Research Report
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academic article
- 1,3-diphenylpropan-1-ones as allosteric modulators of alpha7 nACh receptors with analgesic and antioxidant properties
- 1. Calcium Entry Through Thermosensory Channels.
- Bradykinin Induces TRPV1 Exocytotic Recruitment in Peptidergic Nociceptors.
- Captivating New Roles of F-Actin Cortex in Exocytosis and Bulk Endocytosis in Neurosecretory Cells
- Cerebrospinal fluid Presenilin-1 increases at asymptomatic stage in genetically determined Alzheimer¿s disease
- Correlation between the cellular metabolism of quercetin and its glucuronide metabolite and oxidative stress in hypertrophied 3T3-L1 adipocytes
- F-actin cytoskeleton and the fate of organelles in chromaffin cells.
- HNK-1 carrier glycoproteins are decreased in the Alzheimer¿s disease brain
- Increased Expression of Readthrough Acetylcholinesterase Variants in the Brains of Alzheimer's Disease Patients.
- Increased expression of Trpv1 in peripheral terminals mediates thermal nociception in Fabry disease mouse model.
- Induction of viral interference by IPNV-carrier cells on target cells: a cell co-culture study
- Kinetic changes of polyphenols, anthocyanins and antioxidant capacity in forced aged hibiscus ale beer
- Kinetic improvement of olive leaves' bioactive compounds extraction by using power ultrasound in a wide temperature range
- Lemon balm extract (Melissa officinalis, L.) promotes melanogenesis and prevents UVB-induced oxidative stress and DNA damage in a skin cell model
- Location of the bioactive pentacyclic triterpene ursolic acid in the membrane. A molecular dynamics study
- Looking for inhibitors of the dengue virus NS5 RNA-dependent RNA-polymerase using a molecular docking approach
- Molecular Dynamics Study of the Membrane Interaction of a Membranotropic Dengue Virus C Protein Derived Peptide
- Muscle-Type Nicotinic Receptor Modulation by 2,6-Dimethylaniline, a Molecule Resembling the Hydrophobic Moiety of Lidocaine.
- N-benzylpiperidine derivatives as alpha7 nicotinic receptor antagonists
- New transient receptor potential TRPV1, TRPM8 and TRPA1 channel antagonists from a single linear ß,¿-diamino ester scaffold
- Reelin in Alzheimer's disease, increased levels but impaired signaling: when more is less
- Restricted replication of viral hemorrhagic septicaemia virus (VHSV) in a birnavirus-carrier cell culture
- STAT3-targeted treatment with silibinin overcomes the acquired resistance to crizotinib in ALK-rearranged lung cancer
- Skin photoprotective and antiageing effects of a combination of rosemary (Rosmarinus officinalis) and grapefruit (Citrus paradisi) polyphenols
- Specific promoter deacetylation of histone H3 is conserved across mouse models of Huntington's disease in the absence of bulk changes.
- Structure and functionalities of the human c-reactive protein compared to the zebrafish multigene family of c-reactive-like proteins
- Synthesis and in vitro, ex-vivo and in vivo activity of hybrid compounds linking a potent ROS and RNS scavenger activity with diverse substrates addressed to pass across the blood-brain barrier
- TRPV1 channel modulation by hyaluronan reduces pain.
- The Location of the Protonated and Unprotonated Forms of Arbidol in the Membrane: A Molecular Dynamics Study
- Transient Receptor Potential Melastatin 8 Channel (TRPM8) Modulation: Cool Entryway for Treating Pain and Cancer.
- Tryptamine-based derivatives as Transient Receptor Potential Melastatin type-8 (TRPM8) channel modulators
- Vacunas para ¿virus de peces?
- Validation of the AlamarBlue® assay as a fast screening method to determine the antimicrobial activity of botanical extracts
- Whirlin increases TRPV1 channel expression and cellular stability.
- _Muscle-Type Nicotinic Receptor Blockade by Diethylamine, the Hydrophilic Moiety of Lidocaine.
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chapter
- BIOACTIVE COMPOUNDS FROM LIPPIA CITRIODORA: APPLICATION IN DISEASES PREVENTION
- Differential absorption of curcuminoids between free and liposomed curcumin formularions
- Rockroses (Cistus sp.) Oils
- Understanding the role of mitochondriadistribution in calcium dynamics and secretionin bovine chromaffin cells
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congress communication
- A bioplastic-based enzymatic system for decolurization of wastewater dyes: use of bacterial laccases immobilized on polyhydroxybutyrate beads.
- Amyloid-related proteins as potential CSF biomarkers for Alzheimer¿s disease
- Analysis and fractionation of Olea europaea leaf extracts for the study of their effect on obesity-related disturbances through AMPK modulation in 3T3-L1 hypertrophic adipocytes
- Aplicación de las técnicas de acoplamiento molecular al desarrollo de nuevos fármacos antitumorales
- Biodisponibilidad y metabolismo de los compuestos fenólicos de Rosmarinus officinalis
- Cerebrospinal Presenilin-1 as an early biomarker for Alzheimer's disease
- Chalcones and Chalconoids: New Allosteric Modulators of the ¿7 Nicotinic Acetylcholine Receptor (¿7 nAChR).
- Correlation between the cellular metabolism of quercetin and its glucuronide metabolite and oxidative stress in hypertrophied 3T3-L1 adipocytes
- Dengue virus capsid peptide binds specifically a HMMM model membrane
- Dengue virus in the spotlight: Capsid peptide binds specifically to a bilayer membrane model by Molecular Dynamics.
