selected publications
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academic article
- Availability of Authorizations from EMA and FDA for Age-Appropriate Medicines Contained in the WHO Essential Medicines List for Children 2019. PHARMACEUTICS. 316-330. 2020
- Biomimetic Artificial Membrane Permeability Assay over Franz Cell Apparatus Using BCS Model Drugs. PHARMACEUTICS. 988-1002. 2020
- Candesartan Cilexetil In Vitro-In Vivo Correlation: Predictive Dissolution as a Development Tool. PHARMACEUTICS. 633. 2020
- Effect of Common Excipients on Intestinal Drug Absorption in Wistar Rats. MOLECULAR PHARMACEUTICS. 2310-2318. 2020
- Effect of excipients on oral absorption process according to the different gastrointestinal segments. EXPERT OPINION ON DRUG DELIVERY. 1-20. 2020
- Effect of thickener on disintegration, dissolution and permeability of common drug products for elderly patients. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 168-176. 2020
- In vivo predictive dissolution (IPD) for Carbamazepine formulations: Additional evidence regarding the universal biopredictive dissolution medium. . PHARMACEUTICS. 558-579. 2020
- New Insights of Oral Colonic Drug Delivery Systems for Inflammatory Bowel Disease Therapy. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 6502. 2020
- Oral controlled release dosage forms: dissolution versus diffusion. EXPERT OPINION ON DRUG DELIVERY. 791-803. 2020
- Recent developments in cancer therapy and diagnosis. JOURNAL OF PHARMACEUTICAL INVESTIGATION. 349-361. 2020
- Segmental-Dependent Solubility and Permeability as Key Factors Guiding Controlled Release Drug Product Development. PHARMACEUTICS. 295. 2020
- Surfactant-Triggered Molecular Gate Tested on Different Mesoporous Silica Supports for Gastrointestinal Controlled Delivery. NANOMATERIALS. 1290-1308. 2020
- Two-step in vitro-in vivo correlations: Deconvolution and convolution methods, which one gives the best predictability? Comparison with one-step approach. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 185-197. 2020
- Classification of WHO Essential Oral Medicines for Children Applying a Provisional Pediatric Biopharmaceutics Classification System. PHARMACEUTICS. 567-583. 2019
- Covalently crosslinked organophosphorous derivatives-chitosan hydrogel as a drug delivery system for oral administration of camptothecin. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 174-183. 2019
- Double Drug Delivery Using Capped Mesoporous Silica Microparticles for the Effective Treatment of Inflammatory Bowel Disease.. MOLECULAR PHARMACEUTICS. 2418-2429. 2019
- Exploring Bioequivalence of Dexketoprofen Trometamol Drug Products with the Gastrointestinal Simulator (GIS) and Precipitation Pathways Analyses. PHARMACEUTICS. 122-140. 2019
- Impact on intestinal permeability of pediatric hyperosmolar formulations after dilution: Studies with rat perfusion method.. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 154-161. 2019
- Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 1606-1616. 2019
- Investigation to Explain Bioequivalence Failure in Pravastatin Immediate-Release Products.. PHARMACEUTICS. 663-673. 2019
- Ion-pair approach coupled with nanoparticle formation to increase bioavailability of a low permeability charged drug. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 36-42. 2019
- Biopharmaceutical optimization in neglected diseases for paediatric patients by applying the provisional paediatric biopharmaceutical classification system. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2231-2241. 2018
- Closed-Loop Doluisio (Colon, Small Intestine) and Single-Pass Intestinal Perfusion (Colon, Jejunum) in Rat-Biophysical Model and Predictions Based on Caco-2.. PHARMACEUTICAL RESEARCH. 1-12. 2018
- Determination of intestinal permeability using in situ perfusion model in rats: Challenges and advantages to BCS classification applied to digoxin.. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 148-157. 2018
- Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 258-269. 2018
- Giardiasis: Characteristics, Pathogenesis and New Insights About Treatment. CURRENT TOPICS IN MEDICINAL CHEMISTRY. 1287-1303. 2018
- In Vitro Dissolution as a Tool for Formulation Selection: Telmisartan Two-Step IVIVC. MOLECULAR PHARMACEUTICS. 2307-2315. 2018
- Ionic hydrogel based on chitosan crosslinked with 6-Phosphogluconic Trisodium salt. BIOMACROMOLECULES. 1294-1304. 2018
