Research Organization
type: Class

Anualidad
type: Class

2022
type: Class

Research Activity Report
type: Class

RDF description of Moléculas bioactivas 2022 - http://research.umh.es/vivo/pub/memoria/2022/gi_1079
type: Document
rights: termsOfUse
date: 2026-05-25T01:48:00
publisher: Moléculas bioactivas 2022

Moléculas bioactivas 2022
type: 2022
includes: Electrospun fibers of Poly(methyl vinyl ether-alt- maleic anhydride) and L-Menthol for treatment of plantar fasciitis
includes: In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening
includes: Intra-variability in IB4- and IB4+ DRG neurons: a population of models study
includes: New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models
includes: EQC2021-007485-P
includes: Thermo TRP ion channels as a key molecular and functional landmark for neuropathic pain transduction in subsets of somatosensory neurons
includes: Paclitaxel and Oxaliplatin Sensitizing Effects and Sex Differences on Pre-Clinical In vitro Models of Chemotherapy-Induced Peripheral Neuropathy
includes: TRPM8 channel antagonists for relieving pain in chemotherapy-induced peropheral neuropathy
includes: PROMETEO/2021/031
includes: IDIFEDER/2021/036
includes: Pre-clinical model for the study of gender dimorphism in inflammatory processes during a migraine attack
includes: GRISOLIA
included: Moléculas bioactivas
includes: New chiral heterocyclic amino acid derivatives as TRPM8 antagonists.
includes: ThermoTRP channels in pain sexual dimorphism: new insights for drug intervention.
includes: PDC2022133405I00
includes: Conformational buffering underlies functional selection in intrinsically disordered protein regions
includes: Diseño computacional y validación funcional de nuevos péptidos moduladores de las isoformas fosfolipasa C beta
includes: INNTA1/2021/11
includes: ¿Qué parte del cerebro me avisa del picor?
includes: Caracterización de un péptido de diseño con potencial inhibidor del virus del ZIKA
most specific type: Research Organization
includes: RED2018-102628-T
includes: In vitro pre-clinical nociceptor model: useful tool for modelling Chemotherapy Induced-Neuropathic Pain (CIPN)
includes: Los canales iónicos Thermo TRP como clave molecular y funcional para la transducción del dolor neuropático en las neuronas somatosensoriales
includes: In vitro pre-clinical nociceptor model: useful tool for modelling Chemotherapy Induced-Neuropathic Pain
includes: Evaluación del dimorfismo sexual en la sensibilización de TRPA1 durante una crisis de migraña
includes: Development of a compound as neurocosmetic ingredient to alleviate allodynia symptoms induced by chemotherapy-
relates: Moléculas bioactivas
includes: Oxaliplatin time course effect on a pre-clinical in vitro model of male and female rat DRG neurons.
includes: Amino acid-derived ß¿lactams: TRPM8 antagonists with analgesic activity in different pain models.
includes: New chiral heterocyclic compounds with potent TRPM8 antagonist activity
includes: ANTALGENICS1.15ET
includes: FERNÁNDEZ CARVAJAL, ASIA
includes: INNVA2/2022/8
includes: FERNÁNDEZ BALLESTER, GREGORIO JOAQUIN
includes: Modelos traslacionales de dolor: Investigación preclínica sobre el dimorfismo sexual de la migraña crónica.
includes: Design of non-immunogenic peptides that prevent the activation of SARS-CoV-2 nsp14 and nsp16 proteins
includes: Diseño de péptidos moduladores de las isoformas fosfolipasa C beta
includes: TRPV1 in chronic pruritus and pain: Soft modulation as a therapeutic strategy
includes: Discovery of new TRPM8 modulators and their therapeutic potential
includes: PROSPERA1.22CC
includes: Design of non-immunogenic peptides that prevent the activation of SARS-CoV_2 nsp14 and nsp16 proteins
type: Research Activity Report
includes: Testosterone-TRPM8 interactions drive pain resilience in a mouse model of chronic migraine
includes: con 135332.0
type: Thing
includes: RTI2018-097189-B-C21
includes: Conversión directa de fibroblastos fetales de pulmon a neuronas sensoriales
includes: Direct conversion of human foetal lung fibroblasts to sensory neurons.
includes: con 134587.0
includes: ANTALGENICS1.20SC
type: Anualidad
includes: Direct conversion of foetal lung fibroblasts to sensory neurons
includes: FERRER MONTIEL, ANTONIO VICENTE
includes: ß-Lactam TRPM8 antagonist RGM8-51 displays analgesic activity in different animal models
includes: Androgenic TRPM8 1 activity drives sexual dimorphism in a murine model of chronic migraine.
includes: GAN956477
includes: Paclitaxel in vitro reversibly sensitizes the excitability of IB4(-) and IB4(+) sensory neurons from male and female rats
includes: Cytoskeleton altering drugs and peripheral nerve neurons as a combinatorial therapy for spinal cord injury
most specific type: 2022
includes: Gender differences in scratching behaviour
includes: Paclitaxel and Oxaliplatin Effects on Pre-clinical In vitro Models of Chemotherapy-Induced Peripheral Neuropathy of Male and Female Rat DRG Neurons
includes: A topical formulation of a soft TRPV1 antagonist (AG1549) alleviates chemotherapyinduced peripheral neuropathy symptoms.
includes: Migraine-related vulnerability involves TRPA1 and androgenic TRPM8 activity in mice
includes: VIDIF22/19
type: Research Organization
includes: Direct conversion of human fibroblasts to sensory neurons
includes: DESCUBRIMIENTO DE NUEVOS MODULADORES DE TRPM8 Y SU POTENCIAL TERAPÉUTICO
includes: Identificación y Caracterización de nuevos moduladores de TRPM8.
includes: PID2021126423OBC21
includes: Modelo pre-clínico para el estudio de las diferencias de género en procesos inflamatorios durante una crisis de migraña
includes: BCNPEPTIDES1.21SC
includes: ¿CÓMO SE DESENCADENA EL DOLOR TRAS LA QUIMIOTERAPIA? ESTUDIANDO LOS CAMBIOS MOLECULARES PRODUCIDOS POR EL PACLITAXEL SOBRE LOS NOCICEPTORES UTILIZANDO UN MODELO IN VITRO PRECLÍNICO