- Design and synthesis of Tryptamine-based derivatives as new TRPM8 modulators
- Diseño de inhibidores de carbapenemasas y medida de la inhibición mediante HPLC
- Diseño de nuevas líneas de antimicrobianos frente a neumococo
- El péptido de la cápside del virus dengue se une específicamente a un modelo de membrana HMMM
- Elevated Acetylcholinesterase levels by hyperphosphorylated tau over-expression
- Exploring the chamaleonic behaviour of peptides derived from the choline-binding domain of pneumococcal autolysin LytA.
- Exploring the ß-lactam ring as a central scaffold for TRPM8 modulation. International workshop
- Heteromers of the amyloid precursor protein (APP) in cerebrospinal fluid interfere in the in the quantification of sAPP¿ and sAPPß by ELISA
- Heteromers of the amyloid precursor protein (APP) in cerebrospinal fluid interfere in the in the quantification of sAPP¿ and sAPPß by ELISA
- Implicación de los genes SOCS 1 y SOCS 3 en la resistencia a la radioterapia
- Impresión en 3D de modelos de estructuras biológicas para Docencia en Biología y Biotecnología con proyección para la docencia de personas invidentes
- Impresión en 3D de modelos de estructuras biológicas para Docencia en Biología y Biotecnología con proyección para la docencia de personas invidentes
- La enfermedad de Alzheimer: desarrollo de biomarcadores diagnósticos
- Molecular determinants involved in clustering and gating patterns in KcsA
- Molecular dynamics study of the interaction of the HIV gp41 LLP2 segment with model membranes
- Novel solutions in skin beauty
- Optimization and characterization of natural extracts of mediterraneal plants obtained by ultrasound-based technology
- PL-06 Food Ingredients, Cancer and Foodomics
- Permeability study of rosemary extract in human intestinal colon adenocarcinoma CACO-2 cells by UHPLC-ESI-UHR-Q-TOF-MS.
- Péptido de la cápsida del virus del dengue se une especificamente a un modeolo de membrana HMMM
- Screening for the antiproliferative activity of extracts of marine invertebrates on human colon cancer cell lines
- Soluble complexes of Presenilin-1 in cerebrospinal fluid are a potential biomarker for Alzheimer¿s disease
- Soluble complexes of Presenilin-1 in cerebrospinal fluid are a potential biomarker for Alzheimer¿s disease
- Study of the synergistic behaviour of the antiproliferative capacity of Olea europaea polyphenols in human cancer cell models
- Targeting the pneumococcal cell wall. Effects of externally added proteins containing Choline-Binding Modules (CBMs) on the growth of Streptococcus pneumoniae
- Un estudio de dinámica molecular en la interacción segmento gp41 LLP2 del HIV con membranas modelo
- Una terapia enzimática de base nanotecnologica induce muerte celular en líneas celulares de cáncer
- Understanding the Role of Mitochondria Distribution in Calcium-Induced Exocytosis in Bovine Chromaffin Cells
- Unraveling the structural chameleonic behavior of peptides derived from the choline-binding repeats of pneumococcal autolysin LytA
- Zic2 induces the accumulation of ß-catenin to promote axon midline repulsion
- ß-amyloid compromises Reelin signaling in Alzheimer¿s disease
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event
- II JORNADA DE INVESTIGACION BIOMEDICA (HGUE-IBMC) (Congress Organization)
- III JORNADAS "Y TU, ¿QUE INVESTIGAS?" (Congress Organization)
- IV INTERNATIONAL CONGRESS ON RESEARCH AND INNOVATION IN NEURODEGENERATIVE DISEASES, CIIIEN (Congress Organization)
- VIII JORNADAS SAN ALBERTO MAGNO (Congress Organization)
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invited conference
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operating licence
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patent
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person
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person (active)
- CRIADO HERRERO, MANUEL
- CUCHILLO IBAÑEZ, INMACULADA
- DEVESA GINER, ISABEL
- ENCINAR HIDALGO, JOSÉ ANTONIO
- FERNÁNDEZ BALLESTER, GREGORIO JOAQUIN
- FERNÁNDEZ CARVAJAL, ASIA
- FERRER MONTIEL, ANTONIO VICENTE
- GARCIA MORALES, MARIA DEL PILAR
- GONZALEZ ROS, JOSE MANUEL
- GUTIERREZ PEREZ, LUIS MIGUEL
- HERRANZ LOPEZ, MARIA DOLORES
- MICOL MOLINA, VICENTE
- MORENILLA PALAO, MARIA CRUZ
- PEREZ GARCIA-ESTAÑ, LUIS
- REIG MACIA, JUAN ANTONIO
- SACEDA SANCHEZ, MIGUEL
- SAEZ VALERO, JAVIER
- SANZ MORALES, JESUS MIGUEL
- VILLALAIN BOULLON, JOSÉ
- VILLANUEVA ROIG, JOSE HELIODORO
- VINIEGRA BOVER, SALVADOR
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research project
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technological support
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thesis
- IDENTIFICATION AND CHARACTERISATION OF WHIRLIN AS A NOVEL MODULATOR OF PRPV1
- CHARACTERIZATION AND EVALUATION OF TRPV1 AND TRPM8 ANTAGONISTS AS POTENTIAL THERAPEUTIC TOOLS FOR TREATING PAIN
- DIFFERENTIAL MECHANISM OF TRPV1 SENSITIZATION IN PEPTIDERGIC AND NONPEPTIDERGIC NOCICEPTORS
- ESTUDIOS DE CONDUCCIÓN Y SELECTIVIDAD IÓNICAS BASADOS EN UN CANAL DE POTASIO MODELO: KCSA
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thrid party project