- Long-Circulating Hyaluronan-Based Nanohydrogels as Carriers of Hydrophobic Drugs.. PHARMACEUTICS. 213-228. 2018
- Preclinical models for colonic absorption, application to controlled release formulation development.. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 247-259. 2018
- Smart gated magnetic silica mesoporous particles for targeted colon drug delivery: New approaches for inflammatory bowel diseases treatment. JOURNAL OF CONTROLLED RELEASE. 58-69. 2018
- Comparison of segmental-dependent permeability in human and in situ perfusion model in rat.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 191-196. 2017
- Evaluation of the intestinal permeability of rosemary (Rosmarinus officinalis L.) extract polyphenols and terpenoids in Caco-2 cell monolayers. PLOS ONE. 17206-17207. 2017
- Gated Mesoporous Silica Nanocarriers for a "Two-Step" Targeted System to Colonic Tissue.. MOLECULAR PHARMACEUTICS. 2017
- Investigating drug absorption from the colon: Single-pass vs. Doluisio approaches to in-situ rat large-intestinal perfusion.. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 135-141. 2017
- PLGA nanoparticles are effective to control the colonic release and absorption on ibuprofen.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 1-10. 2017
- Phenolic compounds in rosemary as potential source of bioactive compounds against colorectal cancer: In situ absorption and metabolism study. JOURNAL OF FUNCTIONAL FOODS. 202-210. 2017
- Usefulness of Caco-2/HT29-MTX and Caco-2/HT29-MTX/Raji B Coculture Models To Predict Intestinal and Colonic Permeability Compared to Caco-2 Monoculture.. MOLECULAR PHARMACEUTICS. 1264-1270. 2017
- Assessment of the Regulatory Methods for the Comparison of Highly Variable Dissolution Profiles. AAPS JOURNAL. 1550-1561. 2016
- Development of an ion-pair to improve the colon permeability of a low permeability drug: Atenolol. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 334-340. 2016
- Enhancing Oral Absorption of ß-Lapachone: Progress Till Date.. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 1-9. 2016
- Intestinal Permeability of ß-Lapachone and Its Cyclodextrin Complexes and Physical Mixtures. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 795-806. 2016
- Population pharmacokinetic model of lithium and drug compliance assessment. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 1868-1876. 2016
- Segmental-dependent permeability throughout the small intestine following oral drug administration: Single-pass vs. Doluisio approach to in-situ rat perfusion.. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 201-208. 2016
- . In Situ Perfusion Model in Rat Colon for Drug Absorption Studies: Comparison with Small Intestine and Caco-2 Cell Model . JOURNAL OF PHARMACEUTICAL SCIENCES. 3136-3145. 2015
- Cyclometalated Iminophosphorane Gold(III) and Platinum(II). JOURNAL OF MEDICINAL CHEMISTRY. 5825-5841. 2015
- Drug gastrointestinal absorption in rat: strain and gender differences. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 198-203. 2015
- Exploring different strategies for imbalanced ADME data problem: case study on Caco-2 permeability modeling. MOLECULAR DIVERSITY. 1-17. 2015
- In-situ intestinal rat perfusions for human F-abs prediction and BCS permeability class determination: Investigation of the single-pass vs. the Doluisio experimental approaches. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 1-7. 2015
- Intestinal Permeability of ß-Lapachone and Its Cyclodextrin Complexes and Physical Mixtures.. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 1-12. 2015
- Investigating the Discriminatory Power of BCS-Biowaiver in Vitro Methodology to Detect Bioavailability Differences between Immediate Release Products Containing a Class I. MOLECULAR PHARMACEUTICS. 3167-3174. 2015
- Permeability Study of Polyphenols Derived from a Phenolic-Enriched Hibiscus sabdariffa Extract by UHPLC-ESI-UHR-Qq-TOF-MS. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 18396-18411. 2015
- Semi-physiologic model validation and bioequivalence trials simulation to select the best analyte for acetylsalicylic acid. European journal of pharmaceutical sciences. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 86-94. 2015
- Validation of a semi-physiological model for caffeine in healthy subjects and cirrhotic patients.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 57-63. 2015
