Anualidad
Research Activity Report
Interfering with beta-cells or: how type I interferons are implicated in type 1 diabetes
Modulation of TRPV1 channels: from bench to bedside.
Rainbow trout shape-shifted red blood cells
Contribution of hyperpolarizing ion channels to acute cold hypersensitivity induced by oxaliplatin administration.
In vivo role of TRP channels in an experimental model of chronic migraine.
Natural Compounds as New Cancer Treatments
The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase.
The C-terminal SAM domain of p73 binds to the N terminus of MDM2.
The prebiotic properties of Hibiscus sabdariffa extract contribute to the beneficial effects in diet-induced obesity in mice
Exposure to bisphenol-A induces pancreatic ß-cell apoptosis
The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3
In vitro characterization of a TRPV1 soft antagonist.
Acute phase protein response to viral infection and vaccination
Transdifferentiation and microfluidic chambers as tools to approach the in-vivo sketch of human nociceptors
BCL-XL, but not complement C3, protect alpha-cells against metabolic stress- or proinflammatory-induced apoptosis
Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception
Transcriptome and proteome analyses of red blood cells from rainbow trout challenged with viral haemorrhagic septicaemia virus
A positive allosteric modulator of alpha7 nicotinic receptors with analgesic and neuroprotective activity.
THE STRESS-MEDIATED ANTIPROLIFERATIVE EFFECTS OF MARINE INVERTEBRATE EXTRACTS IN HUMAN COLON CANCER CELL MODELS
Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche
xBCL-XL, but not complement C3, protects alpha cells against metabolic stress- or proinflammatory-induced apoptosis
Modulación de la masa de la célula alfa pancreática en un modelo murino de diabetes autoinmune experimental
DESCUBRIMIENTO Y CARACTERIZACIÓN DE LA ACTIVIDAD ANTIVIRAL INDUCIDA POR LAS MOLÉCULAS TIPO CRP DE PEZ CEBRA (DANIO RERIO)
Antiviral Activity of a Turbot (Scophthalmus maximus) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion
Actual Anti-TNF Trough Levels Relate to Serum IL-10 in Drug-Responding Patients With Crohn's Disease.
Revisiting silibinin as a novobiocin-like Hsp90¿C-terminal inhibitor: Computational modeling and experimental validation.
Fish Red Blood Cells Modulate Immune Genes in Response to Bacterial Inclusion Bodies Made of TNF¿ and a G-VHSV Fragment
Differential effects of chronic exposure to bisphenol A on ion channel activity and expression in mouse pancreatic ß-cells
Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2019
Diseño de péptidos con posible capacidad inhibitoria contra Zika y Dengue
Molecular basis of ion channel modulation: Mapping the conformational states of the outer vestibule of KcsA, a prokaryote potassium channel, using homo-FRET
Industrialización de la granada (Punica granatum L.). Producción de zumo de granada
XV CONGRESO ESTUDIANTES DE FARMACIA (X EDICION INTERNACIONAL) (Congress Organization)
LOS ERITROCITOS NUCLEADOS DE PECES EN LA RESPUESTA INMUNE FRENTE A INFECCIONES VÍRICAS
Toxic Effects of Common Environmental Pollutants in Pancreatic b-Cellsand the Onset of Diabetes Mellitus
EDC disturbance of beta-cells and risk of diabetes
The role of Endocrine Disrupting Chemicals in the etiology of Diabetes Mellitus
Preclinical evaluation of the antimicrobial-immunomodulatory dual action of xenohormetic molecules against Haemophilus influenzae respiratory infection
Editorial: Endocrine Disrupters and Metabolism
Antiproliferative effectsof H.sanguineus extracts in breast ans colon cancer cell lines
Diabetes y desórdenes metabólicos: viejos problemas, nuevas soluciones
Los estrógenos y disruptores endocrinos con actividad estrogénica en la célula ß pancreática y su implicación en la viabilidad celular
Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers.
Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes
Turbot (Scophthalmus maximus) Nk-lysin induces protection against the pathogenic parasite Philasterides dicentrarchi via membrane disruption.
