Publicaciones en VIVO

Mapa de la ciencia

Red de Coinvestigador

GARCÍA GUTIERREZ, MARIA SALUD

Person (Active)

Positions

Profesor/a Titular Universidad, Farmacología, Pediatría y Química Orgánica 2019 -
PDI INVESTIGADOR, Instituto de Neurociencias 2022 -
MIEMBRO, Neuropsicofarmacología Traslacional 2015 -
Profesor/a Contratado/a Doctor/a, Farmacología, Pediatría y Química Orgánica 2017 - 2019
Profesor/a Ayudante Doctor/a, Farmacología, Pediatría y Química Orgánica 2012 - 2017
PREDOCTORALES INSTITUTO DE SALUD CARLOS III, Instituto de Neurociencias 2008 - 2010
FPU-MINISTERIO, Instituto de Neurociencias 2007 - 2008
BECARIO/A DE INVESTIGACIÓN (INSTITUTOS), Instituto de Neurociencias 2006 - 2007
GRUPO 2: BECAS A TITULADOS DE GRADO MEDIO Y SUPERIOR, Instituto de Neurociencias 2006 - 2007

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selected publications

academic article
- Adolescent intermittent ethanol exposure decreases perineuronal nets in the hippocampus in a sex dependent manner: Modulation through pharmacological inhibition of RPTPß/¿ . NEUROPHARMACOLOGY. 1-11. 2024
- Understanding the Biological Relationship between Migraine and Depression. BIOMOLECULES. 1-37. 2024
- Alterations of BDNF, mGluR5, Homer1a, p11 and excitatory/inhibitory balance in corticolimbic brain regions of suicide decedents. JOURNAL OF AFFECTIVE DISORDERS. 366-376. 2023
- Cognitive Alterations in Addictive Disorders: A Translational Approach. BIOMEDICINES. 1796-1851. 2023
- Emotional Processing and Maltreatment During Childhood as Factors of Vulnerability to Alcohol Abuse in Young Adults. INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION. 1-21. 2023
- Methods to Identify Cognitive Alterations from Animals to Humans: A Translational Approach. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 7653-7686. 2023
- Molecular Changes Associated with Suicide. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 16726-16759. 2023
- Role of CB2 cannabinoid receptor in the development of food addiction in male mice. NEUROBIOLOGY OF DISEASE. 106034-106048. 2023
- Unveiling behavioral and molecular neuroadaptations related to the antidepressant action of cannabidiol in the unpredictable chronic mild stress model. FRONTIERS IN PHARMACOLOGY. 117164-117166. 2023
- Biomarkers of the Endocannabinoid System in Substance Use Disorders.. BIOMOLECULES. 1-47. 2022
- Immunomodulatory Role of CB2 Receptors in Emotional and Cognitive Disorders. . FRONTIERS IN PSYCHIATRY. 1-15. 2022
- Molecular Alterations of the Endocannabinoid System in Psychiatric Disorders.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 1-66. 2022
- CB2 Receptor Involvement in the Treatment of Substance Use Disorders. BIOMOLECULES. 1-18. 2021
- Differences in Gene Expression of Endogenous Opioid Peptide Precursor, Cannabinoid 1 and 2 Receptors and Interleukin Beta in Peripheral Blood Mononuclear Cells of Patients With Refractory Failed Back Surgery Syndrome Treated With Spinal Cord Stimulation: Markers of Therapeutic Outcomes. NEUROMODULATION. 49-60. 2021
- Editorial: Cannabidiol treatment in neurotherapeutic interventions. FRONTIERS IN PHARMACOLOGY. 1-2. 2021
- Editorial: The Search for Biomarkers in Psychiatry. FRONTIERS IN PSYCHIATRY. 720411-720412. 2021
- Role of cannabidiol in therapeutic intervention for substance use disorders. FRONTIERS IN PHARMACOLOGY. 1-24. 2021
- Therapeutic potential of the cannabinoid receptor 2 in neuropsychiatry. EXPLORATION OF NEUROPROTECTIVE THERAPY . 55-71. 2021
- Association of cannabinoid receptor genes (CNR1 and CNR2) polymorphisms and pani. ANXIETY STRESS AND COPING. 256-265. 2020
- Association of cannabinoid receptor genes (CNR1 and CNR2) polymorphisms and panic disorder. ANXIETY STRESS AND COPING. 2020
- Biomarkers in Psychiatry: Concept, Definition, Types and Relevance to the Clinical Reality. FRONTIERS IN PSYCHIATRY. 1-14. 2020
- Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders. BIOMOLECULES. 1-34. 2020
- Cannabis Use in Pregnant and Breastfeeding Women: Behavioral and Neurobiological Consequences. FRONTIERS IN PSYCHIATRY. 1-15. 2020
- Differences in Gene Expression of Endogenous Opioid Peptide Precursor, Cannabinoid 1 and 2 Receptors and Interleukin Beta in Peripheral Blood Mononuclear Cells of Patients With Refractory Failed Back Surgery Syndrome Treated With Spinal Cord Stimulation: Markers of Therapeutic Outcomes?. NEUROMODULATION. 2020
- Endocannabinoid System Components as Potential Biomarkers in Psychiatry. FRONTIERS IN PSYCHIATRY. 1-30. 2020
- Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment?. FRONTIERS IN PSYCHIATRY. 1-17. 2020
- Cannabidiol does not display drug abuse potential in mice behavior.. ACTA PHARMACOLOGICA SINICA. 358-364. 2019
- Gender differences in the effects of cannabidiol on ethanol binge drinking in mice. ADDICTION BIOLOGY. 1-10. 2019
- Alterations in gene and protein expression of cannabinoid CB2 and GPR55 receptors in the dorsolateral prefrontal cortex of suicide victims. NEUROTHERAPEUTICS. 796-806. 2018
- Cannabidiol does not display drug abuse potential in mice behavior. ACTA PHARMACOLOGICA SINICA. 1-7. 2018
- Cannabidiol reduces ethanol consumption, motivation and relapse in mice. ADDICTION BIOLOGY. 154-164. 2018
- Cannabidiol regulates the expression of hypothalamus-pituitary-adrenal axis-related genes in response to acute restraint stress. JOURNAL OF PSYCHOPHARMACOLOGY. 1379-1384. 2018
- Cannabinoid CB1 and CB2 receptors, and monoacylglycerol lipase gene expression alterations in the basal ganglia of patients with Parkinson's disease. NEUROTHERAPEUTICS. 459-469. 2018
- Deletion of Dlk1 increases the vulnerability to developing anxiety-like behaviors and ethanol consumption in mice. BIOCHEMICAL PHARMACOLOGY. 37-44. 2018
- Effects of cannabidiol plus naltrexone on motivation and ethanol consumption. BRITISH JOURNAL OF PHARMACOLOGY. 3369-3378. 2018
- Pharmacological regulation of cannabinoid CB2 receptor modulates the reinforcing and motivational actions of ethanol. BIOCHEMICAL PHARMACOLOGY. 227-234. 2018
- Role of the endocannabinoid system in drug addiction. BIOCHEMICAL PHARMACOLOGY. 108-121. 2018
- Cannabidiol reduces ethanol consumption, motivation and relapse in mice.. ADDICTION BIOLOGY. 1-11. 2017
- Deletion of Dlk2 increases the vulnerability to anxiety-like behaviors and impairs the anxiolytic action of alprazolam. PSYCHONEUROENDOCRINOLOGY. 134-141. 2017
- Disruption of blood-brain barrier integrity in postmortem alcoholic brain: preclinical evidence of TLR4 involvement from a binge-like drinking model.. ADDICTION BIOLOGY. 1103-1116. 2017
- Involvement of the dynorphin/KOR system on the nociceptive, emotional and cognitive manifestations of joint pain in mice.. NEUROPHARMACOLOGY. 315-327. 2017
- Is the Cannabidiol Potentially Useful for the Treatment of Neuropsychiatric and Drug-Use Disorders? . RESEARCH AND REVIEWS IN BIOSCIENCES. 112-115. 2017
- Psychological symptomatology and impaired prepulse inhibition of the startle reflex are associated with cannabis-induced psychosis.. JOURNAL OF PSYCHOPHARMACOLOGY. 1035-1045. 2017
- The Modulation of the Startle Reflex as Predictor of Alcohol Use Disorders in a Sample of Heavy Drinkers: A 4-Year Follow-Up Study.. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 1212-1219. 2017
- Increased vulnerability to ethanol consumption in adolescent maternal separated mice.. ADDICTION BIOLOGY. 847-858. 2016
- Topiramate increases the rewarding properties of cocaine in young-adult mice limiting its clinical usefulness.. PSYCHOPHARMACOLOGY. 3849-3859. 2016
