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Research Activity Report
Synthesis and characterization of polymeric nanostructures for drug delivery
Intrinsically disordered proteins in biology: One for all, all for one.
Antioxidant supplementation modulates neutrophil inflammatory response to exercise-induced stress
Structure-based design of novel biphenyl amide antagonists of human transient receptor potential cation channel subfamily M member 8 channels (TRPM8)
The Interaction of Temozolomide with Blood Components Suggests the Potential Use of Human Serum Albumin as a Biomimetic Carrier for the Drug
Variation in Colonoscopy Performance Measures According to Procedure Indication
The isolated armadillo-repeat domain of Plakophilin 1 is a monomer in solution with a low conformational stability
Functionality of beta- adrenergic receptors in patients with cirrhosis treated chronically with non- selective beta-blockers.
Inhibition of insulin secretion by second-generation antipsychotics might mediate prediabetes development.
Synthesis of a library of 3-oxopiperazinium and perhydro-3-oxo-1,4-diazepinium derivatives and identification of bioactive compounds.
Bisphenol-A exposure during pregnancy alters pancreatic ß-cell division and mass in male mice offspring: A role for ERß
Cell death Mechanisms induced by CLytA-DAAO chimeric enzyme in human tumor cell lines
Liver Sinusoidal Endothelial Cells Contribute to Hepatic Antigen-Presenting Cell Function and Th17 Expansion in Cirrhosis.
Fluorescent and thermosensitive nanoparticles for drug delivery and bioimaging
The endocannabinoid system in modulating fear, anxiety and stress
Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity
Sweet Cherry Byproducts Processed by Green Extraction Techniques as a Source of Bioactive Compounds with Antiaging Properties
Identificación y caracterización de nuevos moduladores del canal TRPM8
Del dolor a los canales iónicos: Modelando la neuropatía producida por paclitaxel
PH-dependent solution structure and activity of a reduced form of the host-defense peptide myticin C (Myt C) from the mussel mytilus galloprovincialis
Nanomaterials: Applications in Food, Environmental Remediation, and Bioengineering
Differential Effects of IGF-1R Small Molecule Tyrosine Kinase Inhibitors BMS-754807 and OSI-906 on Human Cancer Cell Lines
Búsqueda de moléculas naturales como potenciales antivirales en ZIKV y DENV mediante herramientas computacionales
Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2¿-O-Methylation of Viral RNA
Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients
Aggregation of 25-hydroxycholesterol in a complex biomembrane. Differences with cholesterol
Papel de ERalpha, ERbeta y GPR30 en la apoptosis en la línea de célula ß INS-1E
Diseño de un biosensor fluorescente para la búsqueda de nuevos antidiabéticos
Integrative Strategy of Testing Systems for Identification of Endocrine Disruptors Inducing Metabolic Disorders¿An Introduction to the OBERON Project
Impacts of food contact chemicals on human health: a consensus statement
TRPM8 determina diferencias sexuales en un modelo murino de Migraña
A small dose of intraarticular triamcinolone plus mepivacaine provides a rapid and sustained relief for gout flares.
BCL-XL, PERO NO EL COMPLEMENTO C3, PROTEGE A LAS CÉLULAS ALFA CONTRA EL ESTRÉS METABÓLICO O LA APOPTOSIS INDUCIDA POR INFLAMACIÓN
Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche
Multi-emission fluorescent nanoplatforms based on lipid conjugated polymer complexes
Structure and functionalities of the human c-reactive protein compared to the zebrafish multigene family of c-reactive-like proteins.
A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability
Calorie restriction improves physical performance and modulates the antioxidant and inflammatory responses to acute exercise
Risk of Cancer in Family Members of Patients with Lynch-Like Syndrome
Interacciones biológicas, una herramienta para encontrar nuevos sistemas de ¿drug delivery¿
Beta-glucan enhances the response to SVCV infection in zebrafish.