- A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 366-373. 2014
- Modified Non-Sink Equation for Permeability Estimation in Cell Monolayers: Comparison with Standard Methods . MOLECULAR PHARMACEUTICS. 1403-1414. 2014
- Tubulin acetylation promoting potency and absorption efficacy of deacetylase inhibitors (2). BRITISH JOURNAL OF PHARMACOLOGY. 1-12. 2014
- Validation of phenol red versus gravimetric method for water reabsorption correction and study of gender differences in Doluisio's absorption technique. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 105-110. 2014
- Variability of Permeability Estimation from Different Protocols of Subculture and Transport Experiments in Cell Monolayers.. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS . 1-11. 2014
- Hydrogels: an interesting strategy for smart drug delivery.. THERAPEUTIC DELIVERY. 157-160. 2013
- Innovative in Vitro Method To Predict Rate and Extent of Drug Delivery to the Brain across the Blood-Brain Barrier . MOLECULAR PHARMACEUTICS. 3822-3831. 2013
- Ion-pair strategy for enabling amifostine oral absorption: Rat in situ and in vivo experiments. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 499-504. 2013
- Mathematical modeling of oral absorption and bioavailability of a fluoroquinolone after its precipitation in the gastrointestinal tract . XENOBIOTICA. 745-754. 2013
- Provisional classification and in silico study of biopharmaceutical system based on caco-2 cell permeability and dose number. MOLECULAR PHARMACEUTICS. 2445-2461. 2013
- Semisynthesis, Cytotoxic Activity, and Oral Availability of New Lipophilic 9-Substituted Camptothecin Derivatives. ACS MEDICINAL CHEMISTRY LETTERS. 86-90. 2013
- The Use of Rule-Based and QSPR Approaches in ADME Profiling: A Case Study on Caco-2 Permeability. MOLECULAR INFORMATICS. 459-479. 2013
- SPR in oral bioavailability: specificity or integrality?. MINI-REVIEWS IN MEDICINAL CHEMISTRY. 534-550. 2012
- A new mathematical approach for the estimation of the AUC and its variability under different experimental designs in preclinical studies.. PHARMACEUTICAL STATISTICS. 1-37. 2011
- Assessment of fexofenadine hydrochloride permeability and dissolution with an anionic surfactant using Caco-2 cells.. PHARMAZIE. 747-753. 2011
- Improvement of effect of water-in-oil microemulsion as an oral delivery system for fexofenadine: in vitro and in vivo studies.. INTERNATIONAL JOURNAL OF NANOMEDICINE. 1631-1640. 2011
- In Silico Prediction of Caco-2 Cell Permeability by a Classification QSAR Approach. MOLECULAR INFORMATICS. 376-385. 2011
- In vitro-in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate.. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 1-21. 2011
- Influence of polyunsaturated fatty acids on Cortisol transport through MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 290-291. 2011
- A new mathematical approach for the estimation of the AUC and its variability under different experimental designs in preclinical studies. PHARMACEUTICAL STATISTICS. 0-37. 2010
- An Exploratory Study of Two Caco-2 Cell Models for Oral Absorption: A Report on Their Within-laboratory and Between-laboratory Variability, and Their Predictive Capacity. ATLA-ALTERNATIVES TO LABORATORY ANIMALS. 2010
- Computer simulations for bioequivalence trials (3): drugs with first-pass metabolism and two metabolic pathways. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2010
- Drug penetration across the blood¿brain barrier: an overview. THERAPEUTIC DELIVERY. 535-562. 2010
- Unique pharmacology of Kar-2, a potential anti-cancer agent: absorption modelling and selective mitotic spindle targeting. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 11-19. 2009
- Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Aciclovir . JOURNAL OF PHARMACEUTICAL SCIENCES. 5061-5073. 2008
- Computer simulations of bioequivalence trials: Selection of design and analyte in BCS drugs with first-pass hepatic metabolism: Part II. Non-linear kinetics. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 1-10. 2008
- Computer simulations of bioequivalence trials: Selection of design and analyte in BCS drugs with first-pass hepatic metabolism: Linear kinetics (I). EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 1-10. 2008
- Progress in the development of early diagnosis and a drug with unique pharmacology to improve cancer therapy. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND. 1-19. 2008