- Evidence against a critical role of CB1 receptors in adaptation of the hypothalamic-pituitary-adrenal axis and other consequences of daily repeated stress. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 1248-1259. 2015
- Increased vulnerability to ethanol consumption in adolescent maternal separated mice. ADDICTION BIOLOGY. 2015
- Reduced contextual discrimination following alcohol consumption or MDMA administration in mice. PLOS ONE. 142978-142995. 2015
- Role of cannabinoid CB2 receptor in the reinforcing actions of ethanol 2015. ADDICTION BIOLOGY. 43-55. 2015
- Role of the endocannabinoid system in the emotional manifestations of osteoarthritis pain. PAIN. 2001-2012. 2015
- Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victoms. MOLECULAR NEUROBIOLOGY. 957-965. 2014
- Regulatory role of the cannabinoid CB2 receptor in stress-induced neuroinflamation in mice. BRITISH JOURNAL OF PHARMACOLOGY. 2814-2826. 2014
- Role of cannabinoid CB2 receptor in the reinforcing actions of ethanol. ADDICTION BIOLOGY. 2014
- Abnormal expression pattern of Notch receptors, ligands and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims. MOLECULAR NEUROBIOLOGY. 1-10. 2013
- Deletion of CB2 cannabinoid receptors increased voluntary ethanol consumption and ethanol self-administration associated to alterations in tyrosine hydroxylase and mu-opioid receptor in the mice brain. ADDICTION BIOLOGY. 2013
- FKBP5 alterations in the dorsal prefrontal cortex and amygdala of suicide victims . PSYCHONEUROENDOCRINOLOGY. 1251-1258. 2013
- Role of CB2 cannabinoid receptors in the rewarding, reinforcing, and physical effects of nicotine. NEUROPSYCHOPHARMACOLOGY. 2013
- Synaptic plasticity alterations associated to memory impairment induced by deletion of CB2 cannabinoid receptors . NEUROPHARMACOLOGY. 388-396. 2013
- Voluntary alcohol drinking enhances proopiomelanocortin (POMC) gene expression in nucleus accumbens shell and hypothalamus of Sardinian alcohol-preferring rats. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 131-140. 2013
- Accumbal dopamine, noradrenaline and serotonin activity after naloxone-conditioned place aversion in morphine-dependent mice.. NEUROCHEMISTRY INTERNATIONAL. 433-440. 2012
- Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection. . STROKE. 211-219. 2012
- Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels. . NEUROBIOLOGY OF AGING. 627-637. 2012
- Chronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABA(A) receptors.. BRITISH JOURNAL OF PHARMACOLOGY. 951-964. 2012
- Decreased cocaine motor sensitization and self-administration in mice overexpressing cannabinoid CB¿ receptors. . NEUROPSYCHOPHARMACOLOGY. 1749-1763. 2012
- Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects. . FRONTIERS IN BEHAVIORAL NEUROSCIENCE. 2-23. 2012
- Gene and protein alterations of FKBP5 and glucocorticoid receptor in the amygdala of suicide victims. PSYCHONEUROENDOCRINOLOGY. 2012
- Innate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol-preferring sP rats. . ADDICTION BIOLOGY. 62-75. 2012
- Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine. . NEUROBIOLOGY OF AGING. 4211-42116. 2012
- Overexpression of Cannabinoid CB2 Receptor in the Brain Induces Hyperglycaemia and a Lean Phenotype in Adult Mice.. JOURNAL OF NEUROENDOCRINOLOGY. 1106-1119. 2012
- Voluntary Alcohol Drinking Enhances Proopiomelanocortin Gene Expression in Nucleus Accumbens Shell and Hypothalamus of Sardinian Alcohol-Preferring Rats.. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 1-10. 2012
- Cannabinoid CB1 receptor regulation of GABA A and GABA B receptors. JOURNAL OF PSYCHOPHARMACOLOGY. 105-110. 2011
- Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels. NEUROBIOLOGY OF AGING. 1-11. 2011
- Deletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors. NEUROPSYCHOPHARMACOLOGY. 1489-504. 2011
- Endocannabinoid system and neuropsychiatry: in search of a neurobiological basis for the ¿two sides of the coin¿. FRONTIERS IN BEHAVIORAL NEUROSCIENCE. 1-21. 2011
- Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors. NEUROBIOLOGY OF AGING. 631-645. 2011
- Overexpression of CB2 cannabinoid receptor gene expression results in decreased vulnerability to anxiety and impaired action of alprazolam in mice. JOURNAL OF PSYCHOPHARMACOLOGY. 111-120. 2011
- CB1 receptor blockade decreases ethanol intake and associated neurochemical changes in Fawn-Hooded rats. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 131-141. 2010
- Decreased GABAa and GABAb receptor functional activity in cannabinoid CB1 receptor knock out mice. JOURNAL OF PSYCHOPHARMACOLOGY. 2010
- Depression-resistant endophenotype in mice overexpressing cannabinoid CB2 receptors. BRITISH JOURNAL OF PHARMACOLOGY. 1773-1784. 2010
- Innate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol-preferring sP rats. ADDICTION BIOLOGY. 1-17. 2010
- Overexpression of CB2 cannabinoid receptors decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice. JOURNAL OF PSYCHOPHARMACOLOGY. 1-10. 2010
- Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine. NEUROBIOLOGY OF AGING. 1-16. 2010
- Regulation of Fas receptor/Fas-associated protein with death domain apoptotic complex and associated signalling systems by cannabinoid receptors in the mouse brain. BRITISH JOURNAL OF PHARMACOLOGY. 643-656. 2010
- The cannabinoid CB1 receptor is involved in the anxiolytic, sedative and amnesic actions of benzodiazepines. JOURNAL OF PSYCHOPHARMACOLOGY. 757-765. 2010
- Métodos de evaluación de trastornos cognitivos en modelos animales. REVISTA DE NEUROLOGIA. 137-145. 2008
chapter
- Substance Use Disorders and the Endocannabinoid System: A New Narrative. Handbook of the Biology and Pathology of Mental Disorders. 1-27. 2024
- Farmacología del alcohol e intoxicación aguda. Drogodependencias 4ª ed. 117-129. 2023
- Biomarkers. Comprehensive pharmacology. 693-724. 2022
- Biomarkers. Reference Module in Biomedical Sciences. 1-31. 2021
- Estrés temprano y sus consecuencias en la vida adulta. Neurobiología del Estrés Temprano. Respuesta del estrés durante la programación de la vida temprana.. 89-106. 2020
- Cannabidiol and Cannabis Use Disorders. Cannabis Use Disorders. 31-42. 2018
- Avances en el tratamiento de los trastornos asociados al uso del cannabis. Avances en Adicciones: Claves para comprender los nuevos retos asistenciales. 33-52. 2010
- Trastorno por ansiedad y adicciones. Tratado de Patologia Dual, Reintegrando la Salud Mental. 531-560. 2010
congress communication
thesis
- PAPEL FISIOLOGICO Y UTILIDAD TERAPEUTICA DEL RECEPTOR CANNABINOIDE CB2 EN MODELOS ANIMALES DE ANSIEDAD Y DEPRESION 2011

presentations

invited conference
- Papel del cannabidiol en la regulación de las enfermedades psiquiátricas, Conferencia 2022
- Dermofarmacia: Cannabinoides y dermatologia, Conferencia 2022
- Papel del cannabidiol en la regulación de las enfermedades psiquiátricas, Conferencia 2022
- Papel del cannabidiol en la regulación de las enfermedades psiquiátricas, Conferencia 2022
- ¿Cómo llegar a ser un buen científico? Consejos para futuros investigadores, Conferencia 2018
- Actualizacion sobre el abordaje farmacoterapeutico en el manejo de trastornos depresivos y ansiedad, Conferencia 2017
- Relevancia de la investigación traslacional en Neuropsicofarmacología, Conferencia 2017
- Investigacion traslacional en Psiquiatría. Una perspectiva desde la ciencia básica, Conferencia 2017
- Papel del ligando DLK1 en la vulnerabilidad por el consumo de alcohol, Conferencia 2017
- Animal models in dual disorders: strengths and weaknesses, Conferencia 2017
- Increased vulnerability to ethanol consumption in adolescent maternal separated mice, Conferencia 2015
- Relevance of the regulation of cannabinoid system in dual patholgy, Conferencia 2015