PAPEL DEL RECEPTOR DE ESTRÓGENOS ß EN LOS EFECTOS DE LA EXPOSICIÓN PRENATAL AL BISFENOL-A EN LA CÉLULA ß PANCREÁTICA
Evaluación de los mecanismos moleculares que se establecen durante una crisis de migraña a nivel de SNP
Postprandial Lipemia Modulates Pancreatic Alpha-Cell Function in the Prediction of Type 2 Diabetes Development: The CORDIOPREV Study
Fluorene-Based Donor-Acceptor Copolymers Containing Functionalized Benzotriazole Units: Tunable Emission and their Electrical Properties
The Beneficial Effects of Lippia Citriodora Extract on Diet-Induced Obesity in Mice Are Associated with Modulation in the Gut Microbiota Composition
Development of co-poly-(methyl vinyl ether-alt- maleic anhydride) derivates nanocarriers to improve administration of different drugs
Diagnostic yield of early repeat colonoscopy after suboptimal bowel preparation in a fecal immunochemical test-based screening program
Perspectivas de estudio en gerontología y saluden el siglo XXI.
Perspectvas de estudio en gerontología y salud en el siglo XXI
Perspectivas de estudio en gerontologia y salud
Perspectivas de estudio en gerontología y salud en el siglo XXI
The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds
Modulation of Function, Structure and Clustering of K + Channels by Lipids: Lessons Learnt from KcsA
he LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes.
Increasing Versatility of the DNA Vaccines through Modification of the Subcellular Location of Plasmid-Encoded Antigen Expression in the In Vivo Transfected Cells.
Location, Orientation and Aggregation of Bardoxolone-ME, CDDO-ME, in a Complex Phospholipid Bilayer Membrane
Tackling Antibiotic Resistance with Compounds of Natural Origin: A Comprehensive Review
Highly functionalized ß-lactams and 2-ketopiperazines as TRPM8 antagonists with antitumor and antiallodynic activity.
Endocrine disruptors and type 2diabetes: an integrated approach for hazard identification
Early stimulation of TREK channel transcription and activity induced by Oxaliplatin-dependent cytosolic acidification.
Role of ERalpha, ERbeta and GPER1 on INS-1E ß-cell line apoptosis
Nanoestructuras como formas farmacéuticas en terapia antibiótica
Bisphenol A increases excitability in mouse dorsal root ganglion neurons through activation of estrogen receptor ¿ and PI3K.
Surgical Induction of Endometriosis in Female Mice
Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients.
Electrospun Nanomaterials: Applications in Food, Environmental Remediation, and Bioengineering
Design of a fluorescent ¿-glucosidase biosensor based on nanoparticles composed of lipid and conjugated polymer
Investigational drugs in early phase clinical trials targeting thermotransient receptor potential (thermoTRP) channels
ADAPTACIONES DE LA CÉDULA ¿ PANCREÁTICA DURANTE EL FINAL DE LA GESTACIÓN EN EL RATÓN: PAPEL DE LAS HORMONAS GESTACIONALES.
Effects of aging on beta-cell mass and function
Physico-Chemically Distinct Nanomaterials Synthesized from Derivates of a Poly(Anhydride) Diversify the Spectrum of Loadable Antibiotics
Exploration of TRPM8 Binding Sites by Carboline-based Antagonists and Their In Vitro Characterization and in Vivo Analgesic Activities
KV1.3 Interacts with a Calmodulin-Binding Tetraleucine Motif of KCNE4
Identification of the phospholipid binding regions of the envelope E protein of flaviviruses by molecular dynamics.
