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Research Activity Report
Revisiting silibinin as a novobiocin-like Hsp90¿C-terminal inhibitor: Computational modeling and experimental validation.
Alfa-sinucleína en LCR mejora el diagnóstico diferencial del deterioro cognitivo leve debido a enfermedad de Alzheimer
Inhibition of glucolipotoxicity-induced metabolic stress by metabolites from Hibiscus sabdariffa on hypertrophied 3T3-L1 adipocytes
Molecular basis of ion channel modulation: Mapping the conformational states of the outer vestibule of KcsA, a prokaryote potassium channel, using homo-FRET
EVALUACIÓN DE LOS GENES MGMT, SOCS1 Y SOCS3 COMO MARCADORES MOLECULARES DE QUIMIO Y RADIORRESISTENCIA EN MODELOS CELULARES DE GLIOBLASTOMA HUMANO
The Potential Synergistic Modulation of AMPK by Lippia citriodora Compounds as a Target in Metabolic Disorders
Viral interference between infectious pancreatic necrosis virus and spring viremia of carp virus in zebrafish
Differential activation of a novel non-canonical, ß-catenin-dependent Wnt pathway controls axon guidance decisions at the midline
Transcriptome and proteome analyses of red blood cells from rainbow trout challenged with viral haemorrhagic septicaemia virus
POLIFENOLES DE PLANTAS COMESTIBLES COMO REPROGRAMADORES METABÓLICOS EN CONDICIONES DE GLUCOLIPOTOXICIDAD
Acetylcholinesterase glycosylation is altered in Alzheimer¿s brain. Role of presenilin 1 and ß-amyloid
Structure-based design of novel biphenyl amide antagonists of human Transient Receptor Potential Cation Channel Subfamily M Member 8 channels (TRPM8) with potential implications in the treatment of sensory neuropathies.
Modulation of TRPV1 channels: from bench to bedside.
Characterization of cerebrospinal fluid BACE1 species
Expression of the cold thermoreceptor TRPM8 in rodent brain thermoregulatory circuits
In Silico Approaches for TRP Channel Modulation
A positive allosteric modulator of alpha7 nicotinic receptors with analgesic and neuroprotective activity.
The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase.
Modulation of the KcsA potassium channel by anionic phospholipids: Role of the non-annular arginines
Acute phase protein response to viral infection and vaccination
A capsaicin-based TRPV1 soft antagonist as an anti-pruritic drug candidate.
Epigallocatechin-3-gallate location and interaction with late endosomal and plasma membrane model membranes by molecular dynamics.
Glutathione-dependent enzyme activities of peripheral blood mononuclear cells decrease during the winter season compared with the summer in normal-weight and severely obese adolescents
Marine Invertebrate Extracts Induce Colon Cancer Cell Death via ROS-Mediated DNA Oxidative Damage and Mitochondrial Impairment
A new family of chiral heterocyclic compounds that blocks the TRPM8 activation.
The Megalocytivirus RBIV Induces Apoptosis and MHC Class I Presentation in Rock Bream (Oplegnathus fasciatus) Red Blood Cells
Effect of a combination of polyphenols derived from Hibiscus sabdariffa L and Lippia citriodora L on stage I hypertensive patients: A randomized controlled trial
In vitro characterization of a TRPV1 soft antagonist.
Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers.
Quercetin derivatives from Hibiscus sabdariffa to alleviate glucolipotoxicity-induced metabolic stress
NKEF, an antiviral protein involved in the immune response of rainbow trout red blood cells
VII REUNIÓN DE LA RED ESPAÑOLA DE CANALES IÓNICOS / RECI VII (Congress Organization)
Relationships Between Chemical Structure and Antioxidant Activity of Isolated Phytocompounds from Lemon Verbena
DESCUBRIMIENTO Y CARACTERIZACIÓN DE LA ACTIVIDAD ANTIVIRAL INDUCIDA POR LAS MOLÉCULAS TIPO CRP DE PEZ CEBRA (DANIO RERIO)
Potential role of rainbow trout red blood cells as mediators in the immune response induced by DNA vaccines
Characterization of cerebrospinal fluid BACE1 as a biomarker for Alzheimer¿s disease
Improving a Natural Compound: Design of innovative neurocosmeceuticals for sensitive skin
Antioxidant and Photoprotective Activity of Apigenin and its Potassium Salt Derivative in Human Keratinocytes and Absorption in Caco-2 Cell Monolayers
A capsaicin-based TRPV1 soft antagonist as an anti-pruritic drug candidate
Evaluation of the degree of student satisfaction
Contribution of hyperpolarizing ion channels to acute cold hypersensitivity induced by oxaliplatin administration.
