role of the CREB pathway, Conferencia 2008
- Closing the gap between genes and memory: control of synaptic plasticity and neuronal survival by CREB., Conferencia 2007
- Circuitos moleculares implicados en la memoria, Conferencia 2006
- Survival and synaptic plasticity in CA1 hippocampal neurons depend on normal levels of activity in the CREB pathway, Conferencia 2006
- Gene expression and long-lasting forms of synaptic plasticity and memory., Conferencia 2006
- Transcriptional regulation, long-term potentiation and memory: The CREB binding protein., Conferencia 2005
- Role of the CREB activation pathway in the consolidation of synaptic plasticity and memory processes., Conferencia 2005
- Role of the CREB activation pathway in the consolidation of synaptic plasticity and memory processes, Conferencia 2005
- Chromatin remodeling, LTP and mental retardation: CBP and the CREB pathway., Conferencia 2005
- Regulación transcripcional en la ruta CREB, plasticidad sináptica y memoria, Conferencia 2005