Desarrollo de un biosensor de a-glucosidasa basado en nanopartículas compuestas por lípido y polímero conjugado
aracterización termodinámica de un péptido contra ZIKV y DENV
Mu and delta opioid receptors play opposite nociceptive and behavioural roles on nerve-injured mice
Regional expression and subcellular localization of the voltage-gated calcium channel ß subunits in the developing mouse brain
Morphological and functional adaptations of pancreatic alpha-cells during late pregnancy in the mouse
The Commonly Overlooked Factor. Commentary on: ¿Environmental Obesogens and their Impact on Susceptibility to Obesity¿
Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol -
Human importin ¿3 and its N-terminal truncated form, without the importin-ß-binding domain, are oligomeric species with a low conformational stability in solution
Armas naturales contra las superbacterias
Conformational Plasticity of the KcsA Channel from Advanced Time-Resolved Homo-FRET Methodologies
Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2020
MODULACIÓN DE LA MASA DE LA CÉLULA ALFA PANCREÁTICA EN UN MODELO MURINO DE DIABETES EXPERIMENTAL
New Synthesis of Mannoside Containing Neoglycoconjugates by Reaction of Propargyl Mannosides with Polyalkylcarboxylated Scaffolds
SAT-715 Bisphenol-A Alters Pancreatic B-Cell Proliferation and Mass in an Estrogen Receptor Beta-Dependent Manner
Improving a Natural Compound: Design of Innovative Neurocosmeceuticals for Sensitive Skin
Developmental profile of SK2 channel expression and function in CA1 neurons.
Thermosensitive and photothermal nanoparticles for bioimaging and controlled drug delivery
DISEÑO Y OPTIMIZACIÓN DE NANOPARTÍCULAS CON APLICACIONES BIOTECNOLÓGICAS: CAPTURA DE CONTAMINANTES, TRANSPORTE Y ALMACENAMIENTO DE BIOMOLECULAS.
Rosemary Diterpenes and Flavanone Aglycones Provide Improved Genoprotection against UV-Induced DNA Damage in a Human Skin Cell Model
Carotenoids from persimmon juice processing
The antimicrobial capacity of Cistus salviifolius and Punica granatum plant extracts against clinical pathogens is related to their polyphenolic composition.
Targeting thermoTRP ion channels: in silico preclinical approaches and opportunities
Conversión directa de fibroblastos humanos a neuronas sensoriales
Bisphenol-S and Bisphenol-F alter mouse pancreatic ß-cell ion channel expression and activity and insulin release through an estrogen receptor ERß mediated pathway
Grupo de Innovación Docente en el Grado de Biotecnología
Zebra fish lacking adaptive immunity acquire an antiviral alert state characterized by upregulated gene expression of apoptosis, multigene families, and interferon-related genes.
Mesa redonda: Másteres para graduados en Farmacia
Concrete perturbation in a 13-year in situ concrete/bentonite interaction from FEBEX experiments. New insight of 2:1 Mg phyllosilicate precipitation at the interface
Enhanced recovery after low- and medium-risk liver transplantation. A single-center prospective observational cohort study
Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain.
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration
Disease-modifying effects of natural ¿9-tetrahydrocannabinol in endometriosis-associated pain
Restricted replication of viral hemorrhagic septicemia virus (VHSV) in a birnavirus-carrier cell culture
A sustainable amperometric biosensor for the analysis of ascorbic, benzoic, gallic and kojic acids through catechol detection. Innovation and signal processing
Compuestos antimicrobianos de origen natural: una oportunidad para el tratamiento de enfermedades infecciosas resistentes a antibióticos
Diseño in silico y validación de moduladores del canal iónico TRAAK
Autophagy-inducing peptides from mammalian VSV and fish VHSV rhabdoviral G glycoproteins (G) as models for the development of new therapeutic molecules.
Quercetin metabolites from Hibiscus sabdariffa contribute to alleviate glucolipotoxicity-induced metabolic stress in vitro
CLytA-DAAO, Free and Immobilized in Magnetic Nanoparticles, Induces Cell Death in Human Cancer Cells
Adaptaciones de la célula alfa pancreática en el envejecimiento y en la diabetes
Neutralization of viral infectivity by zebrafish c-reactive protein isoforms.
Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses
The Emerging Relevance of AIM2 in Liver Disease.
Efecto de la sobreexpresión de BCL-XL en la función y supervivencia de la célula ß pancreática.
Industrial-Scale Study of the Chemical Composition of Olive Oil Process-Derived Matrices
Competitive inhibition of protein adsorption to silica surfaces by their coating with high density charge polyelectrolytes
Moduladores del termorreceptor TRPV1 desactivables metabólicamente en la farmacología
RDF description of Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2020 - http://research.umh.es/vivo/pub/memoria/2020/org_10874