Electrospun fibers of Poly(methyl vinyl ether-alt- maleic anhydride) and L-Menthol for treatment of plantar fasciitis
type: BFO_0000002
included: Moléculas bioactivas 2022
type: ConferencePoster
type: Thing
type: IAO_0000030
type: Anualidad
type: BFO_0000001
type: Conference
type: BFO_0000031
type: Document
type: 2022

In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening
type: IAO_0000030
included: Moléculas bioactivas 2022
type: Anualidad
type: Thing
type: BFO_0000031
type: AcademicArticle
type: BFO_0000002
type: 2022
type: BFO_0000001
type: Article
type: Document

Intra-variability in IB4- and IB4+ DRG neurons: a population of models study
type: BFO_0000031
type: Document
type: ConferencePoster
type: 2022
included: Moléculas bioactivas 2022
type: BFO_0000002
type: Anualidad
type: BFO_0000001
type: IAO_0000030
type: Conference
type: Thing

New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models
type: BFO_0000002
type: Thing
type: Article
type: IAO_0000030
type: Document
type: Anualidad
type: BFO_0000031
type: 2022
type: BFO_0000001
type: AcademicArticle
included: Moléculas bioactivas 2022

EQC2021-007485-P
type: OBI_0000011
included: Moléculas bioactivas 2022
type: Anualidad
type: Relationship
type: BFO_0000002
type: ProyectoInvestigacion
type: Project
type: BFO_0000001
type: Year2023
type: BFO_0000015
type: Thing
type: BFO_0000020
type: BFO_0000003
type: ERO_0000014
type: Grant
type: 2022
type: Proyecto

Thermo TRP ion channels as a key molecular and functional landmark for neuropathic pain transduction in subsets of somatosensory neurons
type: BFO_0000002
type: Anualidad
type: IAO_0000030
type: Document
type: BFO_0000031
type: Conference
type: Thing
type: 2022
type: ConferencePoster
type: BFO_0000001
included: Moléculas bioactivas 2022