- Unique pharmacology of KAR-2, a potential anti-cancer. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 1-12. 2008
- In situ kinetics modelling of intestinal efflux in rats: functional characterization of segmental diferences and correlation with in vitro results. BIOPHARMACEUTICS & DRUG DISPOSITION. 229-239. 2007
- Tecnologias para conocer la posibilidad de mejorar la biodisponibilidad oral. INDUSTRIA FARMACEUTICA. 58-64. 2007
- A topological Sub-structual Approach for the Prediction of P-Glycoprotein susbtrates. JOURNAL OF PHARMACEUTICAL SCIENCES. 589-606. 2006
- Estudios de biosimulación. FARMAESPAÑA INDUSTRIAL SOLUCIONES DE SOFTWARE. 46-49. 2006
- Kinetic modelling of passive transport and active efflux of a fluoquinolone across Caco-2 cells using a compartmental approach in NONMEM. XENOBIOTICA. 1067-1088. 2005
- Kinetic modelling of the intestinal transport of sarafloxacin. Studies in situ in rat and in vitro in Caco-2 cells. JOURNAL OF DRUG TARGETING. 199-212. 2005
- PAMPA a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 429-441. 2004
- A topological-substructural molecular design (TOPS-MODE) approach to determining pharmacokinetics and pharmacological properties of 6-fluoroquinolones derivatives. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 197-206. 2003
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chapter
- Differential absorption of curcuminoids between free and liposomed curcumin formularions. Curcumin. Clinical uses, health effects and potential complications. 99-111. 2016
- Absorción transdermica: Modelos in vitro. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 321-330. 2015
- Ajuste nolineal por mínimos cuadrados en Excel. Uso de herramienta Solver. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 539-567. 2015
- Cálculo depermeabilidad en rata: perfusión sin recirculación. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 499-504. 2015
- Cálculos de lapermeabilidad intestinal in vitro. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 482-489. 2015
- Cálculos denúmeros adimensionales. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 479-481. 2015
- Cálculos depermeabilidad en células de Franz. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 490-496. 2015
- Cálculos develocidad de disolución. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 505-538. 2015
- Cálculos en bioequivalencia. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 454-478. 2015
- Estudios de permeabilidad en humanos. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 241-265. 2015
- Fundamentoscientíficos del BCS y de la Bioequivalencia in vitro: Aspectos teóricos. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 66-83. 2015
- Importance and applications of cell and tissue-based in vitro models for drug permeability screening in early stages of drug development. In: Concepts and models for drug permeability studies ¿ Cell and tissue-based in vitro culture models.. Woodhead Publishing Series in Biomedicine. 1-15. 2015
- Investigación animal para el desarrollo de nuevos fármacos: reducir, refinar o reemplazar.. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 166-182. 2015
- Perfusion in situ sin recirculación. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 349-359. 2015
- Permeabilidad en cultivos celulares. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 266-299. 2015
- Prediccion de la fraccion oral absorbida. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 45-65. 2015
- Drug Absorption. Encyclopedia of Pharmaceutical Science and Technology. Fourth Edition. Six Volume Set. 1-17. 2013
- CORTISOL TRANSPORT ACROSS BIOLOGICAL BARRIERS. Cortisol: Physiology, Regulation and Health Implications. 1-26. 2012
- Biosimulation Studies. Molecular Biopharmaceutics Aspects of Drug Characterisation, Drug Delivery and Dosage Form Evaluation. 314-363. 2011
- CORTISOL TRANSPORT ACROSS BIOLOGICAL BARRIERS . Cortisol: Physiology, Regulation and Health Implications. 1-25. 2011
- Caco-2 cells for studying Intestinal absorption mechanisims: comparison and correlation with rat model. Caco-2 cells and their uses. 129-163. 2011
- Computational and pharmacoinformatic approaches to oral bioavailability prediction. Oral Bioavailability: Basic principles, advances concepts and aplications. 519-535. 2011
- Computer Simulations as a Tool for Optimizing Bioequivalence Trials. Pharmacokinetics. 1-18. 2011
