Anualidad
Research Activity Report
Electrospun fibers of Poly(methyl vinyl ether-alt- maleic anhydride) and L-Menthol for treatment of plantar fasciitis
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening
Intra-variability in IB4- and IB4+ DRG neurons: a population of models study
New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models
Thermo TRP ion channels as a key molecular and functional landmark for neuropathic pain transduction in subsets of somatosensory neurons
Paclitaxel and Oxaliplatin Sensitizing Effects and Sex Differences on Pre-Clinical In vitro Models of Chemotherapy-Induced Peripheral Neuropathy
TRPM8 channel antagonists for relieving pain in chemotherapy-induced peropheral neuropathy
Pre-clinical model for the study of gender dimorphism in inflammatory processes during a migraine attack
New chiral heterocyclic amino acid derivatives as TRPM8 antagonists.
ThermoTRP channels in pain sexual dimorphism: new insights for drug intervention.
Conformational buffering underlies functional selection in intrinsically disordered protein regions
Diseño computacional y validación funcional de nuevos péptidos moduladores de las isoformas fosfolipasa C beta
¿Qué parte del cerebro me avisa del picor?
Caracterización de un péptido de diseño con potencial inhibidor del virus del ZIKA
In vitro pre-clinical nociceptor model: useful tool for modelling Chemotherapy Induced-Neuropathic Pain (CIPN)
Los canales iónicos Thermo TRP como clave molecular y funcional para la transducción del dolor neuropático en las neuronas somatosensoriales
In vitro pre-clinical nociceptor model: useful tool for modelling Chemotherapy Induced-Neuropathic Pain
Evaluación del dimorfismo sexual en la sensibilización de TRPA1 durante una crisis de migraña
Development of a compound as neurocosmetic ingredient to alleviate allodynia symptoms induced by chemotherapy-
Oxaliplatin time course effect on a pre-clinical in vitro model of male and female rat DRG neurons.
Amino acid-derived ß¿lactams: TRPM8 antagonists with analgesic activity in different pain models.
New chiral heterocyclic compounds with potent TRPM8 antagonist activity
Modelos traslacionales de dolor: Investigación preclínica sobre el dimorfismo sexual de la migraña crónica.
Design of non-immunogenic peptides that prevent the activation of SARS-CoV-2 nsp14 and nsp16 proteins
Diseño de péptidos moduladores de las isoformas fosfolipasa C beta
TRPV1 in chronic pruritus and pain: Soft modulation as a therapeutic strategy
Discovery of new TRPM8 modulators and their therapeutic potential
Design of non-immunogenic peptides that prevent the activation of SARS-CoV_2 nsp14 and nsp16 proteins
Testosterone-TRPM8 interactions drive pain resilience in a mouse model of chronic migraine
Conversión directa de fibroblastos fetales de pulmon a neuronas sensoriales
Direct conversion of human foetal lung fibroblasts to sensory neurons.
Direct conversion of foetal lung fibroblasts to sensory neurons
ß-Lactam TRPM8 antagonist RGM8-51 displays analgesic activity in different animal models
Androgenic TRPM8 1 activity drives sexual dimorphism in a murine model of chronic migraine.
Paclitaxel in vitro reversibly sensitizes the excitability of IB4(-) and IB4(+) sensory neurons from male and female rats
Cytoskeleton altering drugs and peripheral nerve neurons as a combinatorial therapy for spinal cord injury
Gender differences in scratching behaviour
Paclitaxel and Oxaliplatin Effects on Pre-clinical In vitro Models of Chemotherapy-Induced Peripheral Neuropathy of Male and Female Rat DRG Neurons
A topical formulation of a soft TRPV1 antagonist (AG1549) alleviates chemotherapyinduced peripheral neuropathy symptoms.
Migraine-related vulnerability involves TRPA1 and androgenic TRPM8 activity in mice
Direct conversion of human fibroblasts to sensory neurons
DESCUBRIMIENTO DE NUEVOS MODULADORES DE TRPM8 Y SU POTENCIAL TERAPÉUTICO
Identificación y Caracterización de nuevos moduladores de TRPM8.
Modelo pre-clínico para el estudio de las diferencias de género en procesos inflamatorios durante una crisis de migraña
¿CÓMO SE DESENCADENA EL DOLOR TRAS LA QUIMIOTERAPIA? ESTUDIANDO LOS CAMBIOS MOLECULARES PRODUCIDOS POR EL PACLITAXEL SOBRE LOS NOCICEPTORES UTILIZANDO UN MODELO IN VITRO PRECLÍNICO
RDF description of Moléculas bioactivas 2022 - http://research.umh.es/vivo/pub/memoria/2022/gi_1079