Bisphenol-A modulates ion channel expression and function via estrogen receptor ß in mouse pancreatic beta cells
Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis.
NANOPARTÍCULAS Y NANOFIBRAS DE POLI [METIL VINIL ÉTER ¿ALT¿ (ANHÍDRIDO MALEICO)] (PMVEMA) Y DERIVADOS PARA DRUG DELIVERY
Metabolomic analysis of the effects of a commercial complex biostimulant on pepper crops
Quercetin derivatives from Hibiscus sabdariffa to alleviate glucolipotoxicity-induced metabolic stress
Inhibition of glucolipotoxicity-induced metabolic stress by metabolites from Hibiscus sabdariffa on hypertrophied 3T3-L1 adipocytes
Is TRPA1 Burning Down TRPV1 as Druggable Target for the Treatment of Chronic Pain?
Viral interference between infectious pancreatic necrosis virus and spring viremia of carp virus in zebrafish
Effect of a combination of polyphenols derived from Hibiscus sabdariffa L and Lippia citriodora L on stage I hypertensive patients: A randomized controlled trial
Algunas enseñanzas sobre dinámica de poblaciones. La expansión del arruí y la cabra montés en la Región de Murcia
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration.
Potential role of rainbow trout red blood cells as mediators in the immune response induced by DNA vaccines
Implementación de nuevas herramientas de innovación docente en el Grado de Biotecnología de la UMH: Evaluación del impacto en el rendimiento académico
Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain.
Effects of aging on K+ and Ca2+ currents and glucose-regulated Ca2+ signals in mouse
¿Ganaremos la guerra contra las superbacterias?
Development of an in vitro pre-clinical nociceptor model for studying paclitaxel-induced neuropathic pain
Study Chronic Effect of 17- ß -Estradiol Over Trp Channels In Nociceptor Terminals In Microfluidic Chambers.
ESTUDIO DE LA CAPACIDAD ANTIPROLIFERATIVA EN MODELOS CELULARES DE CÁNCER DE MAMA DE UN EXTRACTO DE HOJA DE OLIVO ENRIQUECIDO EN POLIFENOLES
Plasma proteomic analysis of zebrafish following spring viremia of carp virus infection,
Interfering with ß-cells or: how type I interferons are implicated in type 1 diabetes
Design of multicolour fluorescent nanoparticles based on lipid-conjugated polymer complexes
Multifunctional fluorescent hybrid nanoparticles for controlled drug delivery
Improving a Natural Compound: Design of innovative neurocosmeceuticals for sensitive skin
A capsaicin-based TRPV1 soft antagonist as an anti-pruritic drug candidate
Update on Activities in Endocrine Disruptor Research and Policy
Polyfluorene-Based Multicolor Fluorescent Nanoparticles Activated by Temperature for Bioimaging and Drug Delivery
La microbiota intestinal participa en la activación del inflamasoma durante el desarrollo de daño hepático genotóxico
Epigallocatechin-3-gallate location and interaction with late endosomal and plasma membrane model membranes by molecular dynamics.
Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol
Fluorescence-Based Functional Assays for Ca2+-Permeable ThermoTRP Channels
A capsaicin-based TRPV1 soft antagonist as an anti-pruritic drug candidate.
Single versus double expewrimental bile duct ligation model for inducing bacterial translocation
UV Exposure and Skin Protective Effects of Plant Polyphenols.
A new family of chiral heterocyclic compounds that blocks the TRPM8 activation.
Antioxidant and Photoprotective Activity of Apigenin and its Potassium Salt Derivative in Human Keratinocytes and Absorption in Caco-2 Cell Monolayers
Potential Role of Rainbow Trout Erythrocytes as Mediators in the Immune Response Induced by a DNA Vaccine in Fish.