MACRO Y MICROCOSMOS. Una historia del universo y la vida contada entre la ciencia y el arte
Development of a New Delivery System Based on Drug-Loadable Electrospun Nanofibers for Psoriasis Treatment
Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity.
Antiproliferative effectsof H.sanguineus extracts in breast ans colon cancer cell lines
Implementation of new teaching innovation tools in the biotechnology degree from the UMH: Evaluation of the degree of impact on academic perfomance
Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A.
In vivo role of TRP channels in an experimental model of chronic migraine.
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration.
Potential Role of Rainbow Trout Erythrocytes as Mediators in the Immune Response Induced by a DNA Vaccine in Fish.
¿Podemos predecir la aparición de síntomas psicóticos en los pacientes con enfermedad de Alzheimer en la fase de deterioro cognitivo leve? Estudio preliminar.
The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3
DIFFERENTIAL ACTIVATION OF A NOVEL NON-CANONICAL, ß-CATENIN-DEPENDENT WNT PATHWAY CONTROLS AXON GUIDANCE DECISIONS AT THE MIDLINE
CSF-ApoER2 fragments as a read-out of reelin signaling: Distinct patterns in sporadic and autosomal-dominant Alzheimer disease.
LOS ERITROCITOS NUCLEADOS DE PECES EN LA INMUNIZACIÓN FRENTE A RHABDOVIRUS
Polyphenols from Lippia citriodora as potential agonist of the master energy regulator AMPK with synergistic effects
DEREGULATION OF THE WNT AND TGF-ß SIGNALING PATHWAYS UNDERLIES ZIC2-ASSOCIATED HOLOPROSENCEPHALY
Plasma proteomic analysis of zebrafish following spring viremia of carp virus infection
Implementación de nuevas herramientas de innovación docente en el Grado de Biotecnología de la UMH: Evaluación del grado de satisfacción del alumnado.
El cerebro humano: El universo hecho consciencia
Antiviral Activity of a Turbot (Scophthalmus maximus) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion
Expression of P2X2 purinergic receptor in N2a differentiated cells, as a model to study amyloid beta related pathways
The metabolic and vascular protective effects of olive (Olea europaea L.) leaf extract in diet-induced obesity in mice are related to the amelioration of gut microbiota dysbiosis and to its immunomodulatory properties.
Fluorescence-Based Functional Assays for Ca2+-Permeable ThermoTRP Channels
Structure-antioxidant activity relationships of isolated compounds from a lemon verbena extract
Development of an in vitro pre-clinical nociceptor model for studying paclitaxel-induced neuropathic pain"
IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells.
Mechanisms of blockade of the muscle-type nicotinic receptor by benzocaine, a permanently uncharged local anesthetic
Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain.
7TH SPANISH-ITALIAN-PORTUGUESE-FRENCH (SIPF) INTERNATIONAL WORKSHOP ON STRUCTURE AND FUNCTION OF ION CHANNELS AND TRANSPORTERS (Congress Organization)
Multiple sclerosis drug FTY-720 toxicity is mediated by the heterotypic fusion of organelles in neuroendocrine cells
Metabolomic analysis of the effects of a commercial complex biostimulant on pepper crops
ß -Lactam TRPM8 Antagonists Prevent Chemotherapy-Induced Cold Allodynia.
