Anualidad
Research Activity Report
Plant-Derived Natural Productsfor the Treatment of Bacterial Infections
TYK2 and IFNAR1 protein-protein interaction as a novel approach to prevent inflammation in early type 1 diabetes
Distribution of NMDA receptors in cortex of Alzheimer ¿s disease patients: synaptic versus extrasynaptic membranes
XVI JORNADA DE SAN ALBERTO MAGNO (Congress Organization)
IX CONGRESO RED ESPAÑOLA DE CANALES IONICOS (Congress Organization)
Role of Orai-family channels in the activation and regulation of transcriptional activity
Endoplasmic reticulum stress triggers unfolded protein response as an antiviral strategy of teleost erythrocytes
NMDARs in Alzheimer's Disease: Between Synaptic and Extrasynaptic Membranes
Implications of somatotroph axis in the behaviour of silent corticotroph tumours
Profilin1 is required for abscission during late cytokinesis of chondrocytes
Multi-omics evaluation of the activity of encapsulated olive leaf extracts in obesity management
Changes in the Kv1.3 pharmacology upon the association with KCNE4
Functional role of the calmodulin- and inositol 1,4,5-trisphosphate receptor-binding (CIRB) site of TRPC6 in human platelet activation
KCNE4-dependent modulation of Kv1.3 pharmacology
Peripheral blood biomarkers at the single-cell resolution in Huntington's disease
Orai1a, but not Orai1ß, co-localizes with TRPC1 and is required for its plasma membrane location and activation in HeLa cells
Two-pore channel 2 (TPC2) modulates store-operated Ca2+ entry
Circulating cytokines post beta-cell loss in transgenic mouse model of type 1 diabetes: Impact on alpha-to-beta cell transdifferentiation
STIM1 and STIM2 are located in the acidic Ca2+ stores and associates with Orai1 upon depletion of the acidic stores in human platelets
Analysis of Anxiety Caused by Fasting in Obesity Patients Using EEG Signals
Development of new drug delivery systems based on polymeric nanofibers for glioblastoma treatment
NMDARs in Alzheimer¿s disease: between synaptic and extrasynaptic membranes
From Animal Free to Feeder Free Conditions: The Desired Derivation Process for Human Embryonic Stem Cells
Retinal dysfunction in Huntington¿s disease mouse models is characterized by an early photoreceptor degeneration and a late neuroinflammation
CAPN1 (Calpain1)-Dependent Cleavage of STIM1 (Stromal Interaction Molecule 1) Results in an Enhanced SOCE (Store-Operated Calcium Entry) in Human Neonatal Platelets
The multicomponent Passerini reaction as a means of accessing diversity in structure, activity and properties: soft and hard vanilloid/cannabinoid modulators
ANTIVIRAL ACTIVITY OF PLANT EXTRACTS AGAINST REDSPOTTED GROUPER NERVOUS NECROSIS VIRUS.
Genomic organization of profilin-III and evidence for a transcript expressed exclusively in testis
FKBP25 and FKBP38 regulate non-capacitative calcium entry through TRPC6
Acidic NAADP-releasable Ca2+ compartments in the megakaryoblastic cell line MEG01
MODIFIED SYNAPTIC AND EXTRASYNAPTIC DISTRIBUTION OF NMDA RECEPTORS IN CORTEX OF ALZHEIMER ¿S DISEASE INDIVIDUALS
I WORKSHOP ¿INMUNOLOGIA, NUTRICION Y BIENESTAR EN ACUICULTURA¿ (Congress Organization)
Evaluation of Bioactive Effects of Five Plant Extracts with Different Phenolic Compositions against Different Therapeutic Targets
Role of STIM2 in cell function and physiopathology
SARS-CoV-2 genomic variations linked to COVID-19 severity identified through comprehensive analysis of viral quasispecies
Evolución del plan formativo en el marco de un programa para la realización de trabajos de fin de grado interdisciplinares
STIM1 tyrosine-phosphorylation is required for STIM1-Orai1 association in human platelets
Zic2 regulates cytoskeleton dynamics in the growth cone of Retinal Ganglion Cells
Endothelial cells and the regulation of platelet function
Synaptic and extrasynaptic distribution of NMDA receptors in the cortex of Alzheimer's disease patients
Dietary polyphenols for appetite and satiety regulation in obese subjects.
