selected publications
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academic article
- IVIVC approach based on Carbamazepine Bioequivalence. PHARMAZIE. 449-455. 2017
- Enhancing Oral Absorption of ß-Lapachone: Progress Till Date.. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 1-9. 2016
- Cyclometalated Iminophosphorane Gold(III) and Platinum(II). JOURNAL OF MEDICINAL CHEMISTRY. 5825-5841. 2015
- Drug gastrointestinal absorption in rat: strain and gender differences. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 198-203. 2015
- In vitro¿in vivo correlations: general concepts, methodologies and regulatory applications. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. 1935-1947. 2015
- Intestinal Permeability of ß-Lapachone and Its Cyclodextrin Complexes and Physical Mixtures.. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 1-12. 2015
- Investigating the Discriminatory Power of BCS-Biowaiver in Vitro Methodology to Detect Bioavailability Differences between Immediate Release Products Containing a Class I. MOLECULAR PHARMACEUTICS. 3167-3174. 2015
- Semi-physiologic model validation and bioequivalence trials simulation to select the best analyte for acetylsalicylic acid. European journal of pharmaceutical sciences. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 86-94. 2015
- Validation of a semi-physiological model for caffeine in healthy subjects and cirrhotic patients.. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 57-63. 2015
- A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 366-373. 2014
- Modified Non-Sink Equation for Permeability Estimation in Cell Monolayers: Comparison with Standard Methods . MOLECULAR PHARMACEUTICS. 1403-1414. 2014
- Tubulin acetylation promoting potency and absorption efficacy of deacetylase inhibitors (2). BRITISH JOURNAL OF PHARMACOLOGY. 1-12. 2014
- Variability of Permeability Estimation from Different Protocols of Subculture and Transport Experiments in Cell Monolayers.. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS . 1-11. 2014
- Innovative in Vitro Method To Predict Rate and Extent of Drug Delivery to the Brain across the Blood-Brain Barrier . MOLECULAR PHARMACEUTICS. 3822-3831. 2013
- Ion-pair strategy for enabling amifostine oral absorption: Rat in situ and in vivo experiments. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 499-504. 2013
- Mathematical modeling of oral absorption and bioavailability of a fluoroquinolone after its precipitation in the gastrointestinal tract . XENOBIOTICA. 745-754. 2013
- Semisynthesis, Cytotoxic Activity, and Oral Availability of New Lipophilic 9-Substituted Camptothecin Derivatives. ACS MEDICINAL CHEMISTRY LETTERS. 86-90. 2013
- In Silico Prediction of Caco-2 Cell Permeability by a Classification QSAR Approach. MOLECULAR INFORMATICS. 376-385. 2011
- In vitro-in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate.. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 1-21. 2011
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chapter
- Ajuste nolineal por mínimos cuadrados en Excel. Uso de herramienta Solver. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 539-567. 2015
- Cálculo depermeabilidad en rata: perfusión sin recirculación. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 499-504. 2015
- Cálculos de lapermeabilidad intestinal in vitro. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 482-489. 2015
- Cálculos depermeabilidad en células de Franz. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 490-496. 2015
- Cálculos en bioequivalencia. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 454-478. 2015
- Importance and applications of cell and tissue-based in vitro models for drug permeability screening in early stages of drug development. In:Concepts and models for drug permeability studies ¿ Cell and tissue-based in vitro culture models.. Woodhead Publishing Series in Biomedicine. 1-15. 2015
- Prediccion de la fraccion oral absorbida. Metodologías Biofarmacéuticas en el Desarrollo de Medicamentos. 45-65. 2015
- CORTISOL TRANSPORT ACROSS BIOLOGICAL BARRIERS. Cortisol: Physiology, Regulation and Health Implications. 1-26. 2012
- CORTISOL TRANSPORT ACROSS BIOLOGICAL BARRIERS. Cortisol: Physiology, Regulation and Health Implications. 1-25. 2011
- Caco-2 cells for studying Intestinal absorption mechanisims: comparison and correlation with rat model. Caco-2 cells and their uses. 129-163. 2011
- Computer Simulations as a Tool for Optimizing Bioequivalence Trials. Pharmacokinetics. 1-18. 2011
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congress communication
- Analisis farmacocinetico poblacional del Litio e identificación de covariables predictoras 2015
- Modelling of intestinal degradation and absorption of Clavulanic acid from In Vitro and In Situ data. 2015
- Population PK Model of Lithium and Drug Compliance Assessment 2015
- Carbamazepine level C IVIVC 2014
- ORAL ABSORPTION CHARACTERIZATION OF TUBULIN DEACETYLASE INHIBITORS: AGK2 AND TSA 2014
- Semisynthesis, Cytotoxic Activity and Oral Availability of new lipophilic 9-substituted Camptothecin derivatives 2014
- Simulations of populations with different creatinine clearance range and weight to select the best dose of NV22413 2014
- Validation study of three cell models for intestinal permeability and its variability: Pre-experimental, experimental and post-experimental factors 2014
- Analisis Farmacocinetico Poblacional en Fase I del Farmaco antitumoral NV22413 2013
- Comparacion de los metodos para la estimacion de la permeabilidad en la clasificacion de farmacos segun la BCS 2013
- Innovative in vitro method to predict rate and extent of drug delivery to the brain across the Blood-Brain Barrier 2013
- MODIFICACIÓN DEL MODELO NO LINEAL PARA EL CÁLCULO DE LA PERMEABILIDAD EN MONOCAPAS CELULARES 2013
- Modelo de tres compartimentos para la caracterización de la absorción in vitro de Quinidina en Nonmem 2013
- Modification of Non Sink equation for permeability calculation in cell monolayers 2013
- Simultaneous modelling of Fexofenadine in in vitro cell culture and in situ experiments 2013
- BARRAGE OF QUESTIONS: AN OPTION TO PREPARE THE EXAMS. 4183-4185. 2012
- BEST MARKS ARE OBTAINED BY STUDENTS WHO ATTEND CLASS AND DO THE OPTIONAL ACTIVITIES?. 2599-2599. 2012
- Computer simulations of bioequivalence trials: drugs with sequential metabolism 2012
- DIFFERENCES IN MARKS DEPENDING ON THE CLASS ASSISTANCE. 2260-2262. 2012
- EVALUATION OF THE RELATIONSHIP BETWEEN THE MARK OBTAINED IN PHARMACY DEGREE AND FUTURE SALARY EXPECTATION. 1757-1761. 2012
- EVALUATION OF THE STUDENTS¿ KNOWLEDGE ABOUT SPECIFIC SKILLS IN PHARMACOKINETICS. 2600-2601. 2012
- EVALUATION TOOLS: WHICH IS THE BEST?. 2263-2265. 2012
- INTEREST OF VOLUNTEER TASKS ON HIGHER EDUCATION. 4168-4171. 2012
- Nuevas aproximaciones in silico para la clasificacion de permeabilidad intestinal de fármacos 2012
- ORAL EXPOSITIONS AS EVALUATION TOOL. 4179-4182. 2012
- TEACHING AS A PROFESSION. 2749-2750. 2012
- Three Compartment Model To Describe Atipical Permeability Profiles In CACO-2 Cells 2012
- WHAT IS THE TRUSTWORTHINESS WHICH STUDENTS ANSWER A TEST EXAM?. 1323-1323. 2012