Paclitaxel and Oxaliplatin Sensitizing Effects and Sex Differences on Pre-Clinical In vitro Models of Chemotherapy-Induced Peripheral Neuropathy
type: Article
type: 2022
type: ConferencePaper
type: BFO_0000002
type: Conference
type: Document
type: BFO_0000031
type: Thing
type: IAO_0000030
type: BFO_0000001
included: Moléculas bioactivas 2022
type: Anualidad

TRPM8 channel antagonists for relieving pain in chemotherapy-induced peropheral neuropathy
type: Article
type: Anualidad
type: ConferencePaper
included: Moléculas bioactivas 2022
type: 2022
type: Document
type: IAO_0000030
type: BFO_0000002
type: Conference
type: Thing
type: BFO_0000031
type: BFO_0000001

PROMETEO/2021/031
type: ERO_0000014
type: Anualidad
type: Year2024
type: BFO_0000003
type: ProyectoInvestigacion
type: Grant
type: Thing
type: BFO_0000002
type: Year2023
type: Relationship
type: 2022
type: BFO_0000001
included: Moléculas bioactivas 2022
type: Year2021
type: OBI_0000011
type: Project
type: BFO_0000020
type: Proyecto
type: BFO_0000015

IDIFEDER/2021/036
type: 2022
type: Proyecto
type: BFO_0000020
type: BFO_0000001
type: Anualidad
type: Thing
type: BFO_0000003
type: Relationship
type: Year2021
type: OBI_0000011
type: BFO_0000015
type: Project
type: ProyectoInvestigacion
type: ERO_0000014
included: Moléculas bioactivas 2022
type: Grant
type: BFO_0000002

Pre-clinical model for the study of gender dimorphism in inflammatory processes during a migraine attack
type: ConferencePoster
type: Anualidad
type: BFO_0000031
type: BFO_0000001
type: Document
included: Moléculas bioactivas 2022
type: IAO_0000030
type: 2022
type: BFO_0000002
type: Thing
type: Conference

GRISOLIA
type: Grant
type: Year2021
type: BFO_0000001
type: BFO_0000003
type: Year2019
type: Relationship
type: Project
type: ProyectoInvestigacion
type: Proyecto
type: OBI_0000011
included: Moléculas bioactivas 2022
type: Thing
type: BFO_0000015
type: 2022
type: ERO_0000014
type: Anualidad
type: BFO_0000002
type: BFO_0000020
type: Contratacion
type: Year2020

Moléculas bioactivas
type: BFO_0000004
type: ResearchOrganization
type: BFO_0000001
type: ResearchOrganizationActive
includes: Moléculas bioactivas 2022
type: Organization
related by: Moléculas bioactivas 2022
type: Agent
type: BFO_0000002
type: Thing

New chiral heterocyclic amino acid derivatives as TRPM8 antagonists.
type: Thing
included: Moléculas bioactivas 2022
type: BFO_0000001
type: IAO_0000030
type: Document
type: BFO_0000031
type: Anualidad
type: BFO_0000002
type: ConferencePaper
type: Conference
type: 2022
type: Article

ThermoTRP channels in pain sexual dimorphism: new insights for drug intervention.
type: Article
type: BFO_0000001
included: Moléculas bioactivas 2022
type: IAO_0000030
type: BFO_0000031
type: AcademicArticle
type: Thing
type: 2022
type: Anualidad
type: BFO_0000002
type: Document

Conformational buffering underlies functional selection in intrinsically disordered protein regions
type: BFO_0000002
included: Moléculas bioactivas 2022
type: Thing
type: Document
type: BFO_0000001
type: Article
type: IAO_0000030
type: Anualidad
type: BFO_0000031
type: AcademicArticle
type: 2022

Diseño computacional y validación funcional de nuevos péptidos moduladores de las isoformas fosfolipasa C beta
type: ConferencePoster
included: Moléculas bioactivas 2022
type: IAO_0000030
type: Anualidad
type: Document
type: Thing
type: BFO_0000031
type: BFO_0000001
type: Conference
type: BFO_0000002
type: 2022