Development of novel drug delivery systems based on polymeric nanofibres for the treatment of glioblastoma
Identification of novel inhibitors of plant GH3 IAA-amido synthetases through molecular docking studies
Retinal spontaneous activity and optic nerve myelination
Intestinal permeability study of two dietary polyphenols with anorexigenic effects through GLP-1 modulation in Caco-2 cell monolayers
La gestión de la demanda de las pruebas: un reto en el nuevo modelo de medicina de laboratorio
Retinal dysfunction in Huntington's disease mouse models concurs with local gliosis and microglia activation
Relevance of USP8 mutations in the pathogenesis of pituitary tumours of the corticotroph lineage
Long-term mTOR inhibitors administration evokes altered calcium homeostasis and platelet dysfunction in kidney transplant patients
Identification of novel modulators of TRPM8 through virtual screening and molecular dynamics
Role of mTOR1 and mTOR2 complexes in MEG-01 physiology
EPIGENETIC STUDY OF FISH ERYTHROCYTES FOR THE SEARCH OF INNOVATIVE ANTIVIRAL SOLUTIONS IN AQUACULTURE
Relationship between calcium mobilization and platelet ¿- and ¿-granule secretion. A role for TRPC6 in thrombin-evoked ¿-granule exocytosis
Histone H3 variants are associated with distinctive glioma entities
Differential functional role of Orai1 variants in constitutive Ca2+ entry and calcification in luminal breast cancer cells
Linking obesity-related hormonal and EGG profiles in the context of appetite and satiety
Caracterización del sistema oxitocinérgico: dinámica y liberación
Relevance of oxidative stress and inflammation in frailty based on human studies and mouse models
Localization, aggregation, and interaction of glycyrrhizic acid with the plasma membrane
OPTIMIZACIÓN DE LA EXTRACCIÓN DE POLIFENOLES DE LA PAJA DEL ARROZ: CONVIRTIENDO UN PROBLEMA MEDIOAMBIENTAL EN UNA POTENCIAL SOLUCIÓN.
Differential expression of Orai1 variants in the lipid rafts domain of the plasma membrane, P67
Polyphenols and metabolism: from present to future challenges
Automated Computerized-Based Intervention to Identify Hypomagnesemia in Primary Care Patients With Arrhythmia
Interaction between the linker, pre-S1 and TRP domains determines folding, assembly and trafficking of TRPV channels
Nanofibras poliméricas como sistema de liberación de moléculas activas
The polybasic lysine-rich domain of plasma membrane-resident STIM1 is essential for the modulation of store-operated divalent cation entry by extracellular calcium
The use of fish RBCs as cellular targets for novel vaccine prototypes: from immune system stimulation to cell-to-cell communication
Impact of melatonin supplementation on sports performance and circulating biomarkers in highly trained athletes: A systematic review of randomized controlled trials
¿Es la neurocosmética el futuro del cuidado integral?
Structural determinants of 5',6'-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel
Bisphenol F and Bisphenol S in a Complex Biomembrane: Comparison with Bisphenol A
Centenarians overexpress pluripotency-related genes
Regulation of Platelet Function by Orai, STIM and TRP
DIRECT CONVERSION AND MICROFLUIDIC CHAMBERS AS TOOLS TO STUDY THE IN-VIVO SKETCH OF HUMAN SENSORY NEURONS
An untargeted metabolomics approach applied to the study of the bioavailability and metabolism of three different bioactive plant extracts in human blood samples.
TRPC6 participates in the regulation of cytosolic basal calcium concentration in murine resting platelets
The application of plasmid DNA constructs encoding antiviral proteins as potential therapeutics against viral infections in salmonid aquaculture
Equipo de investigación: elaboración de videos temáticos con competencias transversales.
Exploring the Therapeutic Potential of Marine Compounds in the Tumor Microenvironment of HCT-116 Cells and Their Effects on Epithelial-Mesenchymal Transition
Location and interaction of idebenone and mitoquinone in a membrane similar to the inner mitochondrial membrane. Comparison with ubiquinone 10
Desarrollo De Nuevos Sistemas De Liberación De Antineoplásicos Basados En Biopolímeros Para El Tratamiento De Glioblastoma
Immunophilins are Involved in the Altered Platelet Aggregation Observed in Patients with Type 2 Diabetes Mellitus
SARAF overexpression impairs thrombin-evoked Ca2+ homeostasis in neonatal platelets
Cancer and Obesity: Crosstalk Between Adipocytes and Cancer Cells in the Tumor Microenvironment as a New Target in Cancer Research
Advancements of nanocarriers for brain targeting and limitations in clinical translation
4--trans-Hydorxyproline derivatives as TRPM8 antagonists
The color: the way they exist in nature and its biological and artistical signifiance.