- VIRTUAL BIOEQUIVALENCE TRIALS AS A TOOL FOR REGULATORY DECISIONS . Mathematical modeling, clustering algorithms and applications. 165-178. 2010
- ASSESSMENT OF STUDENT¿S OWN PERCEPTION OF LEARNING. ICERI 2009. International Conference of Education, Research and Innovation. Proceedings. 5392-5397. 2009
- ASSESSMENT OF THE KNOWLEDGE OF PHDS AND MASTER STUDENTS DURING THIS TRAINING PERIOD. ICERI 2009. International Conference of Education, Research and Innovation. Proceedings. 5358-5363. 2009
- COMPUTER AIDED LEARNING IN BIOPHARMACY. International technology, education and development conference. 2923-2926. 2009
- EDUCATIONAL STRATEGIES FOR THE INCREASING OF CREATIVITY. International technology, education and development conference. 2134-2137. 2009
- EVALUATION OF THE PHD STUDENTS¿ ENGLISH LEVEL. ICERI 2009. International Conference of Education, Research and Innovation. Proceedings. 5364-5370. 2009
- KNOWLEDGE ABOUT EHEA OF THE UNIVERSITARY STUDENTS . ICERI 2009. International Conference of Education, Research and Innovation. Proceedings. 5870-5873. 2009
- PROGRAM PROPOSAL FOR EARLY CONTACT OF PREGRADUATE STUDENTS WITH THE RESEARCH WORLD: OR HOW TO MAKE THE RIGHT DECISION AT THE RIGHT TIME. International technology, education and development conference. 4692-4696. 2009
- TEAMWORK IN LABORATORY PRACTICES. ICERI 2009. International Conference of Education, Research and Innovation. Proceedings. 5968-5971. 2009
- TOWARDS THE EUROPEAN SPACE FOR HIGHER EDUCATION: QUALITY OF THE TUTORIALS. ICERI 2009. International Conference of Education, Research and Innovation. Proceedings. 5387-5390. 2009
- HOW AND WHERE ARE DRUGS ABSORBED?. Biosimulation in Drug Development. 249-280. 2008
- Correlation between in vitro, in situ and in vivo models. Biosimulation in Drug Development. 89-109. 2007
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congress communication
- BCS 1 in vivo BE failures: investigation with in vitro models: Dexketoprofen Trometamol 2020
- BE Discriminant In Vitro dissolution test for Two Ibuprofen Formulations: relevance of buffer strength and fluid volume. 2020
- Candesartan Cilexetil Two Step In Vitro-in Vivo Correlation (ivivc) 2020
- PBPK MODELING AND QUANTITATIVE STRUCTURE-PROPERTY RELATIONSHIPS TO PREDICT DRUG DELIVERY TO THE BRAIN 2020
- Administración oral en pediatría: Impacto de la osmolaridad en la farmacocinética de absorción 2019
- BE Discriminant In Vitro Dissolution Test for Two Ibuprofen Formulations: Relevance of Buffer Strength and Fluid Volume 2019
- Development of in vitro dissolution tools predictive of the in vivo behaviour of pharmaceutical formulations: Candesartan in vitro-in vivo correlation (IVIVC). 2019
- Hidrogeles iónicos basados en 6-fosfogluconato trisódico para aplicación tópica 2019
- In Vitro In Vivo (IVIVC) correlation using the Gastrointestinal Simulator dissolution model (GIS):Case examples Desketoprofen, Etoricoxib and Valsartan 2019
- Ion-pair approach coupled with nanoparticle formation 2019
- NECESIDAD DE LA FORMULACIÓN MAGISTRAL COMO HERRAMIENTA DE TRATAMIENTO EN LA PRÁCTICA CLÍNICA VETERINARIA 2019
- One and Two Step IVIVC for Carbamazepine Formulations: Time Scaling through Dissolution Weibull Parameters Scaling 2019
- Synthesis and characterization of pSi nanoparticles functionalized with hyaluronic acid for IBD 2019
- Determination of the permeability using in situ perfusion model in rat applied to biologically active molecules: digoxin 2018
- Development of a colonic controlled release formulation based on an ion-pair nanosystem 2018
- ESTUDIO DE CONSUMO Y UTILIZACIÓN DE BENZODIAZEPINAS EN LA FARMACIA COMUNITARIA¿.PARTE 2 ¿SON PARA SIEMPRE? 2018
- IMPACT ON ORAL ABSORPTION PHARMACOKINETICS AFTER DILUTION OF HYPEROSMOLAR FORMULATIONS IN PAEDIATRICS 2018
- In vitro dissolution as a tool for formulation selection: Candesartan two-steps IVIVC. 2018
- In vitro-In vivo correlation for Telmisartan 2018
- PLGA nanoparticles are an effective formulation to control the colonic release and absorption on ibuprofen 2018
- Perfil según grado de insomnio de los pacientes que acuden a la farmacia comunitaria por una indicación para insomnio 2018
- Segmental Differences in Oral Drug Absorption: What is happening inside and beyond? 2018
- Usefulness of Caco-2/HT29-MTX and with Raji B co-culture models to Predict Intestinal and Colonic Permeability 2018
- pH-dependent molecular gate mesoporous microparticles for biological control of Giardia intestinalis 2018