INNTA1/2021/11
type: Anualidad
type: BFO_0000001
type: Project
type: ERO_0000014
type: BFO_0000003
type: 2022
type: BFO_0000002
type: Relationship
type: Thing
type: BFO_0000015
type: ProyectoInvestigacion
type: OBI_0000011
type: Year2021
type: BFO_0000020
type: Year2023
included: Moléculas bioactivas 2022
type: Proyecto
type: Grant

¿Qué parte del cerebro me avisa del picor?
type: Anualidad
type: BFO_0000031
type: IAO_0000030
type: Article
type: 2022
included: Moléculas bioactivas 2022
type: Document
type: Thing
type: BFO_0000002
type: AcademicArticle
type: BFO_0000001

Caracterización de un péptido de diseño con potencial inhibidor del virus del ZIKA
type: Document
included: Moléculas bioactivas 2022
type: 2022
type: BFO_0000002
type: IAO_0000030
type: ConferencePoster
type: Thing
type: Conference
type: Anualidad
type: BFO_0000031
type: BFO_0000001

RED2018-102628-T
type: Year2021
type: BFO_0000002
type: ProyectoInvestigacion
type: Anualidad
type: Thing
type: Grant
type: Proyecto
type: OBI_0000011
type: BFO_0000001
type: BFO_0000015
type: ERO_0000014
type: Relationship
type: 2022
type: BFO_0000003
included: Moléculas bioactivas 2022
type: Year2020
type: BFO_0000020
type: Project

In vitro pre-clinical nociceptor model: useful tool for modelling Chemotherapy Induced-Neuropathic Pain (CIPN)
type: Event
type: BFO_0000003
included: Moléculas bioactivas 2022
type: BFO_0000015
type: BFO_0000001
type: Anualidad
type: InvitedTalk
type: InvitedConference
type: 2022
type: Presentation
type: Thing

Los canales iónicos Thermo TRP como clave molecular y funcional para la transducción del dolor neuropático en las neuronas somatosensoriales
type: Anualidad
type: BFO_0000001
included: Moléculas bioactivas 2022
type: 2022
type: ConferencePoster
type: Conference
type: BFO_0000031
type: Document
type: Thing
type: IAO_0000030
type: BFO_0000002

In vitro pre-clinical nociceptor model: useful tool for modelling Chemotherapy Induced-Neuropathic Pain
type: BFO_0000001
included: Moléculas bioactivas 2022
type: Document
type: ConferencePaper
type: Anualidad
type: Conference
type: 2022
type: Thing
type: Article
type: BFO_0000031
type: IAO_0000030
type: BFO_0000002

Evaluación del dimorfismo sexual en la sensibilización de TRPA1 durante una crisis de migraña
type: IAO_0000030
type: Conference
type: BFO_0000001
type: BFO_0000002
type: 2022
type: ConferencePoster
type: Document
included: Moléculas bioactivas 2022
type: Thing
type: Anualidad
type: BFO_0000031

Development of a compound as neurocosmetic ingredient to alleviate allodynia symptoms induced by chemotherapy-
type: Document
type: Anualidad
type: BFO_0000031
type: Thing
type: IAO_0000030
type: 2022
type: ConferencePoster
type: Conference
type: BFO_0000002
included: Moléculas bioactivas 2022
type: BFO_0000001

Oxaliplatin time course effect on a pre-clinical in vitro model of male and female rat DRG neurons.
type: Anualidad
type: IAO_0000030
type: BFO_0000002
type: ConferencePaper
type: Conference
type: Thing
type: 2022
type: Document
type: Article
type: BFO_0000031
included: Moléculas bioactivas 2022
type: BFO_0000001

Amino acid-derived ß¿lactams: TRPM8 antagonists with analgesic activity in different pain models.
type: 2022
type: BFO_0000001
type: ConferencePoster
type: BFO_0000002
included: Moléculas bioactivas 2022
type: Thing
type: BFO_0000031
type: IAO_0000030
type: Anualidad
type: Document
type: Conference

New chiral heterocyclic compounds with potent TRPM8 antagonist activity
type: 2022
included: Moléculas bioactivas 2022
type: IAO_0000030
type: Conference
type: Thing
type: ConferencePaper
type: Document
type: BFO_0000002
type: Article
type: Anualidad
type: BFO_0000031
type: BFO_0000001