Analysis of Lemon Verbena Polyphenol Metabolome and Its Correlation with Oxidative Stress under Glucotoxic Conditions in Adipocyte
Activos mientras estudiamos, merece la pena asistir a clase
EFHB is a novel cytosolic Ca2+ sensor that modulates STIM1-SARAF interaction
. Structural-Based Virtual Screening of in-house compound collections to identify TRPM8 ligands
Transplantation of dorsal root ganglia overexpressing the NaChBac sodium channel improves locomotion after complete SCI
Specific targeting of the NRF2/ß-TrCP axis promotes beneficial effects in NASH
Citrullinating enzyme PADI4 and transcriptional repressor RING1B bind in cancer cells
The canonical transient receptor potential 6 (TRPC6) channel is sensitive to extracellular pH in mouse platelets
Altered plasma levels of the SARS-CoV-2-related proteins ACE2 and TMPRSS2 in patients with Crohn's disease.
Development of a Chlamydomonas-based protein expression system for the production of vaccines against viral diseases of fish
Molecular interplay between platelets and the vascular wall in thrombosis and hemostasis
Thrombotic Alterations under Perinatal Hypoxic Conditions: HIF and Other Hypoxic Markers
Células madre.Posibilidades terapéuticas
Genetic characterisation of SARS-CoV-2 populations associated with clinical severity of COVID-19 disease
/. 4-trans-Hydorxyproline derivatives as TRPM8 modulators.
IDENTIFICATION OF P21, P20 AND P17 AS BROWNING-INDUCING POLYPHENOLS IN HUMAN SGBS HYPERTROPHIC ADIPOCYTES
Enfoques de investigación para la comprensión y tratamiento de la obesidad y su relación con el cáncer
Unveiling the Binding between the Armadillo-Repeat Domain of Plakophilin 1 and the Intrinsically Disordered Transcriptional Repressor RYBP
ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial-to-mesenchymal transition in cranial neural crest specification
Dusky grouper massive die-off in a Mediterranean marine reserve
Dynamic interaction of SARAF with STIM1 and Orai1 to modulate store-operated calcium entry
Effects of Obesity on Tumor Behaviour: Insights from Co-Culture Models
Capacitative and non-capacitative signaling complexes in human platelets
PTPRK regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity.
Feed pellets containing mCherry transformed Chlamydomonas reinhardtii as a proof of concept for protein-based vaccine delivery in rainbow trout
Stromal Interaction Molecules 1 and 2 Are Key Regulators of Autoreactive T Cell Activation in Murine Autoimmune Central Nervous System Inflammation
THERMO TRP ION CHANNELS AS A KEY MOLECULAR AND FUNCTIONAL LANDMARK FOR NEUROPATHIC PAIN TRANSDUCTION IN SUBSETS OF SOMATOSENSORY NEURONS
IN-FEED PLANT EXTRACTS AS NOVEL ANTIVIRAL THERAPEUTICS AGAINST VIRAL NERVOUS NECROSIS INFECTION IN SEA BASS
Silibinin is a suppressor of the metastasis-promoting transcription factor ID3
Distribución de los receptores de NMDA en Alzheimer
Molecular mapping of KCNE4-dependent regulation of Kv1.3
EMOTION: un máster universitario con vocación innovadora e internacional
ThermoTRP ion channels as a key molecular and functional landmark forchemotherapy-induced neuropathic pain
LIBERACIÓN SOMATODENDRÍTICA DE OXITOCINA EN EL HIPOTÁLAMO: PAPEL DE PROTEÍNAS SNARE NO CANÓNICAS
Fluorescence-Based Measurements of the CRAC Channel Activity in Cell Populations
SÍNTESIS Y CARACTERIZACIÓN DE NANOFIBRAS POLIMÉRICAS COMO SISTEMAS DE LIBERACIÓN DE ANTINEOPLÁSICOS EN UN MODELO IN VITRO DE GLIOBLASTOMA
Papel del calcio en la secreción de los gránulos alfa y densos en plaquetas humanas
SARS-CoV-2 genetic factors associated with COVID-19 severity through whole-genome quasispecies analysis
Identification of new targets for glioblastoma therapy based on a DNA expression microarray
PEQUEÑAS MOLÉCULAS INHIBIDORAS DE LA INTERACCIÓN PROTEÍNA-PROTEÍNA ENTRE TYK2 E IFNAR1 COMO UNA NUEVA ESTRATEGIA PARA LA PREVENCIÓN DE LA INFLAMACIÓN EN LOS ESTADIOS INICIALES DE LA DIABETES TIPO 1
Functional Consequences of Integrin Gene Mutations in Mice
Steady-state and time-resolved fluorescent methodologies to characterize the conformational landscape of the selectivity filter of K+ channels