ESTUDIO DE LA CAPACIDAD ANTIPROLIFERATIVA EN MODELOS CELULARES DE CÁNCER DE MAMA DE UN EXTRACTO DE HOJA DE OLIVO ENRIQUECIDO EN POLIFENOLES
The prebiotic properties of Hibiscus sabdariffa extract contribute to the beneficial effects in diet-induced obesity in mice
Combinación de ingredientes a base de polifenoles vegetales con aplicaciones y patologías asociadas a la obesidad
¿Ganaremos la guerra contra las superbacterias?
12TH EBSA 10TH ICBP-IUPAP CONGRESS (Congress Organization)
Rainbow trout shape-shifted red blood cells
IFIT5 participates in the antiviral mechanisms of rainbow trout red blood cells
Altered glycosylation of acetylcholinesterase on Alzheimer's brain. Role of presenilin 1
Transdifferentiation and microfluidic chambers as tools to approach thein-vivosketch of human nociceptors.
Zic2 regulates Draxin to promote Neural Crest cells delamination
Preclinical evaluation of the antimicrobial-immunomodulatory dual action of xenohormetic molecules against Haemophilus influenzae respiratory infection
Implementación de nuevas herramientas de innovación docente en el Grado de Biotecnología de la UMH: Evaluación del impacto en el rendimiento académico
Ingeniería de proteínas, diseño racional y selección
Homo-FRET studies of potassium channel KcsA: a closer look to selectivity filter dynamics and regulation
Hydroxycholesterol binds and enhances the anti-viral activities of zebrafish monomeric c-reactive protein isoforms
Development of an in vitro pre-clinical nociceptor model for studying paclitaxel-induced neuropathic pain
Transdifferentiation and microfluidic chambers as tools to approach the in-vivo sketch of human nociceptors
Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers.
A nudibrnach extract interrupt colon cancer progression via ros-mediated ER eestress
Measurement of CSF alpha-synuclein improves early differential diagnosis of mild cognitive impairment due to Alzheimer's disease.
1¿(2¿,5¿-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1- propanone (RGM079): A Positive Allosteric Modulator of ¿7 Nicotinic Receptors with Analgesic and Neuroprotective Activity
Study Chronic Effect of 17- ß -Estradiol Over Trp Channels In Nociceptor Terminals In Microfluidic Chambers.
Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets
Mutación stop en ADAM10 (p.Tyr167*) asociada a Alzheimer familiar: el primer correlato clínico de haploinsuficiencia de alfa-secretasa
Aportación de alfa-sinucleína en LCR al diagnóstico de pacientes con demencia con cuerpos de Lewy prodrómica.
DNA methylation profile of different clones of human adipose stem cells does not allow to predict their differentiation potential.
UV Exposure and Skin Protective Effects of Plant Polyphenols.
Fish Red Blood Cells Modulate Immune Genes in Response to Bacterial Inclusion Bodies Made of TNF¿ and a G-VHSV Fragment
Diseño de péptidos con posible capacidad inhibitoria contra Zika y Dengue
Differential effects of a combination of Hibiscus sabdariffa and Lippia citriodora polyphenols in overweight/obese subjects: A randomized controlled trial
NR2B and phospho-NR2B levels correlate with APOE genotype in Alzheimer human brain cortex
LOS ERITROCITOS NUCLEADOS DE PECES EN LA RESPUESTA INMUNE FRENTE A INFECCIONES VÍRICAS
Identificación y caracterización de nuevos moduladores de TRPM8
Pre-analytical stability of novel cerebrospinal fluid biomarkers
Rebound effect in presenilin-1 levels during ¿-secretase inhibition
Stability of Cerebrospinal Fluid Biomarkers during Processing and Biobank Storage
THE STRESS-MEDIATED ANTIPROLIFERATIVE EFFECTS OF MARINE INVERTEBRATE EXTRACTS IN HUMAN COLON CANCER CELL MODELS
XI JORNADA DE SAN ALBERTO MAGNO (Congress Organization)
CSF alpha-synuclein improves early discrimination between Alzheimer¿s disease and Lewy body disease.
Accessibility of Cations to the Selectivity Filter of Kcsa in the Inactivated State: An Equilibrium Binding Study
RDF description of Bioquímica y Biología Molecular 2019 - http://research.umh.es/vivo/pub/memoria/2019/org_102