ANTALGENICS1.15ET
type: ExplotacionLicencia
type: Year2020
type: Year2021
type: BFO_0000020
type: Year2023
type: Year2018
type: Project
type: Year2016
type: BFO_0000001
type: Grant
type: Relationship
type: Year2015
type: TransferenciaTecnologica
type: Anualidad
type: BFO_0000003
type: Proyecto
type: Year2019
type: Thing
included: Moléculas bioactivas 2022
type: Year2017
type: BFO_0000002
type: BFO_0000015
type: 2022

FERNÁNDEZ CARVAJAL, ASIA
type: PersonActive
type: Agent
type: BFO_0000001
type: Person
type: Thing
type: BFO_0000004
type: BFO_0000002
included: Moléculas bioactivas 2022

INNVA2/2022/8
type: ProyectoInvestigacion
type: BFO_0000001
type: Proyecto
type: BFO_0000020
type: BFO_0000002
type: BFO_0000015
type: Grant
type: Year2023
type: Anualidad
type: ERO_0000014
type: Relationship
included: Moléculas bioactivas 2022
type: Project
type: Thing
type: OBI_0000011
type: Year2024
type: BFO_0000003
type: 2022

FERNÁNDEZ BALLESTER, GREGORIO JOAQUIN
type: PersonActive
type: Agent
type: BFO_0000001
type: Person
type: Thing
type: BFO_0000004
type: BFO_0000002
included: Moléculas bioactivas 2022

Modelos traslacionales de dolor: Investigación preclínica sobre el dimorfismo sexual de la migraña crónica.
type: ConferencePaper
type: Thing
type: BFO_0000031
type: Conference
type: BFO_0000001
type: BFO_0000002
included: Moléculas bioactivas 2022
type: Anualidad
type: Document
type: Article
type: IAO_0000030
type: 2022

Design of non-immunogenic peptides that prevent the activation of SARS-CoV-2 nsp14 and nsp16 proteins
type: BFO_0000001
included: Moléculas bioactivas 2022
type: BFO_0000002
type: ConferencePoster
type: Document
type: Conference
type: 2022
type: Anualidad
type: IAO_0000030
type: Thing
type: BFO_0000031

Diseño de péptidos moduladores de las isoformas fosfolipasa C beta
type: BFO_0000001
type: ConferencePoster
type: Anualidad
included: Moléculas bioactivas 2022
type: BFO_0000031
type: 2022
type: Conference
type: BFO_0000002
type: Document
type: IAO_0000030
type: Thing

TRPV1 in chronic pruritus and pain: Soft modulation as a therapeutic strategy
type: IAO_0000030
type: Document
type: BFO_0000031
included: Moléculas bioactivas 2022
type: 2022
type: Thing
type: Anualidad
type: Article
type: AcademicArticle
type: BFO_0000001
type: BFO_0000002

Discovery of new TRPM8 modulators and their therapeutic potential
type: Conference
type: Article
type: BFO_0000002
type: Anualidad
type: BFO_0000031
type: Thing
type: Document
included: Moléculas bioactivas 2022
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type: BFO_0000001
type: 2022
type: ConferencePaper

PROSPERA1.22CC
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type: Year2023
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type: BFO_0000020
type: Anualidad
type: BFO_0000015
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included: Moléculas bioactivas 2022
type: Proyecto
type: Project
type: BFO_0000001
type: ProyectoTerceros
type: 2022
type: BFO_0000002

Design of non-immunogenic peptides that prevent the activation of SARS-CoV_2 nsp14 and nsp16 proteins
type: 2022
type: Anualidad
type: ConferencePoster
type: BFO_0000002
type: Conference
type: BFO_0000001
type: Thing
type: Document
type: IAO_0000030
type: BFO_0000031
included: Moléculas bioactivas 2022