Mecanismo molecular y evidencia clínica de la modulación tópica de la neuropatía por quimioterapia Antonio Ferrer Montiel
Acute antioxidant response to two types of exercises: 2000 m run vs. Burpee test
ANTIVIRAL ACTIVITY OF PLANT EXTRACTS AGAINST VIRAL HEMORRHAGIC SEPTICEMIA VIRUS
Hacia un futuro sostenible: uso de inteligencia artificial para optimizar la obtención de polifenoles en residuos de paja de arroz
Deciphering ACE2 and TMPRSS2 changes in Down syndrome and Alzheimer's dementia: concerns regarding COVID-19
Evolución del plan formativo en el marco de un porgrama para la realización de TFG Interdisciplinares
NaV channels as key therapeutic targets for oxaliplatin-induced neuropathy: alterations in male and female rat sensory neurons
Innovaciones a pequeña escala, impactos a gran escala
Peptides inhibiting isoforms phospholipase C beta show a potential anti-inflammatory activity
Polyphenols reverse hyperglycemia-induced adipocyte dysfunction: an omic study
Proper Frequency of Perinatal Retinal Waves is Essential for The Precise Wiring of Visual Axons in Non-Image Forming Nuclei
Design and Validation of Novel Potential Antiperspirant Peptides Blocking M3-G¿q Sweat Signaling Cascade
GPM6a as a novel target protein to isolate brain-derived extracellular vesicles
STIM2 regulates capacitive Ca2+ entry in neurons and plays a key role in hypoxic neuronal cell death
Fusión de membranas inducida por los rhabdovirus de pez (SVCV y VHSV)
pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties.
Therapeutic potential of marine compounds in the tumour microenvironment in HCT-116 tumour cells and the influence on the epithelial-mesenchymal transition
Orai1a but not Orai1ß participates in constitutive Ca2+ entry and luminal breast cancer cell physiology, P69
46 CONGRESO DE LA SOCIEDAD ESPAÑOLA DE BIOQUIMICA Y BIOLOGIA MOLECULAR (Congress Organization)
Cytotoxic and cytostatic effect of a flavone formulation derived from olive leaf in breast cancer cellular models
Aplicación de construcciones plasmídicas codificantes de proteínas antivirales como potencial terapéutico contra infecciones virales en la acuicultura de salmónidos
neuroeducación Alimentaria: educando el gusto a través de prescripciones culinarias multisensoriales
Unveiling the role of thermo TRP ion channels and neuronal excitability in paclitaxel­induced peripheral neuropathy: a molecular and functional perspective
Localization and Aggregation of Honokiol in the LipidMembrane
DEVELOPMENT OF A CHLAMYDOMONAS-BASED VACCINE AGAINST SALMONID ALPHAVIRUS (SAV2) TO IMPROVE THE SUSTAINABILITY OF RAINBOW TROUT AQUACULTURE.
Efectos del consumo de café y sus subproductos en las alteraciones relacionadas con la obesidad: una revisión actualizada
ANTIVIRAL PROTEINS AS POTENTIAL THERAPEUTICS AGAINST VIRAL INFECTIONS IN SALMONID AQUACULTURE
Store-Operated Calcium Entry in Breast Cancer Cells Is Insensitive to Orai1 and STIM1 N-Linked Glycosylation
FKBP52 is involved in the regulation of SOCE channels in the human platelets and MEG 01 cells
Structural and functional insights into allosteric communication in the modulation of KirBac1.1 by pH
Stanniocalcins expression is altered in thrombotic patients
Targeting Cold-Sensitive TRPM8 Ion Channels for the Alleviation of Migraine-Related Symptomatology
Structural and functional insights into allosteric communication in the modulation of KirBac1.1 by pH,
Orais and STIMs: physiological mechanisms and disease
Cytoskeletal and scaffolding proteins as structural and functional determinants of TRP channels
The Role of Nicotinic Receptors on Ca2+ Signaling in Bovine Chromaffin Cells
Patterns of circulating cytokines after 2 types of exercise in active type-1 diabetic patients
Synaptic and extrasynaptic distribution of NMDA receptors in cortex of Alzheimer¿s disease patients
In silico screening of compounds to modulate Nav1.1 in Dravet syndrome
Similarities and Differences between the Orai1 Variants: Orai1a and Orai1ß
RDF description of Bioquímica y Biología Molecular 2024 - http://research.umh.es/vivo/pub/memoria/2024/org_102