- A Provisional Pediatric BCS (pBCS) Classification: Biopharmaceutical Optimization in Neglected Diseases (BOND) for Pediatric Patients 2017
- Dexketoprofen Trometamol USP versus GIS Dissolution and In Vivo Relevance 2017
- Exploring Dissolution, Supersaturation and Precipitation of Posaconazole in the Gastrointestinal Simulator (GIS) In Parallel With Visualization of Precipitated Drug by Microscopy Studies 2017
- Feasibility Study of Ion-Pair Development Approach to Increase Colonic Permeability 2017
- Hidrogeles de quitosan entrecruzados covalentemente con THP como sistemas para la liberacion de fármacos 2017
- In Vitro Dissolution as a Tool for Formulation Selection: Telmisartan Two-Step IVIVC 2017
- Influence of Dissolution/Precipitation Pathways on the Bioequivalence of Salt Containing Products 2017
- Influence of Giardia Infection in Oral Absorption of Analgesics 2017
- Modificación en la absorción Metoprolol en presencia de excipientes 2017
- Modificación en la absorción de antiepilépticos en giardiasis 2017
- Prediccion de la absorción de fármacos en colon de rata mediante el desarrollo de un modelo de perfusion in situ 2017
- Single-Pass Versus Doluisio Method: Comparison of Rat In Situ Perfusion Techniques in Small and Large Intestine 2017
- Drug absorption modifications in Giardiosis 2016
- HIDROGEL INTELIGENTE CARGADO CON METRONIDAZOL PARA EL TRATAMIENTO DE LA GIARDIASIS 2016
- Permeability study of rosemary extract in human intestinal colon adenocarcinoma CACO-2 cells by UHPLC-ESI-UHR-Q-TOF-MS. 2016
- Analisis farmacocinetico poblacional del Litio e identificación de covariables predictoras 2015
- Aumento de la absorcion de paracetamol en presencia de giardia intestinalis 2015
- Clasificacion biofarmaceutica de camptotecina, antitumoral de amplio espectro 2015
- Desarrollo de métodos de disolucion con capacidad predictiva del rendimiento in vivo de formulaciones 2015
- Efecto de los excipientes sobre la permeabilidad de pravastatina y su impacto en la Bioequivalencia 2015
- Influencia estructural de la bioguamidas en los procesos de extraccion empleando acidos carboxilicos 2015
- Microparticulas de silice sensible a pH para el tratamiento de giardiosis 2015
- Modelling of intestinal degradation and absorption of Clavulanic acid from In Vitro and In Situ data. 2015
- PERMEABILITY STUDY OF POLYPHENOLS DERIVED FROM A PHENOLIC-ENRICHED HIBISCUS SABDARIFFA EXTRACT BY UHPLCESI- UHR-Qq-TOF-MS 2015
- Population PK Model of Lithium and Drug Compliance Assessment 2015
- in situ intestinal rat perfussion: single pass vs doluisio technique 2015
- COLON DRUG ABSORPTION USING IN SITU RAT PERFUSION METHOD 2014
- CONTROLLED RELEASE SYSTEMS FOR CHEMOTHERAPY WITH SYSTEMIC ACTIVITY 2014
- Chitosan-based hydrogels for Camptothecin delivery in colon 2014
- DRUG ABSORPTION MODIFICATIONS IN GIARDIASIS 2014
- Dissolution assays for Telmisartan to predict in vivo behaviour 2014
- EVALUACION DE LA CAPACIDAD ABSORBENTE DEL INTESTINO GRUESO PARA COMPUESTOS DE ALTA PERMEABILIDAD 2014
- EXCIPIENT EFFECTS ON BIOEQUIVALENCE OF ZOLPIDEM FORMULATIONS. 2014
- Estudio de la absorcion de compuestos de baja permeabilidad en intestino grueso de rata 2014
- Insilico Biopharmaceutical Systems for Provisional Classification of Oral Drugs 2014
- MALABSORPTION OF AMOXICILLIN IN GIARDIASIS V. 2014
- ORAL ABSORPTION CHARACTERIZATION OF TUBULIN DEACETYLASE INHIBITORS: AGK2 AND TSA 2014
- Semiphysiologic model validation and bioequivalence trials simulation to select the best analyte for acetylsalicylic acid 2014
- Semisynthesis, Cytotoxic Activity and Oral Availability of new lipophilic 9-substituted Camptothecin derivatives 2014
- Validation study of three cell models for intestinal permeability and its variability: Pre-experimental, experimental and post-experimental factors 2014
- CLASIFICACIÓN BIOFARMACÉUTICA DE PRAVASTATINA, ZOLPIDEM Y CLOPERASTINA. PARTE I: PERMEABILIDAD EN MODELO IN VITRO DE CULTIVO CELULAR Caco-2. 2013
- Comparacion de los metodos para la estimacion de la permeabilidad en la clasificacion de farmacos segun la BCS 2013
- Estudio de la influencia de la microbiota en la absorción de isoflavonas 2013
- Innovative in vitro method to predict rate and extent of drug delivery to the brain across the Blood-Brain Barrier 2013
- MODELO IN VITRO DE TRANSPORTE DE SUSTANCIAS A TRAVÉS DE LA BARRERA INTESTINAL EN PRESENCIA DE GIARDIA INTESTINALIS 2013