Testosterone-TRPM8 interactions drive pain resilience in a mouse model of chronic migraine
type: 2022
included: Moléculas bioactivas 2022
type: Article
type: BFO_0000031
type: BFO_0000001
type: ConferencePaper
type: Document
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type: Anualidad
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RTI2018-097189-B-C21
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type: 2022
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type: Grant
type: Year2020
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included: Moléculas bioactivas 2022
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Conversión directa de fibroblastos fetales de pulmon a neuronas sensoriales
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type: BFO_0000001
type: IAO_0000030
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included: Moléculas bioactivas 2022

Direct conversion of human foetal lung fibroblasts to sensory neurons.
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type: Anualidad
type: BFO_0000002
type: Conference
type: Thing
type: 2022
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included: Moléculas bioactivas 2022
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ANTALGENICS1.20SC
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Direct conversion of foetal lung fibroblasts to sensory neurons
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FERRER MONTIEL, ANTONIO VICENTE
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included: Moléculas bioactivas 2022

ß-Lactam TRPM8 antagonist RGM8-51 displays analgesic activity in different animal models
type: 2022
type: Article
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type: Thing
type: IAO_0000030
type: BFO_0000001
included: Moléculas bioactivas 2022
type: BFO_0000031
type: Anualidad
type: Document
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Androgenic TRPM8 1 activity drives sexual dimorphism in a murine model of chronic migraine.
type: Document
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type: AcademicArticle
included: Moléculas bioactivas 2022
type: BFO_0000002
type: IAO_0000030
type: BFO_0000001
type: Thing
type: 2022
type: Article
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Paclitaxel in vitro reversibly sensitizes the excitability of IB4(-) and IB4(+) sensory neurons from male and female rats
type: 2022
included: Moléculas bioactivas 2022
type: Anualidad
type: Thing
type: Article
type: AcademicArticle
type: BFO_0000001
type: Document
type: IAO_0000030
type: BFO_0000031
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Cytoskeleton altering drugs and peripheral nerve neurons as a combinatorial therapy for spinal cord injury
type: BFO_0000002
type: BFO_0000001
type: 2022
type: Document
type: IAO_0000030
included: Moléculas bioactivas 2022
type: Anualidad
type: ConferencePoster
type: Conference
type: Thing
type: BFO_0000031

Gender differences in scratching behaviour
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type: Anualidad
type: BFO_0000031
type: ConferencePaper
type: Article
type: BFO_0000001
type: Thing
type: 2022
type: IAO_0000030
type: Conference
type: Document
included: Moléculas bioactivas 2022

Paclitaxel and Oxaliplatin Effects on Pre-clinical In vitro Models of Chemotherapy-Induced Peripheral Neuropathy of Male and Female Rat DRG Neurons
type: Document
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type: BFO_0000001
type: Anualidad
type: Conference
type: IAO_0000030
included: Moléculas bioactivas 2022
type: Thing
type: ConferencePoster
type: 2022
type: BFO_0000031

A topical formulation of a soft TRPV1 antagonist (AG1549) alleviates chemotherapyinduced peripheral neuropathy symptoms.
type: Conference
type: 2022
type: IAO_0000030
type: ConferencePoster
type: Anualidad
type: Document
type: BFO_0000001
type: BFO_0000002
included: Moléculas bioactivas 2022
type: Thing
type: BFO_0000031

Migraine-related vulnerability involves TRPA1 and androgenic TRPM8 activity in mice
type: ConferencePoster
included: Moléculas bioactivas 2022
type: Document
type: BFO_0000031
type: BFO_0000002
type: Thing
type: IAO_0000030
type: Anualidad
type: Conference
type: 2022
type: BFO_0000001

VIDIF22/19
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type: ERO_0000014
type: Relationship
type: BFO_0000015
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included: Moléculas bioactivas 2022
type: Grant
type: BFO_0000002
type: OBI_0000011
type: Anualidad
type: Proyecto
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Direct conversion of human fibroblasts to sensory neurons
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¿CÓMO SE DESENCADENA EL DOLOR TRAS LA QUIMIOTERAPIA? ESTUDIANDO LOS CAMBIOS MOLECULARES PRODUCIDOS POR EL PACLITAXEL SOBRE LOS NOCICEPTORES UTILIZANDO UN MODELO IN VITRO PRECLÍNICO
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