Desarrollo de nanoplataformas fluorescentes multicolor basadas en complejos lípido-polimero conjugado
Determinants of Severity in Acute Pancreatitis
Ingeniería de proteínas, diseño racional y selección
Desarrollo de nanopartículas fluorescentes multicolor basadas en complejos lípido-polímero conjugado
Homo-FRET studies of potassium channel KcsA: a closer look to selectivity filter dynamics and regulation
Implementation of new teaching innovation tools in the biotechnology degree from the UMH: Evaluation of the degree of impact on academic perfomance
7TH SPANISH-ITALIAN-PORTUGUESE-FRENCH (SIPF) INTERNATIONAL WORKSHOP ON STRUCTURE AND FUNCTION OF ION CHANNELS AND TRANSPORTERS (Congress Organization)
Bisphenol A regulates NaV1.7 ramp currents through activation of estrogen receptor ¿ and PI3K in mouse dorsal root ganglion neurons
Endocrine Disrupting Chemicals in the Aetiology of Diabetes
Implementación de nuevas herramientas de innovación docente en el Grado de Biotecnología de la UMH: Evaluación del grado de satisfacción del alumnado.
BCL-XL, but not complement C3, protects alpha-cells against metabolic stress- or proinflammatory-induced apoptosis
Development of a New Delivery System Based on Drug-Loadable Electrospun Nanofibers for Psoriasis Treatment
La interleucina 6 y el TNFalfa se asocian con el perímetro abdominal y el IMC en la estenosis simple y el Nash, respectivamente
Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity.
VII REUNIÓN DE LA RED ESPAÑOLA DE CANALES IÓNICOS / RECI VII (Congress Organization)
Structure-antioxidant activity relationships of isolated compounds from a lemon verbena extract
A nudibrnach extract interrupt colon cancer progression via ros-mediated ER eestress
Identificación y caracterización de nuevos moduladores de TRPM8
POLIFENOLES DE PLANTAS COMESTIBLES COMO REPROGRAMADORES METABÓLICOS EN CONDICIONES DE GLUCOLIPOTOXICIDAD
Short term BPS exposure effects on metabolic response in adult male C57BL/6 mice
Oestrogen receptor ß mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells
In Silico Approaches for TRP Channel Modulation
Polyphenols from Lippia citriodora as potential agonist of the master energy regulator AMPK with synergistic effects
Evaluation of the degree of student satisfaction
A group II intron-encoded protein interacts with the cellular replicative machinery through the ß-sliding clamp.
Combinación de ingredientes a base de polifenoles vegetales con aplicaciones y patologías asociadas a la obesidad
The Potential Synergistic Modulation of AMPK by Lippia citriodora Compounds as a Target in Metabolic Disorders
Plasma proteomic analysis of zebrafish following spring viremia of carp virus infection
Development of an in vitro pre-clinical nociceptor model for studying paclitaxel-induced neuropathic pain"
IFIT5 participates in the antiviral mechanisms of rainbow trout red blood cells
Accessibility of Cations to the Selectivity Filter of Kcsa in the Inactivated State: An Equilibrium Binding Study
Descubrimiento de nuevas dianas terapéuticas para el tratamiento de la diabetes tipo 1 y tipo 2 basadas en las estrategias de supervivencia de la célula ¿ pancreática.
In hepatic cirrhosis, the systemic levels of short chain fatty acids inversely correlate with the level of endotoxemia, and are negatively associated with an increased inflammatory response, impaired liver function and a higher HVPG
NKEF, an antiviral protein involved in the immune response of rainbow trout red blood cells
EVALUACIÓN DE LOS GENES MGMT, SOCS1 Y SOCS3 COMO MARCADORES MOLECULARES DE QUIMIO Y RADIORRESISTENCIA EN MODELOS CELULARES DE GLIOBLASTOMA HUMANO
Chromatin immunoprecipitation and high throughput sequencing of SVCV-infected zebrafish reveals novel epigenetic histone methylation patterns involved in antiviral immune response.
Effects of aging on alpha- and beta-cell mass and function.
Bisphenol-A modulates ion channel expression and activity in mouse pancreatic beta cell via oestrogen receptor beta (ERbeta)
Dendrimers as Competitors of Protein-Protein Interactions of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1
Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress.
Changes in K+/Ca2+ currents, Ca2+ signals and secretion in pancreatic alpha and beta cells from aged mice.