- MODELOS BASADOS EN REGLAS Y QSPR PARA LA PREDICCIÓN DE LA PERMEABILIDAD EN CACO-2. 2013
- MODIFICACIÓN DEL MODELO NO LINEAL PARA EL CÁLCULO DE LA PERMEABILIDAD EN MONOCAPAS CELULARES 2013
- Modification of Non Sink equation for permeability calculation in cell monolayers 2013
- NANOPARTÍCULAS DE SÍLICE MESOPOROSA PARA MODULAR EL PASO DE SUSTANCIAS A TRAVÉS DE LA BARRERA HEMATOENCEFÁLICA 2013
- OBTENCION DE PARAMETROS DE ABSORCION EN INTESTINO DELGADO Y COLON DE RATA 2013
- Optimización de un sistema in vitro para la evaluación de la giardiosis en la absorción de nutrientes y fármacos 2013
- Permeabilidad intestinal de fármacos esenciales de la OMS mediante modelos de perfusión in situ en rata 2013
- BARRAGE OF QUESTIONS: AN OPTION TO PREPARE THE EXAMS. 4183-4185. 2012
- BEST MARKS ARE OBTAINED BY STUDENTS WHO ATTEND CLASS AND DO THE OPTIONAL ACTIVITIES?. 2599-2599. 2012
- Computer simulations of bioequivalence trials: drugs with sequential metabolism 2012
- DIFFERENCES IN MARKS DEPENDING ON THE CLASS ASSISTANCE. 2260-2262. 2012
- EVALUATION OF THE RELATIONSHIP BETWEEN THE MARK OBTAINED IN PHARMACY DEGREE AND FUTURE SALARY EXPECTATION. 1757-1761. 2012
- EVALUATION OF THE STUDENTS¿ KNOWLEDGE ABOUT SPECIFIC SKILLS IN PHARMACOKINETICS. 2600-2601. 2012
- EVALUATION TOOLS: WHICH IS THE BEST?. 2263-2265. 2012
- INTEREST OF VOLUNTEER TASKS ON HIGHER EDUCATION. 4168-4171. 2012
- Nuevas aproximaciones in silico para la clasificacion de permeabilidad intestinal de fármacos 2012
- ORAL EXPOSITIONS AS EVALUATION TOOL. 4179-4182. 2012
- TEACHING AS A PROFESSION. 2749-2750. 2012
- Three Compartment Model To Describe Atipical Permeability Profiles In CACO-2 Cells 2012
- WHAT IS THE TRUSTWORTHINESS WHICH STUDENTS ANSWER A TEST EXAM?. 1323-1323. 2012
- A QSAR approach to clsify permeability in caco-2 cells 2011
- ASSESSING STUDENTS' ACADEMIC ORTOGRAPHY SKILLS 2011
- Cyclodextrin effect on beta-lapachone intestinal peremability in rats 2011
- E-LEARNING: TEST ON-LINE . 3729-3732. 2011
- Effect of the polyinsaturated fatty acids on BBB 2011
- Excel Solver a powerful tool to understand PK concepts. 3769-3772. 2011
- International cooperation between UMH university and las Villas university-Cuba. 3750-3753. 2011
- PERMEABILITY AND BIODISPONIBILITY OF NEW 2011
- PERSPECTIVES OF LAST COURSE PHARMACY STUDENTS FOR PROFESIONAL FUTURE 2011
- PROBLEM-BASED LEARNING. FIRST STEPS IN PHARMACEUTIC TECHNOLOGY 2011
- Absorción diferencial de curcuminoides de Curcuma longa L. mediante ensayos de absorciónintestinal in situ 2010
- Bioequivalence trials simulation to select the best analyte for drugs with two metabolic pathways 2010
- CLASSIFICATION AND REGRESSION MODELS TO PREDICT HUMAN ORAL BIOAVAILABILITY 2010
- Comparison of Permeability Values Between B-Lapachone Pure and Complexes of BLapachone 2010
- EVALUATION OF THE STUDENTS PERCEPTION ABOUT THE APPLICATION OF THEIR KNOWLEDGE IN THEIR FUTURE 2010
- EXPLOIT OF CLASSES BY STUDENT AND THEIR ASSESSMENT 2010
- GENERIC DEVELOPMENT: THE BIOPHARMACEUTIC CLASSIFICATION SYSTEM 2010
- IN SILICO PREDICTION OF CACO-2 CELL PERMEABILITY BY A CLASSIFICATION QSAR APPROACH. 2010
- In silico contribution to biopharmaceutics classification system 2010
- Influence of PUFA on passive diffusion in a blood brain barrier in vitro model 2010
- METHODS TO ASSESS STUDENTS LEARNING. ADVANTAGES AND DISADVANTAGES 2010
- PRACTICES: A BRIDGE BETWEEN UNIVERSITY AND LABORAL 2010
- SUCCESSFUL COMPLEMENTARY LEARNING RESOURCES 2010
- Scientific posters as learning tool 2010
- THE DEBATE AS A SUCCESSFUL LEARNING TOOL 2010
- THE IMPORTANCE TO DIFUSE HEALTH SCIENCE AND TECHNOLOGY INFORMATION IN ¿LA COMUNIDAD VALENCIANA" 2010
- USE OF VISUAL MEMORY TO INCREASE EFFECTIVE LEARNING 2010
- What is the ark that pupils evaluate themselves 2010
- ASSESSMENT OF STUDENT¿S OWN PERCEPTION OF LEARNING 2009
- ASSESSMENT OF THE KNOWLEDGE OF PHD¿S AND MASTER¿S STUDENTS DURING THIS TRAINING PERIOD 2009
- BIOEQUIVALENCE TRIALS SIMULATION : SELECTING THE MOST SENSITIVE ANALYTE FOR DRUGS WITH PRESYSTEMIC METABOLISM. 2009
- BIOEQUIVALENCE TRIALS SIMULATION TO SELECT THE BEST ANALYTE FOR DRUGS WITH PRESYSTEMIC INTESTINAL AND HEPATIC METABOLISM. 2009
- COMPARACIÓN DEL FACTOR RAZA Y GÉNERO EN LA RATA COMO MODELO ANIMAL DE ABSORCIÓN INTESTINAL 2009
- COMPUTATIONAL MODELS TO EXPLAIN THE RELATIONSHIP AMONG P-GLYCOPROTEIN, CYP3A4 AND BIOAVAILABILITY FROM MOLECULAR STRUCTURE. 2009
- COMPUTER AIDED LEARNING IN BIOPHARMACY 2009
- Comparación del Lucifer Yellow y el manitol como marcadores de la integridad de las monocapas Caco-2 para ensayos de permeabilidad 2009
- DIFFERENCES OF DRUG GASTROINTESTINAL ABSORPTION IN RATS DUE TO BREED AND GENDER FACTORS 2009
- EDUCATIONAL STRATEGIES FOR THE INCREASING OF CREATIVITY 2009
- EVALUATION OF THE PHD STUDENTS¿ ENGLISH LEVEL 2009
- KNOWLEDGE ABOUT EHEA OF THE UNIVERSITARY STUDENTS 2009
- MODELADO DEL TRANSPORTE DEL DERIVADO DE VINBLASTINA KAR-2 EN RATA Y EN CÉLULAS CACO-2. 2009
- P-64-Comparison of permeability transport between in vitro and in situ method 2009
- Program proposal for early contact of pregraduate students with the research world: or how to make the right decision at the right time. 2009
- Simulación de estudios de bioequivalencia de fármacos con dos vías metabólicas para la selección del analito más sensible. 2009
- TEAMWORK IN LABORATORY PRACTICES 2009
- THE ¿MOZART EFFECT¿ IN CANCER THERAPY 2009
- TOWARDS THE EUROPEAN SPACE FOR HIGHER EDUCATION: QUALITY OF THE TUTORIALS 2009
- TRANSPORTE DE CORTISOL A TRAVÉS DE UN MODELO IN VITRO DE LA BARRERA HEMATOENCEFÁLICA. 2009
- Variability of the in vitro intestinal permeability in Caco-2 cell line due to the passage number and direction 2009
- A NEW METHOD FOR ESTIMATING THE COMPLETE AUC AND ITS VARIABILITY IN SPARSE SAMPLING DESIGNS 2008
- ABSORPTION MODELLING FOR KAR-2 2008
- Absorption modelling and selective mitotic spindle targeting of KAR-2 2008
- ESTIMATING THE COMPLETE AUC AND ITS STANDARD ERROR IN SPARSE SAMPLING DESIGN 2008
- Estimating the complete AUC and its standard error in sparse sampling designs 2008
- IMPROVING A PATIENT HEALTH IN CANCER THERAPY THROUGH THE MUSIC 2008
- INNOVACIÓN Y CREATIVIDAD EN LAS AULAS UNIVERSITARIAS: LA ASISTENCIA Y PARTICIPACIÓN DE LOS ESTUDIANTES EN CONGRESOS ESPECIALIZADOS 2008
- LA ESCUCHA MUSICAL PARA EL FOMENTO DEL PENSAMIENTO CREATIVO 2008
- MATHEMATICAL MODELLING OF CORTISOL TRANSPORT THROUGH BLOOD BRAIN BARRIER IN PRESENCE OF EPA 2008
- Mathematical modelling of cortisol transport in presence and absence of EPAs 2008
- SIMULATIONS OF BIOEQUIVALENCE TRIALS USING PHYSIOLOGICAL-PHARMACOKINETIC IN SINGLE DOSE AND STEADY STATE SCENARIOS. WHICH SCENARIOS ARE REFUSABLE? 2008
- Simulations of bioequivalence trials using physiological-pharmacokinetic models with saturable and non-saturable hepatic clearance 2008
- Transport of cortisol in presence of Amitriptyline through blood brain barrier model 2008
- Virtual bioequivalence trials: Design and analyte selection in BCS drugs with hepatic metabolism 2008
- Classical music in cancer therapy 2007
- Cortisol transport through Blood Brain Barrier model in presence of amitriptyline 2007
- Determination of absorption rate constant and bioavailability of several b-ketoesters in rats. 2007
- Effect of Sodium Dodecyl Sulphate on fexofenadine Permeability from the Caco-2 cells 2007
- Effect of Sodium Dodecyl Sulphate on fexofenadine absorption from rat intestine 2007
- How DPA and DHA modulate cortisol transport through blood brain barrier 2007
- Influence of the music over the tumor cells growing 2007
- Mathematical modelling to calculate pharmacokinetics and bioavailability of CNV97101. 2007
- Mathematical modelling to determine absorption mechanism of a new antineoplasic drug (Kar-2) 2007
- Modelo matematico para determinar el perfil farmacocinetico de un compuesto que precipita en estomago y se redisuelve posteriormente 2007
- PARENT DRUG OR METABOLITE IN TRIALS: SIMULATIONS USING PHYSIOLOGICAL-PHARMACOKINETIC MODELS WITH SATURABLE AND NON-SATURABLE HEPATIC CLEARANCE IN SINGLE DOSE AND STEADY STATE SCENARIOS 2007
- Permeability comparison study of vinblastine and a new derivative drug Kar-2. 2007
- Programa de terapia musical en aulas hospitalarias 2007
- Semi-physiological/pharmacokinetic models to characterize parent drug or metabolite in bioequivalence risk. 2007
- Simulations of BE trials using semi-physiological/pharmacokinetic models with saturable and non-saturable hepatic clearance: Single dose and Steady State 2007
- Simulations of Bioequivalence Trials using physiological-pharmacokinetic models with saturable and non-saturable hepatic clearance 2007
- Simulations of bioequivalence trials using physiological-pharmacokinetic in single dose and steady state scenarios. Which scenarios are refusable? 2007
- Study in vitro of absorption of KAR-2, a new vinblastine derivative 2007