Synthesis of nanofibers composed of poly(methyl vinyl ether-alt-maleic acid) and derivatives for topical administration of drugs
BISPHENOL-A MODULATES ION CHANNEL EXPRESSION AND FUNCTION VIA ESTROGEN RECEPTOR ¿ IN MOUSE PANCREATIC BETA CELLS
The metabolic and vascular protective effects of olive (Olea europaea L.) leaf extract in diet-induced obesity in mice are related to the amelioration of gut microbiota dysbiosis and to its immunomodulatory properties.
Bacterial DNA translocation contributes to systemic inflammation and to minor changes in the clinical outcome of liver transplantation
IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells.
Bacterial DNA translocation contributes to systemic inflammation and to minor changes in the clinical outcome of liver transplantation.
Circulating levels of butyrate are inversely related to portal hypertension, endotoxemia, and systemic inflammation in patients with cirrhosis.
Relationships Between Chemical Structure and Antioxidant Activity of Isolated Phytocompounds from Lemon Verbena
Structure-based design of novel biphenyl amide antagonists of human Transient Receptor Potential Cation Channel Subfamily M Member 8 channels (TRPM8) with potential implications in the treatment of sensory neuropathies.
ß -Lactam TRPM8 Antagonists Prevent Chemotherapy-Induced Cold Allodynia.
LOS ERITROCITOS NUCLEADOS DE PECES EN LA INMUNIZACIÓN FRENTE A RHABDOVIRUS
Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets
Unconventional actions of environmental estrogens via estrogen receptors
In utero exposure to bisphenol-A disrupts key elements of retinoid system in male mice offspring
Endocrine Disrupting Chemicals and Diabetes Mellitus
Modulation of the KcsA potassium channel by anionic phospholipids: Role of the non-annular arginines
Disruptores endocrinos y resistencia a la insulina
Differential effects of a combination of Hibiscus sabdariffa and Lippia citriodora polyphenols in overweight/obese subjects: A randomized controlled trial
LA AMENAZA SILENCIOSA DE LOS DISRUPTORES ENDOCRINOS: un problema de salud pública
XI JORNADA DE SAN ALBERTO MAGNO (Congress Organization)
Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A.
Industrialización del caqui (Diospyros kaki Thunb.). Producción de zumo de caqui
Transdifferentiation and microfluidic chambers as tools to approach thein-vivosketch of human nociceptors.
En la cirrosis hepática, los niveles sistémicos de ácidos grasos de cadena corta se correlacionan inversamente con el nivel de endotoxemia y se asocian de forma negativa con una mayor respuesta inflamatoria, un mayor deterioro de la función hepática y un m mayor HVPG
The Megalocytivirus RBIV Induces Apoptosis and MHC Class I Presentation in Rock Bream (Oplegnathus fasciatus) Red Blood Cells
Glutathione-dependent enzyme activities of peripheral blood mononuclear cells decrease during the winter season compared with the summer in normal-weight and severely obese adolescents
Antiviral Activity of a Turbot (Scophthalmus maximus) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion.
Mechanisms of blockade of the muscle-type nicotinic receptor by benzocaine, a permanently uncharged local anesthetic
Vitamin C loss kinetics and shelf life study in fruit-based baby foods during post packaging storage
Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers.
Adaptaciones de la célula ¿ pancreática durante el final de la gestación en el ratón: papel de las hormonas gestacionales.
Marine Invertebrate Extracts Induce Colon Cancer Cell Death via ROS-Mediated DNA Oxidative Damage and Mitochondrial Impairment
1¿(2¿,5¿-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1- propanone (RGM079): A Positive Allosteric Modulator of ¿7 Nicotinic Receptors with Analgesic and Neuroprotective Activity
Hydroxycholesterol binds and enhances the anti-viral activities of zebrafish monomeric c-reactive protein isoforms
12TH EBSA 10TH ICBP-IUPAP CONGRESS (Congress Organization)
Improved hemodynamic and liver function in portal hypertensive cirrhotic rats after administration of B. pseudocatenulatum CECT 7765.
RDF description of Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche 2019 - http://research.umh.es/vivo/pub/memoria/2019/org_10874